IL259010A - Chimeric post-transcriptional regulatory element - Google Patents
Chimeric post-transcriptional regulatory elementInfo
- Publication number
- IL259010A IL259010A IL259010A IL25901018A IL259010A IL 259010 A IL259010 A IL 259010A IL 259010 A IL259010 A IL 259010A IL 25901018 A IL25901018 A IL 25901018A IL 259010 A IL259010 A IL 259010A
- Authority
- IL
- Israel
- Prior art keywords
- regulatory element
- transcriptional regulatory
- chimeric post
- chimeric
- post
- Prior art date
Links
- 230000001124 posttranscriptional effect Effects 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/106—Plasmid DNA for vertebrates
- C12N2800/107—Plasmid DNA for vertebrates for mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/30—Vector systems having a special element relevant for transcription being an enhancer not forming part of the promoter region
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562246841P | 2015-10-27 | 2015-10-27 | |
| PCT/US2016/059151 WO2017075237A2 (en) | 2015-10-27 | 2016-10-27 | Chimeric post-transcriptional regulatory element |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL259010A true IL259010A (en) | 2018-06-28 |
Family
ID=58561919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL259010A IL259010A (en) | 2015-10-27 | 2018-04-29 | Chimeric post-transcriptional regulatory element |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10190135B2 (enExample) |
| EP (1) | EP3368672B1 (enExample) |
| JP (1) | JP2018534946A (enExample) |
| CN (1) | CN108291238A (enExample) |
| IL (1) | IL259010A (enExample) |
| WO (1) | WO2017075237A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11713468B2 (en) | 2017-08-02 | 2023-08-01 | Dna Twopointo Inc. | DNA vectors and elements for sustained gene expression in eukaryotic cells |
| CN113383081B (zh) * | 2018-12-07 | 2025-04-01 | 赛尔希恩公司 | 基质附着区和促进基因表达的用途 |
| JP2022536692A (ja) | 2019-06-11 | 2022-08-18 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | 調節不全の血漿カリクレインによって媒介される疾患の治療のための抗体のアデノ随伴ウイルスベクター送達 |
| EP4048800A1 (en) | 2019-10-23 | 2022-08-31 | Shire Human Genetic Therapies, Inc. | Adeno-associated virus vectors based gene therapy for hereditary angioedema |
| CN116829595A (zh) | 2020-12-16 | 2023-09-29 | 武田药品工业株式会社 | 用于治疗由失调的血浆激肽释放酶介导的疾病的抗体的腺相关病毒载体递送 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136597A (en) * | 1997-09-18 | 2000-10-24 | The Salk Institute For Biological Studies | RNA export element |
| WO2005056057A1 (en) * | 2003-12-04 | 2005-06-23 | Childrens Hospital Los Angeles Research Institute | Minimal lentiviral vector system |
| US9943611B2 (en) * | 2012-11-01 | 2018-04-17 | California Institute Of Technology | Reversible gene expression |
| CA3246595A1 (en) * | 2014-04-09 | 2025-07-08 | Dna Twopointo Inc | Enhanced polynucleotide constructs for eukaryotic gene expression |
| SI3689899T1 (sl) * | 2014-04-25 | 2022-01-31 | 2Seventy Bio, Inc. | MND promotor kimeričnih antigenskih receptorjev |
-
2016
- 2016-10-27 CN CN201680068524.1A patent/CN108291238A/zh active Pending
- 2016-10-27 WO PCT/US2016/059151 patent/WO2017075237A2/en not_active Ceased
- 2016-10-27 JP JP2018542687A patent/JP2018534946A/ja active Pending
- 2016-10-27 US US15/335,930 patent/US10190135B2/en active Active
- 2016-10-27 EP EP16860800.8A patent/EP3368672B1/en active Active
-
2018
- 2018-04-29 IL IL259010A patent/IL259010A/en unknown
- 2018-12-11 US US16/216,636 patent/US20190309322A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN108291238A (zh) | 2018-07-17 |
| US20170114363A1 (en) | 2017-04-27 |
| WO2017075237A2 (en) | 2017-05-04 |
| US10190135B2 (en) | 2019-01-29 |
| JP2018534946A (ja) | 2018-11-29 |
| WO2017075237A3 (en) | 2017-06-22 |
| US20190309322A1 (en) | 2019-10-10 |
| EP3368672A2 (en) | 2018-09-05 |
| EP3368672A4 (en) | 2019-03-27 |
| EP3368672B1 (en) | 2020-11-25 |
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