IL256383B2 - btla fusion protein agonists and uses thereof - Google Patents
btla fusion protein agonists and uses thereofInfo
- Publication number
- IL256383B2 IL256383B2 IL256383A IL25638317A IL256383B2 IL 256383 B2 IL256383 B2 IL 256383B2 IL 256383 A IL256383 A IL 256383A IL 25638317 A IL25638317 A IL 25638317A IL 256383 B2 IL256383 B2 IL 256383B2
- Authority
- IL
- Israel
- Prior art keywords
- hvem
- protein
- btla
- fusion protein
- cells
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US201562187105P | 2015-06-30 | 2015-06-30 | |
| PCT/US2016/040108 WO2017004213A1 (en) | 2015-06-30 | 2016-06-29 | Btla fusion protein agonists and uses thereof |
Publications (3)
| Publication Number | Publication Date |
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| IL256383A IL256383A (en) | 2018-02-28 |
| IL256383B IL256383B (en) | 2022-11-01 |
| IL256383B2 true IL256383B2 (en) | 2023-03-01 |
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| IL256383A IL256383B2 (en) | 2015-06-30 | 2016-06-29 | btla fusion protein agonists and uses thereof |
| IL297395A IL297395B2 (en) | 2015-06-30 | 2016-06-29 | Agonists for BTLA fusion proteins and uses thereof |
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| Application Number | Title | Priority Date | Filing Date |
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| IL297395A IL297395B2 (en) | 2015-06-30 | 2016-06-29 | Agonists for BTLA fusion proteins and uses thereof |
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| JP (4) | JP7116285B2 (enExample) |
| KR (2) | KR20240110000A (enExample) |
| CN (2) | CN114853903A (enExample) |
| AU (3) | AU2016286108B2 (enExample) |
| BR (1) | BR112017028316A2 (enExample) |
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| MX (1) | MX2018000073A (enExample) |
| SG (1) | SG10201913567QA (enExample) |
| WO (1) | WO2017004213A1 (enExample) |
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| PT3247728T (pt) | 2015-01-20 | 2020-07-16 | Igm Biosciences Inc | Moléculas de ligação do recetor da superfamília do fator de necrose tumoral (fnt) e utilização das mesmas |
| AU2016286108B2 (en) | 2015-06-30 | 2021-03-11 | Pfizer Inc. | BTLA fusion protein agonists and uses thereof |
| GB201820554D0 (en) | 2018-12-17 | 2019-01-30 | Univ Oxford Innovation Ltd | BTLA antibodies |
| GB202008860D0 (en) | 2020-06-11 | 2020-07-29 | Univ Oxford Innovation Ltd | BTLA antibodies |
| AU2023212896A1 (en) * | 2022-01-29 | 2024-08-22 | Hifibio, Inc. | Antibody against btla and uses thereof |
| WO2023215560A1 (en) | 2022-05-05 | 2023-11-09 | Atoosa Corporation | Tumor cell/immune cell multivalent receptor engager – bio-nanoparticle (timre-bnp) |
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| WO2006063067A2 (en) * | 2004-12-09 | 2006-06-15 | La Jolla Institute For Allergy And Immunology | Novel tnf receptor regulatory domain |
| WO2013074738A1 (en) * | 2011-11-15 | 2013-05-23 | Sanford-Burnham Medical Research Institute | Compositions and methods for treating autoimmune and inflammatory disorders |
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| WO2007001459A2 (en) | 2004-11-15 | 2007-01-04 | Washington University | Compositions and methods for modulating lymphocyte activity |
| US8546541B2 (en) | 2002-06-20 | 2013-10-01 | Washington University | Compositions and methods for modulating lymphocyte activity |
| US20030235580A1 (en) | 2002-06-24 | 2003-12-25 | Fen Zhang | Amniotic membrane mediated delivery of bioactive molecules |
| US7153950B2 (en) | 2002-10-25 | 2006-12-26 | Genentech, Inc. | Nucleic acids encoding an immune related polypeptide |
| WO2010006071A1 (en) * | 2008-07-08 | 2010-01-14 | La Jolla Institute For Allergy And Immunology | Hvem/btla, hvem/cd160 and hvem/gd cis complexes and methods of use |
| US8349320B2 (en) * | 2004-12-09 | 2013-01-08 | La Jolla Institute For Allergy And Immunology | Compositions and methods for modulating responses mediated or associated with BTLA activity |
| WO2007010692A1 (ja) | 2005-07-19 | 2007-01-25 | Japan Science And Technology Agency | Ｈｖｅｍ及びｂｔｌａを標的とした炎症性腸疾患治療用医薬組成物及び治療方法 |
| MX2009005189A (es) | 2006-11-15 | 2009-06-30 | Medarex Inc | Anticuerpos humanos monoclonales para btla y metodos de uso. |
| US8318662B2 (en) | 2009-03-16 | 2012-11-27 | Korea Institute Of Radiological & Medical Sciences | Protein increasing cell infectivity of herpes simplex virus and use thereof |
| US8303952B2 (en) | 2009-06-08 | 2012-11-06 | Washington University | Methods for inducing in vivo tolerance |
| CA2769473A1 (en) * | 2009-07-31 | 2011-02-03 | N.V. Organon | Fully human antibodies to btla |
| JP2016530298A (ja) | 2013-09-05 | 2016-09-29 | サンフォード−バーンハム メディカル リサーチ インスティテュート | γδＴ細胞の調節 |
| KR20170134525A (ko) | 2015-04-02 | 2017-12-06 | 메모리얼 슬로안-케터링 캔서 센터 | Tnfrsf14 / hvem 단백질 및 이의 이용 방법 |
| EP3288587A4 (en) | 2015-04-29 | 2018-09-12 | Sanford-Burnham Medical Research Institute | Modulation of immune response using btla agonist antibodies |
| AU2016286108B2 (en) | 2015-06-30 | 2021-03-11 | Pfizer Inc. | BTLA fusion protein agonists and uses thereof |
| CA3013333A1 (en) | 2016-02-26 | 2017-08-31 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Antibodies having specificity for btla and uses thereof |
| US12145993B2 (en) | 2016-06-08 | 2024-11-19 | Shanghai Jiao Tong University School Of Medicine | Sequence of antibody heavy chain constant region for enhancing agonistic antibody activity |
| US12281339B2 (en) | 2016-07-05 | 2025-04-22 | Polaris Group | Combination cancer immunotherapies with arginine depletion agents |
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| MY200973A (en) | 2017-04-11 | 2024-01-26 | Inhibrx Inc | Multispecific Polypeptide Constructs Having Constrained Cd3 Binding And Methods Of Using The Same |
| US20200140547A1 (en) | 2017-05-26 | 2020-05-07 | The Johns Hopkins University | Multifunctional antibody-ligand traps to modulate immune tolerance |
| AU2018355487B2 (en) | 2017-10-27 | 2023-09-21 | Shanghai Yao Yuan Biotechnology Co., Ltd. | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 |
| WO2019094559A2 (en) | 2017-11-09 | 2019-05-16 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor superfamily polypeptides |
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| JP7097465B2 (ja) | 2018-06-19 | 2022-07-07 | アルモ・バイオサイエンシーズ・インコーポレイテッド | キメラ抗原受容体細胞療法と併用するｉｌ－１０剤の組成およびその使用方法 |
| AU2019293589A1 (en) | 2018-06-29 | 2021-01-21 | Alector Llc | Anti-SIRP-beta1 antibodies and methods of use thereof |
| WO2020041361A1 (en) | 2018-08-20 | 2020-02-27 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor superfamily polypeptides |
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| EP3880711A4 (en) | 2018-11-15 | 2022-12-28 | The General Hospital Corporation | Agonistic tumor necrosis factor receptor superfamily polypeptides |
-
2016
- 2016-06-29 AU AU2016286108A patent/AU2016286108B2/en active Active
- 2016-06-29 CN CN202210348320.0A patent/CN114853903A/zh active Pending
- 2016-06-29 SG SG10201913567QA patent/SG10201913567QA/en unknown
- 2016-06-29 EP EP16818691.4A patent/EP3317297A4/en active Pending
- 2016-06-29 US US15/737,259 patent/US10961297B2/en active Active
- 2016-06-29 IL IL256383A patent/IL256383B2/en unknown
- 2016-06-29 IL IL297395A patent/IL297395B2/en unknown
- 2016-06-29 BR BR112017028316-6A patent/BR112017028316A2/en active Search and Examination
- 2016-06-29 WO PCT/US2016/040108 patent/WO2017004213A1/en not_active Ceased
- 2016-06-29 EA EA201890171A patent/EA201890171A1/ru unknown
- 2016-06-29 JP JP2017568205A patent/JP7116285B2/ja active Active
- 2016-06-29 MX MX2018000073A patent/MX2018000073A/es unknown
- 2016-06-29 CA CA2990885A patent/CA2990885A1/en active Pending
- 2016-06-29 KR KR1020247017225A patent/KR20240110000A/ko active Pending
- 2016-06-29 CN CN201680049768.5A patent/CN108026159B9/zh active Active
- 2016-06-29 KR KR1020187002960A patent/KR102669985B1/ko active Active
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2021
- 2021-03-01 US US17/188,912 patent/US11939367B2/en active Active
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- 2021-06-08 AU AU2021203768A patent/AU2021203768B2/en active Active
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2022
- 2022-07-20 JP JP2022115473A patent/JP7559013B2/ja active Active
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2023
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2024
- 2024-02-15 US US18/442,988 patent/US20240247047A1/en active Pending
Patent Citations (3)
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| WO2006054961A2 (en) * | 2004-11-12 | 2006-05-26 | Genentech, Inc. | Novel composition and methods for the treatment of immune related diseases |
| WO2006063067A2 (en) * | 2004-12-09 | 2006-06-15 | La Jolla Institute For Allergy And Immunology | Novel tnf receptor regulatory domain |
| WO2013074738A1 (en) * | 2011-11-15 | 2013-05-23 | Sanford-Burnham Medical Research Institute | Compositions and methods for treating autoimmune and inflammatory disorders |
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| GONZALEZ, LINO C., ET AL., A CORECEPTOR INTERACTION BETWEEN THE CD28 AND TNF RECEPTOR FAMILY MEMBERS B AND T LYMPHOCYTE ATTENUATOR AND HERPESVIRUS ENTRY MEDIATOR., 31 December 2005 (2005-12-31) * |
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