IL255351A0 - Astrocyte biomarkers of trauma and neurotrauma - Google Patents
Astrocyte biomarkers of trauma and neurotraumaInfo
- Publication number
- IL255351A0 IL255351A0 IL255351A IL25535117A IL255351A0 IL 255351 A0 IL255351 A0 IL 255351A0 IL 255351 A IL255351 A IL 255351A IL 25535117 A IL25535117 A IL 25535117A IL 255351 A0 IL255351 A0 IL 255351A0
- Authority
- IL
- Israel
- Prior art keywords
- traumatome
- astrocyte
- neurotrauma
- biomarkers
- neurotrauma biomarkers
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/01—Methyltransferases (2.1.1)
- C12Y201/01259—[Fructose-bisphosphate aldolase]-lysine N-methyltransferase (2.1.1.259)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/40—Disorders due to exposure to physical agents, e.g. heat disorders, motion sickness, radiation injuries, altitude sickness, decompression illness
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562157389P | 2015-05-05 | 2015-05-05 | |
| PCT/US2016/031043 WO2016179426A1 (en) | 2015-05-05 | 2016-05-05 | Astrocyte traumatome and neurotrauma biomarkers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL255351A0 true IL255351A0 (en) | 2017-12-31 |
Family
ID=57218432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL255351A IL255351A0 (en) | 2015-05-05 | 2017-10-31 | Astrocyte biomarkers of trauma and neurotrauma |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10557859B2 (https=) |
| EP (1) | EP3292414B1 (https=) |
| JP (1) | JP6839854B2 (https=) |
| CN (1) | CN107864671A (https=) |
| ES (1) | ES2873509T3 (https=) |
| IL (1) | IL255351A0 (https=) |
| WO (1) | WO2016179426A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107864671A (zh) * | 2015-05-05 | 2018-03-30 | 加利福尼亚大学董事会 | 星形细胞创伤节和神经创伤生物标志物 |
| WO2018217792A1 (en) * | 2017-05-23 | 2018-11-29 | Immunarray USA, Inc. | Biomarker levels and neuroimaging for detecting, monitoring and treating brain injury or trauma |
| JP2021503610A (ja) * | 2017-11-16 | 2021-02-12 | ブレインボックス ソルーションズ、インコーポレイテッドＢｒａｉｎｂｏｘ Ｓｏｌｕｔｉｏｎｓ， Ｉｎｃ． | 神経損傷および／または疾患のタンパク質バイオマーカー指標及びその使用の方法 |
| CA3084064A1 (en) | 2017-12-29 | 2019-07-04 | Abbott Laboratories | Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury |
| EP4053559A1 (en) * | 2021-03-01 | 2022-09-07 | Consorcio Centro de Investigación Biomédica en Red, M.P. (CIBER) | Methods for the measurement of protein c and activated protein c |
| WO2026068747A1 (en) * | 2024-09-26 | 2026-04-02 | Centre Hospitalier Universitaire Vaudois (C.H.U.V.) | Astrocytic phosphoprotein (pea-15) for use in the treatment and/or prevention of a neuronal disorder |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8492107B2 (en) * | 2004-04-15 | 2013-07-23 | University Of Florida Research Foundation, Inc. | Neural proteins as biomarkers for nervous system injury and other neural disorders |
| GB0414798D0 (en) * | 2004-07-01 | 2004-08-04 | Paradigm Therapeutics Ltd | Receptor |
| WO2007136617A2 (en) * | 2006-05-18 | 2007-11-29 | Walter Reed Army Institute Of Research (Wrair) | Endothelial-monocyte activating polypeptide ii, a biomarker for use in diagnosis of brain injury |
| CN101983337A (zh) * | 2008-02-04 | 2011-03-02 | 班扬生物标记公司 | 用于诊断或治疗脑损伤的方法 |
| EP3355059A3 (en) | 2009-06-19 | 2018-09-26 | Banyan Biomarkers, Inc. | Biomarker assay of neurological condition |
| KR101211280B1 (ko) * | 2010-03-26 | 2012-12-11 | 가톨릭대학교 산학협력단 | 신규한 뇌손상 질환 진단용 마커 및 이의 용도 |
| CN103118698A (zh) | 2010-05-28 | 2013-05-22 | 意识-Nrg公司 | 神经调节素同种型，神经调节素多肽和其使用 |
| EP2628013B1 (en) | 2010-10-14 | 2019-06-12 | The Johns Hopkins University | Biomarkers of brain injury |
| US20170023591A1 (en) | 2014-04-07 | 2017-01-26 | Iron Horse Diagnostics, Inc. | Traumatic Brain Injury and Neurodegenerative Biomarkers, Methods, and Systems |
| AU2015322029A1 (en) | 2014-09-25 | 2017-04-27 | Oxeia Biopharmaceuticals, Inc. | Methods of treating traumatic brain injury |
| CN107864671A (zh) * | 2015-05-05 | 2018-03-30 | 加利福尼亚大学董事会 | 星形细胞创伤节和神经创伤生物标志物 |
-
2016
- 2016-05-05 CN CN201680032940.6A patent/CN107864671A/zh active Pending
- 2016-05-05 WO PCT/US2016/031043 patent/WO2016179426A1/en not_active Ceased
- 2016-05-05 ES ES16790108T patent/ES2873509T3/es active Active
- 2016-05-05 US US15/570,982 patent/US10557859B2/en active Active
- 2016-05-05 EP EP16790108.1A patent/EP3292414B1/en active Active
- 2016-05-05 JP JP2017557192A patent/JP6839854B2/ja active Active
-
2017
- 2017-10-31 IL IL255351A patent/IL255351A0/en unknown
-
2019
- 2019-12-16 US US16/716,095 patent/US11249094B2/en active Active
-
2022
- 2022-01-06 US US17/647,289 patent/US12339289B2/en active Active
-
2025
- 2025-05-02 US US19/197,759 patent/US20260110699A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3292414A4 (en) | 2018-09-26 |
| ES2873509T3 (es) | 2021-11-03 |
| US10557859B2 (en) | 2020-02-11 |
| JP2018523092A (ja) | 2018-08-16 |
| EP3292414B1 (en) | 2021-04-07 |
| EP3292414A1 (en) | 2018-03-14 |
| US20220299531A1 (en) | 2022-09-22 |
| US11249094B2 (en) | 2022-02-15 |
| WO2016179426A1 (en) | 2016-11-10 |
| US20180364259A1 (en) | 2018-12-20 |
| US20200278359A1 (en) | 2020-09-03 |
| JP6839854B2 (ja) | 2021-03-17 |
| CN107864671A (zh) | 2018-03-30 |
| US12339289B2 (en) | 2025-06-24 |
| US20260110699A1 (en) | 2026-04-23 |
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