IL254424A0 - Disubstituted heterocyclic tricyclic compounds - Google Patents
Disubstituted heterocyclic tricyclic compoundsInfo
- Publication number
- IL254424A0 IL254424A0 IL254424A IL25442417A IL254424A0 IL 254424 A0 IL254424 A0 IL 254424A0 IL 254424 A IL254424 A IL 254424A IL 25442417 A IL25442417 A IL 25442417A IL 254424 A0 IL254424 A0 IL 254424A0
- Authority
- IL
- Israel
- Prior art keywords
- heterocyclic compounds
- tricyclic heterocyclic
- substituted tricyclic
- substituted
- compounds
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562134769P | 2015-03-18 | 2015-03-18 | |
| PCT/US2016/022737 WO2016149436A1 (en) | 2015-03-18 | 2016-03-17 | Substituted tricyclic heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL254424A0 true IL254424A0 (en) | 2017-11-30 |
Family
ID=55640932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL254424A IL254424A0 (en) | 2015-03-18 | 2017-09-11 | Disubstituted heterocyclic tricyclic compounds |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10189840B2 (enExample) |
| EP (1) | EP3271360B1 (enExample) |
| JP (1) | JP6793657B2 (enExample) |
| KR (1) | KR102654709B1 (enExample) |
| CN (1) | CN107635993B (enExample) |
| AU (1) | AU2016233288A1 (enExample) |
| BR (1) | BR112017019773A2 (enExample) |
| CA (1) | CA2980159A1 (enExample) |
| EA (1) | EA032315B1 (enExample) |
| ES (1) | ES2797805T3 (enExample) |
| IL (1) | IL254424A0 (enExample) |
| MX (1) | MX2017011434A (enExample) |
| SG (1) | SG11201707469WA (enExample) |
| WO (1) | WO2016149436A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112017019731A2 (pt) | 2015-03-18 | 2018-05-22 | Bristol-Myers Squibb Company | compostos heterocíclicos tricíclicos úteis como inibidores de tnf |
| ES2803650T3 (es) | 2015-03-18 | 2021-01-28 | Bristol Myers Squibb Co | Compuestos heterocíclicos útiles como inhibidores de TNF |
| US9879016B2 (en) | 2015-04-17 | 2018-01-30 | Abbvie Inc. | Indazolones as modulators of TNF signaling |
| WO2016168633A1 (en) | 2015-04-17 | 2016-10-20 | Abbvie Inc. | Indazolones as modulators of tnf signaling |
| UY36630A (es) | 2015-04-17 | 2016-11-30 | Abbvie Inc | Moduladores tricíclicos de la señalización por tnf |
| GB201510758D0 (en) | 2015-06-18 | 2015-08-05 | Ucb Biopharma Sprl | Novel TNFa structure for use in therapy |
| EP3331889B1 (en) | 2015-08-03 | 2020-09-23 | Bristol-Myers Squibb Company | Cyclic compounds useful as modulators of tnf alpha |
| GB201621907D0 (en) | 2016-12-21 | 2017-02-01 | Ucb Biopharma Sprl And Sanofi | Antibody epitope |
| EP3596078B1 (en) * | 2017-03-15 | 2023-04-12 | UCB Biopharma SRL | Fused pentacyclic imidazole derivatives as modulators of tnf activity |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6038397B2 (ja) * | 1980-03-06 | 1985-08-31 | エスエス製薬株式会社 | チアジノイミダゾ−ル誘導体及びその製造法 |
| ATE238998T1 (de) | 1997-02-25 | 2003-05-15 | Us Gov Health & Human Serv | Substituierte benzimidazole als nicht-nucleoside reverse transcriptase inhibitore |
| AU7922900A (en) * | 1999-10-27 | 2001-05-08 | Novartis Ag | Thiazole and imidazo (4,5-b) pyridine compounds and their pharmaceutical use |
| US7601846B2 (en) | 2001-06-26 | 2009-10-13 | The Regents Of The University Of California | Compounds having activity as inhibitors of apoptosis |
| EP1479681A4 (en) | 2002-01-31 | 2006-05-10 | Daiichi Seiyaku Co | IMIDAZO (1,2-a) pyridine |
| WO2004050035A2 (en) | 2002-12-03 | 2004-06-17 | Isis Pharmaceuticals, Inc. | Benzimidazoles and analogs thereof as antivirals |
| US20050124638A1 (en) | 2003-12-08 | 2005-06-09 | Swayze Eric E. | Benzimidazoles and analogs thereof as antivirals |
| AU2008267443A1 (en) * | 2007-06-26 | 2008-12-31 | Sanofi-Aventis | A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles |
| FR2919610B1 (fr) * | 2007-08-02 | 2009-10-16 | Sanofi Aventis Sa | Derives de n-heteroaryl-carboxamides tricycliques,leur preparation et leur application en therapeutique |
| WO2009045174A1 (en) | 2007-10-05 | 2009-04-09 | S*Bio Pte Ltd | 2-morpholinylpurines as inhibitors of pi3k |
| JP2009227599A (ja) | 2008-03-21 | 2009-10-08 | Daiichi Sankyo Co Ltd | イミダゾピリダジン誘導体 |
| CN101717397B (zh) | 2008-10-09 | 2012-11-28 | 中国科学院上海药物研究所 | 一类取代吡啶并[2',1':2,3]咪唑并[4,5-c]异喹啉酮类化合物及其合成方法和用途,以及包含该类化合物的药物组合物 |
| ES2443948T3 (es) * | 2008-12-19 | 2014-02-21 | Bristol-Myers Squibb Company | Compuestos de carbazol carboxamida útiles como inhibidores de quinasas |
| US8691187B2 (en) | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
| EP2411057B1 (en) | 2009-03-23 | 2020-05-06 | Eli Lilly and Company | Imaging agents for detecting neurological disorders |
| WO2012148550A1 (en) | 2011-02-25 | 2012-11-01 | Myrexis, Inc. | Prodrugs of therapeutic compounds |
| EP2527344A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases |
| CA2874303C (en) | 2012-06-11 | 2020-10-13 | Ucb Biopharma Sprl | Tnf -alpha modulating benz imidazoles |
| US9309243B2 (en) | 2012-07-13 | 2016-04-12 | Ucb Biopharma Sprl | Imidazopyridine derivatives as modulators of TNF activity |
| GB201212513D0 (en) | 2012-07-13 | 2012-08-29 | Ucb Pharma Sa | Therapeutic agents |
| GB201321743D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| WO2015086519A1 (en) | 2013-12-09 | 2015-06-18 | Ucb Biopharma Sprl | Imidazopyridine derivatives as modulators of tnf activity |
| GB201321738D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic Agents |
| GB201321737D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic Agents |
| GB201321741D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| GB201321746D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| GB201321745D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| GB201321735D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic Agents |
| GB201321742D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| EP3080085B1 (en) | 2013-12-09 | 2019-08-14 | UCB Biopharma SPRL | Fused bicyclic heteroaromatic derivatives as modulators of tnf activity |
| GB201321744D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| GB201321739D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| KR20230035424A (ko) | 2014-10-06 | 2023-03-13 | 시그날 파마소티칼 엘엘씨 | 치환된 아미노퓨린 화합물, 그의 조성물 및 그를 사용한 치료 방법 |
| BR112017019731A2 (pt) | 2015-03-18 | 2018-05-22 | Bristol-Myers Squibb Company | compostos heterocíclicos tricíclicos úteis como inibidores de tnf |
| ES2803650T3 (es) | 2015-03-18 | 2021-01-28 | Bristol Myers Squibb Co | Compuestos heterocíclicos útiles como inhibidores de TNF |
-
2016
- 2016-03-17 ES ES16712645T patent/ES2797805T3/es active Active
- 2016-03-17 SG SG11201707469WA patent/SG11201707469WA/en unknown
- 2016-03-17 EA EA201792034A patent/EA032315B1/ru not_active IP Right Cessation
- 2016-03-17 KR KR1020177029449A patent/KR102654709B1/ko active Active
- 2016-03-17 AU AU2016233288A patent/AU2016233288A1/en not_active Abandoned
- 2016-03-17 CN CN201680026733.XA patent/CN107635993B/zh active Active
- 2016-03-17 CA CA2980159A patent/CA2980159A1/en not_active Abandoned
- 2016-03-17 US US15/558,692 patent/US10189840B2/en active Active
- 2016-03-17 BR BR112017019773-1A patent/BR112017019773A2/pt not_active Application Discontinuation
- 2016-03-17 EP EP16712645.7A patent/EP3271360B1/en active Active
- 2016-03-17 MX MX2017011434A patent/MX2017011434A/es unknown
- 2016-03-17 WO PCT/US2016/022737 patent/WO2016149436A1/en not_active Ceased
- 2016-03-17 JP JP2017549092A patent/JP6793657B2/ja active Active
-
2017
- 2017-09-11 IL IL254424A patent/IL254424A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3271360A1 (en) | 2018-01-24 |
| KR20170129810A (ko) | 2017-11-27 |
| EA201792034A1 (ru) | 2018-03-30 |
| US10189840B2 (en) | 2019-01-29 |
| SG11201707469WA (en) | 2017-10-30 |
| BR112017019773A2 (pt) | 2018-05-15 |
| JP2018508553A (ja) | 2018-03-29 |
| WO2016149436A1 (en) | 2016-09-22 |
| CN107635993A (zh) | 2018-01-26 |
| AU2016233288A1 (en) | 2017-11-09 |
| EA032315B1 (ru) | 2019-05-31 |
| MX2017011434A (es) | 2018-01-25 |
| EP3271360B1 (en) | 2020-04-22 |
| ES2797805T3 (es) | 2020-12-03 |
| KR102654709B1 (ko) | 2024-04-03 |
| US20180111936A1 (en) | 2018-04-26 |
| CA2980159A1 (en) | 2016-09-22 |
| JP6793657B2 (ja) | 2020-12-02 |
| CN107635993B (zh) | 2020-05-22 |
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