IL234701B - Topically administered strontium-containing complexes for treating pain, pruritis and inflammation - Google Patents

Topically administered strontium-containing complexes for treating pain, pruritis and inflammation

Info

Publication number
IL234701B
IL234701B IL234701A IL23470114A IL234701B IL 234701 B IL234701 B IL 234701B IL 234701 A IL234701 A IL 234701A IL 23470114 A IL23470114 A IL 23470114A IL 234701 B IL234701 B IL 234701B
Authority
IL
Israel
Prior art keywords
itching
strontium
inflammation
pain
treatment
Prior art date
Application number
IL234701A
Other languages
English (en)
Hebrew (he)
Other versions
IL234701A0 (en
Inventor
s hahn Gary
Original Assignee
Cosmederm Bioscience Inc
Hahn Gary S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cosmederm Bioscience Inc, Hahn Gary S filed Critical Cosmederm Bioscience Inc
Publication of IL234701A0 publication Critical patent/IL234701A0/en
Publication of IL234701B publication Critical patent/IL234701B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
IL234701A 2012-03-21 2014-09-17 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation IL234701B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261613923P 2012-03-21 2012-03-21
PCT/US2013/032608 WO2013142383A1 (en) 2012-03-21 2013-03-15 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation

Publications (2)

Publication Number Publication Date
IL234701A0 IL234701A0 (en) 2014-11-30
IL234701B true IL234701B (en) 2020-03-31

Family

ID=49223278

Family Applications (1)

Application Number Title Priority Date Filing Date
IL234701A IL234701B (en) 2012-03-21 2014-09-17 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation

Country Status (15)

Country Link
US (5) US9333185B2 (https=)
EP (1) EP2827847B1 (https=)
JP (1) JP6163633B2 (https=)
KR (1) KR101729096B1 (https=)
CN (1) CN104363901B (https=)
AU (1) AU2013235345B2 (https=)
BR (1) BR112014023473B1 (https=)
CA (2) CA3026687A1 (https=)
ES (1) ES2930524T3 (https=)
IL (1) IL234701B (https=)
MX (1) MX351698B (https=)
PH (1) PH12014502093A1 (https=)
RU (1) RU2605279C2 (https=)
SG (1) SG11201405866VA (https=)
WO (1) WO2013142383A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2827847B1 (en) * 2012-03-21 2022-09-14 Galleon Labs LLC Topically administered strontium-containing complexes for treating pain, pruritis and inflammation
WO2016130686A1 (en) * 2015-02-11 2016-08-18 Cosmederm Bioscience, Inc. Stable high concentration strontium compounds and formulations for topical application
WO2016141219A1 (en) * 2015-03-05 2016-09-09 Cosmederm Bioscience, Inc. Strontium based compositions and formulations for pain, pruritus, and inflammation
US11235002B2 (en) 2015-08-21 2022-02-01 Galleon Labs Llc Strontium based compositions and formulations for pain, pruritus, and inflammation
US20170049807A1 (en) * 2015-08-21 2017-02-23 Cosmederm Bioscience, Inc. Strontium based compositions and formulations for pain, pruritus, and inflammation
US20170157169A1 (en) * 2015-08-21 2017-06-08 Cosmederm Bioscience, Inc. Strontium based compositions and formulations for pain, pruritus, and inflammation
KR101651605B1 (ko) * 2015-12-10 2016-08-26 대봉엘에스 주식회사 신규 페놀산류 유도체 화합물, 및 이의 용도
CA2958169C (en) * 2016-08-17 2025-01-07 Galleon Labs Llc Strontium-based compositions and formulations for pain, itching, and inflammation
KR101782966B1 (ko) * 2017-03-14 2017-09-28 전북대학교산학협력단 가려움증의 예방 또는 치료용 조성물
US10559492B2 (en) 2017-11-15 2020-02-11 Taiwan Semiconductor Manufacturing Company, Ltd. Patterning methods for semiconductor devices and structures resulting therefrom
WO2020037114A1 (en) * 2018-08-17 2020-02-20 Galleon Labs Llc Compositions and methods for the modulation of cytokines
WO2020247961A1 (en) * 2019-06-07 2020-12-10 Advanced Delivery Labs Llc Compositions and methods for improving wellness

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US3833732A (en) * 1973-05-24 1974-09-03 Miles Lab Method of treating inflammation utilizing alkyl esters of gallic acid
US4477439A (en) 1981-04-13 1984-10-16 Walter J. Monacelli Treatment of irritated and excoriated areas around the stoma of ostomy patients
GB2180153A (en) 1985-09-10 1987-03-25 Rory Ltd Compositions containing acetylcysteine
US6051609A (en) 1997-09-09 2000-04-18 Tristrata Technology, Inc. Additives enhancing the effect of therapeutic agents
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FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
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US5716625A (en) * 1994-12-21 1998-02-10 Cosmederm Technologies Formulations and methods for reducing skin irritation
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EP0737471A3 (fr) 1995-04-10 2000-12-06 L'oreal Utilisation d'un sel d'une métal alcalino-terreux comme inhibiteur de TNF-alpha dans une composition unique et composition obtenue
FR2740341B1 (fr) 1995-10-26 1997-12-19 Oreal Utilisation de sel de lanthanide, d'etain, de zinc, de manganese, d'yttrium, de cobalt, de baryum, de strontium dans une composition pour la peau
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NO20014746D0 (no) * 2001-09-28 2001-09-28 Clas M Kjoelberg Smertelindrende middel
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US20170049807A1 (en) 2015-08-21 2017-02-23 Cosmederm Bioscience, Inc. Strontium based compositions and formulations for pain, pruritus, and inflammation
US11235002B2 (en) 2015-08-21 2022-02-01 Galleon Labs Llc Strontium based compositions and formulations for pain, pruritus, and inflammation
US20170157169A1 (en) 2015-08-21 2017-06-08 Cosmederm Bioscience, Inc. Strontium based compositions and formulations for pain, pruritus, and inflammation

Also Published As

Publication number Publication date
US20240041919A1 (en) 2024-02-08
BR112014023473A2 (https=) 2017-06-20
CA3026687A1 (en) 2013-09-26
EP2827847A1 (en) 2015-01-28
RU2605279C2 (ru) 2016-12-20
EP2827847B1 (en) 2022-09-14
SG11201405866VA (en) 2014-10-30
MX351698B (es) 2017-10-24
JP2015510943A (ja) 2015-04-13
US10874689B2 (en) 2020-12-29
US10159693B2 (en) 2018-12-25
US20170020918A1 (en) 2017-01-26
PH12014502093A1 (en) 2014-11-24
AU2013235345A1 (en) 2014-10-09
KR101729096B1 (ko) 2017-04-21
HK1204266A1 (en) 2015-11-13
CN104363901A (zh) 2015-02-18
CA2867439A1 (en) 2013-09-26
BR112014023473B1 (pt) 2022-08-30
RU2014142259A (ru) 2016-05-20
US9333185B2 (en) 2016-05-10
US11801261B2 (en) 2023-10-31
US20210177888A1 (en) 2021-06-17
IL234701A0 (en) 2014-11-30
WO2013142383A1 (en) 2013-09-26
JP6163633B2 (ja) 2017-07-19
CA2867439C (en) 2019-02-12
EP2827847A4 (en) 2015-01-28
CN104363901B (zh) 2017-03-22
AU2013235345B2 (en) 2016-03-24
US20150050361A1 (en) 2015-02-19
MX2014011382A (es) 2015-04-17
KR20140138993A (ko) 2014-12-04
ES2930524T3 (es) 2022-12-14
US20190076469A1 (en) 2019-03-14

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