IL227768A - Use of 2-, 4-disulfonyl-α-phenyl butyl tertiary nitron in the preparation of brain injury preparations - Google Patents
Use of 2-, 4-disulfonyl-α-phenyl butyl tertiary nitron in the preparation of brain injury preparationsInfo
- Publication number
- IL227768A IL227768A IL227768A IL22776813A IL227768A IL 227768 A IL227768 A IL 227768A IL 227768 A IL227768 A IL 227768A IL 22776813 A IL22776813 A IL 22776813A IL 227768 A IL227768 A IL 227768A
- Authority
- IL
- Israel
- Prior art keywords
- noise
- brain injury
- exposure
- nac
- composition
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
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- A—HUMAN NECESSITIES
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| US9050305B2 (en) | 2012-03-29 | 2015-06-09 | Chs Pharma, Inc. | Treatment for ischemic stroke |
| WO2014172583A2 (en) * | 2013-04-18 | 2014-10-23 | Jinsheng Zhang | Compositions and methods utilizing phosphodiesterase inhibitors to treat blast-induced tinnitus and/or hearing loss |
| EP3340972A4 (en) * | 2015-09-18 | 2019-05-01 | Oklahoma Medical Research Foundation | METHOD FOR TRANSPORTING AN ACTIVE AGENT THROUGH THE BLOOD BRAIN, BLOOD COCHLEA OR BLOOD LIQUOR BARRIER |
| HUE069280T2 (hu) * | 2016-05-18 | 2025-02-28 | Sound Pharmaceuticals Incorporated | Ebselen a Meniere-kór kezelésére történõ felhasználásra |
| JP2019537582A (ja) * | 2016-10-31 | 2019-12-26 | ハフ イアー インスティテュート | シナプス形成および神経突起形成を増強するための方法 |
| US11020354B2 (en) | 2017-01-19 | 2021-06-01 | Otologic Pharmaceuticals, Inc. | Formulations of n-acetylcysteine and uses thereof |
| US11617731B2 (en) | 2017-04-28 | 2023-04-04 | Axcella Health, Inc. | Amino acid compositions and their use for the treatment of traumatic brain injury |
| CA3072092A1 (en) * | 2017-08-14 | 2019-02-21 | Axcella Health Inc. | Branched-chain amino acids for the treatment of neuronal injury |
| JP7254780B2 (ja) | 2017-09-20 | 2023-04-10 | オクラホマ・メディカル・リサーチ・ファウンデーション | 薬剤耐性神経膠腫の治療法 |
| WO2019084543A1 (en) | 2017-10-27 | 2019-05-02 | Beyond Barriers Therapeutics, Inc. | ENHANCED ANTIOXIDANT ADMINISTRATION FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS INVOLVING OXIDATIVE STRESS |
| WO2019213245A1 (en) * | 2018-05-03 | 2019-11-07 | Hough Ear Institute | Methods for reducing accumulated pathologic tau protein |
| US20210369147A1 (en) * | 2018-07-18 | 2021-12-02 | The Regents Of The University Of California | Multimodal Neuroimaging-Based Diagnostic Systems and Methods for Detecting Tinnitus |
| WO2020023755A1 (en) * | 2018-07-26 | 2020-01-30 | CHS Pharma Inc. | Treatment for ischemic stroke |
| WO2020056056A1 (en) * | 2018-09-12 | 2020-03-19 | Hough Ear Institute | Methods for treating hearing loss incident to cochlear implant surgery |
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| US5488145A (en) * | 1993-12-23 | 1996-01-30 | Oklahoma Medical Research Foundation | 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps |
| WO2000027376A2 (de) | 1998-10-26 | 2000-05-18 | Michael Schedler | Verwendung von thiolverbindungen, oxidoreduktasen und/oder hydrolasen zur behandlung des tinnitus, insbesondere des chronischen tinnitus |
| AU1574701A (en) | 1999-10-22 | 2001-04-30 | Wrair Walter Reed Army Institute Of Research | A pharmaceutical composition containing pglu-glu-pro-nh2 and method for treating diseases and injuries to the brain, spinal cord and retina using same |
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| US6428474B1 (en) | 2000-05-24 | 2002-08-06 | Sol Weiss | Surgical instrument |
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| US7550439B2 (en) | 2004-01-23 | 2009-06-23 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
| CA2606053A1 (en) | 2005-04-21 | 2006-11-02 | Glenn Goldstein | N-acetylcysteine amide (nac amide) for the treatment of diseases and conditions associated with oxidative stress |
| ATE480191T1 (de) | 2006-06-29 | 2010-09-15 | L R S Ortho Ltd | System zur lokalisation von distalen löchern eines marknagels |
| EP2054047B1 (en) * | 2006-07-25 | 2014-12-17 | Hough Ear Institute | Methods for treating acute acoustic trauma |
| US8784870B2 (en) * | 2008-07-21 | 2014-07-22 | Otonomy, Inc. | Controlled release compositions for modulating free-radical induced damage and methods of use thereof |
| US9289462B2 (en) | 2008-09-17 | 2016-03-22 | Terry Gage | Method for medical treatment utilizing glutathione |
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