ES2893825T3 - Métodos de tratamiento de lesiones cerebrales - Google Patents
Métodos de tratamiento de lesiones cerebrales Download PDFInfo
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- ES2893825T3 ES2893825T3 ES12742491T ES12742491T ES2893825T3 ES 2893825 T3 ES2893825 T3 ES 2893825T3 ES 12742491 T ES12742491 T ES 12742491T ES 12742491 T ES12742491 T ES 12742491T ES 2893825 T3 ES2893825 T3 ES 2893825T3
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
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- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161439671P | 2011-02-04 | 2011-02-04 | |
| PCT/US2012/023855 WO2012106654A1 (en) | 2011-02-04 | 2012-02-03 | Methods for treating brain injury |
Publications (1)
| Publication Number | Publication Date |
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| ES2893825T3 true ES2893825T3 (es) | 2022-02-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ES12742491T Active ES2893825T3 (es) | 2011-02-04 | 2012-02-03 | Métodos de tratamiento de lesiones cerebrales |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US9289404B2 (enExample) |
| EP (1) | EP2670403B1 (enExample) |
| JP (2) | JP6099574B2 (enExample) |
| AU (1) | AU2012211989B2 (enExample) |
| CA (1) | CA2826602C (enExample) |
| ES (1) | ES2893825T3 (enExample) |
| IL (2) | IL227768A (enExample) |
| WO (1) | WO2012106654A1 (enExample) |
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| US9050305B2 (en) | 2012-03-29 | 2015-06-09 | Chs Pharma, Inc. | Treatment for ischemic stroke |
| WO2014172583A2 (en) * | 2013-04-18 | 2014-10-23 | Jinsheng Zhang | Compositions and methods utilizing phosphodiesterase inhibitors to treat blast-induced tinnitus and/or hearing loss |
| EP3340972A4 (en) * | 2015-09-18 | 2019-05-01 | Oklahoma Medical Research Foundation | METHOD FOR TRANSPORTING AN ACTIVE AGENT THROUGH THE BLOOD BRAIN, BLOOD COCHLEA OR BLOOD LIQUOR BARRIER |
| HUE069280T2 (hu) * | 2016-05-18 | 2025-02-28 | Sound Pharmaceuticals Incorporated | Ebselen a Meniere-kór kezelésére történõ felhasználásra |
| JP2019537582A (ja) * | 2016-10-31 | 2019-12-26 | ハフ イアー インスティテュート | シナプス形成および神経突起形成を増強するための方法 |
| EP3570826A4 (en) * | 2017-01-19 | 2020-09-23 | Otologic Pharmaceutics, Inc. | N-ACETYLCYSTEIN FORMULATIONS AND THEIR USES |
| US11617731B2 (en) | 2017-04-28 | 2023-04-04 | Axcella Health, Inc. | Amino acid compositions and their use for the treatment of traumatic brain injury |
| JP7370960B2 (ja) * | 2017-08-14 | 2023-10-30 | アクセラ・ヘルス・インコーポレイテッド | 神経細胞損傷の治療のためのアミノ酸組成物 |
| US11660280B2 (en) | 2017-09-20 | 2023-05-30 | Oklahoma Medical Research Foundation | Treatment of drug resistant gliomas |
| EP3700525A4 (en) | 2017-10-27 | 2021-08-25 | Beyond Barriers Therapeutics, Inc. | IMPROVED PROVISION OF ANTIOXIDANTS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES WITH OXIDATIVE STRESS |
| WO2019213245A1 (en) * | 2018-05-03 | 2019-11-07 | Hough Ear Institute | Methods for reducing accumulated pathologic tau protein |
| US20210369147A1 (en) * | 2018-07-18 | 2021-12-02 | The Regents Of The University Of California | Multimodal Neuroimaging-Based Diagnostic Systems and Methods for Detecting Tinnitus |
| WO2020023755A1 (en) | 2018-07-26 | 2020-01-30 | CHS Pharma Inc. | Treatment for ischemic stroke |
| KR102899320B1 (ko) * | 2018-09-12 | 2025-12-12 | 호 이어 인스티튜트 | 인공 와우 수술에 따른 난청의 치료 방법 |
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| US5488145A (en) | 1993-12-23 | 1996-01-30 | Oklahoma Medical Research Foundation | 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps |
| WO2000027376A2 (de) | 1998-10-26 | 2000-05-18 | Michael Schedler | Verwendung von thiolverbindungen, oxidoreduktasen und/oder hydrolasen zur behandlung des tinnitus, insbesondere des chronischen tinnitus |
| AU1574701A (en) | 1999-10-22 | 2001-04-30 | Wrair Walter Reed Army Institute Of Research | A pharmaceutical composition containing pglu-glu-pro-nh2 and method for treating diseases and injuries to the brain, spinal cord and retina using same |
| SE0001916D0 (sv) | 2000-05-23 | 2000-05-23 | Astrazeneca Ab | Novel formulation |
| US6428474B1 (en) | 2000-05-24 | 2002-08-06 | Sol Weiss | Surgical instrument |
| US7115666B2 (en) | 2002-10-15 | 2006-10-03 | Renovis, Inc. | Nitrone compounds, pharmaceutical compositions containing the same and methods for treating inflammation and neuropathic pain |
| RU2376028C2 (ru) | 2004-01-23 | 2009-12-20 | Корнелл Рисеч Фаундейшн, Инк. | Способ уменьшения окислительного повреждения (варианты) |
| EP1877044A4 (en) | 2005-04-21 | 2009-09-02 | Glenn A Goldstein | AMIDE N-ACETYLCYSTEINE (AMIDE NAC) FOR THE TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH OXIDATIVE STRESS |
| US8231629B2 (en) | 2006-06-29 | 2012-07-31 | L.R.S. Ortho Ltd. | System and method for locating of distal holes of an intramedullary nail |
| WO2008013866A2 (en) * | 2006-07-25 | 2008-01-31 | Hough Ear Institute | Methods for treating acute acoustic trauma |
| US8784870B2 (en) * | 2008-07-21 | 2014-07-22 | Otonomy, Inc. | Controlled release compositions for modulating free-radical induced damage and methods of use thereof |
| US9289462B2 (en) * | 2008-09-17 | 2016-03-22 | Terry Gage | Method for medical treatment utilizing glutathione |
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Also Published As
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| EP2670403A1 (en) | 2013-12-11 |
| AU2012211989B2 (en) | 2017-03-02 |
| CA2826602C (en) | 2019-06-11 |
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| IL247911A0 (en) | 2016-11-30 |
| US9642823B2 (en) | 2017-05-09 |
| IL227768A0 (en) | 2013-09-30 |
| JP2014511374A (ja) | 2014-05-15 |
| US9289404B2 (en) | 2016-03-22 |
| US20170281583A1 (en) | 2017-10-05 |
| US20160158173A1 (en) | 2016-06-09 |
| JP6286589B2 (ja) | 2018-02-28 |
| CA2826602A1 (en) | 2012-08-09 |
| JP6099574B2 (ja) | 2017-03-22 |
| EP2670403A4 (en) | 2014-07-09 |
| IL227768A (en) | 2016-10-31 |
| IL247911B (en) | 2021-05-31 |
| US20170202797A1 (en) | 2017-07-20 |
| US20140187631A1 (en) | 2014-07-03 |
| WO2012106654A1 (en) | 2012-08-09 |
| US10022346B2 (en) | 2018-07-17 |
| EP2670403B1 (en) | 2021-08-18 |
| AU2012211989A1 (en) | 2013-08-22 |
| US10111843B2 (en) | 2018-10-30 |
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