IL226173A - Dodtsil 2 - (n, n - dimethylamino) active enantiomer - propionate - Google Patents
Dodtsil 2 - (n, n - dimethylamino) active enantiomer - propionateInfo
- Publication number
- IL226173A IL226173A IL226173A IL22617313A IL226173A IL 226173 A IL226173 A IL 226173A IL 226173 A IL226173 A IL 226173A IL 22617313 A IL22617313 A IL 22617313A IL 226173 A IL226173 A IL 226173A
- Authority
- IL
- Israel
- Prior art keywords
- dimethylamino
- propionate
- dodecyl
- active enantiomer
- enantiomer
- Prior art date
Links
- HSMMSDWNEJLVRY-INIZCTEOSA-N dodecyl (2s)-2-(dimethylamino)propanoate Chemical compound CCCCCCCCCCCCOC(=O)[C@H](C)N(C)C HSMMSDWNEJLVRY-INIZCTEOSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41899610P | 2010-12-02 | 2010-12-02 | |
| PCT/US2011/062579 WO2012075107A2 (en) | 2010-12-02 | 2011-11-30 | Active enantiomer of dodecyl 2-(n,n-dimethylamino)-propionate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL226173A0 IL226173A0 (en) | 2013-07-31 |
| IL226173A true IL226173A (en) | 2016-10-31 |
Family
ID=46172526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL226173A IL226173A (en) | 2010-12-02 | 2013-05-05 | Dodtsil 2 - (n, n - dimethylamino) active enantiomer - propionate |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20130267562A1 (enExample) |
| EP (1) | EP2646015B1 (enExample) |
| JP (1) | JP6109075B2 (enExample) |
| KR (1) | KR102004552B1 (enExample) |
| CN (1) | CN103930105B (enExample) |
| AU (2) | AU2011336692B2 (enExample) |
| BR (1) | BR112013012799A8 (enExample) |
| CA (1) | CA2817417C (enExample) |
| CL (1) | CL2013001391A1 (enExample) |
| CR (1) | CR20130324A (enExample) |
| ES (1) | ES2801999T3 (enExample) |
| IL (1) | IL226173A (enExample) |
| MX (1) | MX2013005522A (enExample) |
| NZ (1) | NZ609826A (enExample) |
| PH (1) | PH12013501104A1 (enExample) |
| PL (1) | PL2646015T3 (enExample) |
| RU (1) | RU2679308C2 (enExample) |
| SG (2) | SG10201803321TA (enExample) |
| WO (1) | WO2012075107A2 (enExample) |
| ZA (1) | ZA201304840B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014028780A2 (en) * | 2012-08-15 | 2014-02-20 | Nexmed Holdings, Inc. | Antifungal compounds and methods of use |
| US8900625B2 (en) | 2012-12-15 | 2014-12-02 | Nexmed Holdings, Inc. | Antimicrobial compounds and methods of use |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6118020A (en) * | 1999-05-19 | 2000-09-12 | Nexmed Holdings, Inc. | Crystalline salts of dodecyl 2-(N,N-dimethylamino)-propionate |
| US6323241B1 (en) * | 2000-01-10 | 2001-11-27 | Nexmed (Holdings) Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
| DE10033853A1 (de) * | 2000-07-12 | 2002-01-31 | Hexal Ag | Transdermales therapeutisches System mit hochdispersem Siliziumdioxid |
| JP5160018B2 (ja) * | 2002-06-25 | 2013-03-13 | アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド | 非晶質医薬組成物を用いる経皮送達速度調節 |
| US20050181030A1 (en) * | 2003-01-03 | 2005-08-18 | Mo Y. J. | Topical stabilized prostaglandin E compound dosage forms |
| EP1635770B1 (en) * | 2003-03-21 | 2009-05-27 | Nexmed Holdings, Inc. | Antifungal nail coat and method of use |
| WO2005009510A2 (en) * | 2003-07-23 | 2005-02-03 | The Regents Of The University Of California | Penetration enhancer combinations for transdermal delivery |
| PL1670433T3 (pl) * | 2003-10-10 | 2013-03-29 | Ferring Bv | Przezskórna formulacja farmaceutyczna do zmniejszania pozostałości na skórze |
| WO2005051960A2 (en) * | 2003-11-22 | 2005-06-09 | Midwest Research Laboratories, Llc | Hydrocarbyl aminohydrocarbonoates and aminohydrocarbonol hydrocarbonoates as antimicrobial and antiviral agents |
| RU2012153177A (ru) * | 2010-05-04 | 2014-06-20 | Нексмед Холдингс, Инк. | Композиции низкомолекулярных терапевтических средств |
| US8900625B2 (en) * | 2012-12-15 | 2014-12-02 | Nexmed Holdings, Inc. | Antimicrobial compounds and methods of use |
-
2011
- 2011-11-30 NZ NZ609826A patent/NZ609826A/en not_active IP Right Cessation
- 2011-11-30 KR KR1020137013227A patent/KR102004552B1/ko not_active Expired - Fee Related
- 2011-11-30 MX MX2013005522A patent/MX2013005522A/es unknown
- 2011-11-30 JP JP2013542128A patent/JP6109075B2/ja not_active Expired - Fee Related
- 2011-11-30 PL PL11845087T patent/PL2646015T3/pl unknown
- 2011-11-30 PH PH1/2013/501104A patent/PH12013501104A1/en unknown
- 2011-11-30 US US13/991,111 patent/US20130267562A1/en not_active Abandoned
- 2011-11-30 EP EP11845087.3A patent/EP2646015B1/en active Active
- 2011-11-30 CA CA2817417A patent/CA2817417C/en not_active Expired - Fee Related
- 2011-11-30 AU AU2011336692A patent/AU2011336692B2/en not_active Ceased
- 2011-11-30 WO PCT/US2011/062579 patent/WO2012075107A2/en not_active Ceased
- 2011-11-30 SG SG10201803321TA patent/SG10201803321TA/en unknown
- 2011-11-30 SG SG2013035258A patent/SG190199A1/en unknown
- 2011-11-30 ES ES11845087T patent/ES2801999T3/es active Active
- 2011-11-30 CN CN201180054224.5A patent/CN103930105B/zh not_active Expired - Fee Related
- 2011-11-30 RU RU2013119439A patent/RU2679308C2/ru not_active Application Discontinuation
- 2011-11-30 BR BR112013012799A patent/BR112013012799A8/pt not_active Application Discontinuation
-
2013
- 2013-05-05 IL IL226173A patent/IL226173A/en active IP Right Grant
- 2013-05-16 CL CL2013001391A patent/CL2013001391A1/es unknown
- 2013-06-26 CR CR20130324A patent/CR20130324A/es unknown
- 2013-06-28 ZA ZA2013/04840A patent/ZA201304840B/en unknown
-
2017
- 2017-01-17 AU AU2017200314A patent/AU2017200314A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| SG10201803321TA (en) | 2018-06-28 |
| ES2801999T3 (es) | 2021-01-15 |
| BR112013012799A8 (pt) | 2018-01-09 |
| CN103930105A (zh) | 2014-07-16 |
| AU2011336692B2 (en) | 2017-02-16 |
| KR20140023875A (ko) | 2014-02-27 |
| AU2017200314A1 (en) | 2017-02-02 |
| MX2013005522A (es) | 2013-07-17 |
| CA2817417C (en) | 2020-12-29 |
| SG190199A1 (en) | 2013-06-28 |
| CL2013001391A1 (es) | 2013-11-08 |
| US20130267562A1 (en) | 2013-10-10 |
| KR102004552B1 (ko) | 2019-10-01 |
| PL2646015T3 (pl) | 2020-11-30 |
| EP2646015A2 (en) | 2013-10-09 |
| RU2679308C2 (ru) | 2019-02-07 |
| CR20130324A (es) | 2013-08-13 |
| BR112013012799A2 (pt) | 2016-09-13 |
| WO2012075107A2 (en) | 2012-06-07 |
| CN103930105B (zh) | 2019-11-01 |
| WO2012075107A3 (en) | 2014-03-06 |
| RU2013119439A (ru) | 2015-01-10 |
| JP6109075B2 (ja) | 2017-04-05 |
| NZ609826A (en) | 2016-03-31 |
| JP2014514243A (ja) | 2014-06-19 |
| ZA201304840B (en) | 2014-04-30 |
| EP2646015A4 (en) | 2015-04-08 |
| EP2646015B1 (en) | 2020-04-22 |
| AU2011336692A1 (en) | 2013-05-30 |
| IL226173A0 (en) | 2013-07-31 |
| PH12013501104A1 (en) | 2013-07-08 |
| CA2817417A1 (en) | 2012-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |