BR112013012799A8 - formulário de dosagem, método de facilitação do transporte de um composto farmaceuticamente ativo através de uma membrana biológica ou tecido e composto farmaceuticamente ativo - Google Patents
formulário de dosagem, método de facilitação do transporte de um composto farmaceuticamente ativo através de uma membrana biológica ou tecido e composto farmaceuticamente ativoInfo
- Publication number
- BR112013012799A8 BR112013012799A8 BR112013012799A BR112013012799A BR112013012799A8 BR 112013012799 A8 BR112013012799 A8 BR 112013012799A8 BR 112013012799 A BR112013012799 A BR 112013012799A BR 112013012799 A BR112013012799 A BR 112013012799A BR 112013012799 A8 BR112013012799 A8 BR 112013012799A8
- Authority
- BR
- Brazil
- Prior art keywords
- active compound
- pharmaceutically active
- facilitating
- tissue
- transport
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 239000002552 dosage form Substances 0.000 title 1
- 239000012528 membrane Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41899610P | 2010-12-02 | 2010-12-02 | |
| PCT/US2011/062579 WO2012075107A2 (en) | 2010-12-02 | 2011-11-30 | Active enantiomer of dodecyl 2-(n,n-dimethylamino)-propionate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013012799A2 BR112013012799A2 (pt) | 2016-09-13 |
| BR112013012799A8 true BR112013012799A8 (pt) | 2018-01-09 |
Family
ID=46172526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013012799A BR112013012799A8 (pt) | 2010-12-02 | 2011-11-30 | formulário de dosagem, método de facilitação do transporte de um composto farmaceuticamente ativo através de uma membrana biológica ou tecido e composto farmaceuticamente ativo |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20130267562A1 (enExample) |
| EP (1) | EP2646015B1 (enExample) |
| JP (1) | JP6109075B2 (enExample) |
| KR (1) | KR102004552B1 (enExample) |
| CN (1) | CN103930105B (enExample) |
| AU (2) | AU2011336692B2 (enExample) |
| BR (1) | BR112013012799A8 (enExample) |
| CA (1) | CA2817417C (enExample) |
| CL (1) | CL2013001391A1 (enExample) |
| CR (1) | CR20130324A (enExample) |
| ES (1) | ES2801999T3 (enExample) |
| IL (1) | IL226173A (enExample) |
| MX (1) | MX2013005522A (enExample) |
| NZ (1) | NZ609826A (enExample) |
| PH (1) | PH12013501104A1 (enExample) |
| PL (1) | PL2646015T3 (enExample) |
| RU (1) | RU2679308C2 (enExample) |
| SG (2) | SG10201803321TA (enExample) |
| WO (1) | WO2012075107A2 (enExample) |
| ZA (1) | ZA201304840B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014028780A2 (en) * | 2012-08-15 | 2014-02-20 | Nexmed Holdings, Inc. | Antifungal compounds and methods of use |
| US8900625B2 (en) | 2012-12-15 | 2014-12-02 | Nexmed Holdings, Inc. | Antimicrobial compounds and methods of use |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6118020A (en) * | 1999-05-19 | 2000-09-12 | Nexmed Holdings, Inc. | Crystalline salts of dodecyl 2-(N,N-dimethylamino)-propionate |
| US6323241B1 (en) * | 2000-01-10 | 2001-11-27 | Nexmed (Holdings) Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
| DE10033853A1 (de) * | 2000-07-12 | 2002-01-31 | Hexal Ag | Transdermales therapeutisches System mit hochdispersem Siliziumdioxid |
| KR20050045946A (ko) * | 2002-06-25 | 2005-05-17 | 애크럭스 디디에스 피티와이 리미티드 | 비정질 약학적 조성물을 이용한 경피전달속도의 제어 |
| US20050181030A1 (en) * | 2003-01-03 | 2005-08-18 | Mo Y. J. | Topical stabilized prostaglandin E compound dosage forms |
| HRP20050918A2 (en) * | 2003-03-21 | 2006-12-31 | Nexmed Holdings | Antifungal nail coat and method of use |
| WO2005009510A2 (en) * | 2003-07-23 | 2005-02-03 | The Regents Of The University Of California | Penetration enhancer combinations for transdermal delivery |
| PT1670433E (pt) * | 2003-10-10 | 2012-02-08 | Ferring Bv | Fórmula farmacológica transdérmica para a minimização de resíduos na pele |
| WO2005051960A2 (en) * | 2003-11-22 | 2005-06-09 | Midwest Research Laboratories, Llc | Hydrocarbyl aminohydrocarbonoates and aminohydrocarbonol hydrocarbonoates as antimicrobial and antiviral agents |
| SG186299A1 (en) * | 2010-05-04 | 2013-01-30 | Nexmed Holdings Inc | Compositions of small molecule therapeutics |
| US8900625B2 (en) * | 2012-12-15 | 2014-12-02 | Nexmed Holdings, Inc. | Antimicrobial compounds and methods of use |
-
2011
- 2011-11-30 SG SG10201803321TA patent/SG10201803321TA/en unknown
- 2011-11-30 WO PCT/US2011/062579 patent/WO2012075107A2/en not_active Ceased
- 2011-11-30 KR KR1020137013227A patent/KR102004552B1/ko not_active Expired - Fee Related
- 2011-11-30 JP JP2013542128A patent/JP6109075B2/ja not_active Expired - Fee Related
- 2011-11-30 CN CN201180054224.5A patent/CN103930105B/zh not_active Expired - Fee Related
- 2011-11-30 PL PL11845087T patent/PL2646015T3/pl unknown
- 2011-11-30 RU RU2013119439A patent/RU2679308C2/ru not_active Application Discontinuation
- 2011-11-30 CA CA2817417A patent/CA2817417C/en not_active Expired - Fee Related
- 2011-11-30 NZ NZ609826A patent/NZ609826A/en not_active IP Right Cessation
- 2011-11-30 PH PH1/2013/501104A patent/PH12013501104A1/en unknown
- 2011-11-30 SG SG2013035258A patent/SG190199A1/en unknown
- 2011-11-30 AU AU2011336692A patent/AU2011336692B2/en not_active Ceased
- 2011-11-30 US US13/991,111 patent/US20130267562A1/en not_active Abandoned
- 2011-11-30 ES ES11845087T patent/ES2801999T3/es active Active
- 2011-11-30 EP EP11845087.3A patent/EP2646015B1/en active Active
- 2011-11-30 BR BR112013012799A patent/BR112013012799A8/pt not_active Application Discontinuation
- 2011-11-30 MX MX2013005522A patent/MX2013005522A/es unknown
-
2013
- 2013-05-05 IL IL226173A patent/IL226173A/en active IP Right Grant
- 2013-05-16 CL CL2013001391A patent/CL2013001391A1/es unknown
- 2013-06-26 CR CR20130324A patent/CR20130324A/es unknown
- 2013-06-28 ZA ZA2013/04840A patent/ZA201304840B/en unknown
-
2017
- 2017-01-17 AU AU2017200314A patent/AU2017200314A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2646015A4 (en) | 2015-04-08 |
| SG10201803321TA (en) | 2018-06-28 |
| NZ609826A (en) | 2016-03-31 |
| IL226173A (en) | 2016-10-31 |
| WO2012075107A3 (en) | 2014-03-06 |
| ES2801999T3 (es) | 2021-01-15 |
| PL2646015T3 (pl) | 2020-11-30 |
| EP2646015B1 (en) | 2020-04-22 |
| AU2011336692B2 (en) | 2017-02-16 |
| BR112013012799A2 (pt) | 2016-09-13 |
| CL2013001391A1 (es) | 2013-11-08 |
| CA2817417A1 (en) | 2012-06-07 |
| JP6109075B2 (ja) | 2017-04-05 |
| SG190199A1 (en) | 2013-06-28 |
| MX2013005522A (es) | 2013-07-17 |
| RU2679308C2 (ru) | 2019-02-07 |
| AU2017200314A1 (en) | 2017-02-02 |
| IL226173A0 (en) | 2013-07-31 |
| CN103930105B (zh) | 2019-11-01 |
| CR20130324A (es) | 2013-08-13 |
| AU2011336692A1 (en) | 2013-05-30 |
| ZA201304840B (en) | 2014-04-30 |
| JP2014514243A (ja) | 2014-06-19 |
| EP2646015A2 (en) | 2013-10-09 |
| CA2817417C (en) | 2020-12-29 |
| WO2012075107A2 (en) | 2012-06-07 |
| PH12013501104A1 (en) | 2013-07-08 |
| KR20140023875A (ko) | 2014-02-27 |
| KR102004552B1 (ko) | 2019-10-01 |
| US20130267562A1 (en) | 2013-10-10 |
| RU2013119439A (ru) | 2015-01-10 |
| CN103930105A (zh) | 2014-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |