IL224694B - A method for producing an enriched library - Google Patents

A method for producing an enriched library

Info

Publication number
IL224694B
IL224694B IL224694A IL22469413A IL224694B IL 224694 B IL224694 B IL 224694B IL 224694 A IL224694 A IL 224694A IL 22469413 A IL22469413 A IL 22469413A IL 224694 B IL224694 B IL 224694B
Authority
IL
Israel
Prior art keywords
making
enriched library
enriched
library
Prior art date
Application number
IL224694A
Other languages
English (en)
Hebrew (he)
Other versions
IL224694A0 (en
Original Assignee
Vipergen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vipergen filed Critical Vipergen
Publication of IL224694A0 publication Critical patent/IL224694A0/en
Publication of IL224694B publication Critical patent/IL224694B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1075Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1068Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL224694A 2010-09-27 2013-02-13 A method for producing an enriched library IL224694B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10180435 2010-09-27
PCT/EP2011/065117 WO2012041633A1 (en) 2010-09-27 2011-09-01 A method for making an enriched library

Publications (2)

Publication Number Publication Date
IL224694A0 IL224694A0 (en) 2013-07-31
IL224694B true IL224694B (en) 2018-08-30

Family

ID=43629282

Family Applications (1)

Application Number Title Priority Date Filing Date
IL224694A IL224694B (en) 2010-09-27 2013-02-13 A method for producing an enriched library

Country Status (8)

Country Link
US (2) US20130288929A1 (https=)
EP (2) EP3399035B1 (https=)
JP (2) JP6193761B2 (https=)
CN (1) CN103119165B (https=)
CA (1) CA2808656C (https=)
DK (2) DK3399035T3 (https=)
IL (1) IL224694B (https=)
WO (1) WO2012041633A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012041633A1 (en) * 2010-09-27 2012-04-05 Vipergen A method for making an enriched library
WO2014088830A2 (en) * 2012-12-05 2014-06-12 The Regents Of The University Of California Screening of nucleic acid agents via particle display
CN104630202A (zh) * 2013-11-13 2015-05-20 北京大学 一种能够减小微量核酸物质整体扩增时产生偏倚的扩增方法
GB201420852D0 (en) * 2014-11-24 2015-01-07 Genevillage Kft Method
WO2017031378A1 (en) * 2015-08-18 2017-02-23 Krusemark Casey J Systems and methods for proteomic activity analysis using dna-encoded probes
AU2017259794B2 (en) 2016-05-02 2023-04-13 Encodia, Inc. Macromolecule analysis employing nucleic acid encoding
US11186836B2 (en) 2016-06-16 2021-11-30 Haystack Sciences Corporation Oligonucleotide directed and recorded combinatorial synthesis of encoded probe molecules
EP3619340A4 (en) 2017-05-02 2021-01-20 Haystack Sciences Corporation OLIGONUCLEOTID-DRIVEN COMBINATORY SYNTHESIS VERIFICATION MOLECULES AND ASSOCIATED MANUFACTURING AND USE PROCESSES
MX2020004559A (es) 2017-10-31 2020-10-05 Encodia Inc Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
RU2020112854A (ru) 2017-11-30 2021-12-30 Арракис Терапьютикс, Инк. Фотозонды, связывающие нуклеиновые кислоты, и способы их применения
EP3914704B9 (en) * 2019-01-22 2023-10-04 Vipergen APS A method for screening of an in vitro display library within a cell
EP3963070A4 (en) 2019-04-30 2023-02-22 Encodia, Inc. METHODS OF PREPARATION OF ANALYTES AND RELATED KITS
CN112941634B (zh) * 2019-12-10 2023-09-26 成都先导药物开发股份有限公司 通过dna编码化合物库筛选同时结合多个生物靶标的化合物的方法
US20240209350A1 (en) * 2021-04-26 2024-06-27 European Molecular Biology Laboratory High complexity microcompartment-based interaction screening
GB202317973D0 (en) 2023-11-24 2024-01-10 Nuclera Ltd Use of DNA encoded libraries

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
EP1123305A1 (en) 1998-10-19 2001-08-16 The Board Of Trustees Of The Leland Stanford Junior University Dna-templated combinatorial library chemistry
EP1423400B2 (en) 2001-03-19 2013-05-22 President and Fellows of Harvard College Evolving new molecular function
ATE371026T1 (de) 2001-06-20 2007-09-15 Nuevolution As Eine methode zur synthese von matrizenabhängigen molekülen
EP1670939B1 (en) * 2003-09-18 2009-11-04 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
CN1898257B (zh) * 2003-12-17 2010-06-23 普雷西斯药品公司 合成编码文库的方法
US7968287B2 (en) * 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
WO2006047791A2 (en) * 2004-10-27 2006-05-04 The Board Of Trustees Of The Leland Stanford Junior University Dna-templated combinatorial library device and method for use
DK1809743T3 (da) * 2004-11-08 2009-05-04 Vipergen Aps Strukturel nukleinsyre-styret kemisk syntese
EP1828381B1 (en) 2004-11-22 2009-01-07 Peter Birk Rasmussen Template directed split and mix systhesis of small molecule libraries
WO2008103900A2 (en) 2007-02-23 2008-08-28 New England Biolabs, Inc. Selection and enrichment of proteins using in vitro compartmentalization
CA2704226A1 (en) * 2007-11-01 2009-05-07 The Arizona Board Of Regents On Behalf Of The University Of Arizona Cell-free methods for detecting protein-ligand interctions
US8153446B2 (en) 2008-05-23 2012-04-10 Kent State University Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems
EP2452195A4 (en) * 2009-07-07 2012-12-05 Agency Science Tech & Res METHODS OF IDENTIFYING A PAIR OF LIAISON PARTNERS
WO2012041633A1 (en) * 2010-09-27 2012-04-05 Vipergen A method for making an enriched library

Also Published As

Publication number Publication date
EP2622073B1 (en) 2018-04-18
JP2013540440A (ja) 2013-11-07
JP6193761B2 (ja) 2017-09-06
WO2012041633A1 (en) 2012-04-05
CA2808656A1 (en) 2012-04-05
DK3399035T3 (da) 2021-05-17
JP2017060513A (ja) 2017-03-30
US20130288929A1 (en) 2013-10-31
EP3399035A1 (en) 2018-11-07
IL224694A0 (en) 2013-07-31
CN103119165A (zh) 2013-05-22
CN103119165B (zh) 2017-04-12
US20170233726A1 (en) 2017-08-17
EP3399035B1 (en) 2021-02-17
DK2622073T3 (da) 2018-07-30
US10513700B2 (en) 2019-12-24
CA2808656C (en) 2019-12-03
DK2622073T5 (en) 2019-02-25
EP2622073A1 (en) 2013-08-07

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