CA2808656C - A method for making an enriched library - Google Patents
A method for making an enriched library Download PDFInfo
- Publication number
- CA2808656C CA2808656C CA2808656A CA2808656A CA2808656C CA 2808656 C CA2808656 C CA 2808656C CA 2808656 A CA2808656 A CA 2808656A CA 2808656 A CA2808656 A CA 2808656A CA 2808656 C CA2808656 C CA 2808656C
- Authority
- CA
- Canada
- Prior art keywords
- binding
- nucleic acid
- target
- dna
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10180435 | 2010-09-27 | ||
| EP10180435.9 | 2010-09-27 | ||
| PCT/EP2011/065117 WO2012041633A1 (en) | 2010-09-27 | 2011-09-01 | A method for making an enriched library |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2808656A1 CA2808656A1 (en) | 2012-04-05 |
| CA2808656C true CA2808656C (en) | 2019-12-03 |
Family
ID=43629282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2808656A Active CA2808656C (en) | 2010-09-27 | 2011-09-01 | A method for making an enriched library |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20130288929A1 (https=) |
| EP (2) | EP3399035B1 (https=) |
| JP (2) | JP6193761B2 (https=) |
| CN (1) | CN103119165B (https=) |
| CA (1) | CA2808656C (https=) |
| DK (2) | DK3399035T3 (https=) |
| IL (1) | IL224694B (https=) |
| WO (1) | WO2012041633A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012041633A1 (en) * | 2010-09-27 | 2012-04-05 | Vipergen | A method for making an enriched library |
| WO2014088830A2 (en) * | 2012-12-05 | 2014-06-12 | The Regents Of The University Of California | Screening of nucleic acid agents via particle display |
| CN104630202A (zh) * | 2013-11-13 | 2015-05-20 | 北京大学 | 一种能够减小微量核酸物质整体扩增时产生偏倚的扩增方法 |
| GB201420852D0 (en) * | 2014-11-24 | 2015-01-07 | Genevillage Kft | Method |
| WO2017031378A1 (en) * | 2015-08-18 | 2017-02-23 | Krusemark Casey J | Systems and methods for proteomic activity analysis using dna-encoded probes |
| AU2017259794B2 (en) | 2016-05-02 | 2023-04-13 | Encodia, Inc. | Macromolecule analysis employing nucleic acid encoding |
| US11186836B2 (en) | 2016-06-16 | 2021-11-30 | Haystack Sciences Corporation | Oligonucleotide directed and recorded combinatorial synthesis of encoded probe molecules |
| EP3619340A4 (en) | 2017-05-02 | 2021-01-20 | Haystack Sciences Corporation | OLIGONUCLEOTID-DRIVEN COMBINATORY SYNTHESIS VERIFICATION MOLECULES AND ASSOCIATED MANUFACTURING AND USE PROCESSES |
| MX2020004559A (es) | 2017-10-31 | 2020-10-05 | Encodia Inc | Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico. |
| RU2020112854A (ru) | 2017-11-30 | 2021-12-30 | Арракис Терапьютикс, Инк. | Фотозонды, связывающие нуклеиновые кислоты, и способы их применения |
| EP3914704B9 (en) * | 2019-01-22 | 2023-10-04 | Vipergen APS | A method for screening of an in vitro display library within a cell |
| EP3963070A4 (en) | 2019-04-30 | 2023-02-22 | Encodia, Inc. | METHODS OF PREPARATION OF ANALYTES AND RELATED KITS |
| CN112941634B (zh) * | 2019-12-10 | 2023-09-26 | 成都先导药物开发股份有限公司 | 通过dna编码化合物库筛选同时结合多个生物靶标的化合物的方法 |
| US20240209350A1 (en) * | 2021-04-26 | 2024-06-27 | European Molecular Biology Laboratory | High complexity microcompartment-based interaction screening |
| GB202317973D0 (en) | 2023-11-24 | 2024-01-10 | Nuclera Ltd | Use of DNA encoded libraries |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| EP1123305A1 (en) | 1998-10-19 | 2001-08-16 | The Board Of Trustees Of The Leland Stanford Junior University | Dna-templated combinatorial library chemistry |
| EP1423400B2 (en) | 2001-03-19 | 2013-05-22 | President and Fellows of Harvard College | Evolving new molecular function |
| ATE371026T1 (de) | 2001-06-20 | 2007-09-15 | Nuevolution As | Eine methode zur synthese von matrizenabhängigen molekülen |
| EP1670939B1 (en) * | 2003-09-18 | 2009-11-04 | Nuevolution A/S | A method for obtaining structural information concerning an encoded molecule and method for selecting compounds |
| CN1898257B (zh) * | 2003-12-17 | 2010-06-23 | 普雷西斯药品公司 | 合成编码文库的方法 |
| US7968287B2 (en) * | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| WO2006047791A2 (en) * | 2004-10-27 | 2006-05-04 | The Board Of Trustees Of The Leland Stanford Junior University | Dna-templated combinatorial library device and method for use |
| DK1809743T3 (da) * | 2004-11-08 | 2009-05-04 | Vipergen Aps | Strukturel nukleinsyre-styret kemisk syntese |
| EP1828381B1 (en) | 2004-11-22 | 2009-01-07 | Peter Birk Rasmussen | Template directed split and mix systhesis of small molecule libraries |
| WO2008103900A2 (en) | 2007-02-23 | 2008-08-28 | New England Biolabs, Inc. | Selection and enrichment of proteins using in vitro compartmentalization |
| CA2704226A1 (en) * | 2007-11-01 | 2009-05-07 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Cell-free methods for detecting protein-ligand interctions |
| US8153446B2 (en) | 2008-05-23 | 2012-04-10 | Kent State University | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems |
| EP2452195A4 (en) * | 2009-07-07 | 2012-12-05 | Agency Science Tech & Res | METHODS OF IDENTIFYING A PAIR OF LIAISON PARTNERS |
| WO2012041633A1 (en) * | 2010-09-27 | 2012-04-05 | Vipergen | A method for making an enriched library |
-
2011
- 2011-09-01 WO PCT/EP2011/065117 patent/WO2012041633A1/en not_active Ceased
- 2011-09-01 CN CN201180046388.3A patent/CN103119165B/zh active Active
- 2011-09-01 DK DK18161280.5T patent/DK3399035T3/da active
- 2011-09-01 DK DK11749853.5T patent/DK2622073T5/en active
- 2011-09-01 CA CA2808656A patent/CA2808656C/en active Active
- 2011-09-01 US US13/636,668 patent/US20130288929A1/en not_active Abandoned
- 2011-09-01 EP EP18161280.5A patent/EP3399035B1/en active Active
- 2011-09-01 EP EP11749853.5A patent/EP2622073B1/en not_active Not-in-force
- 2011-09-01 JP JP2013530661A patent/JP6193761B2/ja active Active
-
2013
- 2013-02-13 IL IL224694A patent/IL224694B/en active IP Right Grant
-
2016
- 2016-11-28 JP JP2016229846A patent/JP2017060513A/ja active Pending
- 2016-11-30 US US15/364,337 patent/US10513700B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2622073B1 (en) | 2018-04-18 |
| JP2013540440A (ja) | 2013-11-07 |
| JP6193761B2 (ja) | 2017-09-06 |
| WO2012041633A1 (en) | 2012-04-05 |
| CA2808656A1 (en) | 2012-04-05 |
| DK3399035T3 (da) | 2021-05-17 |
| JP2017060513A (ja) | 2017-03-30 |
| IL224694B (en) | 2018-08-30 |
| US20130288929A1 (en) | 2013-10-31 |
| EP3399035A1 (en) | 2018-11-07 |
| IL224694A0 (en) | 2013-07-31 |
| CN103119165A (zh) | 2013-05-22 |
| CN103119165B (zh) | 2017-04-12 |
| US20170233726A1 (en) | 2017-08-17 |
| EP3399035B1 (en) | 2021-02-17 |
| DK2622073T3 (da) | 2018-07-30 |
| US10513700B2 (en) | 2019-12-24 |
| DK2622073T5 (en) | 2019-02-25 |
| EP2622073A1 (en) | 2013-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20160831 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 13TH ANNIV.) - STANDARD Year of fee payment: 13 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20240823 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20240823 |
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| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 14TH ANNIV.) - STANDARD Year of fee payment: 14 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250822 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250822 |