IL222796A0 - Micropellet compositions comprising pancreatin containing digestive enzyme mixtures - Google Patents

Micropellet compositions comprising pancreatin containing digestive enzyme mixtures

Info

Publication number
IL222796A0
IL222796A0 IL222796A IL22279612A IL222796A0 IL 222796 A0 IL222796 A0 IL 222796A0 IL 222796 A IL222796 A IL 222796A IL 22279612 A IL22279612 A IL 22279612A IL 222796 A0 IL222796 A0 IL 222796A0
Authority
IL
Israel
Prior art keywords
micropellet
compositions
digestive enzyme
enzyme mixtures
containing digestive
Prior art date
Application number
IL222796A
Original Assignee
Aptalis Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aptalis Pharma Ltd filed Critical Aptalis Pharma Ltd
Publication of IL222796A0 publication Critical patent/IL222796A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
IL222796A 2010-05-03 2012-11-01 Micropellet compositions comprising pancreatin containing digestive enzyme mixtures IL222796A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33076810P 2010-05-03 2010-05-03
PCT/US2011/035023 WO2011140106A1 (en) 2010-05-03 2011-05-03 Micropellet compositions comprising pancreatin containing digestive enzyme mixtures

Publications (1)

Publication Number Publication Date
IL222796A0 true IL222796A0 (en) 2012-12-31

Family

ID=44904036

Family Applications (1)

Application Number Title Priority Date Filing Date
IL222796A IL222796A0 (en) 2010-05-03 2012-11-01 Micropellet compositions comprising pancreatin containing digestive enzyme mixtures

Country Status (10)

Country Link
EP (1) EP2566466A1 (en)
JP (1) JP2013525488A (en)
CN (1) CN102946872A (en)
AU (1) AU2011248293A1 (en)
CA (1) CA2798280A1 (en)
CO (1) CO6640298A2 (en)
IL (1) IL222796A0 (en)
MX (1) MX2012012794A (en)
RU (1) RU2012148776A (en)
WO (1) WO2011140106A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014346930A1 (en) * 2013-11-05 2016-01-07 Aptalis Pharma Ltd. High potency pancreatin pharmaceutical compositions
MX2017004473A (en) * 2014-10-08 2017-10-12 Synthetic Biologics Inc Beta-lactamase formulations and uses thereof.
CN104906565B (en) * 2015-05-13 2018-06-19 西南大学 A kind of pancreatic enzymes enteric coated pellets and preparation method thereof
CN106237315A (en) * 2016-08-02 2016-12-21 马南行 A kind of compositions of external curing diabetes and preparation method thereof
IT201700021852A1 (en) * 2017-02-27 2018-08-27 Bioscreen Tech S R L RELEASED COMPOSITION OF PHYSIOLOGICALLY ACTIVE SUBSTANCES AND PROCESS FOR ITS PREPARATION
IT201700021879A1 (en) 2017-02-27 2018-08-27 Bioscreen Tech S R L RELEASED COMPOSITION OF PHYSIOLOGICALLY ACTIVE SUBSTANCES AND PROCESS FOR ITS PREPARATION
DE102017104501A1 (en) 2017-03-03 2018-09-06 Nordmark Arzneimittel Gmbh & Co. Kg A pharmaceutical composition comprising a carrier and a coating containing at least one lipase
DE102017104482A1 (en) 2017-03-03 2018-09-06 Nordmark Arzneimittel Gmbh & Co. Kg A pharmaceutical composition comprising pancreatin and a lipase-containing coating
SG11202007976WA (en) * 2018-02-23 2020-09-29 MUCPharm Pty Ltd Formulations containing mucin-affecting proteases
CN108531538A (en) * 2018-04-08 2018-09-14 武汉藤欣生物工程有限公司 A kind of method that enzyme process prepares phytosterin ester
NL2021893B1 (en) 2018-10-26 2020-05-13 Citeq B V Biological pest control agent
CN110075279A (en) * 2019-04-25 2019-08-02 淮安麦德森制药有限公司 Pancreatin microballoon and its production method
CN110331138A (en) * 2019-06-29 2019-10-15 南京永正生物科技有限公司 A kind of production technology of biological complex enzyme microcapsules
RU2706003C1 (en) * 2019-09-09 2019-11-13 Акционерное общество "АВВА РУС" Microgranules containing pancreatin
CN112220916A (en) * 2020-10-26 2021-01-15 西南药业股份有限公司 Preparation process of biological enzyme tablet and product thereof
CN114767639A (en) * 2022-05-13 2022-07-22 天津博菲德科技有限公司 Acid-resistant enzyme preparation granule and preparation method thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4227385A1 (en) * 1992-08-19 1994-02-24 Kali Chemie Pharma Gmbh Pancreatin micropellets
DK1162995T3 (en) * 1999-03-17 2003-06-23 Solvay Pharm Gmbh Enzymes for the treatment of type I diabetes mellitus
IT1319655B1 (en) * 2000-11-15 2003-10-23 Eurand Int PANCREATIC ENZYME MICROSPHERES WITH HIGH STABILITY AND RELATIVE PREPARATION METHOD.
US7578951B2 (en) * 2004-01-27 2009-08-25 Hewlett-Packard Development Company, L.P. Method of making microcapsules utilizing a fluid ejector
US20050214371A1 (en) * 2004-03-03 2005-09-29 Simona Di Capua Stable pharmaceutical composition comprising an acid labile drug
UA89102C2 (en) * 2005-08-15 2009-12-25 Солвей Фармасьютикалс Гмбх pancreatin micropellet cores SUITABLE FOR application of enterosoluble coating
US11266607B2 (en) * 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
WO2007020259A2 (en) * 2005-08-15 2007-02-22 Solvay Pharmaceuticals Gmbh Controlled release pharmaceutical compositions for acid labile drugs
MY163469A (en) * 2007-02-20 2017-09-15 Allergan Therapeutics LLC Stable digestive enzyme compositions
CN101279091A (en) * 2007-04-04 2008-10-08 常州市第四制药厂有限公司 Pancreatic enzymes enteric coated pellets and preparation

Also Published As

Publication number Publication date
CN102946872A (en) 2013-02-27
WO2011140106A1 (en) 2011-11-10
RU2012148776A (en) 2014-06-10
JP2013525488A (en) 2013-06-20
AU2011248293A1 (en) 2012-11-15
CO6640298A2 (en) 2013-03-22
EP2566466A1 (en) 2013-03-13
CA2798280A1 (en) 2011-11-10
MX2012012794A (en) 2013-03-12

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