CN106237315A - A kind of compositions of external curing diabetes and preparation method thereof - Google Patents
A kind of compositions of external curing diabetes and preparation method thereof Download PDFInfo
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- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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Abstract
The invention discloses compositions of a kind of external curing diabetes and preparation method thereof.The composition of described compositions includes: papain, amylolytic enzyme, lipolytic enzyme, saccharifying enzyme, Sargassum extract, Ba Naba extract, Citrus polyphenol, tetrahydrochysene piperine, Herb Gynostemmae Pentaphylli, leaf of Cyclocarya paliurus Iljinskaja, Radix Trichosanthis, bee pollen, Rhizoma Coptidis, Semen Litchi, screw oil expeller axle herb, Herba Agrimoniae, Herba Portulacae, herb Radix Ophiopogonis, Fructus Momordicae charantiae, anion powder, infrared ceramic powder, heat sensitizer.The Chinese medicine composition of the present invention can be used for outward treating diabetes, has heat-clearing and toxic substances removing, regulating qi-flowing for strengthening spleen, hypoglycemic effect, treats diabetes instant effect, short treating period, does not recurs.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine, be specifically related to compositions and the system thereof of a kind of external curing diabetes
Preparation Method.
Background technology
Diabetes are one group of metabolic diseases being characterized with hyperglycemia.Hyperglycemia be then due to defect of insulin secretion or
Its biological agent is impaired, or both have concurrently and cause.Long-standing hyperglycemia during diabetes, causes various tissue, particularly eye,
Kidney, heart, blood vessel, neural chronic lesion, dysfunction.The common condition of diabetes has polydipsia, polyuria, polyphagia and becomes thin
Deng.
The most common Chinese medicine for treating diabetes goods are how main to be adjusted to, and have that effect is slow, the length course for the treatment of, effect are paid no attention to
The defect thought.And existing Chinese medicine product is for oral administration more, Chinese medicine for oral administration, for the patient of weakness of the spleen and stomach, is not only inhaled
Receive slow, and easily cause spleen injury, even increase the weight of the state of an illness.
Summary of the invention
It is an object of the invention to provide compositions of a kind of external curing diabetes and preparation method thereof.
The technical solution used in the present invention is:
The compositions of a kind of external curing diabetes, its composition includes: papain, amylolytic enzyme, lipolytic enzyme, sugar
Change enzyme, Sargassum extract, Ba Naba extract, Citrus polyphenol, tetrahydrochysene piperine, Herb Gynostemmae Pentaphylli, leaf of Cyclocarya paliurus Iljinskaja, Radix Trichosanthis, Herba leucadis ciliatae
Powder, Rhizoma Coptidis, Semen Litchi, screw oil expeller axle herb, Herba Agrimoniae, Herba Portulacae, herb Radix Ophiopogonis, Fructus Momordicae charantiae, anion powder, infrared ceramic powder,
Heat sensitizer.
As preferably, the composition of the compositions of described external curing diabetes includes: papain 0.1-1.0
Part, amylolytic enzyme 0.1-5 part, lipolytic enzyme 0.01-0.50 part, saccharifying enzyme 0.01-0.50 part, Sargassum extract 1-2 part,
Ba Naba extract 1-2 part, Citrus polyphenol 0.1-1.0 part, tetrahydrochysene piperine 0.5-1.0 part, Herb Gynostemmae Pentaphylli 5-10 part, leaf of Cyclocarya paliurus Iljinskaja
15-20 part, Radix Trichosanthis 2-4 part, bee pollen 1-2 part, Rhizoma Coptidis 2-4 part, Semen Litchi 6-12 part, screw oil expeller axle herb 8-12 part, red crowned crane
Grass 4-8 part, Herba Portulacae 10-20 part, herb 5-10 part Radix Ophiopogonis, Fructus Momordicae charantiae 5-10 part, anion powder 5-10 part, infrared ceramic powder 5-
10 parts, heat sensitizer 5-10 part.
It is further preferred that the composition of the compositions of described external curing diabetes includes: papain 0.1-0.5
Part, amylolytic enzyme 1.0-2.0 part, lipolytic enzyme 0.10-0.50 part, saccharifying enzyme 0.10-0.50 part, Sargassum extract 2 parts,
Ba Naba extract 2 parts, Citrus polyphenol 0.5 part, tetrahydrochysene piperine 1.0 parts, Herb Gynostemmae Pentaphylli 5-10 part, leaf of Cyclocarya paliurus Iljinskaja 15-20 part, sky
Pollen 2-4 part, bee pollen 1-2 part, Rhizoma Coptidis 2-4 part, Semen Litchi 6-12 part, screw oil expeller axle herb 8-12 part, Herba Agrimoniae 4-8 part, horse
Bitterroot 10-20 part, herb 5-10 part Radix Ophiopogonis, Fructus Momordicae charantiae 5-10 part, anion powder 10 parts, 5 parts of infrared ceramic powder, heat sensitizer 10
Part.
The preparation method of the compositions of above-described external curing diabetes is as follows:
(1) by Herb Gynostemmae Pentaphylli, leaf of Cyclocarya paliurus Iljinskaja, Radix Trichosanthis, bee pollen, Rhizoma Coptidis, Semen Litchi, screw oil expeller axle herb, Herba Agrimoniae, Herba Portulacae,
Radix Ophiopogonis herb, after the material disintegrating such as Fructus Momordicae charantiae, be sequentially added into papain, amylolytic enzyme, lipolytic enzyme, saccharifying enzyme are carried out
Enzymolysis pre-treatment, hot dipping 6-12 hour at 45-85 DEG C of the product ethanol water after each enzymolysis, reclaim ethanol, concentration,
It is dried, then carries out enzymolysis next time with water dissolution;
(2) the sufficient mixture of enzymolysis obtains mixture A after drying, continuously adds Sargassum extract, Ba Naba extract, Citrus
Polyphenol, tetrahydrochysene piperine, anion powder, infrared ceramic powder and heat sensitizer, be uniformly mixed, and obtains mixture B;
(3) toward mixture B adds cream substrate, be further prepared into cream, emulsion, essence, washing liquid, spraying, patch or
Gel.
Described ethanol water refers to the ethanol water that volumetric concentration is 45-75%.
The invention has the beneficial effects as follows: the Chinese medicine composition of the present invention can be used for outward treating diabetes, have heat-clearing and toxic substances removing,
Regulating qi-flowing for strengthening spleen, hypoglycemic effect, treat diabetes instant effect, short treating period, do not recur.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail, but do not constitute and appoint the present invention
What limits, the change of anyone limited number of time made within the scope of the invention as claimed, and still the claim in the present invention is protected
In the range of protecting.
Embodiment 1
The compositions of a kind of external curing diabetes, its composition includes: papain 0.1 part, amylolytic enzyme 1.5 parts, fat
Fat catabolic enzyme 0.50 part, saccharifying enzyme 0.10 part, Sargassum extract 2 parts, Ba Naba extract 2 parts, Citrus polyphenol 0.5 part, tetrahydrochysene
Piperine 1.0 parts, Herb Gynostemmae Pentaphylli 5 parts, leaf of Cyclocarya paliurus Iljinskaja 15 parts, Radix Trichosanthis 2 parts, bee pollen 1 part, Rhizoma Coptidis 2 parts, Semen Litchi 6 parts, screw oil expeller
Axle herb 12 parts, Herba Agrimoniae 8 parts, Herba Portulacae 10 parts, herb Radix Ophiopogonis 5 parts, 5 parts of Fructus Momordicae charantiae, anion powder 10 parts, infrared ceramic powder
5 parts, heat sensitizer 10 parts.
Embodiment 2
The compositions of a kind of external curing diabetes, its composition includes: papain 0.5 part, amylolytic enzyme 2.0 parts, fat
Fat catabolic enzyme 0.25 part, saccharifying enzyme 0.25 part, Sargassum extract 2 parts, Ba Naba extract 2 parts, Citrus polyphenol 0.5 part, tetrahydrochysene
Piperine 1.0 parts, Herb Gynostemmae Pentaphylli 10 parts, leaf of Cyclocarya paliurus Iljinskaja 20 parts, Radix Trichosanthis 3 parts, bee pollen 1.5 parts, Rhizoma Coptidis 4 parts, Semen Litchi 10 parts,
Screw oil expeller axle herb 8 parts, Herba Agrimoniae 6 parts, Herba Portulacae 15 parts, herb Radix Ophiopogonis 8 parts, 10 parts of Fructus Momordicae charantiae, anion powder 10 parts, infrared ceramic
5 parts of porcelain powder, heat sensitizer 10 parts.
Embodiment 3
The compositions of a kind of external curing diabetes, its composition includes: papain 0.5 part, amylolytic enzyme 2.0 parts, fat
Fat catabolic enzyme 0.50 part, saccharifying enzyme 0.50 part, Sargassum extract 2 parts, Ba Naba extract 2 parts, Citrus polyphenol 0.5 part, tetrahydrochysene
Piperine 1.0 parts, Herb Gynostemmae Pentaphylli 8 parts, leaf of Cyclocarya paliurus Iljinskaja 15 parts, Radix Trichosanthis 4 parts, bee pollen 1 part, Rhizoma Coptidis 3 parts, Semen Litchi 12 parts, red
Axletree herb 10 parts, Herba Agrimoniae 4 parts, Herba Portulacae 20 parts, herb Radix Ophiopogonis 10 parts, 8 parts of Fructus Momordicae charantiae, anion powder 10 parts, infrared ceramic
5 parts of porcelain powder, heat sensitizer 10 parts.
Embodiment 4
The compositions of the external curing diabetes described in claim 1-3 is prepared as external preparation:
(1) by Herb Gynostemmae Pentaphylli, leaf of Cyclocarya paliurus Iljinskaja, Radix Trichosanthis, bee pollen, Rhizoma Coptidis, Semen Litchi, screw oil expeller axle herb, Herba Agrimoniae, Herba Portulacae,
Radix Ophiopogonis herb, after the material disintegrating such as Fructus Momordicae charantiae, be sequentially added into papain, amylolytic enzyme, lipolytic enzyme, saccharifying enzyme are carried out
Enzymolysis pre-treatment, hot dipping 6-12 hour at 45-85 DEG C of the product ethanol water after each enzymolysis, reclaim ethanol, concentration,
It is dried, then carries out enzymolysis next time with water dissolution;
(2) the sufficient mixture of enzymolysis obtains mixture A after drying, continuously adds Sargassum extract, Ba Naba extract, Citrus
Polyphenol, tetrahydrochysene piperine, anion powder, infrared ceramic powder and heat sensitizer, be uniformly mixed, and obtains mixture B;
(3) toward mixture B adds cream substrate, be further prepared into cream, emulsion, essence, washing liquid, spraying, patch or
Gel.
Embodiment 5 clinical practice (as a example by the compositions of the external curing diabetes of embodiment 2)
Zhang, female, 62 years old, clinical diagnosis was diabetes: bulimia, body weight alleviate to 45.5 kilograms from 55 kilograms of exceptions.
It is appropriate that every morning takes this product, is applied on front side of arm, is massaged into absorption.After 3 months on probation, appetite recovers normal.After 6 months
Weight recovery to 50 kilograms, life, diet normal.Adhere to using 2 years, without recurrence.
Lin, man, 57 years old, clinical diagnosis was diabetes: abnormal food appetite is hyperfunction, eats five or six meals every day and is not met by
Appetite, body weight alleviates to 68 kilograms from 76 kilograms of exceptions.It is appropriate that every morning takes this product, is applied on front side of arm, is massaged into suction
Receive.After 2 months on probation, appetite recovers normal.After 6 months, weight recovery is to 72 kilograms, life, diet normal.Adhere to using 2 years,
Without recurrence.
Chen, man, 57 years old, clinical diagnosis was diabetes: abnormal food appetite is hyperfunction, thirsty frequent micturition, and body weight is different from 72 kilograms
Often alleviate to 65 kilograms.It is appropriate that every morning takes this product, is applied on front side of arm, is massaged into absorption.After 2 months on probation, appetite is extensive
Multiple normal.After 6 months, weight recovery is to 70 kilograms, life, diet normal.Adhere to using 2 years, without recurrence.
Claims (5)
1. a compositions for external curing diabetes, its composition includes: papain, amylolytic enzyme, lipolytic enzyme,
Saccharifying enzyme, Sargassum extract, Ba Naba extract, Citrus polyphenol, tetrahydrochysene piperine, Herb Gynostemmae Pentaphylli, leaf of Cyclocarya paliurus Iljinskaja, Radix Trichosanthis, honeybee
Pollen, Rhizoma Coptidis, Semen Litchi, screw oil expeller axle herb, Herba Agrimoniae, Herba Portulacae, herb Radix Ophiopogonis, Fructus Momordicae charantiae, anion powder, infrared ceramic
Powder, heat sensitizer.
The compositions of external curing diabetes the most according to claim 1, it is characterised in that its composition includes: Fructus Chaenomelis egg
White enzyme 0.1-1.0 part, amylolytic enzyme 0.1-5 part, lipolytic enzyme 0.01-0.50 part, saccharifying enzyme 0.01-0.50 part, Sargassum
Extract 1-2 part, Ba Naba extract 1-2 part, Citrus polyphenol 0.1-1.0 part, tetrahydrochysene piperine 0.5-1.0 part, Herb Gynostemmae Pentaphylli 5-
10 parts, leaf of Cyclocarya paliurus Iljinskaja 15-20 part, Radix Trichosanthis 2-4 part, bee pollen 1-2 part, Rhizoma Coptidis 2-4 part, Semen Litchi 6-12 part, screw oil expeller axle complete
Grass 8-12 part, Herba Agrimoniae 4-8 part, Herba Portulacae 10-20 part, herb 5-10 part Radix Ophiopogonis, Fructus Momordicae charantiae 5-10 part, anion powder 5-10 part,
Infrared ceramic powder 5-10 part, heat sensitizer 5-10 part.
The compositions of external curing diabetes the most according to claim 2, it is characterised in that its composition includes: Fructus Chaenomelis egg
White enzyme 0.1-0.5 part, amylolytic enzyme 1.0-2.0 part, lipolytic enzyme 0.10-0.50 part, saccharifying enzyme 0.10-0.50 part, sea
Algae extract 2 parts, Ba Naba extract 2 parts, Citrus polyphenol 0.5 part, tetrahydrochysene piperine 1.0 parts, Herb Gynostemmae Pentaphylli 5-10 part, Cyclocarya paliurus Iljinskaja
Leaf 15-20 part, Radix Trichosanthis 2-4 part, bee pollen 1-2 part, Rhizoma Coptidis 2-4 part, Semen Litchi 6-12 part, screw oil expeller axle herb 8-12 part, celestial being
Crane grass 4-8 part, Herba Portulacae 10-20 part, herb 5-10 part Radix Ophiopogonis, Fructus Momordicae charantiae 5-10 part, anion powder 10 parts, infrared ceramic powder 5
Part, heat sensitizer 10 parts.
4. according to the compositions of the external curing diabetes described in any one of claim 1-3, it is characterised in that described compositions
Preparation method as follows:
(1) by Herb Gynostemmae Pentaphylli, leaf of Cyclocarya paliurus Iljinskaja, Radix Trichosanthis, bee pollen, Rhizoma Coptidis, Semen Litchi, screw oil expeller axle herb, Herba Agrimoniae, Herba Portulacae,
Radix Ophiopogonis herb, after the material disintegrating such as Fructus Momordicae charantiae, be sequentially added into papain, amylolytic enzyme, lipolytic enzyme, saccharifying enzyme are carried out
Enzymolysis pre-treatment, hot dipping 6-12 hour at 45-85 DEG C of the product ethanol water after each enzymolysis, reclaim ethanol, concentration,
It is dried, then carries out enzymolysis next time with water dissolution;
(2) the sufficient mixture of enzymolysis obtains mixture A after drying, continuously adds Sargassum extract, Ba Naba extract, Citrus
Polyphenol, tetrahydrochysene piperine, anion powder, infrared ceramic powder and heat sensitizer, be uniformly mixed, and obtains mixture B;
(3) toward mixture B adds cream substrate, be further prepared into cream, emulsion, essence, washing liquid, spraying, patch or
Gel.
The compositions of external curing diabetes the most according to claim 4, it is characterised in that described ethanol water refers to
Volumetric concentration is the ethanol water of 45-75%.
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1403146A (en) * | 2002-10-24 | 2003-03-19 | 河北以岭医药研究院有限公司 | Medicines composition for treating diabetes and its prepn |
CN102946872A (en) * | 2010-05-03 | 2013-02-27 | 阿普塔利斯制药有限公司 | Micropellet compositions comprising pancreatin containing digestive enzyme mixtures |
CN103446503A (en) * | 2013-07-26 | 2013-12-18 | 杨德俊 | Traditional Chinese medicine composition for treating type II diabetes mellitus |
CN103750102A (en) * | 2013-12-31 | 2014-04-30 | 南京润寿缘生物科技有限公司 | Composition with sugar-reducing effect and containing blackberries and preparation method for composition |
CN105434509A (en) * | 2015-12-25 | 2016-03-30 | 兰州大学 | Preparation method of trifolium pratense linn extract and application thereof in reduction of blood glucose |
-
2016
- 2016-08-02 CN CN201610623058.0A patent/CN106237315A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1403146A (en) * | 2002-10-24 | 2003-03-19 | 河北以岭医药研究院有限公司 | Medicines composition for treating diabetes and its prepn |
CN102946872A (en) * | 2010-05-03 | 2013-02-27 | 阿普塔利斯制药有限公司 | Micropellet compositions comprising pancreatin containing digestive enzyme mixtures |
CN103446503A (en) * | 2013-07-26 | 2013-12-18 | 杨德俊 | Traditional Chinese medicine composition for treating type II diabetes mellitus |
CN103750102A (en) * | 2013-12-31 | 2014-04-30 | 南京润寿缘生物科技有限公司 | Composition with sugar-reducing effect and containing blackberries and preparation method for composition |
CN105434509A (en) * | 2015-12-25 | 2016-03-30 | 兰州大学 | Preparation method of trifolium pratense linn extract and application thereof in reduction of blood glucose |
Non-Patent Citations (1)
Title |
---|
蔡仲德,等: "中医药治疗糖尿病研究概况", 《中国实验方剂学杂志》 * |
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