IL217531A0 - Compounds as hypoxia mimetics, and compositions, and uses thereof - Google Patents
Compounds as hypoxia mimetics, and compositions, and uses thereofInfo
- Publication number
- IL217531A0 IL217531A0 IL217531A IL21753112A IL217531A0 IL 217531 A0 IL217531 A0 IL 217531A0 IL 217531 A IL217531 A IL 217531A IL 21753112 A IL21753112 A IL 21753112A IL 217531 A0 IL217531 A0 IL 217531A0
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- compounds
- hypoxia mimetics
- mimetics
- hypoxia
- Prior art date
Links
- 206010021143 Hypoxia Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000007954 hypoxia Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910089274 | 2009-07-15 | ||
| PCT/CN2010/001057 WO2011006355A1 (en) | 2009-07-15 | 2010-07-14 | Compounds as hypoxia mimetics, and compositions, and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL217531A0 true IL217531A0 (en) | 2012-02-29 |
Family
ID=43448908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL217531A IL217531A0 (en) | 2009-07-15 | 2012-01-12 | Compounds as hypoxia mimetics, and compositions, and uses thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8742138B2 (enExample) |
| EP (1) | EP2454249B1 (enExample) |
| JP (1) | JP5847710B2 (enExample) |
| KR (1) | KR20120065311A (enExample) |
| CN (1) | CN102164905B (enExample) |
| AU (1) | AU2010273101B2 (enExample) |
| CA (1) | CA2767911C (enExample) |
| ES (1) | ES2702524T3 (enExample) |
| IL (1) | IL217531A0 (enExample) |
| IN (1) | IN2012DN00549A (enExample) |
| SG (1) | SG177598A1 (enExample) |
| WO (1) | WO2011006355A1 (enExample) |
| ZA (1) | ZA201200293B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2606631T3 (es) | 2011-07-22 | 2017-03-24 | Beijing Betta Pharmaceuticals Co., Ltd | Formas polimeróficas de compuestos como inhibidor de la prolila hidroxilasa, y usos de los mismos |
| JP2014523917A (ja) * | 2011-07-29 | 2014-09-18 | ベイジン ベータ ファーマシューティカルズ カンパニー， リミテッド | 低酸素模倣剤としての化合物の安定な多形体、およびその使用 |
| CN105384687B (zh) | 2014-09-02 | 2018-05-01 | 广东东阳光药业有限公司 | 喹啉酮类化合物及其在药物中应用 |
| US20160193238A1 (en) * | 2015-01-05 | 2016-07-07 | National Cancer Center | HNF4-alpha ANTAGONIST AND USE THEREOF |
| CN113694077A (zh) * | 2015-08-13 | 2021-11-26 | 索马根尼科斯公司 | 用于伤口愈合的短小发夹rna与微rna的组合物以及方法 |
| AU2018264313B2 (en) | 2017-05-09 | 2020-06-04 | Kind Pharmaceutical | Indolizine derivatives and application thereof in medicine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003228348A1 (en) * | 2002-03-20 | 2003-10-08 | John T. Fassett | Induction of hepatocyte proliferation in vitro by inhibition of cell cycle inhibitors |
| CA2618770A1 (en) * | 2005-08-25 | 2007-03-01 | Emory University | Hif inhibitors |
| WO2007038571A2 (en) * | 2005-09-26 | 2007-04-05 | Smithkline Beecham Corporation | Prolyl hydroxylase antagonists |
| CA2634168C (en) | 2005-12-09 | 2013-04-23 | Amgen Inc. | Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof |
| TW200808793A (en) * | 2006-03-07 | 2008-02-16 | Smithkline Beecham Corp | Prolyl hydroxylase inhibitors |
| PL2134720T3 (pl) * | 2007-03-29 | 2011-04-29 | Novartis Ag | Heterocykliczne spiro-związki |
| US8324405B2 (en) * | 2008-02-05 | 2012-12-04 | Fibrogen, Inc. | Chromene derivatives and use thereof as HIF hydroxylase activity inhibitors |
| EP2341904A1 (en) * | 2008-08-26 | 2011-07-13 | Fibrogen, Inc. | Methods for treatment of multiple sclerosis |
-
2010
- 2010-07-14 IN IN549DEN2012 patent/IN2012DN00549A/en unknown
- 2010-07-14 AU AU2010273101A patent/AU2010273101B2/en not_active Ceased
- 2010-07-14 ES ES10799353T patent/ES2702524T3/es active Active
- 2010-07-14 KR KR1020127001420A patent/KR20120065311A/ko not_active Ceased
- 2010-07-14 CN CN201080002367.7A patent/CN102164905B/zh not_active Expired - Fee Related
- 2010-07-14 WO PCT/CN2010/001057 patent/WO2011006355A1/en not_active Ceased
- 2010-07-14 JP JP2012519871A patent/JP5847710B2/ja not_active Expired - Fee Related
- 2010-07-14 US US13/384,097 patent/US8742138B2/en active Active
- 2010-07-14 CA CA2767911A patent/CA2767911C/en not_active Expired - Fee Related
- 2010-07-14 EP EP10799353.7A patent/EP2454249B1/en not_active Not-in-force
- 2010-07-14 SG SG2012001806A patent/SG177598A1/en unknown
-
2012
- 2012-01-12 IL IL217531A patent/IL217531A0/en unknown
- 2012-01-13 ZA ZA2012/00293A patent/ZA201200293B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2767911A1 (en) | 2011-01-20 |
| CA2767911C (en) | 2016-03-29 |
| HK1161234A1 (en) | 2012-08-24 |
| EP2454249A1 (en) | 2012-05-23 |
| JP5847710B2 (ja) | 2016-01-27 |
| CN102164905B (zh) | 2014-04-30 |
| EP2454249A4 (en) | 2012-12-12 |
| CN102164905A (zh) | 2011-08-24 |
| ZA201200293B (en) | 2012-09-26 |
| US8742138B2 (en) | 2014-06-03 |
| IN2012DN00549A (enExample) | 2015-06-12 |
| AU2010273101B2 (en) | 2016-02-25 |
| WO2011006355A1 (en) | 2011-01-20 |
| KR20120065311A (ko) | 2012-06-20 |
| AU2010273101A2 (en) | 2012-03-15 |
| EP2454249B1 (en) | 2018-09-19 |
| AU2010273101A1 (en) | 2012-02-02 |
| JP2012532897A (ja) | 2012-12-20 |
| SG177598A1 (en) | 2012-02-28 |
| US20120172399A1 (en) | 2012-07-05 |
| ES2702524T3 (es) | 2019-03-01 |
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