IL216649A0 - Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide - Google Patents

Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide

Info

Publication number
IL216649A0
IL216649A0 IL216649A IL21664911A IL216649A0 IL 216649 A0 IL216649 A0 IL 216649A0 IL 216649 A IL216649 A IL 216649A IL 21664911 A IL21664911 A IL 21664911A IL 216649 A0 IL216649 A0 IL 216649A0
Authority
IL
Israel
Prior art keywords
carbamoylamino
polymorphs
carboxamide
phenoxy
trifluoromethyl
Prior art date
Application number
IL216649A
Other languages
English (en)
Original Assignee
Ratiopharm Gmbh
Gidwani Ramesh Matioram
Wakchaure Vikas S
Stiegel Hans Gunter
Albrecht Wolfgang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh, Gidwani Ramesh Matioram, Wakchaure Vikas S, Stiegel Hans Gunter, Albrecht Wolfgang filed Critical Ratiopharm Gmbh
Publication of IL216649A0 publication Critical patent/IL216649A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
IL216649A 2009-06-12 2011-11-28 Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide IL216649A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1395CH2009 2009-06-12
PCT/EP2010/058006 WO2010142678A2 (en) 2009-06-12 2010-06-08 Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide

Publications (1)

Publication Number Publication Date
IL216649A0 true IL216649A0 (en) 2012-02-29

Family

ID=42931997

Family Applications (1)

Application Number Title Priority Date Filing Date
IL216649A IL216649A0 (en) 2009-06-12 2011-11-28 Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide

Country Status (3)

Country Link
EP (1) EP2440531A2 (en18)
IL (1) IL216649A0 (en18)
WO (1) WO2010142678A2 (en18)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010299484A1 (en) * 2009-09-24 2012-05-03 Ranbaxy Laboratories Limited Polymorphs of sorafenib acid addition salts
WO2012071425A1 (en) 2010-11-22 2012-05-31 Teva Pharmaceutical Industries Ltd. Solid state forms of sorafenib besylate, and processes for preparations thereof
US9156789B2 (en) 2012-05-21 2015-10-13 Hetero Research Foundation Process for sorafenib tosylate polymorph III
US20150111929A1 (en) * 2012-05-23 2015-04-23 Shilpa Medicare Limited Process for preparing crystalline sorafenib tosylate
CN103570613B (zh) * 2012-07-18 2016-06-15 苏州泽璟生物制药有限公司 氘代ω-二苯基脲或其盐的多晶型物
CN106336377A (zh) * 2015-07-17 2017-01-18 苏州亚宝药物研发有限公司 一种甲苯磺酸索拉非尼晶型ⅱ的制备方法
EP3390362A4 (en) * 2015-12-14 2019-06-26 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. SORAFENIB-HEMI-P-TOSYLATE MONOHYDRATE CRYSTAL AND METHOD OF MANUFACTURING THEREOF
CN107759517A (zh) * 2016-08-23 2018-03-06 广州白云山医药集团股份有限公司白云山制药总厂 一种甲苯磺酸索拉非尼晶型ⅰ的制备方法
RU2766288C2 (ru) * 2020-03-30 2022-03-11 Общество с ограниченной ответственностью "АКСЕЛЬФАРМ" Аморфная форма 4-{ 4-[({ [4-хлор-3-(трифторметил)фенил]амино} карбонил)-амино]фенокси} -n-метилпиридин-2-карбоксамида тозилата (варианты), способ её получения и применение для лечения онкологических заболеваний

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5128948B2 (ja) * 2004-08-27 2013-01-23 ニッポネックス インコーポレイテッド 癌の治療のための新規な薬剤組成物
NZ553804A (en) * 2004-09-29 2010-07-30 Bayer Schering Pharma Ag Thermodynamically stable form of bay 43-9006 tosylate
WO2006094626A1 (en) * 2005-03-07 2006-09-14 Bayer Healthcare Ag Pharmaceutical composition comprising an omega- carboxyaryl substituted diphenyl urea for the treatment of cancer
WO2007038524A2 (en) * 2005-09-28 2007-04-05 Ssci, Inc. Cocrystallization methods
CA2657379A1 (en) * 2006-07-10 2008-01-17 Elan Pharma International Ltd. Nanoparticulate sorafenib formulations
WO2009106825A1 (en) * 2008-02-27 2009-09-03 Cipla Limited Polymorphs of sorafenib and salts thereof
CN101584661B (zh) * 2009-06-10 2011-06-08 北京大学 一种供口服或静脉注射用索拉非尼自微乳化给药系统及其制备方法

Also Published As

Publication number Publication date
EP2440531A2 (en) 2012-04-18
WO2010142678A2 (en) 2010-12-16
WO2010142678A3 (en) 2011-03-24

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