IL216649A0 - Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide - Google Patents
Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamideInfo
- Publication number
- IL216649A0 IL216649A0 IL216649A IL21664911A IL216649A0 IL 216649 A0 IL216649 A0 IL 216649A0 IL 216649 A IL216649 A IL 216649A IL 21664911 A IL21664911 A IL 21664911A IL 216649 A0 IL216649 A0 IL 216649A0
- Authority
- IL
- Israel
- Prior art keywords
- carbamoylamino
- polymorphs
- carboxamide
- phenoxy
- trifluoromethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1395CH2009 | 2009-06-12 | ||
| PCT/EP2010/058006 WO2010142678A2 (en) | 2009-06-12 | 2010-06-08 | Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL216649A0 true IL216649A0 (en) | 2012-02-29 |
Family
ID=42931997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL216649A IL216649A0 (en) | 2009-06-12 | 2011-11-28 | Polymorphs of 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2440531A2 (en) |
| IL (1) | IL216649A0 (en) |
| WO (1) | WO2010142678A2 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011036648A1 (en) * | 2009-09-24 | 2011-03-31 | Ranbaxy Laboratories Limited | Polymorphs of sorafenib acid addition salts |
| WO2012071425A1 (en) | 2010-11-22 | 2012-05-31 | Teva Pharmaceutical Industries Ltd. | Solid state forms of sorafenib besylate, and processes for preparations thereof |
| WO2013175506A2 (en) * | 2012-05-21 | 2013-11-28 | Hetero Research Foundation | Process for sorafenib tosylate polymorph iii |
| EP2922820A4 (en) * | 2012-05-23 | 2016-06-01 | Shilpa Medicare Ltd | Process for preparing crystalline sorafenib tosylate |
| CN103570613B (en) * | 2012-07-18 | 2016-06-15 | 苏州泽璟生物制药有限公司 | The polymorphic form of deuterated ω-diphenyl urea or its salt |
| CN106336377A (en) * | 2015-07-17 | 2017-01-18 | 苏州亚宝药物研发有限公司 | Preparation method for crystal form II of sorafenib tosylate |
| CN108368052A (en) * | 2015-12-14 | 2018-08-03 | 正大天晴药业集团股份有限公司 | Half Sorafenib Tosylate hydrate crystallization and preparation method thereof |
| CN107759517A (en) * | 2016-08-23 | 2018-03-06 | 广州白云山医药集团股份有限公司白云山制药总厂 | A kind of preparation method of Sorafenib Tosylate crystal formation I |
| RU2766288C2 (en) * | 2020-03-30 | 2022-03-11 | Общество с ограниченной ответственностью "АКСЕЛЬФАРМ" | Amorphous form of 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)-amino]phenoxy}-n-methylpyridine-2-carboxamide tosylate (versions), method for production and use thereof for treatment of oncological diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005007048D1 (en) * | 2004-08-27 | 2008-07-03 | Bayer Pharmaceuticals Corp | PHARMACEUTICAL COMPOSITIONS IN THE FORM OF SOLID DISPERSIONS FOR THE TREATMENT OF CANCER |
| EP1797038B1 (en) * | 2004-09-29 | 2012-06-13 | Bayer Pharma Aktiengesellschaft | Thermodynamically stable form of bay 43-9006 tosylate |
| CA2601955C (en) * | 2005-03-07 | 2012-07-10 | Bayer Healthcare Ag | Pharmaceutical composition comprising an omega-carboxyaryl substituted diphenyl urea for the treatment of cancer |
| WO2007038524A2 (en) * | 2005-09-28 | 2007-04-05 | Ssci, Inc. | Cocrystallization methods |
| WO2008008733A2 (en) * | 2006-07-10 | 2008-01-17 | Elan Pharma International Ltd. | Nanoparticulate sorafenib formulations |
| WO2009106825A1 (en) * | 2008-02-27 | 2009-09-03 | Cipla Limited | Polymorphs of sorafenib and salts thereof |
| CN101584661B (en) * | 2009-06-10 | 2011-06-08 | 北京大学 | Preparation of sorafenib self-microemulsifying drug delivery system for oral administration or intravenous injection and use thereof |
-
2010
- 2010-06-08 EP EP10722711.8A patent/EP2440531A2/en not_active Withdrawn
- 2010-06-08 WO PCT/EP2010/058006 patent/WO2010142678A2/en active Application Filing
-
2011
- 2011-11-28 IL IL216649A patent/IL216649A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010142678A2 (en) | 2010-12-16 |
| EP2440531A2 (en) | 2012-04-18 |
| WO2010142678A3 (en) | 2011-03-24 |
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