IL213476A0 - Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles - Google Patents
Methods for treating multiple sclerosis using tetracyclic pyrazinoindolesInfo
- Publication number
- IL213476A0 IL213476A0 IL213476A IL21347611A IL213476A0 IL 213476 A0 IL213476 A0 IL 213476A0 IL 213476 A IL213476 A IL 213476A IL 21347611 A IL21347611 A IL 21347611A IL 213476 A0 IL213476 A0 IL 213476A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- multiple sclerosis
- treating multiple
- tetracyclic pyrazinoindoles
- pyrazinoindoles
- Prior art date
Links
- QKEBGAUJUHZNNU-UHFFFAOYSA-N 9h-pyrrolo[2,3-f]quinoxaline Chemical class N1=CC=NC2=C(NC=C3)C3=CC=C21 QKEBGAUJUHZNNU-UHFFFAOYSA-N 0.000 title 1
- 201000006417 multiple sclerosis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12157408P | 2008-12-11 | 2008-12-11 | |
| US23323509P | 2009-08-12 | 2009-08-12 | |
| PCT/US2009/067673 WO2010068867A1 (en) | 2008-12-11 | 2009-12-11 | Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL213476A0 true IL213476A0 (en) | 2011-07-31 |
Family
ID=42243090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL213476A IL213476A0 (en) | 2008-12-11 | 2011-06-12 | Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20110268699A1 (https=) |
| EP (1) | EP2375900B1 (https=) |
| JP (1) | JP2012512165A (https=) |
| CN (1) | CN102395275A (https=) |
| AU (1) | AU2009324495B2 (https=) |
| BR (1) | BRPI0922871A2 (https=) |
| CA (1) | CA2747235C (https=) |
| IL (1) | IL213476A0 (https=) |
| WO (1) | WO2010068867A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2340254B8 (en) | 2008-09-15 | 2014-05-21 | Biovista, Inc. | Compositions and methods for treating epilepsy |
| US10052299B2 (en) | 2009-10-30 | 2018-08-21 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| RU2436786C1 (ru) * | 2010-07-23 | 2011-12-20 | Александр Васильевич Иващенко | Замещенные индолы, противовирусный активный компонент, способ получения и применения |
| KR102112087B1 (ko) | 2011-04-26 | 2020-05-18 | 레트로토프 인코포레이티드 | 에너지 프로세싱 손상 장애 및 미토콘드리아 결함 |
| JP6145087B2 (ja) | 2011-04-26 | 2017-06-07 | レトロトップ、 インコーポレイテッドRetrotope, Inc. | Pufa酸化関与障害 |
| JP6106157B2 (ja) | 2011-04-26 | 2017-03-29 | レトロトップ、 インコーポレイテッドRetrotope, Inc. | 神経変性障害および筋疾患に関与するpufa |
| WO2012148930A2 (en) | 2011-04-26 | 2012-11-01 | Retrotope, Inc. | Oxidative retinal diseases |
| WO2013130422A1 (en) * | 2012-02-27 | 2013-09-06 | Biovista, Inc. | Compositions and methods for treating mitochondrial diseases |
| BR112015019564A2 (pt) * | 2013-02-15 | 2017-07-18 | Teva Pharma | tratamento de esclerose múltipla com laquinimod |
| KR101521807B1 (ko) * | 2014-01-20 | 2015-05-20 | 한국전자통신연구원 | 데이터 전송 제어 장치 및 그 방법 |
| SMT202400359T1 (it) * | 2014-05-09 | 2024-11-15 | Tecnimede Sociedade Tecnico Medicinal S | Sali mandelati degli enantiomeri del pirlindolo per l'uso in medicina |
| EP3950649A1 (en) | 2015-11-23 | 2022-02-09 | Retrotope, Inc. | Site-specific isotopic labeling of 1, 4-diene systems |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| CN109982712A (zh) | 2016-08-31 | 2019-07-05 | Mapi医药公司 | 包含醋酸格拉替雷的储库系统 |
| CN110382052A (zh) | 2017-03-26 | 2019-10-25 | Mapi医药公司 | 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统 |
| EP3520803A1 (en) * | 2018-01-31 | 2019-08-07 | Zarodex Therapeutics Limited | Novel uses |
| IL295783B2 (en) | 2020-02-21 | 2026-03-01 | Retrotope Inc | Processes for isotopic alteration of polyunsaturated fatty acids and their derivatives |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959470A (en) * | 1972-11-28 | 1976-05-25 | Mikhail Davidovich Mashkovsky | Psychotropic medicinal preparation |
| US5300645A (en) * | 1993-04-14 | 1994-04-05 | Eli Lilly And Company | Tetrahydro-pyrido-indole |
| US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| WO2004098638A1 (ja) * | 2003-05-06 | 2004-11-18 | Ono Pharmaceutical Co., Ltd. | エフェクター細胞機能阻害剤 |
| RU2281085C2 (ru) * | 2004-05-25 | 2006-08-10 | Закрытое акционерное общество "Мастерлек" | Антидепрессивные лекарственные средства для парентерального применения на основе сульфонатных солей пирлиндола |
| EP1688161A1 (en) * | 2004-11-02 | 2006-08-09 | Switch Biotech Aktiengesellschaft | Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis |
| KR20080034171A (ko) * | 2005-07-28 | 2008-04-18 | 브리스톨-마이어스 스큅 컴퍼니 | 세로토닌 수용체 효능제 및 길항제로서의 치환된테트라히드로-1h-피리도[4,3,b]인돌 |
| MX2009012788A (es) * | 2007-05-25 | 2010-01-14 | Medivation Neurology Inc | Metodos y composiciones para estimular celulas. |
-
2009
- 2009-12-11 US US13/133,553 patent/US20110268699A1/en not_active Abandoned
- 2009-12-11 EP EP09832613.5A patent/EP2375900B1/en not_active Not-in-force
- 2009-12-11 CN CN200980154585XA patent/CN102395275A/zh active Pending
- 2009-12-11 CA CA2747235A patent/CA2747235C/en active Active
- 2009-12-11 BR BRPI0922871A patent/BRPI0922871A2/pt not_active Application Discontinuation
- 2009-12-11 JP JP2011540922A patent/JP2012512165A/ja active Pending
- 2009-12-11 WO PCT/US2009/067673 patent/WO2010068867A1/en not_active Ceased
- 2009-12-11 AU AU2009324495A patent/AU2009324495B2/en not_active Ceased
-
2011
- 2011-06-12 IL IL213476A patent/IL213476A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0922871A2 (pt) | 2016-11-16 |
| JP2012512165A (ja) | 2012-05-31 |
| AU2009324495B2 (en) | 2015-12-24 |
| EP2375900A1 (en) | 2011-10-19 |
| US20110268699A1 (en) | 2011-11-03 |
| CA2747235A1 (en) | 2010-06-17 |
| CA2747235C (en) | 2021-02-09 |
| EP2375900B1 (en) | 2016-03-02 |
| CN102395275A (zh) | 2012-03-28 |
| EP2375900A4 (en) | 2012-05-02 |
| WO2010068867A1 (en) | 2010-06-17 |
| AU2009324495A1 (en) | 2011-07-28 |
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