IL213476A0 - Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles - Google Patents
Methods for treating multiple sclerosis using tetracyclic pyrazinoindolesInfo
- Publication number
- IL213476A0 IL213476A0 IL213476A IL21347611A IL213476A0 IL 213476 A0 IL213476 A0 IL 213476A0 IL 213476 A IL213476 A IL 213476A IL 21347611 A IL21347611 A IL 21347611A IL 213476 A0 IL213476 A0 IL 213476A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- multiple sclerosis
- treating multiple
- tetracyclic pyrazinoindoles
- pyrazinoindoles
- Prior art date
Links
- QKEBGAUJUHZNNU-UHFFFAOYSA-N 9h-pyrrolo[2,3-f]quinoxaline Chemical class N1=CC=NC2=C(NC=C3)C3=CC=C21 QKEBGAUJUHZNNU-UHFFFAOYSA-N 0.000 title 1
- 201000006417 multiple sclerosis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12157408P | 2008-12-11 | 2008-12-11 | |
| US23323509P | 2009-08-12 | 2009-08-12 | |
| PCT/US2009/067673 WO2010068867A1 (en) | 2008-12-11 | 2009-12-11 | Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL213476A0 true IL213476A0 (en) | 2011-07-31 |
Family
ID=42243090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL213476A IL213476A0 (en) | 2008-12-11 | 2011-06-12 | Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20110268699A1 (https=) |
| EP (1) | EP2375900B1 (https=) |
| JP (1) | JP2012512165A (https=) |
| CN (1) | CN102395275A (https=) |
| AU (1) | AU2009324495B2 (https=) |
| BR (1) | BRPI0922871A2 (https=) |
| CA (1) | CA2747235C (https=) |
| IL (1) | IL213476A0 (https=) |
| WO (1) | WO2010068867A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010031054A1 (en) | 2008-09-15 | 2010-03-18 | Biovista, Inc. | Compositions and methods for treating epilepsy |
| CA2777827C (en) | 2009-10-30 | 2020-08-18 | Retrotope, Inc. | Alleviating oxidative stress disorders with pufa derivatives |
| RU2436786C1 (ru) * | 2010-07-23 | 2011-12-20 | Александр Васильевич Иващенко | Замещенные индолы, противовирусный активный компонент, способ получения и применения |
| AU2012249920B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Disorders implicating PUFA oxidation |
| AU2012249917B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| EP3689342A1 (en) | 2011-04-26 | 2020-08-05 | Retrotope, Inc. | Oxidative retinal diseases |
| AU2012249918B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Impaired energy processing disorders and mitochondrial deficiency |
| WO2013130422A1 (en) * | 2012-02-27 | 2013-09-06 | Biovista, Inc. | Compositions and methods for treating mitochondrial diseases |
| EA201591507A1 (ru) * | 2013-02-15 | 2015-12-30 | Тева Фармасьютикал Индастриз Лтд. | Лечение рассеянного склероза лахинимодом |
| KR101521807B1 (ko) * | 2014-01-20 | 2015-05-20 | 한국전자통신연구원 | 데이터 전송 제어 장치 및 그 방법 |
| HRP20241165T1 (hr) * | 2014-05-09 | 2024-11-22 | Tecnimede Sociedade Tecnico-Medicinal S.A. | Mandelatne soli enantiomera pirlindola za upotrebu u medicini |
| CA3005983A1 (en) | 2015-11-23 | 2017-06-01 | Retrotope, Inc. | Site-specific isotopic labeling of 1,4-diene systems |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| HUE071047T2 (hu) | 2016-08-31 | 2025-07-28 | Mapi Pharma Ltd | Glatiramer-acetátot tartalmazó depórendszerek |
| CN110382052A (zh) | 2017-03-26 | 2019-10-25 | Mapi医药公司 | 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统 |
| EP3520803A1 (en) * | 2018-01-31 | 2019-08-07 | Zarodex Therapeutics Limited | Novel uses |
| CA3172351A1 (en) | 2020-02-21 | 2021-08-26 | Retrotope, Inc. | Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959470A (en) * | 1972-11-28 | 1976-05-25 | Mikhail Davidovich Mashkovsky | Psychotropic medicinal preparation |
| US5300645A (en) * | 1993-04-14 | 1994-04-05 | Eli Lilly And Company | Tetrahydro-pyrido-indole |
| US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| US20070270429A1 (en) * | 2003-05-06 | 2007-11-22 | Shiro Shibayama | Function Inhibitor of Effector Cell |
| RU2281085C2 (ru) * | 2004-05-25 | 2006-08-10 | Закрытое акционерное общество "Мастерлек" | Антидепрессивные лекарственные средства для парентерального применения на основе сульфонатных солей пирлиндола |
| EP1688161A1 (en) * | 2004-11-02 | 2006-08-09 | Switch Biotech Aktiengesellschaft | Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis |
| CA2617102A1 (en) * | 2005-07-28 | 2007-02-08 | Bristol-Myers Squibb Company | Substituted tetrahydro-1h-pyrido[4,3,b]indoles as serotonin receptor agonists and antagonists |
| JP2010528016A (ja) * | 2007-05-25 | 2010-08-19 | メディベーション ニューロロジー， インコーポレイテッド | 細胞を刺激するための方法および組成物 |
-
2009
- 2009-12-11 JP JP2011540922A patent/JP2012512165A/ja active Pending
- 2009-12-11 EP EP09832613.5A patent/EP2375900B1/en not_active Not-in-force
- 2009-12-11 BR BRPI0922871A patent/BRPI0922871A2/pt not_active Application Discontinuation
- 2009-12-11 WO PCT/US2009/067673 patent/WO2010068867A1/en not_active Ceased
- 2009-12-11 CN CN200980154585XA patent/CN102395275A/zh active Pending
- 2009-12-11 US US13/133,553 patent/US20110268699A1/en not_active Abandoned
- 2009-12-11 CA CA2747235A patent/CA2747235C/en active Active
- 2009-12-11 AU AU2009324495A patent/AU2009324495B2/en not_active Ceased
-
2011
- 2011-06-12 IL IL213476A patent/IL213476A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2375900A4 (en) | 2012-05-02 |
| EP2375900A1 (en) | 2011-10-19 |
| EP2375900B1 (en) | 2016-03-02 |
| US20110268699A1 (en) | 2011-11-03 |
| AU2009324495B2 (en) | 2015-12-24 |
| CA2747235C (en) | 2021-02-09 |
| WO2010068867A1 (en) | 2010-06-17 |
| AU2009324495A1 (en) | 2011-07-28 |
| BRPI0922871A2 (pt) | 2016-11-16 |
| CN102395275A (zh) | 2012-03-28 |
| CA2747235A1 (en) | 2010-06-17 |
| JP2012512165A (ja) | 2012-05-31 |
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