IL212275A0 - Synthetic mimetics of host defense and uses thereof - Google Patents
Synthetic mimetics of host defense and uses thereofInfo
- Publication number
- IL212275A0 IL212275A0 IL212275A IL21227511A IL212275A0 IL 212275 A0 IL212275 A0 IL 212275A0 IL 212275 A IL212275 A IL 212275A IL 21227511 A IL21227511 A IL 21227511A IL 212275 A0 IL212275 A0 IL 212275A0
- Authority
- IL
- Israel
- Prior art keywords
- host defense
- synthetic mimetics
- mimetics
- synthetic
- defense
- Prior art date
Links
- 230000007123 defense Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10859508P | 2008-10-27 | 2008-10-27 | |
| US12/605,584 US8278309B2 (en) | 2008-10-27 | 2009-10-26 | Synthetic mimetics of host defense and uses thereof |
| PCT/US2009/062147 WO2010062573A1 (en) | 2008-10-27 | 2009-10-27 | Synthetic mimetics of host defense and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL212275A0 true IL212275A0 (en) | 2011-06-30 |
Family
ID=42118100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL212275A IL212275A0 (en) | 2008-10-27 | 2011-04-12 | Synthetic mimetics of host defense and uses thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8278309B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2358380A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2012506908A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20110074995A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102256614B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009320139B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0920251A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2741764A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL212275A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2011004360A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2540077C2 (cg-RX-API-DMAC7.html) |
| TW (1) | TWI478915B (cg-RX-API-DMAC7.html) |
| UA (1) | UA104875C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010062573A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090092574A1 (en) | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
| US8278309B2 (en) * | 2008-10-27 | 2012-10-02 | Polymedix, Inc. | Synthetic mimetics of host defense and uses thereof |
| RU2606128C2 (ru) | 2011-05-16 | 2017-01-10 | Селлсьютикс Корпорейшн | Соединения для применения в лечении мукозита |
| US9758607B2 (en) | 2013-10-10 | 2017-09-12 | Research Foundation Of The City University Of New York | Polymer with antibacterial activity |
| JP6047203B2 (ja) * | 2015-02-20 | 2016-12-21 | セルセウティックス コーポレイション | 消化管の炎症性疾患の予防および／または治療のための宿主防御タンパク質（ｈｄｐ）模倣薬 |
| CN107574581B (zh) * | 2017-08-03 | 2019-09-10 | 天津大学 | 一种抗菌性聚(ε-己内酯)/模拟抗菌肽电纺纤维膜及其制备方法 |
| WO2021209563A1 (en) | 2020-04-16 | 2021-10-21 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus |
| US11771694B2 (en) | 2020-06-05 | 2023-10-03 | Innovation Pharmaceuticals Inc. | Arylamide compounds for treatment and prevention of viral infections |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496179A (en) | 1967-10-11 | 1970-02-17 | Pfizer & Co C | 2-amino-3,4-dihydroquinazolines |
| CA2128612C (en) | 1992-01-23 | 1999-06-15 | Mamoru Tomita | Antimicrobial agents and method for treating products therewith |
| JP2003523927A (ja) | 1998-08-20 | 2003-08-12 | ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | ジカチオンジベンゾフランおよびジベンゾチオフェン化合物並びにその使用法 |
| US6482799B1 (en) | 1999-05-25 | 2002-11-19 | The Regents Of The University Of California | Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial |
| JP2001261674A (ja) | 2000-03-22 | 2001-09-26 | Mitsui Chemicals Inc | ベンゾチオフェン誘導体およびそれを有効成分として含有する核内レセプター作動薬 |
| FR2813080B1 (fr) | 2000-08-17 | 2002-11-29 | Stago Diagnostica | Peptides anti-heparine |
| JP2004525865A (ja) | 2000-11-08 | 2004-08-26 | バイオ−コンセプト・ラボラトリーズ | 過酸化物源およびカチオン性ポリマー防腐剤を含有する改良した眼科用およびコンタクトレンズ用溶液 |
| CA2789997A1 (en) | 2001-03-08 | 2002-12-19 | William F. Degrado | Facially amphiphilic polymers an anti-infective agents |
| JP2005514368A (ja) * | 2001-11-21 | 2005-05-19 | スージェン・インコーポレーテッド | インドリノン誘導体を含む医薬製剤 |
| WO2003100701A1 (en) | 2002-05-28 | 2003-12-04 | The Trustees Of The University Of Pennsylvania | Methods, systems, and computer program products for computational analysis and design of amphiphilic polymers |
| US8234074B2 (en) | 2002-06-13 | 2012-07-31 | The Trustees Of The University Of Pennsylvania | Methods, systems, and computer program products for simulating biomembrances using coarse grain models |
| EP2471525A3 (en) | 2003-03-17 | 2012-12-12 | The Trustees Of The University Of Pennsylvania | Facially amphiphllic polymers and oligomers and uses thereof |
| AU2003249114A1 (en) | 2003-03-20 | 2004-10-11 | Shiseido International France | Cosmetic composition |
| US20050065091A1 (en) | 2003-09-18 | 2005-03-24 | Gholam Peyman | Stabilized ocular solutions |
| TWI388280B (zh) | 2004-01-23 | 2013-03-11 | Univ Pennsylvania | 面上兩性之聚芳基和聚芳炔基聚合物與寡聚物及其用途 |
| DK3520779T3 (da) * | 2004-04-23 | 2022-03-21 | Cydex Pharmaceuticals Inc | DPI formulering indeholdende sulfoalkylethercyclodextrin |
| CN102653515A (zh) | 2004-06-15 | 2012-09-05 | 宝利麦迪克斯股份有限公司 | 聚阳离子化合物及其用途 |
| WO2006132647A2 (en) | 2004-07-23 | 2006-12-14 | The Trustees Of The University Of Pennsylvania | Antimicrobial copolymers and uses thereof |
| NZ555501A (en) | 2004-11-24 | 2010-01-29 | Medpointe Healthcare Inc | Compositions comprising azelastine and methods of use thereof |
| WO2006067577A2 (en) | 2004-12-21 | 2006-06-29 | Pfizer Products Inc. | Stable non-dihydrate azithromycin oral suspensions |
| CA2599205A1 (en) | 2005-02-25 | 2006-09-08 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer |
| RU2325151C2 (ru) * | 2006-06-29 | 2008-05-27 | ООО "Научно-производственный центр "Амфион" | Способ получения системы доставки водонерастворимых и плохорастворимых биологически активных веществ и лекарственная форма на ее основе |
| JP2008137978A (ja) | 2006-12-05 | 2008-06-19 | Canon Inc | カルバゾール誘導体及びこれを用いた有機発光素子 |
| US20090092574A1 (en) * | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
| WO2009061697A1 (en) | 2007-11-09 | 2009-05-14 | The Board Of Trustees Of The University Of Illinois | Anticoagulant antagonist and hemophilia procoagulant |
| CN102164892A (zh) | 2008-07-28 | 2011-08-24 | 波利梅伊公司 | 抗疟疾化合物 |
| US8278309B2 (en) * | 2008-10-27 | 2012-10-02 | Polymedix, Inc. | Synthetic mimetics of host defense and uses thereof |
-
2009
- 2009-10-26 US US12/605,584 patent/US8278309B2/en not_active Expired - Fee Related
- 2009-10-26 TW TW098136112A patent/TWI478915B/zh active
- 2009-10-27 UA UAA201106679A patent/UA104875C2/uk unknown
- 2009-10-27 JP JP2011534666A patent/JP2012506908A/ja active Pending
- 2009-10-27 AU AU2009320139A patent/AU2009320139B2/en not_active Ceased
- 2009-10-27 CA CA2741764A patent/CA2741764A1/en not_active Abandoned
- 2009-10-27 BR BRPI0920251A patent/BRPI0920251A2/pt not_active IP Right Cessation
- 2009-10-27 MX MX2011004360A patent/MX2011004360A/es active IP Right Grant
- 2009-10-27 WO PCT/US2009/062147 patent/WO2010062573A1/en not_active Ceased
- 2009-10-27 KR KR1020117009356A patent/KR20110074995A/ko not_active Ceased
- 2009-10-27 CN CN200980151723.9A patent/CN102256614B/zh not_active Expired - Fee Related
- 2009-10-27 EP EP09829578A patent/EP2358380A4/en not_active Withdrawn
- 2009-10-27 RU RU2011121354/04A patent/RU2540077C2/ru not_active IP Right Cessation
-
2011
- 2011-04-12 IL IL212275A patent/IL212275A0/en unknown
-
2012
- 2012-08-01 US US13/563,928 patent/US8975262B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| RU2540077C2 (ru) | 2015-01-27 |
| RU2011121354A (ru) | 2012-12-10 |
| MX2011004360A (es) | 2011-08-12 |
| US20100105703A1 (en) | 2010-04-29 |
| TWI478915B (zh) | 2015-04-01 |
| WO2010062573A1 (en) | 2010-06-03 |
| EP2358380A1 (en) | 2011-08-24 |
| CN102256614A (zh) | 2011-11-23 |
| CA2741764A1 (en) | 2010-06-03 |
| CN102256614B (zh) | 2014-01-08 |
| JP2012506908A (ja) | 2012-03-22 |
| KR20110074995A (ko) | 2011-07-05 |
| TW201020249A (en) | 2010-06-01 |
| BRPI0920251A2 (pt) | 2016-01-05 |
| AU2009320139B2 (en) | 2013-07-25 |
| US8278309B2 (en) | 2012-10-02 |
| US8975262B2 (en) | 2015-03-10 |
| UA104875C2 (uk) | 2014-03-25 |
| US20130090345A1 (en) | 2013-04-11 |
| AU2009320139A1 (en) | 2010-06-03 |
| EP2358380A4 (en) | 2012-05-02 |
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