IL212171A - 1-Phenylpyrol compounds, pharmaceuticals containing them and their use - Google Patents
1-Phenylpyrol compounds, pharmaceuticals containing them and their useInfo
- Publication number
- IL212171A IL212171A IL212171A IL21217111A IL212171A IL 212171 A IL212171 A IL 212171A IL 212171 A IL212171 A IL 212171A IL 21217111 A IL21217111 A IL 21217111A IL 212171 A IL212171 A IL 212171A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- phenylpyrrole compounds
- phenylpyrrole
- compounds
- pharmaceutical
- Prior art date
Links
- 150000005356 1-phenylpyrroles Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/42—Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10380408P | 2008-10-08 | 2008-10-08 | |
| PCT/US2009/059852 WO2010042626A1 (en) | 2008-10-08 | 2009-10-07 | 1-phenylpyrrole compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL212171A0 IL212171A0 (en) | 2011-06-30 |
| IL212171A true IL212171A (en) | 2015-11-30 |
Family
ID=41328965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL212171A IL212171A (en) | 2008-10-08 | 2011-04-06 | 1-Phenylpyrol compounds, pharmaceuticals containing them and their use |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8642640B2 (Direct) |
| EP (1) | EP2349996B1 (Direct) |
| JP (2) | JP5767587B2 (Direct) |
| KR (1) | KR101671868B1 (Direct) |
| CN (1) | CN102177137B (Direct) |
| AU (1) | AU2009302375B2 (Direct) |
| BR (1) | BRPI0920551B1 (Direct) |
| CA (1) | CA2736930C (Direct) |
| ES (1) | ES2453500T3 (Direct) |
| IL (1) | IL212171A (Direct) |
| TW (2) | TWI532717B (Direct) |
| WO (1) | WO2010042626A1 (Direct) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8642640B2 (en) * | 2008-10-08 | 2014-02-04 | Exelixis, Inc. | 1-phenylpyrrole derivatives |
| CN104478781A (zh) * | 2015-01-13 | 2015-04-01 | 佛山市赛维斯医药科技有限公司 | 二烯金刚烷类化合物、其制备方法和用途 |
| CN104447484B (zh) * | 2015-01-13 | 2016-06-08 | 佛山市赛维斯医药科技有限公司 | 含烷氧苯基和二烯金刚烷结构的化合物、其制备方法和用途 |
| CN104447485A (zh) * | 2015-01-13 | 2015-03-25 | 佛山市赛维斯医药科技有限公司 | 一种含腈基苯和二烯金刚烷结构的化合物、其制备方法和用途 |
| CN104478782B (zh) * | 2015-01-13 | 2016-03-16 | 佛山市赛维斯医药科技有限公司 | 一类含烷氧苯基和二烯氟代金刚烷结构的化合物和用途 |
| CN112707854B (zh) | 2019-10-25 | 2022-03-15 | 年衍药业(珠海)有限公司 | 吡咯酰胺类化合物及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8026237B2 (en) * | 2004-07-30 | 2011-09-27 | Exelixis, Inc. | Pyrrole derivatives as pharmaceutical agents |
| ES2448498T3 (es) | 2007-04-09 | 2014-03-14 | Daiichi Sankyo Company, Limited | Atropisómero de derivado de pirrol |
| US8642640B2 (en) * | 2008-10-08 | 2014-02-04 | Exelixis, Inc. | 1-phenylpyrrole derivatives |
-
2009
- 2009-10-07 US US13/122,239 patent/US8642640B2/en active Active
- 2009-10-07 JP JP2011531142A patent/JP5767587B2/ja active Active
- 2009-10-07 AU AU2009302375A patent/AU2009302375B2/en not_active Ceased
- 2009-10-07 WO PCT/US2009/059852 patent/WO2010042626A1/en not_active Ceased
- 2009-10-07 CA CA2736930A patent/CA2736930C/en active Active
- 2009-10-07 KR KR1020117010429A patent/KR101671868B1/ko active Active
- 2009-10-07 CN CN200980139825.9A patent/CN102177137B/zh active Active
- 2009-10-07 BR BRPI0920551-9A patent/BRPI0920551B1/pt active IP Right Grant
- 2009-10-07 ES ES09793339.4T patent/ES2453500T3/es active Active
- 2009-10-07 EP EP09793339.4A patent/EP2349996B1/en active Active
- 2009-10-08 TW TW103129290A patent/TWI532717B/zh active
- 2009-10-08 TW TW098134159A patent/TWI460161B/zh active
-
2011
- 2011-04-06 IL IL212171A patent/IL212171A/en active IP Right Grant
-
2014
- 2014-07-22 JP JP2014148863A patent/JP5837655B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL212171A0 (en) | 2011-06-30 |
| CA2736930A1 (en) | 2010-04-15 |
| ES2453500T3 (es) | 2014-04-08 |
| AU2009302375A1 (en) | 2010-04-15 |
| EP2349996B1 (en) | 2014-01-01 |
| EP2349996A1 (en) | 2011-08-03 |
| TWI532717B (zh) | 2016-05-11 |
| KR101671868B1 (ko) | 2016-11-03 |
| AU2009302375B2 (en) | 2015-03-26 |
| CN102177137B (zh) | 2015-03-18 |
| JP2012505226A (ja) | 2012-03-01 |
| JP5837655B2 (ja) | 2015-12-24 |
| TW201028376A (en) | 2010-08-01 |
| US20110263544A1 (en) | 2011-10-27 |
| KR20110091664A (ko) | 2011-08-12 |
| HK1155162A1 (en) | 2012-05-11 |
| BRPI0920551A2 (pt) | 2020-08-11 |
| TWI460161B (zh) | 2014-11-11 |
| JP5767587B2 (ja) | 2015-08-19 |
| BRPI0920551B1 (pt) | 2021-12-14 |
| TW201514144A (zh) | 2015-04-16 |
| WO2010042626A1 (en) | 2010-04-15 |
| CA2736930C (en) | 2016-11-22 |
| CN102177137A (zh) | 2011-09-07 |
| US8642640B2 (en) | 2014-02-04 |
| JP2014196366A (ja) | 2014-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL255097A0 (en) | Antimicrobial compounds, pharmaceutical preparations containing them and their uses | |
| HUS1800007I1 (hu) | Gyógyászati készítmény | |
| IL216254A (en) | Compounds, pharmaceutical compositions and their uses | |
| IL242999B (en) | Pyrazolopyrimidine compounds, pharmaceutical preparations containing them and their uses | |
| IL215799A (en) | Quinazolone compounds, pharmaceuticals containing them and their uses | |
| GB0814695D0 (en) | Pharmaceutical compositions | |
| IL228817A0 (en) | Pharmaceutical compounds | |
| EP2133095A4 (en) | PHARMACEUTICAL COMPOSITION | |
| EP2133094A4 (en) | PHARMACEUTICAL COMPOSITION | |
| PL2323623T3 (pl) | Kompozycje farmaceutyczne | |
| IL206808A (en) | Indolyl-pyridone history, their pharmaceutical preparations and their uses | |
| IL200125A0 (en) | Pharmaceutical composition | |
| IL213452A0 (en) | Phenylpyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof | |
| EP2224805A4 (en) | PHARMACEUTICAL COMPOSITION | |
| EP2224915A4 (en) | PHARMACEUTICAL COMPOSITIONS | |
| ZA201102715B (en) | Solid pharmaceutical composition | |
| IL208387A0 (en) | Pharmaceutical composition | |
| EP2224808A4 (en) | PHARMACEUTICAL COMPOSITION | |
| ZA201100871B (en) | Solid pharmaceutical composition | |
| ZA201006224B (en) | Pharmaceutical composition | |
| IL206487A0 (en) | Pharmaceutical compositions | |
| GB2464200B (en) | Pharmaceutical composition | |
| ZA201005316B (en) | 2-amino-2-phenyl-alkanol derivatives, their preparation and pharmaceutical compositions containing them | |
| IL205975A0 (en) | Pharmaceutical composition | |
| GB0817969D0 (en) | Pharmaceutical composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |