IL202286A0 - Therapeutic pyrazoloquinoline urea derivatives - Google Patents
Therapeutic pyrazoloquinoline urea derivativesInfo
- Publication number
- IL202286A0 IL202286A0 IL202286A IL20228609A IL202286A0 IL 202286 A0 IL202286 A0 IL 202286A0 IL 202286 A IL202286 A IL 202286A IL 20228609 A IL20228609 A IL 20228609A IL 202286 A0 IL202286 A0 IL 202286A0
- Authority
- IL
- Israel
- Prior art keywords
- urea derivatives
- pyrazoloquinoline
- therapeutic
- therapeutic pyrazoloquinoline
- urea
- Prior art date
Links
- PBUWKCRTSMWDRY-UHFFFAOYSA-N NC(N)=O.C1=CNC2=C3C=NN=C3C=CC2=C1 Chemical class NC(N)=O.C1=CNC2=C3C=NN=C3C=CC2=C1 PBUWKCRTSMWDRY-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94299207P | 2007-06-08 | 2007-06-08 | |
| PCT/US2008/066205 WO2008154442A1 (en) | 2007-06-08 | 2008-06-06 | Therapeutic pyrazoloquinoline urea derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL202286A0 true IL202286A0 (en) | 2010-06-16 |
Family
ID=40096439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL202286A IL202286A0 (en) | 2007-06-08 | 2009-11-23 | Therapeutic pyrazoloquinoline urea derivatives |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7863266B2 (OSRAM) |
| EP (1) | EP2164328B8 (OSRAM) |
| JP (1) | JP2010529144A (OSRAM) |
| KR (1) | KR20100038189A (OSRAM) |
| CN (1) | CN101686682A (OSRAM) |
| AU (1) | AU2008261888A1 (OSRAM) |
| BR (1) | BRPI0812347A2 (OSRAM) |
| CA (1) | CA2688405A1 (OSRAM) |
| ES (1) | ES2433566T3 (OSRAM) |
| IL (1) | IL202286A0 (OSRAM) |
| MX (1) | MX2009013205A (OSRAM) |
| WO (1) | WO2008154442A1 (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8927546B2 (en) * | 2006-02-28 | 2015-01-06 | Dart Neuroscience (Cayman) Ltd. | Therapeutic piperazines |
| MX2009013205A (es) * | 2007-06-08 | 2010-04-09 | Helicon Therapeutics Inc | Derivados de pirazoloquinolina urea terapeuticos. |
| WO2011049731A1 (en) | 2009-10-21 | 2011-04-28 | Merck Sharp & Dohme Corp. | Quinolinone-pyrazolone m1 receptor positive allosteric modulators |
| FR2962335B1 (fr) * | 2010-07-12 | 2013-01-18 | Cll Pharma | Utilisation du nonapeptide pat dans le traitement et la prevention des maladies neurodegeneratives |
| US9468662B2 (en) | 2010-07-12 | 2016-10-18 | Orphit | Use of the PAT nonapeptide in the treatment and prevention of neurodegenerative diseases |
| US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
| CN106187887B (zh) * | 2016-07-01 | 2018-08-14 | 上海工程技术大学 | 4-羟基喹啉-3-甲酸的制备方法 |
| ES2884073T3 (es) | 2016-11-11 | 2021-12-10 | Bayer Animal Health Gmbh | Nuevos derivados antihelmínticos de quinolina-3-carboxamida |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CY1357A (en) * | 1979-06-21 | 1987-08-07 | Ciba Geigy Ag | Pyrazolo-quinolines, processes for their production, pharmaceutical compositions containing them and their therapeutical use |
| DE3204126A1 (de) * | 1982-02-06 | 1983-08-11 | Bayer Ag, 5090 Leverkusen | Pyrazoloxazine, -thiazine, -chinoline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4524146A (en) * | 1982-12-08 | 1985-06-18 | Ciba-Geigy Corporation | Certain -2-heterocycle substituted pyrazoloquinolines |
| US4814450A (en) * | 1984-07-09 | 1989-03-21 | Ciba-Geigy Corporation | Certain ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives |
| JPS61112075A (ja) * | 1984-11-05 | 1986-05-30 | Shionogi & Co Ltd | チエニルピラゾロキノリン誘導体 |
| EP0214092A1 (en) | 1985-08-08 | 1987-03-11 | Ciba-Geigy Ag | Enhanced absorption of psychoactive 2-aryl-pyrazolo quinolines as a solid molecular dispersion in polyvinylpyrrolidone |
| CA2110942A1 (en) * | 1991-06-14 | 1992-12-23 | Pharmacia & Upjohn Company Llc | Imidazo¬1,5-a|quinoxalines |
| US5334595A (en) * | 1992-10-23 | 1994-08-02 | Sterling Winthrop Inc. | Pyrazoloquinolones as anticancer agents |
| US5792766A (en) * | 1996-03-13 | 1998-08-11 | Neurogen Corporation | Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands |
| GB9716345D0 (en) * | 1997-08-01 | 1997-10-08 | Merck Sharp & Dohme | Therapeutic compounds |
| GB9716347D0 (en) * | 1997-08-01 | 1997-10-08 | Merck Sharp & Dohme | Therapeutic compounds |
| GB9716344D0 (en) * | 1997-08-01 | 1997-10-08 | Merck Sharp & Dohme | Therapeutic compounds |
| TWI271406B (en) * | 1999-12-13 | 2007-01-21 | Eisai Co Ltd | Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same |
| HUP0303270A3 (en) * | 2001-02-21 | 2007-03-28 | Janssen Pharmaceutica Nv | Isoxazoline derivatives as anti-depressants, process for their preparation and pharmaceutical compositions containing them |
| JP3896309B2 (ja) * | 2001-07-09 | 2007-03-22 | ファイザー株式会社 | プロテインキナーゼｃ阻害物質としてのピラゾロキノリノン誘導体 |
| WO2004055014A1 (en) * | 2002-12-16 | 2004-07-01 | Active Biotech Ab | Tetracyclic immunomodulatory compounds |
| TW200508233A (en) * | 2003-05-29 | 2005-03-01 | Millennium Pharm Inc | Chk-1 inhibitors |
| US7544697B2 (en) * | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| EP1937236A2 (en) * | 2005-09-07 | 2008-07-02 | Braincells, Inc. | Modulation of neurogenesis by hdac inhibition |
| CN103936690B (zh) * | 2005-10-25 | 2016-06-08 | 盐野义制药株式会社 | 氨基二氢噻嗪衍生物 |
| CA2689934A1 (en) * | 2007-06-08 | 2008-12-18 | Helicon Therapeutics, Inc. | Therapeutic pyrazolonaphthyridine derivatives |
| ATE544344T1 (de) * | 2007-06-08 | 2012-02-15 | Helicon Therapeutics Inc | Therapeutische pyrazolochinolinderivate |
| MX2009013205A (es) * | 2007-06-08 | 2010-04-09 | Helicon Therapeutics Inc | Derivados de pirazoloquinolina urea terapeuticos. |
-
2008
- 2008-06-06 MX MX2009013205A patent/MX2009013205A/es active IP Right Grant
- 2008-06-06 WO PCT/US2008/066205 patent/WO2008154442A1/en not_active Ceased
- 2008-06-06 KR KR1020107000233A patent/KR20100038189A/ko not_active Withdrawn
- 2008-06-06 US US12/135,023 patent/US7863266B2/en not_active Expired - Fee Related
- 2008-06-06 AU AU2008261888A patent/AU2008261888A1/en not_active Abandoned
- 2008-06-06 EP EP08770406.0A patent/EP2164328B8/en not_active Not-in-force
- 2008-06-06 CA CA002688405A patent/CA2688405A1/en not_active Abandoned
- 2008-06-06 JP JP2010511389A patent/JP2010529144A/ja active Pending
- 2008-06-06 ES ES08770406T patent/ES2433566T3/es active Active
- 2008-06-06 CN CN200880023876A patent/CN101686682A/zh active Pending
- 2008-06-06 BR BRPI0812347A patent/BRPI0812347A2/pt not_active IP Right Cessation
-
2009
- 2009-11-23 IL IL202286A patent/IL202286A0/en unknown
-
2010
- 2010-11-29 US US12/955,792 patent/US8343957B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2164328A4 (en) | 2010-06-23 |
| MX2009013205A (es) | 2010-04-09 |
| US20110071140A1 (en) | 2011-03-24 |
| BRPI0812347A2 (pt) | 2016-08-02 |
| US8343957B2 (en) | 2013-01-01 |
| ES2433566T3 (es) | 2013-12-11 |
| JP2010529144A (ja) | 2010-08-26 |
| EP2164328B8 (en) | 2013-09-11 |
| CN101686682A (zh) | 2010-03-31 |
| US20080306048A1 (en) | 2008-12-11 |
| CA2688405A1 (en) | 2008-12-18 |
| AU2008261888A1 (en) | 2008-12-18 |
| US7863266B2 (en) | 2011-01-04 |
| KR20100038189A (ko) | 2010-04-13 |
| EP2164328A1 (en) | 2010-03-24 |
| WO2008154442A1 (en) | 2008-12-18 |
| EP2164328B1 (en) | 2013-08-07 |
| HK1142496A1 (en) | 2010-12-10 |
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