IL201253A0 - A transition metal catalyzed synthesis of n - aminoindoles - Google Patents
A transition metal catalyzed synthesis of n - aminoindolesInfo
- Publication number
- IL201253A0 IL201253A0 IL201253A IL20125309A IL201253A0 IL 201253 A0 IL201253 A0 IL 201253A0 IL 201253 A IL201253 A IL 201253A IL 20125309 A IL20125309 A IL 20125309A IL 201253 A0 IL201253 A0 IL 201253A0
- Authority
- IL
- Israel
- Prior art keywords
- transition metal
- metal catalyzed
- aminoindoles
- formula
- catalyzed synthesis
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 229910052723 transition metal Inorganic materials 0.000 title abstract 2
- 150000003624 transition metals Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- HDIJHZHDOMXSQS-UHFFFAOYSA-N 2-ethynylbenzenesulfonic acid Chemical class OS(=O)(=O)C1=CC=CC=C1C#C HDIJHZHDOMXSQS-UHFFFAOYSA-N 0.000 abstract 1
- -1 N,N-disubstituted hydrazines Chemical class 0.000 abstract 1
- 230000000895 acaricidal effect Effects 0.000 abstract 1
- 239000000642 acaricide Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000855 fungicidal effect Effects 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- ZWUUZXDACSQYMI-UHFFFAOYSA-N indazol-1-amine Chemical class C1=CC=C2N(N)N=CC2=C1 ZWUUZXDACSQYMI-UHFFFAOYSA-N 0.000 abstract 1
- VUSYGSNEEYEGGX-UHFFFAOYSA-N indol-1-amine Chemical compound C1=CC=C2N(N)C=CC2=C1 VUSYGSNEEYEGGX-UHFFFAOYSA-N 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 239000004973 liquid crystal related substance Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000001069 nematicidal effect Effects 0.000 abstract 1
- 230000000590 parasiticidal effect Effects 0.000 abstract 1
- 239000002297 parasiticide Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07007585 | 2007-04-13 | ||
| PCT/EP2008/002519 WO2008125207A1 (en) | 2007-04-13 | 2008-03-29 | A transition metal catalyzed synthesis of n-aminoindoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL201253A0 true IL201253A0 (en) | 2010-05-31 |
Family
ID=38457866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL201253A IL201253A0 (en) | 2007-04-13 | 2009-09-30 | A transition metal catalyzed synthesis of n - aminoindoles |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8026375B2 (https=) |
| EP (1) | EP2134682B1 (https=) |
| JP (1) | JP5412422B2 (https=) |
| KR (1) | KR20100015546A (https=) |
| CN (1) | CN101657422A (https=) |
| AT (1) | ATE537142T1 (https=) |
| AU (1) | AU2008238379A1 (https=) |
| BR (1) | BRPI0810199A2 (https=) |
| CA (1) | CA2683578A1 (https=) |
| IL (1) | IL201253A0 (https=) |
| MX (1) | MX2009010536A (https=) |
| WO (1) | WO2008125207A1 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9512125B2 (en) | 2004-11-19 | 2016-12-06 | The Regents Of The University Of California | Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents |
| WO2007114926A2 (en) | 2006-04-04 | 2007-10-11 | The Regents Of The University Of California | Kinase antagonists |
| GB2467670B (en) | 2007-10-04 | 2012-08-01 | Intellikine Inc | Chemical entities and therapeutic uses thereof |
| EP3613743B1 (en) | 2008-01-04 | 2022-03-16 | Intellikine, LLC | Processes for the preparation of 1h-pyrazolo[3,4-d]pyrimidin-4-amine derivatives |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| US8637542B2 (en) | 2008-03-14 | 2014-01-28 | Intellikine, Inc. | Kinase inhibitors and methods of use |
| US8993580B2 (en) | 2008-03-14 | 2015-03-31 | Intellikine Llc | Benzothiazole kinase inhibitors and methods of use |
| US20110224223A1 (en) | 2008-07-08 | 2011-09-15 | The Regents Of The University Of California, A California Corporation | MTOR Modulators and Uses Thereof |
| JP5788316B2 (ja) | 2008-07-08 | 2015-09-30 | インテリカイン， エルエルシー | キナーゼインヒビターおよび使用方法 |
| US8703778B2 (en) | 2008-09-26 | 2014-04-22 | Intellikine Llc | Heterocyclic kinase inhibitors |
| WO2010045542A2 (en) | 2008-10-16 | 2010-04-22 | The Regents Of The University Of California | Fused ring heteroaryl kinase inhibitors |
| US8476431B2 (en) | 2008-11-03 | 2013-07-02 | Itellikine LLC | Benzoxazole kinase inhibitors and methods of use |
| EP2427195B1 (en) | 2009-05-07 | 2019-05-01 | Intellikine, LLC | Heterocyclic compounds and uses thereof |
| US8980899B2 (en) | 2009-10-16 | 2015-03-17 | The Regents Of The University Of California | Methods of inhibiting Ire1 |
| CA2799579A1 (en) | 2010-05-21 | 2011-11-24 | Intellikine, Inc. | Chemical compounds, compositions and methods for kinase modulation |
| JP2013545749A (ja) | 2010-11-10 | 2013-12-26 | インフィニティー ファーマシューティカルズ， インコーポレイテッド | 複素環化合物及びその使用 |
| TWI674262B (zh) | 2011-01-10 | 2019-10-11 | 美商英菲尼提製藥股份有限公司 | 製備異喹啉酮之方法及異喹啉酮之固體形式 |
| CN102093334B (zh) * | 2011-02-22 | 2013-05-08 | 郑州大学 | 一组稠环噻吩类化合物的合成方法 |
| US9295673B2 (en) | 2011-02-23 | 2016-03-29 | Intellikine Llc | Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof |
| WO2013012915A1 (en) | 2011-07-19 | 2013-01-24 | Infinity Pharmaceuticals Inc. | Heterocyclic compounds and uses thereof |
| MX2014000648A (es) | 2011-07-19 | 2014-09-25 | Infinity Pharmaceuticals Inc | Compuestos heterociclicos y sus usos. |
| KR20140075693A (ko) | 2011-08-29 | 2014-06-19 | 인피니티 파마슈티칼스, 인코포레이티드 | 헤테로사이클릭 화합물 및 그의 용도 |
| MX370814B (es) | 2011-09-02 | 2020-01-08 | Univ California | Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas. |
| US8940742B2 (en) | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| MX2015003874A (es) | 2012-09-26 | 2015-12-16 | Univ California | Modulacion de ire1. |
| EP2914296B2 (en) | 2012-11-01 | 2021-09-29 | Infinity Pharmaceuticals, Inc. | Treatment of cancers using pi3 kinase isoform modulators |
| US9481667B2 (en) | 2013-03-15 | 2016-11-01 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| MX2021012208A (es) | 2013-10-04 | 2023-01-19 | Infinity Pharmaceuticals Inc | Compuestos heterocíclicos y usos de los mismos. |
| WO2015051241A1 (en) | 2013-10-04 | 2015-04-09 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| CN103755621B (zh) * | 2014-01-23 | 2015-08-05 | 清华大学 | 由芳基肼和炔烃制备多取代吲哚的方法 |
| NZ724368A (en) | 2014-03-19 | 2023-07-28 | Infinity Pharmaceuticals Inc | Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders |
| WO2015160975A2 (en) | 2014-04-16 | 2015-10-22 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| WO2016054491A1 (en) | 2014-10-03 | 2016-04-07 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| WO2016069796A1 (en) * | 2014-10-28 | 2016-05-06 | Spectrum Spine Ip Holdings, Llc | Expandable, adjustable inter-body fusion devices and methods |
| EP4585268A3 (en) | 2015-09-14 | 2025-10-15 | Twelve Therapeutics, Inc. | Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same |
| US10759806B2 (en) | 2016-03-17 | 2020-09-01 | Infinity Pharmaceuticals, Inc. | Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors |
| WO2017214269A1 (en) | 2016-06-08 | 2017-12-14 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| RU2754507C2 (ru) | 2016-06-24 | 2021-09-02 | Инфинити Фармасьютикалз, Инк. | Комбинированная терапия |
| KR102038977B1 (ko) * | 2016-12-30 | 2019-11-01 | 사빅 에스케이 넥슬렌 컴퍼니 피티이 엘티디 | 신규한 시클로펜타[ｂ]티오펜일 전이금속 화합물, 이를 포함하는 전이금속 촉매 조성물, 및 이를 이용한 에틸렌 단독중합체 또는 에틸렌과 α-올레핀의 공중합체의 제조방법 |
| ES2974634T3 (es) | 2018-12-21 | 2024-06-28 | Celgene Corp | Inhibidores de tienopiridinas de RIPK2 |
| CN121021734A (zh) * | 2018-12-21 | 2025-11-28 | 陶氏环球技术有限责任公司 | 用于烯烃聚合的基于杂环-杂环的iv族过渡金属催化剂 |
| CN116813522A (zh) * | 2023-05-04 | 2023-09-29 | 广州方中化工有限公司 | 一种含吲哚的苯磺酰脲类化合物的制备方法与应用 |
| CN118638038B (zh) * | 2024-06-05 | 2024-12-03 | 常州大学 | 一种n-n轴手性吲哚酰胺类化合物及其合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE115143T1 (de) * | 1987-04-24 | 1994-12-15 | Hoechst Roussel Pharma | N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel. |
| US4983608A (en) | 1989-09-05 | 1991-01-08 | Hoechst-Roussell Pharmaceuticals, Inc. | N-substituted-4-pyrimidinamines and pyrimidinediamines |
| DE60016068T2 (de) | 1999-03-10 | 2005-11-03 | Tosoh Corp., Shinnanyo | Verfahren zur Herstellung Stickstoffheterocyclischer Verbindungen |
| FR2842196B1 (fr) * | 2002-07-15 | 2006-01-13 | Rhodia Polyamide Intermediates | Procede de fabrication de composes nitriles a partir de composes a insaturation ethylenique |
| EP2119455A1 (en) | 2004-04-08 | 2009-11-18 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Tripartite raftophilic structures and their use |
-
2008
- 2008-03-29 WO PCT/EP2008/002519 patent/WO2008125207A1/en not_active Ceased
- 2008-03-29 AU AU2008238379A patent/AU2008238379A1/en not_active Abandoned
- 2008-03-29 BR BRPI0810199-0A2A patent/BRPI0810199A2/pt not_active IP Right Cessation
- 2008-03-29 KR KR1020097021379A patent/KR20100015546A/ko not_active Withdrawn
- 2008-03-29 CA CA002683578A patent/CA2683578A1/en not_active Abandoned
- 2008-03-29 AT AT08734883T patent/ATE537142T1/de active
- 2008-03-29 CN CN200880011689A patent/CN101657422A/zh active Pending
- 2008-03-29 MX MX2009010536A patent/MX2009010536A/es active IP Right Grant
- 2008-03-29 JP JP2010502442A patent/JP5412422B2/ja not_active Expired - Fee Related
- 2008-03-29 EP EP08734883A patent/EP2134682B1/en not_active Not-in-force
-
2009
- 2009-09-30 IL IL201253A patent/IL201253A0/en unknown
- 2009-10-09 US US12/576,339 patent/US8026375B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE537142T1 (de) | 2011-12-15 |
| WO2008125207A1 (en) | 2008-10-23 |
| AU2008238379A1 (en) | 2008-10-23 |
| KR20100015546A (ko) | 2010-02-12 |
| CN101657422A (zh) | 2010-02-24 |
| CA2683578A1 (en) | 2008-10-23 |
| US20100168429A1 (en) | 2010-07-01 |
| MX2009010536A (es) | 2009-10-22 |
| JP5412422B2 (ja) | 2014-02-12 |
| EP2134682B1 (en) | 2011-12-14 |
| JP2010523605A (ja) | 2010-07-15 |
| BRPI0810199A2 (pt) | 2014-10-14 |
| US8026375B2 (en) | 2011-09-27 |
| EP2134682A1 (en) | 2009-12-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL201253A0 (en) | A transition metal catalyzed synthesis of n - aminoindoles | |
| MX2009014203A (es) | Una sintesis de 2h-indazoles catalizada por un metal de transicion. | |
| MX2009013753A (es) | Una sintesis regioselectiva catalizada por cobre de bencimidazoles y azabencimidazoles. | |
| IL196431A0 (en) | A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | |
| MX2009007713A (es) | Derivados de piridazina, procedimientos para su preparacion y su uso como fungicidas. | |
| TW200617009A (en) | Organic compounds | |
| TW200732335A (en) | Organic compounds | |
| MX2008000255A (es) | Activadores de urea glucocinasa. | |
| MY150379A (en) | Fused heterocyclic derivative and use thereof | |
| WO2010053583A3 (en) | Small molecule cd4 mimetics and uses thereof | |
| MX2009013738A (es) | Un procedimiento catalizado por paladio para el acoplamiento de alquinos terminales con tosilatos de arilo. | |
| TW200635921A (en) | Organic compounds | |
| TW200638930A (en) | Acetylene derivatives | |
| GB0508318D0 (en) | Organic compounds | |
| WO2006108572A3 (en) | Novel crystalline pharmaceutical product | |
| TW200732337A (en) | Organic compounds | |
| WO2008136378A1 (ja) | 新規なスルホンアミド誘導体またはその塩 | |
| WO2007065684A3 (en) | Bicyclic heteroyclic compounds as antiinflammatory or antiallergic agents | |
| TN2010000094A1 (en) | Novel herbicides | |
| WO2008156102A1 (ja) | ピラゾロン誘導体及びそれらを有効成分とするｐｄｅ阻害剤 | |
| TW200744996A (en) | Improved process for the production of nitroisourea derivative | |
| MY151461A (en) | A process for the palladium-catalyzed coupling of terminal alkynes with heteroayl tosylates and heteroaryl benzenesulfonates | |
| TW200716521A (en) | Substituted aryl oximes | |
| UA94827C2 (ru) | Нафталиновые соединения, способ их получения и фармацевтическая композиция, которая их содержит | |
| IL182557A0 (en) | Process for the preparation of phenyl 2-pyrimidinyl ketones and their novel intermediates |