IL198526A - Spink1 as a prostate cancer marker and uses thereof - Google Patents
Spink1 as a prostate cancer marker and uses thereofInfo
- Publication number
- IL198526A IL198526A IL198526A IL19852609A IL198526A IL 198526 A IL198526 A IL 198526A IL 198526 A IL198526 A IL 198526A IL 19852609 A IL19852609 A IL 19852609A IL 198526 A IL198526 A IL 198526A
- Authority
- IL
- Israel
- Prior art keywords
- expression
- erg
- rna
- cancer
- sequence
- Prior art date
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8135—Kazal type inhibitors, e.g. pancreatic secretory inhibitor or ovomucoid
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| PCT/US2007/084090 WO2008058239A2 (en) | 2006-11-08 | 2007-11-08 | Spink1 as a prostate cancer marker and uses thereof |
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| WO (1) | WO2008058239A2 (OSRAM) |
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| US20110206697A1 (en) * | 2010-02-19 | 2011-08-25 | The Regents Of The University Of Michigan | Spink1 targeted therapy |
| JP2013524783A (ja) * | 2010-04-02 | 2013-06-20 | ベリデックス・エルエルシー | 限局性前立腺癌患者に対するｐｓａ再発の遺伝子に基づく予測 |
| US20140308657A1 (en) * | 2010-12-09 | 2014-10-16 | Philadelphia Health & Education Corporation D/B/A Drexel University College Of Medicine | Serine protease inhibitor kazal antibodies |
| EP4310198A3 (en) * | 2011-05-12 | 2024-04-24 | MDxHealth Research B.V. | Molecular markers in prostate cancer |
| EP3492606B1 (en) * | 2011-08-22 | 2023-10-04 | Exosome Diagnostics, Inc. | Urine biomarkers |
| WO2013036755A1 (en) * | 2011-09-09 | 2013-03-14 | Sloan-Kettering Institute For Cancer Research | Etv1 antibodies and uses thereof |
| AU2012345926A1 (en) * | 2011-11-29 | 2014-05-29 | Genentech, Inc. | Compositions and methods for prostate cancer analysis |
| CN103436594A (zh) * | 2012-10-16 | 2013-12-11 | 科蒂亚(新乡)生物技术有限公司 | 一种bdna在尿液中检测pca3的应用 |
| CN102968558B (zh) * | 2012-11-14 | 2015-11-18 | 叶定伟 | 一种预测初诊前列腺癌骨转移风险的装置 |
| EP3227460B1 (en) * | 2014-12-01 | 2021-01-27 | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. | Novel rna-biomarker signature for diagnosis of prostate cancer |
| CN104531878B (zh) * | 2015-01-04 | 2017-11-10 | 上海市同济医院 | 一种联合lncRNA和AR3检测试剂盒及应用 |
| CN105717082A (zh) * | 2016-02-02 | 2016-06-29 | 管晓翔 | 一种用于检测三阴性乳腺癌瘤内异质性的方法 |
| KR101948385B1 (ko) * | 2016-09-01 | 2019-05-13 | 충북대학교 산학협력단 | 전립선암 예후 분석용 신규 바이오마커 및 그의 용도 |
| CN109521457B (zh) * | 2018-09-25 | 2022-10-21 | 中国辐射防护研究院 | 一种基于信息准则的γ辐射源项划分方法及系统 |
| CN111110849B (zh) * | 2018-10-11 | 2021-09-10 | 中国科学院上海营养与健康研究所 | 丝氨酸蛋白酶抑制因子Kazal 1型在制备细胞衰老及肿瘤诊断或调控制剂中的应用 |
| CN109776679B (zh) * | 2019-01-08 | 2022-06-17 | 灏灵赛奥（天津）生物科技有限公司 | 一种丝氨酸蛋白酶抑制因子spink1的抗体、其制备方法和应用 |
| CN109678950B (zh) * | 2019-01-08 | 2022-05-10 | 灏灵赛奥（天津）生物科技有限公司 | spink1抗原、能够特异性结合spink1的抗体及其功能片段及其应用和产品 |
| US12319967B2 (en) | 2019-08-21 | 2025-06-03 | University Of Virginia Patent Foundation | Methods and compositions for diagnosing and treating prostate cancer based on long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth |
| US11788091B2 (en) | 2019-08-21 | 2023-10-17 | University Of Virginia Patent Foundation | Methods and compositions for diagnosing and treating prostate cancer based on long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth |
| CN111308095A (zh) * | 2020-03-04 | 2020-06-19 | 北京师范大学 | 用于诊断前列腺癌的尿液蛋白标记物 |
| EP4232605A4 (en) * | 2020-11-11 | 2024-09-25 | University of Virginia Patent Foundation | METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING PROSTATE CANCER BASED ON LONG NON-CODING RNA OVERLAPPING THE LCK GENE REGULATING PROSTATE CANCER CELL GROWTH |
| JPWO2023276768A1 (OSRAM) * | 2021-06-29 | 2023-01-05 | ||
| CN115181801A (zh) * | 2022-07-11 | 2022-10-14 | 中山大学附属第一医院 | Bhlhe22在前列腺癌骨转移免疫治疗中的应用 |
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| US4323546A (en) * | 1978-05-22 | 1982-04-06 | Nuc Med Inc. | Method and composition for cancer detection in humans |
| JP3448090B2 (ja) * | 1994-02-16 | 2003-09-16 | 浜松ホトニクス株式会社 | エネルギー移動検出法およびその装置 |
| US20050214309A1 (en) * | 1994-03-18 | 2005-09-29 | Hinrichs Steven H | Methods and compositions for modulating transcription factor activity |
| US5854206A (en) * | 1995-08-25 | 1998-12-29 | Corixa Corporation | Compounds and methods for treatment and diagnosis of prostate cancer |
| KR19990087802A (ko) * | 1996-03-15 | 1999-12-27 | 길리스 스티브 | 전립선암의 면역치료 및 면역진단을 위한 화합물 및 방법 |
| US20030185830A1 (en) * | 1997-02-25 | 2003-10-02 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| CN1195851C (zh) * | 1997-02-25 | 2005-04-06 | 科里克萨有限公司 | 用于前列腺癌免疫疗法的化合物及其用途 |
| ES2324503T3 (es) * | 1997-04-10 | 2009-08-07 | Stichting Katholieke Universiteit University Medical Centre Nijmegen | Pca3, genes pca3 y metodos de uso. |
| US6187799B1 (en) * | 1997-05-23 | 2001-02-13 | Onyx Pharmaceuticals | Inhibition of raf kinase activity using aryl ureas |
| US6828429B1 (en) * | 1999-03-26 | 2004-12-07 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Prostate-specific gene, PCGEM1, and the methods of using PCGEM1 to detect, treat, and prevent prostate cancer |
| JP2004509882A (ja) * | 2000-09-21 | 2004-04-02 | スミスクライン ビーチャム パブリック リミテッド カンパニー | Ｒａｆキナーゼ阻害剤としてのイミダゾール誘導体 |
| US6897024B2 (en) * | 2001-05-31 | 2005-05-24 | Stichting Katholieke Universiteit More Particularly The University Medical Centre Nijmegen | Nucleic acid molecules comprising the promoter for PCA3, and uses thereof |
| US7229774B2 (en) * | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
| US7790867B2 (en) * | 2002-12-05 | 2010-09-07 | Rosetta Genomics Inc. | Vaccinia virus-related nucleic acids and microRNA |
| AU2004256425A1 (en) * | 2003-06-09 | 2005-01-20 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| ATE451477T1 (de) * | 2003-09-05 | 2009-12-15 | Univ Jefferson | Diagnose und überwachung von hepatozellulärem karzinom |
| JP2008509673A (ja) * | 2004-08-13 | 2008-04-03 | ミレニアム ファーマシューティカルズ， インコーポレイテッド | ヒト前立腺癌の同定、評価、予防および治療のための遺伝子、組成物、キットおよび方法 |
| US20060275794A1 (en) * | 2005-03-07 | 2006-12-07 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
| EP2612870A1 (en) * | 2005-09-12 | 2013-07-10 | The Regents of the University of Michigan | Recurrent gene fusions in prostate cancer |
| CA3018520C (en) * | 2006-10-10 | 2022-05-17 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Prostate cancer-specific alterations in erg gene expression and detection and treatment methods based on those alterations |
| WO2009044899A1 (ja) * | 2007-10-03 | 2009-04-09 | Kyowa Hakko Kirin Co., Ltd. | 細胞の増殖を制御する核酸 |
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2007
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2009
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2011
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2013
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Also Published As
| Publication number | Publication date |
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| JP2010508855A (ja) | 2010-03-25 |
| JP2014087335A (ja) | 2014-05-15 |
| IL215373A (en) | 2013-07-31 |
| WO2008058239A3 (en) | 2008-11-06 |
| IL215373A0 (en) | 2011-11-30 |
| CN101652484B (zh) | 2013-03-20 |
| US20100129804A1 (en) | 2010-05-27 |
| WO2008058239A9 (en) | 2009-12-23 |
| IL198526A0 (en) | 2010-02-17 |
| WO2008058239A2 (en) | 2008-05-15 |
| CN103233063A (zh) | 2013-08-07 |
| EP2079851B1 (en) | 2015-01-07 |
| CN101652484A (zh) | 2010-02-17 |
| AU2007317306A1 (en) | 2008-05-15 |
| EP2079851A2 (en) | 2009-07-22 |
| JP5850898B2 (ja) | 2016-02-03 |
| CA2668961A1 (en) | 2008-05-15 |
| AU2007317306B2 (en) | 2012-06-14 |
| EP2079851A4 (en) | 2010-09-01 |
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