IL193097A - Methods and kits for early diagnosis of cancer or predisposition to cancer - Google Patents

Methods and kits for early diagnosis of cancer or predisposition to cancer

Info

Publication number
IL193097A
IL193097A IL193097A IL19309708A IL193097A IL 193097 A IL193097 A IL 193097A IL 193097 A IL193097 A IL 193097A IL 19309708 A IL19309708 A IL 19309708A IL 193097 A IL193097 A IL 193097A
Authority
IL
Israel
Prior art keywords
cancer
sample
protein
dna
malignant
Prior art date
Application number
IL193097A
Other languages
English (en)
Hebrew (he)
Other versions
IL193097A0 (en
Inventor
Nadir Arber
Original Assignee
Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct
Nadir Arber
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct, Nadir Arber filed Critical Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct
Priority to IL193097A priority Critical patent/IL193097A/en
Publication of IL193097A0 publication Critical patent/IL193097A0/en
Publication of IL193097A publication Critical patent/IL193097A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57419Specifically defined cancers of colon
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL193097A 2006-01-31 2008-07-28 Methods and kits for early diagnosis of cancer or predisposition to cancer IL193097A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL193097A IL193097A (en) 2006-01-31 2008-07-28 Methods and kits for early diagnosis of cancer or predisposition to cancer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76337806P 2006-01-31 2006-01-31
PCT/IL2007/000122 WO2007088537A2 (en) 2006-01-31 2007-01-31 Methods and kits for early detection of cancer or predisposition thereto
IL193097A IL193097A (en) 2006-01-31 2008-07-28 Methods and kits for early diagnosis of cancer or predisposition to cancer

Publications (2)

Publication Number Publication Date
IL193097A0 IL193097A0 (en) 2009-02-11
IL193097A true IL193097A (en) 2013-03-24

Family

ID=38001788

Family Applications (1)

Application Number Title Priority Date Filing Date
IL193097A IL193097A (en) 2006-01-31 2008-07-28 Methods and kits for early diagnosis of cancer or predisposition to cancer

Country Status (12)

Country Link
US (1) US9394569B2 (enExample)
EP (1) EP1994410B1 (enExample)
JP (1) JP5091163B2 (enExample)
AT (1) ATE486285T1 (enExample)
DE (1) DE602007010108D1 (enExample)
DK (1) DK1994410T3 (enExample)
ES (1) ES2355388T3 (enExample)
IL (1) IL193097A (enExample)
PL (1) PL1994410T3 (enExample)
PT (1) PT1994410E (enExample)
SI (1) SI1994410T1 (enExample)
WO (1) WO2007088537A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2355388T3 (es) 2006-01-31 2011-03-25 Medical Research Fund Of Tel Aviv Sourasky Medical Center Métodos para la detección precoz de cáncer.
EP2220505B1 (en) * 2007-12-10 2015-10-28 The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center Methods of diagnosing cancer
US7888035B2 (en) * 2008-10-30 2011-02-15 Caris Mpi, Inc. Methods for assessing RNA patterns
EP3181705A1 (en) * 2008-11-12 2017-06-21 Caris Life Sciences Switzerland Holdings GmbH Methods and systems of using exosomes for determining phenotypes
US20140148348A1 (en) 2010-01-13 2014-05-29 Christine Kuslich Dectection of gastrointestinal disorders
CN103237901B (zh) 2010-03-01 2016-08-03 卡里斯生命科学瑞士控股有限责任公司 用于治疗诊断的生物标志物
CA2795776A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers for disease
CA2799757C (en) 2010-05-21 2018-12-04 The Governors Of The University Of Alberta Methods for the assessment of colorectal cancer and colorectal polyps by measurement of metabolites in urine
CN105849276B (zh) 2013-10-01 2020-07-24 生命技术公司 用于检测结构变异体的系统和方法
ES2939298T3 (es) 2017-05-21 2023-04-20 Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct Combinación de marcadores para el diagnóstico del cáncer
EP3447154A1 (en) * 2017-08-23 2019-02-27 Instytut Genetyki Sadowej Jolanta Powierska - Czarny Method for detection of mutations, polymorphisms and specific dna sequences on dna matrices with dna imaging techniques for the use in medical diagnostics and forensic genetics
WO2019167047A1 (en) * 2018-02-28 2019-09-06 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods of diagnosing and treating bladder cancer
IL311084A (en) 2018-11-30 2024-04-01 Caris Mpi Inc New generation molecular characterization
CN110777213A (zh) * 2019-11-05 2020-02-11 武汉科技大学 一种潜伏期胃癌诊断试剂盒
WO2021112918A1 (en) 2019-12-02 2021-06-10 Caris Mpi, Inc. Pan-cancer platinum response predictor
US11840720B2 (en) 2019-12-23 2023-12-12 Metabolomic Technologies Inc. Urinary metabolomic biomarkers for detecting colorectal cancer and polyps

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07500411A (ja) * 1991-02-05 1995-01-12 ファロク セィディ 癌胎児性抗原を検出するための簡易検査法
US5741650A (en) * 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples
US7081516B2 (en) * 2002-08-26 2006-07-25 Case Western Reserve University Methods for categorizing patients
AU2003220387A1 (en) * 2002-03-19 2003-10-08 Tularik Inc. Gene amplification in cancer
US20040097448A1 (en) * 2002-11-19 2004-05-20 Isis Pharmaceuticals Inc. Modulation of CD24 expression
WO2005024603A2 (en) * 2003-09-10 2005-03-17 The Board Of Regents Of The University Of Texas System Methods for detecting, diagnosing and treating human renal cell carcinoma
AU2004294547A1 (en) * 2003-11-26 2005-06-16 The Ohio State University Research Foundation Polymorphic CD24 genotypes that are predictive of multiple sclerosis risk and progression
CA2453198A1 (en) 2004-01-07 2005-07-07 Wei-Ping Min Quantification and generation of immune suppressive exosomes
US7666583B2 (en) * 2004-02-19 2010-02-23 Yale University Identification of cancer protein biomarkers using proteomic techniques
ES2355388T3 (es) 2006-01-31 2011-03-25 Medical Research Fund Of Tel Aviv Sourasky Medical Center Métodos para la detección precoz de cáncer.

Also Published As

Publication number Publication date
ATE486285T1 (de) 2010-11-15
US9394569B2 (en) 2016-07-19
WO2007088537A3 (en) 2007-10-25
ES2355388T3 (es) 2011-03-25
SI1994410T1 (sl) 2011-03-31
DE602007010108D1 (enExample) 2010-12-09
EP1994410B1 (en) 2010-10-27
PL1994410T3 (pl) 2011-12-30
JP5091163B2 (ja) 2012-12-05
PT1994410E (pt) 2011-01-10
IL193097A0 (en) 2009-02-11
WO2007088537A2 (en) 2007-08-09
DK1994410T3 (da) 2011-01-31
JP2009525041A (ja) 2009-07-09
EP1994410A2 (en) 2008-11-26
US20100062450A1 (en) 2010-03-11

Similar Documents

Publication Publication Date Title
US9394569B2 (en) Methods and kits for early detection of cancer or predisposition thereto
EP3262190B1 (en) Biomarker panel for the detection of cancer
US11060152B2 (en) Methods for the surveillance, diagnosis and screening of bladder cancer
DK2456889T3 (en) Markers of endometrial cancer
Gupta et al. Expanding the spectrum of IDH1 mutations in gliomas
US11041212B2 (en) ABCA1 downregulation in prostate cancer
Sin et al. Down‐regulation of TROP‐2 predicts poor prognosis of hepatocellular carcinoma patients
US20110151443A1 (en) Marker for gastric cancer
Boissière-Michot et al. Immunohistochemical staining for p16 and BRAFV600E is useful to distinguish between sporadic and hereditary (Lynch syndrome-related) microsatellite instable colorectal carcinomas
JP7721449B2 (ja) Fgfrの決定に基づいて試料を分類する方法
KR20110106244A (ko) 간세포암종의 예후 진단용 단일 염기 다형성
Tran et al. Evaluation of the expression levels of BRAF V600E mRNA in primary tumors of thyroid cancer using an ultrasensitive mutation assay
EP3714070B1 (en) A novel cip2a variant and uses thereof
KR101601943B1 (ko) 난소암 환자의 항암제 치료 반응성 예측을 위한 마커 uchl1
AU2007243181A1 (en) Composition and methods for the detection of Cripto-3
KR101583673B1 (ko) 난소암 환자의 항암제 치료 반응성 예측을 위한 마커 dlx5
KR101601941B1 (ko) 난소암 환자의 항암제 치료 반응성 예측을 위한 마커 mta3
KR101601942B1 (ko) 난소암 환자의 항암제 치료 반응성 예측을 위한 마커 tet1

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees