IL188394A - Quinoline derivatives as antibacterial agents - Google Patents

Quinoline derivatives as antibacterial agents

Info

Publication number
IL188394A
IL188394A IL188394A IL18839407A IL188394A IL 188394 A IL188394 A IL 188394A IL 188394 A IL188394 A IL 188394A IL 18839407 A IL18839407 A IL 18839407A IL 188394 A IL188394 A IL 188394A
Authority
IL
Israel
Prior art keywords
compound
use according
alkyl
hydrogen
halo
Prior art date
Application number
IL188394A
Other languages
English (en)
Other versions
IL188394A0 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL188394A0 publication Critical patent/IL188394A0/en
Publication of IL188394A publication Critical patent/IL188394A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL188394A 2005-06-28 2007-12-25 Quinoline derivatives as antibacterial agents IL188394A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105769 2005-06-28
PCT/EP2006/063556 WO2007000436A1 (en) 2005-06-28 2006-06-26 Quinoline derivatives as antibacterial agents

Publications (2)

Publication Number Publication Date
IL188394A0 IL188394A0 (en) 2008-08-07
IL188394A true IL188394A (en) 2012-09-24

Family

ID=35445742

Family Applications (1)

Application Number Title Priority Date Filing Date
IL188394A IL188394A (en) 2005-06-28 2007-12-25 Quinoline derivatives as antibacterial agents

Country Status (33)

Country Link
US (2) US20100204270A1 (enExample)
EP (1) EP1898910B1 (enExample)
JP (1) JP5193859B2 (enExample)
KR (1) KR101423229B1 (enExample)
CN (1) CN101252928B (enExample)
AP (1) AP2733A (enExample)
AR (1) AR057654A1 (enExample)
AU (1) AU2006263884B2 (enExample)
BR (1) BRPI0612534B8 (enExample)
CA (1) CA2612623C (enExample)
CY (1) CY1118515T1 (enExample)
DK (1) DK1898910T3 (enExample)
EA (1) EA014163B1 (enExample)
ES (1) ES2606772T3 (enExample)
HR (1) HRP20161704T1 (enExample)
HU (1) HUE031268T2 (enExample)
IL (1) IL188394A (enExample)
JO (1) JO3270B1 (enExample)
LT (1) LT1898910T (enExample)
ME (1) ME02690B (enExample)
MX (1) MX2008000082A (enExample)
MY (1) MY151030A (enExample)
NO (1) NO341283B1 (enExample)
NZ (1) NZ564339A (enExample)
PL (1) PL1898910T3 (enExample)
PT (1) PT1898910T (enExample)
RS (1) RS55408B1 (enExample)
SG (1) SG166799A1 (enExample)
SI (1) SI1898910T1 (enExample)
TW (1) TWI392494B (enExample)
UA (1) UA91549C2 (enExample)
WO (1) WO2007000436A1 (enExample)
ZA (1) ZA200711149B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9790186B2 (en) 2009-07-21 2017-10-17 Trustees Of Dartmouth College Composition and method for prevention, mitigation or treatment of an enteropathogenic bacterial infection
AU2013254670B2 (en) 2012-04-27 2017-03-30 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
ES2576491T3 (es) 2012-04-27 2016-07-07 Janssen Pharmaceutica, N.V. Derivados de quinolina antibacterianos
CN105037497B (zh) * 2015-03-27 2018-06-26 中牧实业股份有限公司 一种恩拉霉素的提纯方法
WO2017035288A1 (en) * 2015-08-27 2017-03-02 Trustees Of Dartmouth College Composition and method for prevention, mitigation or treatment of an enteropathogenic bacterial infection

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
SI1527050T1 (sl) * 2002-07-25 2010-08-31 Janssen Pharmaceutica Nv Kinolinski derivati in njihova uporaba kot mikobakterijski inhibitorji
MXPA06013888A (es) * 2004-05-28 2007-01-26 Janssen Pharmaceutica Nv Uso de derivados de quinolina sustituidos para el tratamiento de enfermedades micobacterianas resistentes a los farmacos.
EE05394B1 (et) * 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis

Also Published As

Publication number Publication date
ES2606772T3 (es) 2017-03-27
PT1898910T (pt) 2016-11-16
NO20080481L (no) 2008-02-29
UA91549C2 (ru) 2010-08-10
JO3270B1 (ar) 2018-09-16
RS55408B1 (sr) 2017-04-28
HK1120734A1 (en) 2009-04-09
US20100204270A1 (en) 2010-08-12
AR057654A1 (es) 2007-12-12
EA200800152A1 (ru) 2008-06-30
DK1898910T3 (en) 2017-01-09
NO341283B1 (no) 2017-10-02
CA2612623A1 (en) 2007-01-04
AU2006263884B2 (en) 2013-01-10
HRP20161704T1 (hr) 2017-02-10
WO2007000436A1 (en) 2007-01-04
BRPI0612534A8 (pt) 2017-12-26
CN101252928B (zh) 2012-05-23
MX2008000082A (es) 2008-03-24
SG166799A1 (en) 2010-12-29
EA014163B1 (ru) 2010-10-29
BRPI0612534A2 (pt) 2010-11-23
BRPI0612534B8 (pt) 2021-05-25
US20130030017A1 (en) 2013-01-31
EP1898910B1 (en) 2016-09-28
CY1118515T1 (el) 2017-07-12
ZA200711149B (en) 2009-06-24
CA2612623C (en) 2016-09-27
HUE031268T2 (en) 2017-06-28
LT1898910T (lt) 2017-01-10
TW200738237A (en) 2007-10-16
AU2006263884A1 (en) 2007-01-04
MY151030A (en) 2014-03-31
BRPI0612534B1 (pt) 2020-04-22
JP2008546825A (ja) 2008-12-25
TWI392494B (zh) 2013-04-11
JP5193859B2 (ja) 2013-05-08
SI1898910T1 (sl) 2017-01-31
KR20080028460A (ko) 2008-03-31
PL1898910T3 (pl) 2017-03-31
CN101252928A (zh) 2008-08-27
EP1898910A1 (en) 2008-03-19
IL188394A0 (en) 2008-08-07
NZ564339A (en) 2011-02-25
AP2733A (en) 2013-09-30
ME02690B (me) 2017-10-20
KR101423229B1 (ko) 2014-07-25

Similar Documents

Publication Publication Date Title
EP1901743B1 (en) Quinoline derivatives as antibacterial agents
EP1912648B1 (en) Quinoline derivatives as antibacterial agents
US20130030016A1 (en) Quinoline derivatives as antibacterial agents
US20130030017A1 (en) Quinoline derivatives as antibacterial agents
EP1912649B1 (en) Quinoline derivatives as antibacterial agents
EP1898914B1 (en) Quinoline derivatives as antibacterial agents
US20100197727A1 (en) Quinoline Derivatives as Antibacterial Agents

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed