IL182978A0 - Macrolones-amino substituted quinolones - Google Patents

Macrolones-amino substituted quinolones

Info

Publication number
IL182978A0
IL182978A0 IL182978A IL18297807A IL182978A0 IL 182978 A0 IL182978 A0 IL 182978A0 IL 182978 A IL182978 A IL 182978A IL 18297807 A IL18297807 A IL 18297807A IL 182978 A0 IL182978 A0 IL 182978A0
Authority
IL
Israel
Prior art keywords
macrolones
amino substituted
substituted quinolones
quinolones
amino
Prior art date
Application number
IL182978A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Glaxosmithkline Istraziv Acki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Glaxosmithkline Istraziv Acki filed Critical Glaxo Group Ltd
Publication of IL182978A0 publication Critical patent/IL182978A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL182978A 2004-11-11 2007-05-03 Macrolones-amino substituted quinolones IL182978A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0424959A GB0424959D0 (en) 2004-11-11 2004-11-11 Novel compounds
PCT/EP2005/012038 WO2006050942A1 (en) 2004-11-11 2005-11-09 Macrolones - amino substituted quinolones

Publications (1)

Publication Number Publication Date
IL182978A0 true IL182978A0 (en) 2007-08-19

Family

ID=33523587

Family Applications (1)

Application Number Title Priority Date Filing Date
IL182978A IL182978A0 (en) 2004-11-11 2007-05-03 Macrolones-amino substituted quinolones

Country Status (19)

Country Link
US (2) US7718621B2 (enExample)
EP (1) EP1824870A1 (enExample)
JP (1) JP2008519788A (enExample)
KR (1) KR20070085919A (enExample)
CN (1) CN101098881A (enExample)
AR (1) AR053311A1 (enExample)
AU (1) AU2005303961A1 (enExample)
BR (1) BRPI0517792A (enExample)
CA (1) CA2587413A1 (enExample)
GB (1) GB0424959D0 (enExample)
IL (1) IL182978A0 (enExample)
MA (1) MA29213B1 (enExample)
MX (1) MX2007005776A (enExample)
NO (1) NO20072939L (enExample)
PE (1) PE20061137A1 (enExample)
RU (1) RU2007121581A (enExample)
TW (1) TW200630378A (enExample)
WO (1) WO2006050942A1 (enExample)
ZA (1) ZA200703603B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
WO2007054295A1 (en) * 2005-11-09 2007-05-18 Glaxo Group Limited New 4*-substituted erythromycin derivative
EP1879904A1 (en) * 2005-05-10 2008-01-23 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. 4" amino linked macrolides useful for the treatment of microbial infections
WO2007054296A1 (en) * 2005-11-09 2007-05-18 Glaxo Group Limited Macrolones
NZ583878A (en) 2007-09-14 2012-10-26 Vertex Pharma Modulators of ABC transporter and cystic fibrosis transmembrane conductance regulator (CFTR)
AU2008316830B2 (en) 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides
CN107854477A (zh) 2008-10-24 2018-03-30 森普拉制药公司 使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
BR112012029586A2 (pt) * 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20130120458A (ko) 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en) 2013-03-15 2018-08-09 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CN106589023A (zh) * 2016-11-22 2017-04-26 宜昌东阳光药业股份有限公司 一种罗红霉素杂质及其合成方法
CN110475777B (zh) 2017-03-30 2022-04-15 豪夫迈·罗氏有限公司 用于治疗和预防细菌感染的新吡啶并[2,3-b]吲哚化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds

Also Published As

Publication number Publication date
US20080090773A1 (en) 2008-04-17
MX2007005776A (es) 2007-07-16
PE20061137A1 (es) 2006-12-13
AR053311A1 (es) 2007-05-02
TW200630378A (en) 2006-09-01
EP1824870A1 (en) 2007-08-29
US20080269146A1 (en) 2008-10-30
NO20072939L (no) 2007-08-08
MA29213B1 (fr) 2008-02-01
KR20070085919A (ko) 2007-08-27
RU2007121581A (ru) 2008-12-20
US7718621B2 (en) 2010-05-18
CN101098881A (zh) 2008-01-02
GB0424959D0 (en) 2004-12-15
AU2005303961A1 (en) 2006-05-18
JP2008519788A (ja) 2008-06-12
CA2587413A1 (en) 2006-05-18
WO2006050942A1 (en) 2006-05-18
ZA200703603B (en) 2008-07-30
BRPI0517792A (pt) 2008-10-21

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