IL179099A - Monoclonal antibody and il-21 polypeptide for use in treating cancer - Google Patents
Monoclonal antibody and il-21 polypeptide for use in treating cancerInfo
- Publication number
- IL179099A IL179099A IL179099A IL17909906A IL179099A IL 179099 A IL179099 A IL 179099A IL 179099 A IL179099 A IL 179099A IL 17909906 A IL17909906 A IL 17909906A IL 179099 A IL179099 A IL 179099A
- Authority
- IL
- Israel
- Prior art keywords
- cells
- polypeptide
- monoclonal antibody
- rituximab
- cell
- Prior art date
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Landscapes
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| US68044705P | 2005-05-12 | 2005-05-12 | |
| PCT/US2005/019126 WO2005113001A1 (en) | 2004-05-20 | 2005-05-20 | Methods of treating cancer using il-21 and monoclonal antibody therapy |
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| IL179099A0 IL179099A0 (en) | 2007-03-08 |
| IL179099A true IL179099A (en) | 2011-03-31 |
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| ES2390278T3 (es) * | 2004-05-20 | 2012-11-08 | Zymogenetics, Inc. | Procedimientos de tratamiento del cáncer usando tratamiento con IL-21 y anticuerpos monoclonales |
| US20070218116A1 (en) * | 2006-03-14 | 2007-09-20 | Schwendener Reto A | Compositions and methods for the treatment of tumors and tumor metastases |
| AU2007310777A1 (en) | 2006-10-26 | 2008-05-02 | Novo Nordisk A/S | IL-21 variants |
| KR100902340B1 (ko) * | 2007-08-02 | 2009-06-12 | 한국생명공학연구원 | Ｙｃ－１ 또는 ｉｌ－２１을 유효성분으로 포함하는자연살해세포 분화제 및 분화 방법 |
| US8506933B2 (en) * | 2007-11-30 | 2013-08-13 | Msdx, Inc. | Methods of detecting a neurological condition via analysis of circulating phagocytes |
| WO2011019670A1 (en) * | 2009-08-10 | 2011-02-17 | Nayak Ramesh C | Methods of detecting responses to therapies using perforin levels |
| EP2504699A1 (en) * | 2009-11-27 | 2012-10-03 | MSDX, Inc. | Methods of detecting or monitoring activity of an inflammatory or neurodegenerative condition |
| US8673309B2 (en) | 2011-02-11 | 2014-03-18 | Msdx, Inc. | Methods for measuring high molecular weight complexes of fibrinogen with fibronectin and fibulin-1 |
| US9447160B2 (en) * | 2012-01-19 | 2016-09-20 | University Of Miami | Compositions, methods and kits for treatment of cancer and autoimmune diseases |
| WO2013169693A1 (en) | 2012-05-09 | 2013-11-14 | Bristol-Myers Squibb Company | Methods of treating cancer using an il-21 polypeptide and an anti-pd-1 antibody |
| KR101453462B1 (ko) | 2013-05-16 | 2014-10-23 | 앱클론(주) | Her2에 특이적으로 결합하는 항체 |
| CA3208721A1 (en) | 2014-04-08 | 2015-10-15 | Boston Pharmaceuticals Inc. | Binding molecules specific for il-21 and uses thereof |
| KR20160120157A (ko) | 2015-04-07 | 2016-10-17 | 주식회사 메드팩토 | 암 예방 또는 치료용 약학적 조성물 및 이를 이용한 방법 |
| US20200016200A1 (en) * | 2016-10-03 | 2020-01-16 | Baylor College Of Medicine | Modulating cytotoxic cell lytic granule positioning to promote diffuse killing in cellular therapies |
| CA3075900A1 (en) * | 2017-09-15 | 2019-03-21 | Beckman Coulter, Inc. | Flow based assays for therapeutics |
| KR102265437B1 (ko) * | 2017-11-24 | 2021-06-15 | 의료법인 성광의료재단 | Nk 배양용 조성물 및 이를 이용하여 nk 세포를 배양하는 방법 |
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| EP0721983A1 (en) | 1988-01-22 | 1996-07-17 | ZymoGenetics, Inc. | Methods of producing biologically active peptide dimers |
| US5736137A (en) | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| US6057128A (en) * | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
| MY136203A (en) | 1998-08-11 | 2008-08-29 | Idec Pharma Corp | Combination therapies for b-cell lymphomas comprising administration of anti-cd20 antibody |
| US6307024B1 (en) * | 1999-03-09 | 2001-10-23 | Zymogenetics, Inc. | Cytokine zalpha11 Ligand |
| WO2001001748A2 (en) * | 1999-07-02 | 2001-01-11 | Genentech, Inc. | Peptide compounds that bind her2 |
| IT1311703B1 (it) | 1999-07-23 | 2002-03-19 | Sipa Spa | Impianto ad alta efficienza di soffiaggio di preforme |
| WO2001077171A2 (en) | 2000-04-05 | 2001-10-18 | Zymogenetics, Inc. | Soluble zalpha11 cytokine receptors |
| US7306801B2 (en) * | 2000-05-15 | 2007-12-11 | Health Research, Inc. | Methods of therapy for cancers characterized by overexpression of the HER2 receptor protein |
| AU2002362098A1 (en) | 2001-12-07 | 2003-06-23 | Chiron Corporation | Methods of therapy for non-hodgkin's lymphoma |
| CN100522999C (zh) * | 2002-02-14 | 2009-08-05 | 免疫医疗公司 | 抗cd20抗体及其融合蛋白和使用方法 |
| US7452535B2 (en) * | 2002-04-12 | 2008-11-18 | Medarex, Inc. | Methods of treatment using CTLA-4 antibodies |
| US20040016010A1 (en) * | 2002-04-17 | 2004-01-22 | Marion Kasaian | IL-21 receptor knockout animal and methods of use thereof |
| ES2381265T3 (es) * | 2002-06-07 | 2012-05-24 | Zymogenetics, Inc. | Uso de IL-21 y anticuerpo monoclonal para tratar cánceres sólidos |
| KR20050065587A (ko) * | 2002-10-08 | 2005-06-29 | 이뮤노메딕스, 인코오포레이티드 | 항체 치료법 |
| US20070092485A1 (en) * | 2002-11-15 | 2007-04-26 | Zymogenetics, Inc. | Cytokine zalpha11 ligand |
| PL209009B1 (pl) * | 2002-12-13 | 2011-07-29 | Zymogenetics Inc | Wektor ekspresyjny do otrzymywania białka IL-21, komórka prokariotycznego gospodarza i sposób otrzymywania białek |
| US7465446B2 (en) | 2003-05-30 | 2008-12-16 | Medarex, Inc. | Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease |
| MXPA06004199A (es) * | 2003-10-17 | 2006-06-28 | Novo Nordisk As | Terapia en combinacion. |
| ES2390278T3 (es) * | 2004-05-20 | 2012-11-08 | Zymogenetics, Inc. | Procedimientos de tratamiento del cáncer usando tratamiento con IL-21 y anticuerpos monoclonales |
| LT1814580T (lt) * | 2004-11-24 | 2016-12-12 | Fred Hutchinson Cancer Research Center | Il 21 naudojimo pritaikomajai imunoterapijai ir naviko antigenų identifikavimo metodai |
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