IL169127A0 - Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin d derivative - Google Patents
Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin d derivativeInfo
- Publication number
- IL169127A0 IL169127A0 IL169127A IL16912705A IL169127A0 IL 169127 A0 IL169127 A0 IL 169127A0 IL 169127 A IL169127 A IL 169127A IL 16912705 A IL16912705 A IL 16912705A IL 169127 A0 IL169127 A0 IL 169127A0
- Authority
- IL
- Israel
- Prior art keywords
- alendronate
- phosphonate
- vitamin
- bis
- derivative
- Prior art date
Links
- OGSPWJRAVKPPFI-UHFFFAOYSA-N Alendronic Acid Chemical compound NCCCC(O)(P(O)(O)=O)P(O)(O)=O OGSPWJRAVKPPFI-UHFFFAOYSA-N 0.000 title 1
- 229940122361 Bisphosphonate Drugs 0.000 title 1
- 229940062527 alendronate Drugs 0.000 title 1
- 150000004663 bisphosphonates Chemical class 0.000 title 1
- 150000003710 vitamin D derivatives Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43368502P | 2002-12-16 | 2002-12-16 | |
US46020603P | 2003-04-02 | 2003-04-02 | |
PCT/US2003/040174 WO2004058235A2 (fr) | 2002-12-16 | 2003-12-16 | Methode pouvant augmenter la biodisponibilite d'alendronate ou autre diphosphonate par administration d'une predose d'un derive de la vitamine d |
Publications (1)
Publication Number | Publication Date |
---|---|
IL169127A0 true IL169127A0 (en) | 2009-02-11 |
Family
ID=32685268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL169127A IL169127A0 (en) | 2002-12-16 | 2005-06-09 | Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin d derivative |
Country Status (7)
Country | Link |
---|---|
JP (3) | JP2006514695A (fr) |
AU (1) | AU2003300984A1 (fr) |
DE (1) | DE10393906T5 (fr) |
GB (1) | GB2411116B (fr) |
HK (1) | HK1078802A1 (fr) |
IL (1) | IL169127A0 (fr) |
WO (1) | WO2004058235A2 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1993559T3 (en) * | 2006-02-03 | 2016-10-03 | Opko Renal Llc | Treatment of vitamin D deficiency and MALFUNCTION with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 |
WO2007094779A1 (fr) * | 2006-02-14 | 2007-08-23 | Teva Pharmaceutical Industries Ltd. | Formules pharmaceutiques de polymères d'amines aliphatiques et méthodes de fabrication desdites formules |
ES2670029T3 (es) | 2006-06-21 | 2018-05-29 | Opko Ireland Global Holdings, Ltd. | Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D |
WO2008074145A1 (fr) * | 2006-12-20 | 2008-06-26 | Genpharm Ulc | Composition pharmaceutique comprenant un lubrifiant granulé thermofusible |
US20100179110A1 (en) * | 2006-12-20 | 2010-07-15 | Mostafa Akbarieh | Composition Containing a Bisphosphonic Acid in Combination with Vitamin D |
CA2684778C (fr) | 2007-04-25 | 2017-09-05 | Cytochroma Inc. | Procedes et composes pour une therapie a base de vitamine d |
EP3225243A1 (fr) | 2007-04-25 | 2017-10-04 | Opko Renal, LLC | Procédé sûr et efficace de traitement et de prévention de l'hyperparathyroïdisme secondaire dans une maladie rénale chronique |
KR101495578B1 (ko) | 2007-04-25 | 2015-02-25 | 사이토크로마 인코포레이티드 | 비타민 d 부족 및 결핍의 치료 방법 |
DK2481400T3 (da) | 2007-04-25 | 2014-09-29 | Opko Ip Holdings Ii Inc | Orale præparater med kontrolleret frigivelse omfattende en vitamin D-forbindelse og en voksagtig bærer |
ES2954932T3 (es) | 2008-04-02 | 2023-11-27 | Eirgen Pharma Ltd | Métodos, composiciones, usos y kits útiles para la deficiencia de vitamina D y trastornos relacionados |
CN105796530A (zh) | 2010-03-29 | 2016-07-27 | 赛特克罗公司 | 用于降低甲状旁腺水平的方法和组合物 |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
IL290855B2 (en) | 2016-03-28 | 2024-06-01 | Eirgen Pharma Ltd | Treatment methods using vitamin D |
CN109364034B (zh) * | 2018-11-26 | 2021-05-04 | 正大制药(青岛)有限公司 | 一种骨化三醇制剂及其制备方法 |
CN116211818B (zh) * | 2023-03-10 | 2024-04-09 | 菲洋生物科技(吉林)有限公司 | 一种含有阿仑膦酸钠的片剂及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100317935B1 (ko) * | 1999-10-20 | 2001-12-22 | 유승필 | 대사성 골질환 치료용 약제조성물 및 이의 제조방법 |
CA2454200A1 (fr) * | 2001-07-17 | 2003-01-30 | Teva Pharmaceutical Industries Ltd. | Formes posologiques pour la liberation gastrique immediate d'un stimulateur de transport du calcium et la liberation gastrique retardee d'un bis-phosphonate |
-
2003
- 2003-12-16 DE DE10393906T patent/DE10393906T5/de not_active Withdrawn
- 2003-12-16 WO PCT/US2003/040174 patent/WO2004058235A2/fr active Application Filing
- 2003-12-16 GB GB0511750A patent/GB2411116B/en not_active Expired - Fee Related
- 2003-12-16 AU AU2003300984A patent/AU2003300984A1/en not_active Abandoned
- 2003-12-16 JP JP2005509984A patent/JP2006514695A/ja not_active Withdrawn
-
2005
- 2005-06-09 IL IL169127A patent/IL169127A0/en not_active IP Right Cessation
-
2006
- 2006-02-06 HK HK06101577.3A patent/HK1078802A1/xx not_active IP Right Cessation
-
2011
- 2011-08-02 JP JP2011169179A patent/JP2011241221A/ja not_active Withdrawn
-
2014
- 2014-07-25 JP JP2014152061A patent/JP2014205711A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
GB2411116B (en) | 2009-04-29 |
JP2006514695A (ja) | 2006-05-11 |
JP2014205711A (ja) | 2014-10-30 |
AU2003300984A8 (en) | 2004-07-22 |
JP2011241221A (ja) | 2011-12-01 |
WO2004058235A3 (fr) | 2005-02-24 |
GB0511750D0 (en) | 2005-07-20 |
AU2003300984A1 (en) | 2004-07-22 |
GB2411116A (en) | 2005-08-24 |
HK1078802A1 (en) | 2006-03-24 |
DE10393906T5 (de) | 2006-01-12 |
WO2004058235A2 (fr) | 2004-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |