IL166337A - Oral administration of calcitonin - Google Patents

Oral administration of calcitonin

Info

Publication number
IL166337A
IL166337A IL166337A IL16633705A IL166337A IL 166337 A IL166337 A IL 166337A IL 166337 A IL166337 A IL 166337A IL 16633705 A IL16633705 A IL 16633705A IL 166337 A IL166337 A IL 166337A
Authority
IL
Israel
Prior art keywords
calcitonin
minutes
cnac
acid
oral delivery
Prior art date
Application number
IL166337A
Other languages
English (en)
Other versions
IL166337A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL166337A0 publication Critical patent/IL166337A0/xx
Publication of IL166337A publication Critical patent/IL166337A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/22—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of calcitonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL166337A 2002-08-01 2005-01-17 Oral administration of calcitonin IL166337A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40013902P 2002-08-01 2002-08-01
PCT/EP2003/008498 WO2004012772A1 (en) 2002-08-01 2003-07-31 Oral administration of calcitonin

Publications (2)

Publication Number Publication Date
IL166337A0 IL166337A0 (en) 2006-01-16
IL166337A true IL166337A (en) 2011-10-31

Family

ID=31495795

Family Applications (1)

Application Number Title Priority Date Filing Date
IL166337A IL166337A (en) 2002-08-01 2005-01-17 Oral administration of calcitonin

Country Status (19)

Country Link
US (2) US20060135402A1 (enExample)
EP (1) EP1526871A1 (enExample)
JP (4) JP2005535689A (enExample)
KR (6) KR20130004389A (enExample)
CN (1) CN1671418A (enExample)
AR (1) AR040737A1 (enExample)
AU (1) AU2003260346B2 (enExample)
BR (1) BR0313177A (enExample)
CA (1) CA2494212A1 (enExample)
IL (1) IL166337A (enExample)
MX (1) MXPA05001266A (enExample)
NO (1) NO20051023L (enExample)
NZ (1) NZ537944A (enExample)
PE (1) PE20040724A1 (enExample)
PL (1) PL373143A1 (enExample)
RU (1) RU2355417C2 (enExample)
TW (1) TWI307279B (enExample)
WO (1) WO2004012772A1 (enExample)
ZA (1) ZA200500516B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007035718A2 (en) 2005-09-19 2007-03-29 Emisphere Technologies, Inc. Crystalline forms of the di-sodium salt of n-(5-chlorosalicyloyl)-8-aminocaprylic acid
GB0522566D0 (en) * 2005-11-04 2005-12-14 Novartis Ag Organic compounds
CN107050433A (zh) * 2007-03-02 2017-08-18 诺华股份有限公司 降钙素的口服施用
WO2009019307A2 (en) * 2007-08-09 2009-02-12 Novartis Ag Oral calcitonin compositions and applications thereof
KR101344369B1 (ko) 2007-11-02 2013-12-24 에미스페어 테크놀로지스, 인코포레이티드 비타민 ｂ12 결핍 치료방법
JP5985985B2 (ja) * 2009-08-03 2016-09-06 エミスフィアー テクノロジーズ インコーポレイテッドＥｍｉｓｐｈｅｒｅ Ｔｅｃｈｎｏｌｏｇｉｅｓ，Ｉｎｃ． 胃腸への影響が減少した即効型ナプロキセン組成物
WO2012130193A1 (en) 2011-03-31 2012-10-04 Zentiva, K.S. Non-covalent soluble complexes of teriparatide with polysaccharides and a dosage form of teriparatide for oral administration
CN104095828A (zh) * 2014-07-29 2014-10-15 中国药科大学 一种降钙素口服肠溶组合物及其制备方法
US10583177B2 (en) * 2015-02-09 2020-03-10 Entera Bio Ltd. Formulations for oral administration of active agents
CN104961687B (zh) * 2015-06-03 2017-07-25 苏州维泰生物技术有限公司 1,2‑二嗪衍生物及其制剂、用途
CN116850132A (zh) 2016-08-17 2023-10-10 安提拉生物有限公司 用于口服的活性剂的制剂
CR20230308A (es) 2020-12-11 2023-09-08 Civi Biopharma Inc Entrega oral de conjugados antisentido que tienen por blanco a pcsk9
CA3216091A1 (en) 2021-04-22 2022-10-27 Henrik Oerum Oral delivery of oligonucleotides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629020A (en) * 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
AU4218400A (en) * 1999-04-05 2000-10-23 Emisphere Technologies, Inc. Lyophilized solid dosage forms and methods of making
IL145546A0 (en) * 1999-04-05 2002-06-30 Emisphere Tech Inc Disodium salts, monohydrates, and ethanol solvates for delivering active agents
US7049283B2 (en) * 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents

Also Published As

Publication number Publication date
JP2005535689A (ja) 2005-11-24
WO2004012772A1 (en) 2004-02-12
IL166337A0 (en) 2006-01-16
JP2014062112A (ja) 2014-04-10
AU2003260346A1 (en) 2004-02-23
CA2494212A1 (en) 2004-02-12
AR040737A1 (es) 2005-04-20
KR20050032101A (ko) 2005-04-06
TW200408409A (en) 2004-06-01
RU2355417C2 (ru) 2009-05-20
TWI307279B (en) 2009-03-11
KR20170097232A (ko) 2017-08-25
JP2016056190A (ja) 2016-04-21
US20070232524A1 (en) 2007-10-04
RU2005105691A (ru) 2006-01-20
PL373143A1 (en) 2005-08-22
NZ537944A (en) 2006-11-30
KR20160113319A (ko) 2016-09-28
US7569539B2 (en) 2009-08-04
PE20040724A1 (es) 2004-12-06
KR20130004389A (ko) 2013-01-09
JP2011026348A (ja) 2011-02-10
US20060135402A1 (en) 2006-06-22
CN1671418A (zh) 2005-09-21
ZA200500516B (en) 2006-07-26
EP1526871A1 (en) 2005-05-04
KR20140084354A (ko) 2014-07-04
NO20051023L (no) 2005-04-27
JP5941035B2 (ja) 2016-06-29
KR20110014690A (ko) 2011-02-11
MXPA05001266A (es) 2005-04-28
AU2003260346B2 (en) 2007-12-13
BR0313177A (pt) 2005-06-14

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KR100847695B1 (ko) 약리학적 활성 약물의 경구적 전달을 위한 약제학적 조성물
US6352974B1 (en) Oral calcitonin pharmaceutical compositions and methods of making the same
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