IL165516A0 - Toluidine blue o drug substance and use thereof for in vivo staining and chemotherapeutic treatment of dysplastic tissues - Google Patents

Toluidine blue o drug substance and use thereof for in vivo staining and chemotherapeutic treatment of dysplastic tissues

Info

Publication number
IL165516A0
IL165516A0 IL16551602A IL16551602A IL165516A0 IL 165516 A0 IL165516 A0 IL 165516A0 IL 16551602 A IL16551602 A IL 16551602A IL 16551602 A IL16551602 A IL 16551602A IL 165516 A0 IL165516 A0 IL 165516A0
Authority
IL
Israel
Prior art keywords
drug substance
toluidine blue
chemotherapeutic treatment
vivo staining
dysplastic tissues
Prior art date
Application number
IL16551602A
Other languages
English (en)
Original Assignee
Zila Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zila Inc filed Critical Zila Inc
Publication of IL165516A0 publication Critical patent/IL165516A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B21/00—Thiazine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL16551602A 2002-06-04 2002-06-04 Toluidine blue o drug substance and use thereof for in vivo staining and chemotherapeutic treatment of dysplastic tissues IL165516A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/017720 WO2003103569A2 (en) 2002-06-04 2002-06-04 Toluidine blue o drug substance and use thereof for in vivo staining and chemotherapeutic treatment of dysplastic tissues

Publications (1)

Publication Number Publication Date
IL165516A0 true IL165516A0 (en) 2006-01-15

Family

ID=29731309

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16551602A IL165516A0 (en) 2002-06-04 2002-06-04 Toluidine blue o drug substance and use thereof for in vivo staining and chemotherapeutic treatment of dysplastic tissues

Country Status (9)

Country Link
EP (1) EP1534346A4 (ja)
JP (1) JP2005535605A (ja)
CN (1) CN1302815C (ja)
AU (1) AU2002312319A1 (ja)
BR (1) BRPI0215775A2 (ja)
IL (1) IL165516A0 (ja)
MX (1) MXPA04012031A (ja)
TW (1) TW200733956A (ja)
WO (1) WO2003103569A2 (ja)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH071257B2 (ja) * 1985-09-09 1995-01-11 エスエス製薬株式会社 混合ビタミン剤中の水溶性ビタミン類の同時定量法
JPS6410171A (en) * 1987-07-03 1989-01-13 Shimadzu Corp Analysis of amino acid
ES2133143T3 (es) * 1991-10-31 1999-09-01 Zila Inc Composicion de tincion biologica, procedimiento de preparacion y procedimiento de utilizacion para la deteccion del cancer epitelial.
US6086852A (en) * 1997-11-13 2000-07-11 Zila, Inc. In vivo stain composition, process of manufacture, and methods of use to identify dysplastic tissue
US6194573B1 (en) * 1997-11-13 2001-02-27 Zila, Inc. Process for manufacture of in vivo stain composition
AU5357498A (en) * 1997-11-13 1999-06-07 Zila, Inc. (in vivo) stain composition, process of manufacture, and methods of use to identify dysplastic tissue
WO2001064110A1 (en) * 2000-02-28 2001-09-07 Zila, Inc. Method for detecting and killing epithelial cancer cells
JP4424838B2 (ja) * 2000-08-31 2010-03-03 株式会社トクヤマ 四級アンモニウム塩の分析方法

Also Published As

Publication number Publication date
AU2002312319A1 (en) 2003-12-22
EP1534346A4 (en) 2007-07-25
MXPA04012031A (es) 2005-03-07
CN1627961A (zh) 2005-06-15
TW200733956A (en) 2007-09-16
WO2003103569A2 (en) 2003-12-18
BRPI0215775A2 (pt) 2016-07-05
CN1302815C (zh) 2007-03-07
WO2003103569A3 (en) 2004-05-21
JP2005535605A (ja) 2005-11-24
EP1534346A2 (en) 2005-06-01

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