IL165378A0 - Nebulizer formulations of dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereof - Google Patents
Nebulizer formulations of dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereofInfo
- Publication number
- IL165378A0 IL165378A0 IL16537803A IL16537803A IL165378A0 IL 165378 A0 IL165378 A0 IL 165378A0 IL 16537803 A IL16537803 A IL 16537803A IL 16537803 A IL16537803 A IL 16537803A IL 165378 A0 IL165378 A0 IL 165378A0
- Authority
- IL
- Israel
- Prior art keywords
- dehydroepiandrosterone
- compositions
- methods
- pulmonary disease
- chronic obstructive
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38924202P | 2002-06-17 | 2002-06-17 | |
US47798703P | 2003-06-11 | 2003-06-11 | |
PCT/US2003/018945 WO2003105775A2 (en) | 2002-06-17 | 2003-06-17 | Dihydrate dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compostions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL165378A0 true IL165378A0 (en) | 2006-01-15 |
Family
ID=29740120
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16537803A IL165378A0 (en) | 2002-06-17 | 2003-06-17 | Nebulizer formulations of dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereof |
IL16529103A IL165291A0 (en) | 2002-06-17 | 2003-06-17 | Dihydrate dehydroepiandorosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16529103A IL165291A0 (en) | 2002-06-17 | 2003-06-17 | Dihydrate dehydroepiandorosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereof |
Country Status (11)
Country | Link |
---|---|
US (1) | US20090087389A1 (de) |
EP (2) | EP1513509A4 (de) |
JP (2) | JP2005537296A (de) |
KR (2) | KR20060011784A (de) |
CN (2) | CN1681520A (de) |
AU (2) | AU2003269889B2 (de) |
BR (2) | BR0311883A (de) |
CA (2) | CA2491846A1 (de) |
IL (2) | IL165378A0 (de) |
MX (2) | MXPA04012720A (de) |
WO (2) | WO2004012653A2 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2298315A1 (de) * | 2002-08-28 | 2011-03-23 | Harbor BioSciences, Inc. | Therapeutische Behandlungsmethoden |
US7601695B2 (en) | 2003-03-10 | 2009-10-13 | Optimer Pharmaceuticals, Inc. | Antibacterial agents |
US7858607B2 (en) * | 2003-03-14 | 2010-12-28 | Mamchur Stephen A | System for use by compounding pharmacists to produce hormone replacement medicine customized for each consumer |
EP1898894A1 (de) * | 2005-06-17 | 2008-03-19 | Boehringer Ingelheim International GmbH | Mrp-iv-hemmer zur behandlung von atemwegserkrankungen |
GB0520794D0 (en) * | 2005-10-12 | 2005-11-23 | Innovata Biomed Ltd | Inhaler |
RU2008142388A (ru) * | 2006-04-03 | 2010-05-10 | Тева Фармасьютикл Индастриес Лтд. (Il) | Микрочастицы лекарственного вещества |
JP5554702B2 (ja) * | 2007-06-05 | 2014-07-23 | パカ パルモナリー ファーマシューティカルズ, インコーポレイテッド | 薬剤を肺に送達するための方法および組成物 |
CN101917850B (zh) | 2007-10-25 | 2016-01-13 | 森普拉制药公司 | 大环内酯类抗菌剂的制备方法 |
ES2565083T3 (es) | 2008-10-24 | 2016-03-31 | Cempra Pharmaceuticals, Inc. | Biodefensas usando macrólidos que contienen triazol |
CA2744940A1 (en) | 2008-12-10 | 2010-06-17 | Paka Pulmonary Pharmaceuticals, Inc. | Methods and compositions for delivery of medicaments to the lungs |
US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
CN108310000A (zh) | 2009-09-10 | 2018-07-24 | 森普拉制药公司 | 治疗疟疾、结核病和mac疾病的方法 |
RU2608390C2 (ru) | 2010-05-20 | 2017-01-18 | Семпра Фармасьютикалз, Инк. | Способы получения макролидов и кетолидов, и промежуточных соединений для их получения |
KR20130120458A (ko) | 2010-09-10 | 2013-11-04 | 셈프라 파마슈티컬스, 인크. | 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드 |
KR20140139083A (ko) | 2012-03-27 | 2014-12-04 | 셈프라 파마슈티컬스, 인크. | 마크롤라이드계 항생제를 투여하기 위한 비경구 제제 |
JP6426696B2 (ja) * | 2013-03-14 | 2018-11-21 | センプラ ファーマシューティカルズ,インコーポレイテッド | 呼吸器疾患の治療のための方法および製剤 |
AU2014233240B2 (en) | 2013-03-15 | 2018-08-09 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
WO2014172706A1 (en) * | 2013-04-19 | 2014-10-23 | University Of Houston System | Cocrystalline dhea formulations |
Family Cites Families (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3943987A (en) * | 1974-10-17 | 1976-03-16 | Rossi Thomas J | Reclosable air-tight containers with evacuation means |
US4379842A (en) * | 1980-02-13 | 1983-04-12 | Hoffmann-La Roche Inc. | Process for the manufacture of 1α-hydroxydehydroepiandrosterone |
US4393066A (en) * | 1981-06-05 | 1983-07-12 | Garrett David M | Method for treatment of herpetic lesions |
US4499064A (en) * | 1982-06-03 | 1985-02-12 | Clayton Foundation For Research | Assessment of nutritional status of individuals |
US4518595A (en) * | 1983-07-19 | 1985-05-21 | The Jackson Laboratory | Method for treating diabetes using DHEA compounds |
US4575498A (en) * | 1983-07-21 | 1986-03-11 | Duke University | Method for restoring depleted purine nucleotide pools |
US4628052A (en) * | 1985-05-28 | 1986-12-09 | Peat Raymond F | Pharmaceutical compositions containing dehydroepiandrosterone and other anesthetic steroids in the treatment of arthritis and other joint disabilities |
JPS63104924A (ja) * | 1986-10-20 | 1988-05-10 | Kanebo Ltd | 膣坐剤 |
NL194728C (nl) * | 1987-04-16 | 2003-01-07 | Hollis Eden Pharmaceuticals | Farmaceutisch preparaat geschikt voor de profylaxe of therapie van een retrovirale infectie of een complicatie of gevolg daarvan. |
CH673459A5 (de) * | 1987-05-15 | 1990-03-15 | Eprova Ag | |
ES2043897T3 (es) * | 1988-01-28 | 1994-01-01 | Koeltringer Peter | Preparado de combinacion, en especial para el tratamiento de enfermedades de las celulas nerviosas. |
FR2631828B1 (fr) * | 1988-05-27 | 1994-05-20 | Spiral Recherche Developpement | Utilisation d'une substance folinique en tant qu'agent antiagregant plaquettaire |
US4931441A (en) * | 1988-11-09 | 1990-06-05 | Luitpold Pharmaceuticals, Inc. | Stabilized aqueous leucovorin calcium compositions |
US4920115A (en) * | 1988-12-28 | 1990-04-24 | Virginia Commonwealth University | Method of lowering LDL cholesterol in blood |
US5407684A (en) * | 1988-12-30 | 1995-04-18 | Virginia Commonwealth University | Use of DHEA as a medicinal |
US5077284A (en) * | 1988-12-30 | 1991-12-31 | Loria Roger M | Use of dehydroepiandrosterone to improve immune response |
IT1229517B (it) * | 1989-01-31 | 1991-09-03 | Bioresearch Spa | Impiego di acido 5-metiltetraidrofolico, di acido 5 formiltetraidrofolico, e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato adatte ad essere impiegate nella terapia dei disordini depressivi e composizioni farmaceutiche relative. |
IT1229203B (it) * | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
NL8901432A (nl) * | 1989-06-06 | 1991-01-02 | Pharmachemie Bv | Bij koelkasttemperatuur stabiele waterige folinaatoplossing, alsmede werkwijze ter bereiding daarvan. |
US4985443A (en) * | 1989-08-04 | 1991-01-15 | Montes Leopoldo F | Method and composition for treating vitiligo |
US5173488A (en) * | 1989-08-21 | 1992-12-22 | American Cyanamid Company | Stable injectable pharmaceutical formulation for folic acid and leucovorin salts and method |
US5270305A (en) * | 1989-09-08 | 1993-12-14 | Glaxo Group Limited | Medicaments |
US5110810A (en) * | 1991-02-08 | 1992-05-05 | Virginia Commonwealth University | Method of using dehydroepiandrosterone and dehydroepiandrosterone-sulfate as inhibitors of platelet aggregation |
US5162198A (en) * | 1991-02-08 | 1992-11-10 | Virginia Commonwealth University | Method of using dehydroepiandrosterone and dehydroepiandrosterone-sulfate as inhibitors of thrombuxane production and platelet aggregation |
US5266312A (en) * | 1992-01-07 | 1993-11-30 | National Jewis Center For Immunology And Respiratory Medicine | Method for treating a steroid resistant condition via administration of gamma interferon |
EP0627921B1 (de) * | 1992-02-24 | 2000-05-31 | East Carolina University | Verfahren zur hemmung der karzinogenese durch behandlung mit dehydroepiandrosteron und dessen analoge |
US6093706A (en) * | 1992-03-04 | 2000-07-25 | Bioresponse, L.L.C. | Combined dehydroepiandrosterone and retinoid therapy for epithelial disorders |
US5686438A (en) * | 1993-03-09 | 1997-11-11 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
ATE275957T1 (de) * | 1993-01-19 | 2004-10-15 | Endorech Inc | Therapeutische verwendungen und verabreichungsysteme von dehydroepiandrosteron |
CA2153895A1 (en) * | 1993-03-09 | 1994-09-15 | Raymond A. Daynes | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
US5811418A (en) * | 1993-03-09 | 1998-09-22 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
US5635496A (en) * | 1993-03-09 | 1997-06-03 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
US5407927A (en) * | 1993-04-16 | 1995-04-18 | The Regents Of The University Of California | Treatment of mild depression and restoration of IGF-I levels in aging by dehydroepiandrosterone |
EP0796112A4 (de) * | 1994-11-30 | 1999-12-01 | Amur Research Corp | Phosphocholin-arzneistoffderivate |
US5660835A (en) * | 1995-02-24 | 1997-08-26 | East Carolina University | Method of treating adenosine depletion |
US20020032160A1 (en) * | 1995-02-24 | 2002-03-14 | Nyce Jonathan W. | Compositions & formulations with an epiandrosterone or a ubiquinone & kits & their use for treatment of asthma symptoms & for reducing adenosine/adenosine receptor levels |
US5859000A (en) * | 1995-06-07 | 1999-01-12 | University Of Utah Research Foundation | Method for reducing mast cell mediated allergic reactions |
US5767278A (en) * | 1995-10-06 | 1998-06-16 | Geron Corporation | Telomerase inhibitors |
EP1806131A3 (de) * | 1996-07-22 | 2007-08-01 | Renovo Limited | Verwendung von Sex-Steroid-Funktionsmodulatoren zur Behandlung von Wunden und fibrotischen Erkrankungen |
US5861391A (en) * | 1997-01-29 | 1999-01-19 | Research Development Foundation | Use of dehydroepiandrosterone to treat primary adrenal insufficiency and Addison's disease |
US20030013772A1 (en) * | 2000-02-23 | 2003-01-16 | Murphy Michael A. | Composition, synthesis and therapeutic applications of polyamines |
AU763307B2 (en) * | 1998-02-04 | 2003-07-17 | Charlotte-Mecklenburg Hospital Authority | Androsterone derivatives for inhibiting DNA binding of AP-1 and airway smooth muscle proliferation |
US7521068B2 (en) * | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
PT1283036E (pt) * | 1998-11-13 | 2008-03-06 | Jagotec Ag | Inalador de pó seco de dose múltipla com um reservatório de pó |
CN101543500A (zh) * | 1999-03-18 | 2009-09-30 | 基因实验室技术公司 | Dhea制剂及方法 |
US6428769B1 (en) * | 1999-05-04 | 2002-08-06 | Aradigm Corporation | Acute testosterone administration |
US20020010128A1 (en) * | 2000-04-13 | 2002-01-24 | Parks Thomas P. | Treatment of hyperproliferative, inflammatory and related mucocutaneous disorders using inhibitors of mevalonate synthesis and metabolism |
US7381713B2 (en) * | 2000-12-04 | 2008-06-03 | Sioan-Kettering Institute For Cancer Research | Treatment of cancer by reduction of intracellular energy and pyrimidines |
US20030216329A1 (en) * | 2001-04-24 | 2003-11-20 | Robinson Cynthia B. | Composition, formulations & kit for treatment of respiratory & lung disease with dehydroepiandrosterone(s) steroid & an anti-muscarinic agent(s) |
AU2002303425A1 (en) * | 2001-04-24 | 2002-11-05 | Epigenesis Pharmaceuticals, Inc. | Composition, formulations and kit for treatment of respiratory and lung disease with non-glucocorticoid steroids and/or ubiquinone and a bronchodilating agent |
US20030138434A1 (en) * | 2001-08-13 | 2003-07-24 | Campbell Robert L. | Agents for enhancing the immune response |
US7405207B2 (en) * | 2002-06-17 | 2008-07-29 | Epigenesis Pharmaceuticals, Inc. | Nebulizer formulations of dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereof |
-
2003
- 2003-06-17 BR BR0311883-5A patent/BR0311883A/pt not_active IP Right Cessation
- 2003-06-17 CA CA002491846A patent/CA2491846A1/en not_active Abandoned
- 2003-06-17 KR KR1020047020469A patent/KR20060011784A/ko active IP Right Grant
- 2003-06-17 JP JP2004525996A patent/JP2005537296A/ja active Pending
- 2003-06-17 BR BR0311885-1A patent/BR0311885A/pt not_active IP Right Cessation
- 2003-06-17 CN CNA038136813A patent/CN1681520A/zh active Pending
- 2003-06-17 JP JP2004512683A patent/JP2005530820A/ja active Pending
- 2003-06-17 KR KR1020047020590A patent/KR101005819B1/ko not_active IP Right Cessation
- 2003-06-17 CN CNB038136910A patent/CN100540007C/zh not_active Expired - Fee Related
- 2003-06-17 MX MXPA04012720A patent/MXPA04012720A/es active IP Right Grant
- 2003-06-17 WO PCT/US2003/018944 patent/WO2004012653A2/en active IP Right Grant
- 2003-06-17 EP EP03766816A patent/EP1513509A4/de not_active Withdrawn
- 2003-06-17 IL IL16537803A patent/IL165378A0/xx unknown
- 2003-06-17 AU AU2003269889A patent/AU2003269889B2/en not_active Ceased
- 2003-06-17 EP EP03751776A patent/EP1553954A4/de not_active Withdrawn
- 2003-06-17 WO PCT/US2003/018945 patent/WO2003105775A2/en active IP Right Grant
- 2003-06-17 IL IL16529103A patent/IL165291A0/xx unknown
- 2003-06-17 CA CA002489124A patent/CA2489124A1/en not_active Abandoned
- 2003-06-17 AU AU2003276836A patent/AU2003276836B2/en not_active Ceased
- 2003-06-17 MX MXPA04012728A patent/MXPA04012728A/es not_active Application Discontinuation
-
2008
- 2008-09-25 US US12/238,403 patent/US20090087389A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1553954A4 (de) | 2009-12-23 |
JP2005537296A (ja) | 2005-12-08 |
WO2004012653A2 (en) | 2004-02-12 |
EP1553954A2 (de) | 2005-07-20 |
BR0311883A (pt) | 2005-04-05 |
CA2491846A1 (en) | 2003-12-24 |
BR0311885A (pt) | 2005-04-05 |
EP1513509A4 (de) | 2009-05-27 |
IL165291A0 (en) | 2005-12-18 |
AU2003276836A1 (en) | 2004-02-23 |
AU2003276836B2 (en) | 2007-05-10 |
KR20050037515A (ko) | 2005-04-22 |
KR20060011784A (ko) | 2006-02-03 |
AU2003269889A1 (en) | 2003-12-31 |
KR101005819B1 (ko) | 2011-01-05 |
MXPA04012720A (es) | 2007-03-23 |
EP1513509A2 (de) | 2005-03-16 |
AU2003269889B2 (en) | 2007-04-19 |
WO2003105775A3 (en) | 2004-04-08 |
MXPA04012728A (es) | 2006-02-02 |
CN100540007C (zh) | 2009-09-16 |
CN1681520A (zh) | 2005-10-12 |
JP2005530820A (ja) | 2005-10-13 |
CA2489124A1 (en) | 2004-12-02 |
US20090087389A1 (en) | 2009-04-02 |
WO2004012653A3 (en) | 2004-07-08 |
WO2003105775A2 (en) | 2003-12-24 |
CN1658884A (zh) | 2005-08-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL165378A0 (en) | Nebulizer formulations of dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereof | |
MXPA02011311A (es) | Composicion novedosa. | |
IL167900A (en) | Use of betamimetics to prepare a medical preparation for the treatment of chronic obstructive pulmonary disease | |
EP1773374A4 (de) | Mittel mit fgf2 als wirkstoff zur behandlung und prävention von asthma und chronisch obstruktiver lungenerkrankung | |
AU2002256359A1 (en) | Antisense and anti-inflammatory based compositions to treat respiratory disorders | |
AP2002002590A0 (en) | Pyrimidinyl carboxamides useful as inhibitors of PDE4 isozymes. | |
EP1461076A4 (de) | Verfahren und zusammensetzungen zur behandlung von läsionen des respiratorischen epithels | |
WO2004043392A3 (en) | Mucin synthesis inhibitors | |
ZA200609141B (en) | Compositions for Inhalation therapy and methods of use | |
EP1478438A4 (de) | Verfahren und zusammensetzungen zur behandlung von asthma und verwandten krankheiten | |
EP1765331A4 (de) | Verfahren und zusammensetzungen zur behandlung von lungenerkrankungen | |
AU2003260484A1 (en) | Method for improving the ability of patients suffering from lung diseases to participate in and benefit from pulmonary rehabilitation programs | |
WO2004113286A3 (en) | Mucin synthesis inhibitors | |
WO2005099720A3 (en) | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a glucocorticosteroid for treatment of asthma, chronic obstructive pulmonary disease or allergic rhinitis | |
WO2005011608A3 (en) | PHARMACEUTICAL COMPOSITION COMPRISING A NON-GLUCOCORTICOID STEROID AND A cAMP INHIBITOR | |
WO2005011604A3 (en) | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease | |
MXPA04007294A (es) | Composicion para inhalacion. | |
WO2005011616A3 (en) | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a cromone for treatment of asthma or chronic obstructive pulmonary disease | |
EP1651170A4 (de) | Kombination von dehydroepiandrosteron oder dehydroepiandrosteron-sulfat mit einem anticholinergischen bronchodilatator zur behandlung von asthma oder chronisch obstruktiver lungenerkrankung | |
SI1216047T1 (sl) | Kombinacija loteprednola in agonistov beta2-adrenoceptorja in njena uporaba za zdravljenje bronhialne astme | |
AU4335901A (en) | Novel therapeutic treatment of chronic obstructive pulmonary disease | |
WO2005011603A3 (en) | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease | |
IL165574A0 (en) | Compositions for the transport of therapeutic molecules into the lungs and use thereof for the treatment of lung cancers and pulmonary diseases | |
WO2005011613A3 (en) | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a lipoxygenase inhibitor for treatment of asthma or chronic obstructive pulmonary disease | |
WO2003011294A3 (en) | Mucin synthesis inhibitors |