IL159548A0 - Use of thiazole derivatives for preparing a medicine for protecting mitochondria - Google Patents
Use of thiazole derivatives for preparing a medicine for protecting mitochondriaInfo
- Publication number
- IL159548A0 IL159548A0 IL15954802A IL15954802A IL159548A0 IL 159548 A0 IL159548 A0 IL 159548A0 IL 15954802 A IL15954802 A IL 15954802A IL 15954802 A IL15954802 A IL 15954802A IL 159548 A0 IL159548 A0 IL 159548A0
- Authority
- IL
- Israel
- Prior art keywords
- sup
- hydrogen atom
- alkyl
- medicine
- independently represent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Detergent Compositions (AREA)
- Saccharide Compounds (AREA)
- Accessory Of Washing/Drying Machine, Commercial Washing/Drying Machine, Other Washing/Drying Machine (AREA)
- Cleaning By Liquid Or Steam (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0109979A FR2827772B1 (fr) | 2001-07-26 | 2001-07-26 | Utilisation de derives de thiazoles pour preparer un medicament destine a proteger les mitochondries |
PCT/FR2002/002660 WO2003009843A1 (fr) | 2001-07-26 | 2002-07-25 | Utilisation de derives de thiazoles pour preparer un medicament destine a proteger les mithochondries |
Publications (1)
Publication Number | Publication Date |
---|---|
IL159548A0 true IL159548A0 (en) | 2004-06-01 |
Family
ID=8865922
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15954802A IL159548A0 (en) | 2001-07-26 | 2002-07-25 | Use of thiazole derivatives for preparing a medicine for protecting mitochondria |
IL159548A IL159548A (en) | 2001-07-26 | 2003-12-24 | Use of thiazole history in the preparation of a drug that protects the mitochondria |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL159548A IL159548A (en) | 2001-07-26 | 2003-12-24 | Use of thiazole history in the preparation of a drug that protects the mitochondria |
Country Status (26)
Country | Link |
---|---|
US (3) | US7345066B2 (de) |
EP (1) | EP1414447B1 (de) |
JP (1) | JP4491229B2 (de) |
KR (1) | KR20040030843A (de) |
CN (1) | CN1533276B (de) |
AT (1) | ATE333876T1 (de) |
AU (1) | AU2002341008B8 (de) |
BR (1) | BR0211423A (de) |
CA (1) | CA2455635C (de) |
CY (1) | CY1106212T1 (de) |
DE (1) | DE60213424T2 (de) |
DK (1) | DK1414447T3 (de) |
ES (1) | ES2268099T3 (de) |
FR (1) | FR2827772B1 (de) |
HK (1) | HK1069326A1 (de) |
HU (2) | HU228783B1 (de) |
IL (2) | IL159548A0 (de) |
IS (1) | IS2366B (de) |
MX (1) | MXPA04000752A (de) |
NO (1) | NO334797B1 (de) |
NZ (1) | NZ530368A (de) |
PL (1) | PL206706B1 (de) |
PT (1) | PT1414447E (de) |
RU (1) | RU2297832C2 (de) |
TW (1) | TWI309568B (de) |
WO (1) | WO2003009843A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7291641B2 (en) * | 1999-10-11 | 2007-11-06 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments |
US7101917B2 (en) | 2003-04-14 | 2006-09-05 | Hoffmann-La Roche Inc. | Mitochrondrial permeability transition pore affinity labels and modulators |
JP5495206B2 (ja) | 2006-10-24 | 2014-05-21 | コンジエニア・ソシエタ・ア・レスポンサビリタ・リミタータ | 変性性組織障害をmptの阻害により防止するための薬剤としてのフェニル置換マレイミド |
KR100970814B1 (ko) * | 2009-06-01 | 2010-07-16 | 주식회사 동아지질 | 석션 드레인 공법에 사용되는 배수재 연결구 |
JP6958860B2 (ja) | 2017-11-07 | 2021-11-02 | 学校法人自治医科大学 | ミトコンドリアの機能障害の改善剤、及びミトコンドリアの機能障害に起因する疾患又は症状の予防又は治療薬、並びにそれらの用途 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4914207A (en) * | 1989-05-09 | 1990-04-03 | Pfizer Inc. | Arylthiazolylimidazoles |
ATE147074T1 (de) * | 1990-09-25 | 1997-01-15 | Rhone Poulenc Rorer Int | Verbindungen welche antihypertensive und antiischemische eigenschaften besitzen |
HU9502843D0 (en) * | 1995-09-29 | 1995-11-28 | Livigene Ltd | Pharmaceutical composition |
FR2764889B1 (fr) * | 1997-06-20 | 2000-09-01 | Sod Conseils Rech Applic | Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
AU8875798A (en) * | 1997-08-29 | 1999-03-22 | Proteus Molecular Design Ltd | Meta-benzamidine derivatives as serin protease inhibitors |
US6518292B1 (en) * | 1999-03-12 | 2003-02-11 | Bristol-Myers Squibb Co. | Heterocyclic aromatic compounds usefuls as growth hormone secretagogues |
DE60022508T2 (de) * | 1999-06-14 | 2006-06-08 | Eli Lilly And Co., Indianapolis | Inhibitoren von serin proteasen |
TWI292316B (en) * | 1999-10-11 | 2008-01-11 | Sod Conseils Rech Applic | Pharmaceutical composition of thiazole derivatives intended to inhibit mao and/or lipidic peroxidation and/or to act as modulators of sodium channels and the use thereof |
FR2800615B1 (fr) * | 1999-11-05 | 2002-05-03 | Sod Conseils Rech Applic | Produit comprenant au moins une substance inhibitrice des no synthases en association avec au moins une substance inhibitrice des phospholipases a2 |
-
2000
- 2000-07-13 HU HU0500484A patent/HU228783B1/hu unknown
-
2001
- 2001-07-26 FR FR0109979A patent/FR2827772B1/fr not_active Expired - Lifetime
-
2002
- 2002-07-18 TW TW091116026A patent/TWI309568B/zh not_active IP Right Cessation
- 2002-07-25 BR BR0211423-2A patent/BR0211423A/pt not_active Application Discontinuation
- 2002-07-25 CN CN028145097A patent/CN1533276B/zh not_active Expired - Fee Related
- 2002-07-25 DK DK02774830T patent/DK1414447T3/da active
- 2002-07-25 HU HU0500557A patent/HU229425B1/hu not_active IP Right Cessation
- 2002-07-25 PL PL368315A patent/PL206706B1/pl unknown
- 2002-07-25 EP EP02774830A patent/EP1414447B1/de not_active Expired - Lifetime
- 2002-07-25 RU RU2004105653/15A patent/RU2297832C2/ru not_active IP Right Cessation
- 2002-07-25 MX MXPA04000752A patent/MXPA04000752A/es active IP Right Grant
- 2002-07-25 IL IL15954802A patent/IL159548A0/xx unknown
- 2002-07-25 NZ NZ530368A patent/NZ530368A/en not_active IP Right Cessation
- 2002-07-25 AU AU2002341008A patent/AU2002341008B8/en not_active Ceased
- 2002-07-25 US US10/483,823 patent/US7345066B2/en not_active Expired - Fee Related
- 2002-07-25 DE DE60213424T patent/DE60213424T2/de not_active Expired - Lifetime
- 2002-07-25 PT PT02774830T patent/PT1414447E/pt unknown
- 2002-07-25 JP JP2003515236A patent/JP4491229B2/ja not_active Expired - Fee Related
- 2002-07-25 CA CA2455635A patent/CA2455635C/fr not_active Expired - Fee Related
- 2002-07-25 AT AT02774830T patent/ATE333876T1/de active
- 2002-07-25 WO PCT/FR2002/002660 patent/WO2003009843A1/fr active IP Right Grant
- 2002-07-25 ES ES02774830T patent/ES2268099T3/es not_active Expired - Lifetime
- 2002-07-25 KR KR10-2004-7000996A patent/KR20040030843A/ko not_active Application Discontinuation
-
2003
- 2003-12-24 IL IL159548A patent/IL159548A/en not_active IP Right Cessation
-
2004
- 2004-01-09 IS IS7100A patent/IS2366B/is unknown
- 2004-01-21 NO NO20040280A patent/NO334797B1/no not_active IP Right Cessation
-
2005
- 2005-03-07 HK HK05101934.2A patent/HK1069326A1/xx not_active IP Right Cessation
-
2006
- 2006-10-23 CY CY20061101513T patent/CY1106212T1/el unknown
-
2007
- 2007-02-20 US US11/708,526 patent/US20070185174A1/en not_active Abandoned
- 2007-08-16 US US11/894,004 patent/US20080039451A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69919897D1 (en) | 4-oxo-1,4-dihydro-3-chinolincarboxamide als antivirale mittel | |
HUP0303037A2 (hu) | Alzheimer-kór kezelésére alkalmas vegyületek és ezeket tartalmazó gyógyszerkészítmények | |
DK1389617T3 (da) | Heterocyclisk forbindelse og antitumormiddel indeholdende denne som den aktive bestanddel | |
TW200420542A (en) | A compound having TGF β inhibition activity and a medicinal composition containing the same | |
AP1753A (en) | Thiophene derivatives as antiviral agents for flavvivirus infection | |
NO20015172L (no) | 1-metyl-erytromycin-derivater | |
HK1069326A1 (en) | Use of thiazole derivatives for preparing a medicine for protecting mitochondria | |
WO2005046672A3 (fr) | Utilisation d’inhibiteurs de glucosidase pour une therapie de la mucoviscidose | |
DK0700914T3 (da) | Campththecinderivater, deres fremstilling og antitumormidler | |
ATE243213T1 (de) | Silizium-enthaltende ascorbinsäurederivate | |
BG106156A (en) | Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives | |
MXPA04000371A (es) | 6- (2-tolil) - triazolopirimidinas substituidas. | |
EA200600608A1 (ru) | Производные имидазопиридина как ингибиторы индуцируемой no-синтазы | |
CO5200761A1 (es) | Nuevos derivados de equinocandina, su procedimiento de preparacion y su aplicacion como antifungicos | |
ZA928876B (en) | Thiazole derivatives. | |
CO5210951A1 (es) | Mezclas fungicidas sinergicas de una azolopirimidina y una fenoxiamida inhibidora de la biosisntesis de melanina | |
TW200508211A (en) | 2-naphthylimino-1,3-thiazine derivatives | |
ES2102774T3 (es) | Indolsulfonamidas como agentes antitumorales. | |
NO20053117L (no) | Cyklopenta[c]isoksazol-3-aminer anvendt som materialbeskyttelsesmidler.. | |
DK163922C (da) | 2,3-dihydro-3-phenyl-2-benzofuranonderivater, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem | |
TW200621740A (en) | Compound for treating hepatitis B and composition thereof | |
MXPA03005556A (es) | Derivados de 1,1-dioxo-1,2-benzotiacina-3-carboxamidas, metodo para prepararlos y composiciones farmaceuticas que los contienen. | |
MY120189A (en) | Sultam and sultone derived oxazolidinones |