IL159273A0 - Transdermal delivery system for sustained release of polypeptides - Google Patents

Transdermal delivery system for sustained release of polypeptides

Info

Publication number
IL159273A0
IL159273A0 IL15927303A IL15927303A IL159273A0 IL 159273 A0 IL159273 A0 IL 159273A0 IL 15927303 A IL15927303 A IL 15927303A IL 15927303 A IL15927303 A IL 15927303A IL 159273 A0 IL159273 A0 IL 159273A0
Authority
IL
Israel
Prior art keywords
polypeptides
delivery system
sustained release
transdermal delivery
transdermal
Prior art date
Application number
IL15927303A
Other languages
English (en)
Original Assignee
Transpharma Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transpharma Medical Ltd filed Critical Transpharma Medical Ltd
Priority to IL15927303A priority Critical patent/IL159273A0/xx
Publication of IL159273A0 publication Critical patent/IL159273A0/xx
Priority to CA002547621A priority patent/CA2547621A1/fr
Priority to EP04801605A priority patent/EP1691823B1/fr
Priority to JP2006543717A priority patent/JP2007513939A/ja
Priority to PCT/IL2004/001119 priority patent/WO2005056075A2/fr
Priority to IL175878A priority patent/IL175878A/en
Priority to US10/580,875 priority patent/US20070287949A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00765Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452Skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL15927303A 2003-12-09 2003-12-09 Transdermal delivery system for sustained release of polypeptides IL159273A0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IL15927303A IL159273A0 (en) 2003-12-09 2003-12-09 Transdermal delivery system for sustained release of polypeptides
CA002547621A CA2547621A1 (fr) 2003-12-09 2004-12-09 Systeme transdermique pour administration prolongee de polypeptides
EP04801605A EP1691823B1 (fr) 2003-12-09 2004-12-09 Systeme transdermique pour administration prolongee de polypeptides
JP2006543717A JP2007513939A (ja) 2003-12-09 2004-12-09 ポリペプチドの持続性送達用経皮システム
PCT/IL2004/001119 WO2005056075A2 (fr) 2003-12-09 2004-12-09 Systeme transdermique pour administration prolongee de polypeptides
IL175878A IL175878A (en) 2003-12-09 2006-05-23 Skin Transduction System for Prolonged Transfer of Polypeptides
US10/580,875 US20070287949A1 (en) 2003-12-09 2007-03-15 Transdermal System for Sustained Delivery of Polypeptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL15927303A IL159273A0 (en) 2003-12-09 2003-12-09 Transdermal delivery system for sustained release of polypeptides

Publications (1)

Publication Number Publication Date
IL159273A0 true IL159273A0 (en) 2004-06-01

Family

ID=33485335

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15927303A IL159273A0 (en) 2003-12-09 2003-12-09 Transdermal delivery system for sustained release of polypeptides
IL175878A IL175878A (en) 2003-12-09 2006-05-23 Skin Transduction System for Prolonged Transfer of Polypeptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL175878A IL175878A (en) 2003-12-09 2006-05-23 Skin Transduction System for Prolonged Transfer of Polypeptides

Country Status (6)

Country Link
US (1) US20070287949A1 (fr)
EP (1) EP1691823B1 (fr)
JP (1) JP2007513939A (fr)
CA (1) CA2547621A1 (fr)
IL (2) IL159273A0 (fr)
WO (1) WO2005056075A2 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1499255B1 (fr) 2002-04-19 2015-07-22 Syneron Medical Ltd. Administration de medicaments et extraction d'analyte par voie transdermique a l'aide d'un appareil tenu a la main
EP1742588B1 (fr) 2004-04-01 2016-10-19 The General Hospital Corporation Appareil de traitement dermatologique et remodelage de tissus
CA2587780A1 (fr) 2004-11-18 2006-05-26 Transpharma Medical Ltd. Production de micro-canaux associes et iontophorese pour une administration transdermique d'agents pharmaceutiques
CA2610757A1 (fr) * 2005-06-10 2006-12-14 Transpharma Medical, Ltd. Timbre transdermique pour la delivrance de medicaments
US20070009542A1 (en) * 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
EP2008598A1 (fr) * 2007-06-29 2008-12-31 Edward A. Loeser Instrument électrochirurgical à fibres composites
CA2704740C (fr) * 2007-10-09 2016-05-17 Transpharma Ltd. Fixation magnetique d'un timbre transdermique
WO2009050718A2 (fr) * 2007-10-17 2009-04-23 Transpharma Medical Ltd. Vérification de la vitesse de dissolution
WO2009072108A2 (fr) 2007-12-05 2009-06-11 Syneron Medical Ltd. Applicateur d'énergie électromagnétique jetable et son procédé d'utilisation
EP2303247A4 (fr) * 2008-07-21 2012-08-01 Syneron Medical Ltd Système transdermique de délivrance prolongée d'incrétines et de peptides mimétiques de l'incrétine
US8357150B2 (en) 2009-07-20 2013-01-22 Syneron Medical Ltd. Method and apparatus for fractional skin treatment
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
ES2461619T3 (es) 2009-02-25 2014-05-20 Syneron Medical Ltd. Rejuvenecimiento eléctrico de la piel
EP2359877A1 (fr) * 2010-02-11 2011-08-24 Universidad de Salamanca Matrice d'administration de médicament de cicatrisation et de vascularisation biocompatible
MX342898B (es) 2010-05-12 2016-10-18 Radius Health Inc * Regimen terapéutico de la sal de diclorhidrato del (r) -6-(2-(etil (4-2(etilamino) etil) bencil) amino)-4-metoxifenil)-5, 6,7,8-tetrahidronaftaleno-2-ol.
ES2550319T3 (es) 2010-09-28 2015-11-06 Radius Health, Inc Moduladores selectivos del receptor de andrógenos
CN104080441B (zh) 2011-11-30 2020-02-28 3M创新有限公司 包括肽治疗剂和氨基酸的微针装置、制备和使用其的方法
US20150094259A1 (en) * 2012-03-13 2015-04-02 University Of Kwazulu-Natal Transdermal Delivery Devices
WO2014008369A1 (fr) * 2012-07-03 2014-01-09 Massachusetts Institute Of Technology Implants crâniens perméables aux rayons x pour applications neurales
EP3137111A4 (fr) * 2014-05-02 2017-11-22 The Research Foundation of the State University of New York Compositions et méthodes d'administration de vaccins intradermiques
AU2016256470B2 (en) 2015-04-29 2020-10-15 Radius Pharmaceuticals, Inc. Methods of treating cancer
LT3474841T (lt) 2016-06-22 2022-06-10 Ellipses Pharma Ltd Ar+ krūties vėžio gydymo būdai
LT3565542T (lt) 2017-01-05 2024-07-10 Radius Pharmaceuticals, Inc. Polimorfinės rad1901-2hcl formos
WO2018183016A1 (fr) * 2017-03-30 2018-10-04 Dow Global Technologies Llc Film autonome
EP3384904A1 (fr) * 2017-04-03 2018-10-10 tesa Labtec GmbH Préparation pharmaceutique pour administration dermique
CA3099782A1 (fr) * 2018-05-11 2019-11-14 North Carolina State University Matrices d'hydrogel biosensibles et procedes d'utilisation
CN112423844B (zh) 2018-07-04 2024-08-13 雷迪厄斯制药公司 Rad1901-2hcl的多晶型形式

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5087240A (en) * 1983-08-18 1992-02-11 Drug Delivery Systems Inc. Transdermal drug patch with conductive fibers
US4684558A (en) * 1986-06-30 1987-08-04 Nepera Inc. Adhesive polyethylene oxide hydrogel sheet and its production
US5961482A (en) * 1986-07-25 1999-10-05 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
AU609769B2 (en) * 1987-02-10 1991-05-09 Drug Delivery Systems Inc. Electrolytic transdermal delivery of proteins
US4940456A (en) * 1987-02-10 1990-07-10 Dan Sibalis Electrolytic transdermal delivery of proteins
US5008110A (en) * 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
EP0429842B1 (fr) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide
US5833665A (en) * 1990-06-14 1998-11-10 Integra Lifesciences I, Ltd. Polyurethane-biopolymer composite
US5158537A (en) * 1990-10-29 1992-10-27 Alza Corporation Iontophoretic delivery device and method of hydrating same
IE920763A1 (en) * 1991-03-11 1992-09-23 Alza Corp Iontophoretic delivery device and method of making same
JPH06500802A (ja) * 1991-06-14 1994-01-27 アムジエン・インコーポレーテツド コラーゲンフィルムによるタンパクのドラッグ・デリバリー
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
AU664214B2 (en) * 1991-11-13 1995-11-09 Elan Corporation, Plc Drug delivery device
IL105529A0 (en) * 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
US5885211A (en) * 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5466465A (en) * 1993-12-30 1995-11-14 Harrogate Holdings, Limited Transdermal drug delivery system
US5837281A (en) * 1995-03-17 1998-11-17 Takeda Chemical Industries, Ltd. Stabilized interface for iontophoresis
US5983130A (en) * 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
US5906830A (en) * 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
US20010006645A1 (en) * 1996-10-28 2001-07-05 Jane A. Norton Method for transdermal drug delivery
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US6660295B2 (en) * 1997-09-30 2003-12-09 Alza Corporation Transdermal drug delivery device package with improved drug stability
US6775569B2 (en) 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
US20040258703A1 (en) * 1997-11-14 2004-12-23 The Government Of The Us, As Represented By The Secretary Of The Army Skin-active adjuvants for transcutaneous immunization
JP4154017B2 (ja) * 1997-12-30 2008-09-24 久光製薬株式会社 イオントフォレーシス装置および薬物ユニット
US6022316A (en) * 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
US6173202B1 (en) * 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6611706B2 (en) * 1998-11-09 2003-08-26 Transpharma Ltd. Monopolar and bipolar current application for transdermal drug delivery and analyte extraction
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6708060B1 (en) * 1998-11-09 2004-03-16 Transpharma Ltd. Handheld apparatus and method for transdermal drug delivery and analyte extraction
US6597946B2 (en) * 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
US5983135A (en) * 1998-12-24 1999-11-09 Avrahami; Zohar Transdermal delivery of fine powders
WO2000061184A2 (fr) * 1999-04-08 2000-10-19 Glenn Gregory M Formulation seche pour immunisation transcutanee
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6565879B1 (en) * 1999-12-16 2003-05-20 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers
US20040185055A1 (en) * 2001-03-19 2004-09-23 Glenn Gregory M Transcutaneous immunostimulation
US7005138B2 (en) * 2001-12-21 2006-02-28 Duramed Pharmaceuticals, Inc. Method of systematically delivering SSRIs
AU2003268376A1 (en) * 2002-08-30 2004-11-26 Watson Pharmaceuticals, Inc. Transdermal delivery systems and methods
WO2005041871A2 (fr) * 2003-10-24 2005-05-12 Alza Corporation Dispositif et procede d'amelioration de l'administration transdermique de medicament
WO2005044366A2 (fr) * 2003-10-31 2005-05-19 Alza Corporation Systeme et methode d'administration de vaccin transdermique
US20050208095A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
US20060177494A1 (en) * 2005-01-31 2006-08-10 Micheal Cormier Coated microprojections having reduced variability and method for producing same
US20060222640A1 (en) * 2005-03-29 2006-10-05 Boehringer Ingelheim International Gmbh New pharmaceutical compositions for treatment of thrombosis

Also Published As

Publication number Publication date
IL175878A0 (en) 2006-10-05
CA2547621A1 (fr) 2005-06-23
EP1691823B1 (fr) 2012-10-10
JP2007513939A (ja) 2007-05-31
US20070287949A1 (en) 2007-12-13
WO2005056075A3 (fr) 2006-02-02
IL175878A (en) 2014-06-30
EP1691823A4 (fr) 2009-07-08
EP1691823A2 (fr) 2006-08-23
WO2005056075A2 (fr) 2005-06-23

Similar Documents

Publication Publication Date Title
IL159273A0 (en) Transdermal delivery system for sustained release of polypeptides
AU2003221770A8 (en) Controlled release transdermal drug delivery
ZA200701263B (en) Controlled release delivery system for bioo-active agents
EP1807018A4 (fr) Systeme d'administration in situ de medicaments a liberation controlee
IL243302A0 (en) Patch to stick on skin for fentanyl administration
EP1720605A4 (fr) Systeme d'administration transdermique d'agents cosmetiques
EP1773240A4 (fr) Systeme d'administration de medicament a base de soie
EP1773439A4 (fr) Systeme de distribution de matiere
EP1768742A4 (fr) Systeme d'administration pour immunisation transdermique
TWI350176B (en) Controlled release delivery system for nasal applications
IL177785A0 (en) Nanocell drug delivery system
IL176971A0 (en) Transdermal delivery system for polynucleotides
PL1631255T3 (pl) System dostarczania leków
HK1074801A1 (en) Transdermal delivery system of gestodene
GB0517035D0 (en) Delivery system
EP1802346A4 (fr) Composition pharmaceutique à libération prolongée
AU2003260803A8 (en) Sustained release pharmaceutical composition
GB2422315B (en) Maggot delivery system
GB0426641D0 (en) Protein delivery system
AU2003212962A8 (en) Transdermal drug delivery systems
EP1478353A4 (fr) Composition pharmaceutique a liberation soutenue
PL377117A1 (pl) Układ dostarczania leku do podtrzymywanego dostarczania glipizydu
GB0401008D0 (en) Drug delivery system
AU2003230034A8 (en) Transdermal delivery device for the administration of fentanyl
EP1732555A4 (fr) Systeme d'administration d'un opioide