IL159273A0 - Transdermal delivery system for sustained release of polypeptides - Google Patents
Transdermal delivery system for sustained release of polypeptidesInfo
- Publication number
- IL159273A0 IL159273A0 IL15927303A IL15927303A IL159273A0 IL 159273 A0 IL159273 A0 IL 159273A0 IL 15927303 A IL15927303 A IL 15927303A IL 15927303 A IL15927303 A IL 15927303A IL 159273 A0 IL159273 A0 IL 159273A0
- Authority
- IL
- Israel
- Prior art keywords
- polypeptides
- delivery system
- sustained release
- transdermal delivery
- transdermal
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 230000037317 transdermal delivery Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/044—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL15927303A IL159273A0 (en) | 2003-12-09 | 2003-12-09 | Transdermal delivery system for sustained release of polypeptides |
EP04801605A EP1691823B1 (fr) | 2003-12-09 | 2004-12-09 | Systeme transdermique pour administration prolongee de polypeptides |
JP2006543717A JP2007513939A (ja) | 2003-12-09 | 2004-12-09 | ポリペプチドの持続性送達用経皮システム |
CA002547621A CA2547621A1 (fr) | 2003-12-09 | 2004-12-09 | Systeme transdermique pour administration prolongee de polypeptides |
PCT/IL2004/001119 WO2005056075A2 (fr) | 2003-12-09 | 2004-12-09 | Systeme transdermique pour administration prolongee de polypeptides |
IL175878A IL175878A (en) | 2003-12-09 | 2006-05-23 | Skin Transduction System for Prolonged Transfer of Polypeptides |
US10/580,875 US20070287949A1 (en) | 2003-12-09 | 2007-03-15 | Transdermal System for Sustained Delivery of Polypeptides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL15927303A IL159273A0 (en) | 2003-12-09 | 2003-12-09 | Transdermal delivery system for sustained release of polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
IL159273A0 true IL159273A0 (en) | 2004-06-01 |
Family
ID=33485335
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15927303A IL159273A0 (en) | 2003-12-09 | 2003-12-09 | Transdermal delivery system for sustained release of polypeptides |
IL175878A IL175878A (en) | 2003-12-09 | 2006-05-23 | Skin Transduction System for Prolonged Transfer of Polypeptides |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL175878A IL175878A (en) | 2003-12-09 | 2006-05-23 | Skin Transduction System for Prolonged Transfer of Polypeptides |
Country Status (6)
Country | Link |
---|---|
US (1) | US20070287949A1 (fr) |
EP (1) | EP1691823B1 (fr) |
JP (1) | JP2007513939A (fr) |
CA (1) | CA2547621A1 (fr) |
IL (2) | IL159273A0 (fr) |
WO (1) | WO2005056075A2 (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003089043A2 (fr) | 2002-04-19 | 2003-10-30 | Transpharma Medical Ltd. | Administration de medicaments et extraction d'analyte par voie transdermique a l'aide d'un appareil tenu a la main |
EP2343021A1 (fr) | 2004-04-01 | 2011-07-13 | The General Hospital Corporation | Procédé et appareil pour le traitement dermatologique et le remodelage des tissus |
EP1848498A4 (fr) | 2004-11-18 | 2009-12-16 | Transpharma Medical Ltd | Production de micro-canaux associes et iontophorese pour une administration transdermique d'agents pharmaceutiques |
US20080274166A1 (en) * | 2005-06-10 | 2008-11-06 | Transpharma Medical Ltd. | Patch for Transdermal Drug Delivery |
US20070009542A1 (en) * | 2005-07-05 | 2007-01-11 | Galit Levin | Method and device for transdermal immunization |
EP2008598A1 (fr) * | 2007-06-29 | 2008-12-31 | Edward A. Loeser | Instrument électrochirurgical à fibres composites |
JP5466161B2 (ja) * | 2007-10-09 | 2014-04-09 | トランスファーマ メディカル リミテッド | 磁気的なパッチ連結物 |
CA2696227A1 (fr) * | 2007-10-17 | 2009-04-23 | Transpharma Medical Ltd. | Verification de la vitesse de dissolution |
WO2009072108A2 (fr) | 2007-12-05 | 2009-06-11 | Syneron Medical Ltd. | Applicateur d'énergie électromagnétique jetable et son procédé d'utilisation |
CA2731236A1 (fr) * | 2008-07-21 | 2010-01-28 | Transpharma Medical Ltd. | Systeme transdermique de delivrance prolongee d'incretines et de peptides mimetiques de l'incretine |
US8357150B2 (en) | 2009-07-20 | 2013-01-22 | Syneron Medical Ltd. | Method and apparatus for fractional skin treatment |
US8606366B2 (en) | 2009-02-18 | 2013-12-10 | Syneron Medical Ltd. | Skin treatment apparatus for personal use and method for using same |
US9278230B2 (en) | 2009-02-25 | 2016-03-08 | Syneron Medical Ltd | Electrical skin rejuvenation |
EP2359877A1 (fr) * | 2010-02-11 | 2011-08-24 | Universidad de Salamanca | Matrice d'administration de médicament de cicatrisation et de vascularisation biocompatible |
LT2568806T (lt) | 2010-05-12 | 2016-09-26 | Radius Health, Inc. | Terapiniai režimai |
JP5965909B2 (ja) | 2010-09-28 | 2016-08-10 | ラジウス ヘルス,インコーポレイテッド | 選択的アンドロゲン受容体モジュレーター |
CA2857502C (fr) | 2011-11-30 | 2019-08-13 | 3M Innovative Properties Company | Dispositif a micro-aiguilles comprenant un agent therapeutique peptidique et un acide amine et ses procedes de fabrication et d'utilisation |
US20150094259A1 (en) * | 2012-03-13 | 2015-04-02 | University Of Kwazulu-Natal | Transdermal Delivery Devices |
US20150320560A1 (en) * | 2012-07-03 | 2015-11-12 | Massachusetts Institute Of Technology | Radiolucent cranial implants for neural applications |
US20170065534A1 (en) * | 2014-05-02 | 2017-03-09 | The Research Foundation For The State University Of New York | Compositions and methods for intradermal vaccine delivery |
IL310069A (en) | 2015-04-29 | 2024-03-01 | Radius Pharmaceuticals Inc | Cancer treatment methods |
KR102397890B1 (ko) | 2016-06-22 | 2022-05-12 | 일립시스 파마 리미티드 | Ar+ 유방암 치료 방법 |
WO2018129419A1 (fr) | 2017-01-05 | 2018-07-12 | Radius Pharmaceuticals, Inc. | Formes polymorphes de rad1901-2hcl |
WO2018183016A1 (fr) * | 2017-03-30 | 2018-10-04 | Dow Global Technologies Llc | Film autonome |
EP3384904A1 (fr) * | 2017-04-03 | 2018-10-10 | tesa Labtec GmbH | Préparation pharmaceutique pour administration dermique |
CA3099782A1 (fr) * | 2018-05-11 | 2019-11-14 | North Carolina State University | Matrices d'hydrogel biosensibles et procedes d'utilisation |
SG11202013177WA (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals Inc | Polymorphic forms of rad 1901-2hcl |
Family Cites Families (44)
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US5087240A (en) * | 1983-08-18 | 1992-02-11 | Drug Delivery Systems Inc. | Transdermal drug patch with conductive fibers |
US4684558A (en) * | 1986-06-30 | 1987-08-04 | Nepera Inc. | Adhesive polyethylene oxide hydrogel sheet and its production |
US5961482A (en) * | 1986-07-25 | 1999-10-05 | Rutgers, The State University Of New Jersey | Iontotherapeutic device and process and iontotherapeutic unit dose |
AU609769B2 (en) * | 1987-02-10 | 1991-05-09 | Drug Delivery Systems Inc. | Electrolytic transdermal delivery of proteins |
US4940456A (en) * | 1987-02-10 | 1990-07-10 | Dan Sibalis | Electrolytic transdermal delivery of proteins |
US5008110A (en) * | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
US5510418A (en) * | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
EP0429842B1 (fr) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide |
US5833665A (en) * | 1990-06-14 | 1998-11-10 | Integra Lifesciences I, Ltd. | Polyurethane-biopolymer composite |
US5158537A (en) * | 1990-10-29 | 1992-10-27 | Alza Corporation | Iontophoretic delivery device and method of hydrating same |
WO1992015365A1 (fr) * | 1991-03-11 | 1992-09-17 | Alza Corporation | Dispositif d'administration iontophoretique et son procede de production |
AU654574B2 (en) * | 1991-06-14 | 1994-11-10 | Amgen, Inc. | Collagen film drug delivery for proteins |
US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
DE69220808T2 (de) * | 1991-11-13 | 1998-01-02 | Elan Corp Plc | Vorrichtung zur verabreichung von heilmitteln |
IL105529A0 (en) * | 1992-05-01 | 1993-08-18 | Amgen Inc | Collagen-containing sponges as drug delivery for proteins |
US5885211A (en) * | 1993-11-15 | 1999-03-23 | Spectrix, Inc. | Microporation of human skin for monitoring the concentration of an analyte |
US5466465A (en) * | 1993-12-30 | 1995-11-14 | Harrogate Holdings, Limited | Transdermal drug delivery system |
US5837281A (en) * | 1995-03-17 | 1998-11-17 | Takeda Chemical Industries, Ltd. | Stabilized interface for iontophoresis |
US5983130A (en) * | 1995-06-07 | 1999-11-09 | Alza Corporation | Electrotransport agent delivery method and apparatus |
US5906830A (en) * | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
US20010006645A1 (en) * | 1996-10-28 | 2001-07-05 | Jane A. Norton | Method for transdermal drug delivery |
US5980898A (en) * | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
US6660295B2 (en) * | 1997-09-30 | 2003-12-09 | Alza Corporation | Transdermal drug delivery device package with improved drug stability |
US6775569B2 (en) * | 1997-11-05 | 2004-08-10 | Hisamitsu Pharmaceutical Co., Inc. | Electroporation device for in vivo delivery of therapeutic agents |
US20040258703A1 (en) * | 1997-11-14 | 2004-12-23 | The Government Of The Us, As Represented By The Secretary Of The Army | Skin-active adjuvants for transcutaneous immunization |
JP4154017B2 (ja) * | 1997-12-30 | 2008-09-24 | 久光製薬株式会社 | イオントフォレーシス装置および薬物ユニット |
US6022316A (en) * | 1998-03-06 | 2000-02-08 | Spectrx, Inc. | Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications |
US6173202B1 (en) * | 1998-03-06 | 2001-01-09 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
US6611706B2 (en) * | 1998-11-09 | 2003-08-26 | Transpharma Ltd. | Monopolar and bipolar current application for transdermal drug delivery and analyte extraction |
US6708060B1 (en) * | 1998-11-09 | 2004-03-16 | Transpharma Ltd. | Handheld apparatus and method for transdermal drug delivery and analyte extraction |
US6148232A (en) * | 1998-11-09 | 2000-11-14 | Elecsys Ltd. | Transdermal drug delivery and analyte extraction |
US6597946B2 (en) * | 1998-11-09 | 2003-07-22 | Transpharma Ltd. | Electronic card for transdermal drug delivery and analyte extraction |
US5983135A (en) * | 1998-12-24 | 1999-11-09 | Avrahami; Zohar | Transdermal delivery of fine powders |
AU4188100A (en) * | 1999-04-08 | 2000-11-14 | Gregory M. Glenn | Dry formulation for transcutaneous immunization |
US7133717B2 (en) * | 1999-08-25 | 2006-11-07 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery and diagnostic sampling |
US6565879B1 (en) * | 1999-12-16 | 2003-05-20 | Dermatrends, Inc. | Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers |
JP2004529906A (ja) * | 2001-03-19 | 2004-09-30 | イオマイ コーポレイシヨン | 経皮的免疫賦活 |
US7005138B2 (en) * | 2001-12-21 | 2006-02-28 | Duramed Pharmaceuticals, Inc. | Method of systematically delivering SSRIs |
WO2004098472A1 (fr) * | 2002-08-30 | 2004-11-18 | Watson Pharmaceuticals, Inc. | Systemes et techniques d'administration transdermique |
WO2005041871A2 (fr) * | 2003-10-24 | 2005-05-12 | Alza Corporation | Dispositif et procede d'amelioration de l'administration transdermique de medicament |
WO2005044366A2 (fr) * | 2003-10-31 | 2005-05-19 | Alza Corporation | Systeme et methode d'administration de vaccin transdermique |
US20050208095A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
WO2006083681A2 (fr) * | 2005-01-31 | 2006-08-10 | Alza Corporation | Microprojections recouvertes presentant une variabilite reduite et procede pour produire lesdites microprojections |
US20060222640A1 (en) * | 2005-03-29 | 2006-10-05 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions for treatment of thrombosis |
-
2003
- 2003-12-09 IL IL15927303A patent/IL159273A0/xx unknown
-
2004
- 2004-12-09 JP JP2006543717A patent/JP2007513939A/ja active Pending
- 2004-12-09 CA CA002547621A patent/CA2547621A1/fr not_active Abandoned
- 2004-12-09 WO PCT/IL2004/001119 patent/WO2005056075A2/fr active Application Filing
- 2004-12-09 EP EP04801605A patent/EP1691823B1/fr not_active Not-in-force
-
2006
- 2006-05-23 IL IL175878A patent/IL175878A/en not_active IP Right Cessation
-
2007
- 2007-03-15 US US10/580,875 patent/US20070287949A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IL175878A0 (en) | 2006-10-05 |
WO2005056075A2 (fr) | 2005-06-23 |
EP1691823B1 (fr) | 2012-10-10 |
US20070287949A1 (en) | 2007-12-13 |
IL175878A (en) | 2014-06-30 |
EP1691823A4 (fr) | 2009-07-08 |
EP1691823A2 (fr) | 2006-08-23 |
JP2007513939A (ja) | 2007-05-31 |
CA2547621A1 (fr) | 2005-06-23 |
WO2005056075A3 (fr) | 2006-02-02 |
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