IL159273A0 - Transdermal delivery system for sustained release of polypeptides - Google Patents
Transdermal delivery system for sustained release of polypeptidesInfo
- Publication number
- IL159273A0 IL159273A0 IL15927303A IL15927303A IL159273A0 IL 159273 A0 IL159273 A0 IL 159273A0 IL 15927303 A IL15927303 A IL 15927303A IL 15927303 A IL15927303 A IL 15927303A IL 159273 A0 IL159273 A0 IL 159273A0
- Authority
- IL
- Israel
- Prior art keywords
- polypeptides
- delivery system
- sustained release
- transdermal delivery
- transdermal
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 230000037317 transdermal delivery Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/044—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL15927303A IL159273A0 (en) | 2003-12-09 | 2003-12-09 | Transdermal delivery system for sustained release of polypeptides |
CA002547621A CA2547621A1 (en) | 2003-12-09 | 2004-12-09 | Transdermal system for sustained delivery of polypeptides |
EP04801605A EP1691823B1 (en) | 2003-12-09 | 2004-12-09 | Transdermal system for sustained delivery of polypeptides |
JP2006543717A JP2007513939A (ja) | 2003-12-09 | 2004-12-09 | ポリペプチドの持続性送達用経皮システム |
PCT/IL2004/001119 WO2005056075A2 (en) | 2003-12-09 | 2004-12-09 | Transdermal system for sustained delivery of polypeptides |
IL175878A IL175878A (en) | 2003-12-09 | 2006-05-23 | Skin Transduction System for Prolonged Transfer of Polypeptides |
US10/580,875 US20070287949A1 (en) | 2003-12-09 | 2007-03-15 | Transdermal System for Sustained Delivery of Polypeptides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL15927303A IL159273A0 (en) | 2003-12-09 | 2003-12-09 | Transdermal delivery system for sustained release of polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
IL159273A0 true IL159273A0 (en) | 2004-06-01 |
Family
ID=33485335
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15927303A IL159273A0 (en) | 2003-12-09 | 2003-12-09 | Transdermal delivery system for sustained release of polypeptides |
IL175878A IL175878A (en) | 2003-12-09 | 2006-05-23 | Skin Transduction System for Prolonged Transfer of Polypeptides |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL175878A IL175878A (en) | 2003-12-09 | 2006-05-23 | Skin Transduction System for Prolonged Transfer of Polypeptides |
Country Status (6)
Country | Link |
---|---|
US (1) | US20070287949A1 (xx) |
EP (1) | EP1691823B1 (xx) |
JP (1) | JP2007513939A (xx) |
CA (1) | CA2547621A1 (xx) |
IL (2) | IL159273A0 (xx) |
WO (1) | WO2005056075A2 (xx) |
Families Citing this family (27)
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WO2003089043A2 (en) | 2002-04-19 | 2003-10-30 | Transpharma Medical Ltd. | Handheld transdermal drug delivery and analyte extraction |
CA2579145C (en) | 2004-04-01 | 2023-06-27 | The General Hospital Corporation | Method and apparatus for dermatological treatment and tissue reshaping |
JP2008520331A (ja) | 2004-11-18 | 2008-06-19 | トランスファーマ メディカル リミテッド | 薬剤の経皮的送達のためのマイクロチャネル形成とイオントフォレーシスの組合せ |
EP1888001B1 (en) * | 2005-06-10 | 2014-08-06 | Syneron Medical Ltd. | Patch for transdermal drug delivery |
US20070009542A1 (en) * | 2005-07-05 | 2007-01-11 | Galit Levin | Method and device for transdermal immunization |
EP2008598A1 (en) * | 2007-06-29 | 2008-12-31 | Edward A. Loeser | Composite fiber electrosurgical instrument |
EP2200666B1 (en) * | 2007-10-09 | 2014-12-03 | Syneron Medical Ltd. | Magnetic patch coupling |
JP5612474B2 (ja) * | 2007-10-17 | 2014-10-22 | トランスファーマ メディカル リミテッド | 溶出速度の検証 |
EP2394594A1 (en) | 2007-12-05 | 2011-12-14 | Syneron Medical Ltd. | A disposable electromagnetic energy applicator and method of using it |
JP2011528709A (ja) * | 2008-07-21 | 2011-11-24 | トランスファーマ メディカル リミテッド | インクレチンおよびインクレチン模倣ペプチドの持続性送達用経皮システム |
US8357150B2 (en) | 2009-07-20 | 2013-01-22 | Syneron Medical Ltd. | Method and apparatus for fractional skin treatment |
US8606366B2 (en) | 2009-02-18 | 2013-12-10 | Syneron Medical Ltd. | Skin treatment apparatus for personal use and method for using same |
US9278230B2 (en) | 2009-02-25 | 2016-03-08 | Syneron Medical Ltd | Electrical skin rejuvenation |
EP2359877A1 (en) * | 2010-02-11 | 2011-08-24 | Universidad de Salamanca | Bicompatible vascularising and cicatrizing drug-delivery matrix |
ME02474B (me) | 2010-05-12 | 2017-02-20 | Radius Health Inc | Terapijski režimi |
US9133182B2 (en) | 2010-09-28 | 2015-09-15 | Radius Health, Inc. | Selective androgen receptor modulators |
EP2785327B1 (en) | 2011-11-30 | 2023-11-22 | Kindeva Drug Delivery L.P. | Microneedle device having a peptide therapeutic agent and an amino acid, methods of making and using the same |
WO2013136234A1 (en) * | 2012-03-13 | 2013-09-19 | University Of Kwazulu-Natal | Transdermal delivery devices |
WO2014008369A1 (en) * | 2012-07-03 | 2014-01-09 | Massachusetts Institute Of Technology | Radiolucent cranial implants for neural applications |
EP3137111A4 (en) * | 2014-05-02 | 2017-11-22 | The Research Foundation of the State University of New York | Compositions and methods for intradermal vaccine delivery |
RU2737496C2 (ru) | 2015-04-29 | 2020-12-01 | Радиус Фармасьютикалз, Инк. | Способы лечения рака |
JP7221699B2 (ja) | 2016-06-22 | 2023-02-14 | エリプセス ファーマ エルティーディー | Ar+乳癌の治療方法 |
FI3565542T3 (fi) | 2017-01-05 | 2024-06-24 | Radius Pharmaceuticals Inc | Rad1901-2hcl:n polymorfisia muotoja |
US10982175B2 (en) * | 2017-03-30 | 2021-04-20 | Dow Global Technologies Llc | Free standing film |
EP3384904A1 (en) * | 2017-04-03 | 2018-10-10 | tesa Labtec GmbH | Pharmaceutical preparation for dermal administration |
WO2019217954A1 (en) * | 2018-05-11 | 2019-11-14 | North Carolina State University | Bioresponsive hydrogel matrixes and methods of use |
US11643385B2 (en) | 2018-07-04 | 2023-05-09 | Radius Pharmaceuticals, Inc. | Polymorphic forms of RAD1901-2HCl |
Family Cites Families (44)
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US5087240A (en) * | 1983-08-18 | 1992-02-11 | Drug Delivery Systems Inc. | Transdermal drug patch with conductive fibers |
US4684558A (en) * | 1986-06-30 | 1987-08-04 | Nepera Inc. | Adhesive polyethylene oxide hydrogel sheet and its production |
US5961482A (en) * | 1986-07-25 | 1999-10-05 | Rutgers, The State University Of New Jersey | Iontotherapeutic device and process and iontotherapeutic unit dose |
AU609769B2 (en) * | 1987-02-10 | 1991-05-09 | Drug Delivery Systems Inc. | Electrolytic transdermal delivery of proteins |
US4940456A (en) * | 1987-02-10 | 1990-07-10 | Dan Sibalis | Electrolytic transdermal delivery of proteins |
US5008110A (en) * | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
US5510418A (en) * | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
EP0429842B1 (en) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5833665A (en) * | 1990-06-14 | 1998-11-10 | Integra Lifesciences I, Ltd. | Polyurethane-biopolymer composite |
US5158537A (en) * | 1990-10-29 | 1992-10-27 | Alza Corporation | Iontophoretic delivery device and method of hydrating same |
ZA921736B (en) * | 1991-03-11 | 1992-11-25 | Alza Corp | Iontophoretic delivery device and method of making same |
AU654574B2 (en) * | 1991-06-14 | 1994-11-10 | Amgen, Inc. | Collagen film drug delivery for proteins |
US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
DE69220808T2 (de) * | 1991-11-13 | 1998-01-02 | Elan Corp Plc | Vorrichtung zur verabreichung von heilmitteln |
IL105529A0 (en) * | 1992-05-01 | 1993-08-18 | Amgen Inc | Collagen-containing sponges as drug delivery for proteins |
US5885211A (en) * | 1993-11-15 | 1999-03-23 | Spectrix, Inc. | Microporation of human skin for monitoring the concentration of an analyte |
US5466465A (en) * | 1993-12-30 | 1995-11-14 | Harrogate Holdings, Limited | Transdermal drug delivery system |
US5837281A (en) * | 1995-03-17 | 1998-11-17 | Takeda Chemical Industries, Ltd. | Stabilized interface for iontophoresis |
US5983130A (en) * | 1995-06-07 | 1999-11-09 | Alza Corporation | Electrotransport agent delivery method and apparatus |
US5906830A (en) * | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
US20010006645A1 (en) * | 1996-10-28 | 2001-07-05 | Jane A. Norton | Method for transdermal drug delivery |
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EP1165132B1 (en) * | 1999-04-08 | 2011-10-19 | Intercell USA, Inc. | Dry formulation for transcutaneous immunization |
US7133717B2 (en) * | 1999-08-25 | 2006-11-07 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery and diagnostic sampling |
US6565879B1 (en) * | 1999-12-16 | 2003-05-20 | Dermatrends, Inc. | Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers |
WO2002074244A2 (en) * | 2001-03-19 | 2002-09-26 | Iomai Corporation | Transcutaneous immunostimulation |
US7005138B2 (en) * | 2001-12-21 | 2006-02-28 | Duramed Pharmaceuticals, Inc. | Method of systematically delivering SSRIs |
WO2004098472A1 (en) * | 2002-08-30 | 2004-11-18 | Watson Pharmaceuticals, Inc. | Transdermal delivery systems and methods |
AU2004285481A1 (en) * | 2003-10-24 | 2005-05-12 | Alza Corporation | Apparatus and method for enhancing transdermal drug delivery |
EP1680178A4 (en) * | 2003-10-31 | 2008-01-02 | Alza Corp | SYSTEM AND METHOD FOR THE TRANSDERMAL DISTRIBUTION OF A VACCINE |
US20050208095A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
CA2596075A1 (en) * | 2005-01-31 | 2006-08-10 | Alza Corporation | Coated microprojections having reduced variability and method for producing same |
US20060222640A1 (en) * | 2005-03-29 | 2006-10-05 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions for treatment of thrombosis |
-
2003
- 2003-12-09 IL IL15927303A patent/IL159273A0/xx unknown
-
2004
- 2004-12-09 WO PCT/IL2004/001119 patent/WO2005056075A2/en active Application Filing
- 2004-12-09 EP EP04801605A patent/EP1691823B1/en not_active Not-in-force
- 2004-12-09 JP JP2006543717A patent/JP2007513939A/ja active Pending
- 2004-12-09 CA CA002547621A patent/CA2547621A1/en not_active Abandoned
-
2006
- 2006-05-23 IL IL175878A patent/IL175878A/en not_active IP Right Cessation
-
2007
- 2007-03-15 US US10/580,875 patent/US20070287949A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IL175878A (en) | 2014-06-30 |
EP1691823A2 (en) | 2006-08-23 |
EP1691823A4 (en) | 2009-07-08 |
WO2005056075A2 (en) | 2005-06-23 |
EP1691823B1 (en) | 2012-10-10 |
CA2547621A1 (en) | 2005-06-23 |
JP2007513939A (ja) | 2007-05-31 |
IL175878A0 (en) | 2006-10-05 |
US20070287949A1 (en) | 2007-12-13 |
WO2005056075A3 (en) | 2006-02-02 |
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