IL157893A0 - Substituted dimethyl-[1-(1-phenyl-cyclohexyl)-piperidin-3-yl methyl]-amines and the use of the same as analgesics - Google Patents

Substituted dimethyl-[1-(1-phenyl-cyclohexyl)-piperidin-3-yl methyl]-amines and the use of the same as analgesics

Info

Publication number
IL157893A0
IL157893A0 IL15789302A IL15789302A IL157893A0 IL 157893 A0 IL157893 A0 IL 157893A0 IL 15789302 A IL15789302 A IL 15789302A IL 15789302 A IL15789302 A IL 15789302A IL 157893 A0 IL157893 A0 IL 157893A0
Authority
IL
Israel
Prior art keywords
piperidin
cyclohexyl
amines
phenyl
analgesics
Prior art date
Application number
IL15789302A
Other languages
English (en)
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of IL157893A0 publication Critical patent/IL157893A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL15789302A 2001-03-14 2002-03-13 Substituted dimethyl-[1-(1-phenyl-cyclohexyl)-piperidin-3-yl methyl]-amines and the use of the same as analgesics IL157893A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10112198A DE10112198A1 (de) 2001-03-14 2001-03-14 Substituierte Dimethyl-[1-(1-phenyl-cyclohexyl)-piperidin-3-ylmethyl]-amine
PCT/EP2002/002723 WO2002072550A1 (de) 2001-03-14 2002-03-13 Substituierte dimethyl`1-(1-phenyl-cyclohexyl)-piperidin-3-ylmethyl!-amine und verwendung als analgetika

Publications (1)

Publication Number Publication Date
IL157893A0 true IL157893A0 (en) 2004-03-28

Family

ID=7677392

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15789302A IL157893A0 (en) 2001-03-14 2002-03-13 Substituted dimethyl-[1-(1-phenyl-cyclohexyl)-piperidin-3-yl methyl]-amines and the use of the same as analgesics

Country Status (23)

Country Link
US (1) US7049327B2 (ja)
EP (1) EP1370529B1 (ja)
JP (1) JP2004526726A (ja)
KR (1) KR20040012733A (ja)
CN (1) CN1496352A (ja)
AT (1) ATE315551T1 (ja)
BR (1) BR0208243A (ja)
CA (1) CA2440758A1 (ja)
CZ (1) CZ20032455A3 (ja)
DE (2) DE10112198A1 (ja)
DK (1) DK1370529T3 (ja)
EC (1) ECSP034768A (ja)
ES (1) ES2256499T3 (ja)
HU (1) HUP0302800A2 (ja)
IL (1) IL157893A0 (ja)
MX (1) MXPA03007967A (ja)
NO (1) NO20034029L (ja)
PE (1) PE20020926A1 (ja)
PL (1) PL364415A1 (ja)
RU (1) RU2003129061A (ja)
SK (1) SK11122003A3 (ja)
WO (1) WO2002072550A1 (ja)
ZA (1) ZA200307964B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105646332B (zh) * 2014-11-09 2018-05-25 复旦大学 氨基甲基哌啶类衍生物及其制备方法和药物用途
KR102603671B1 (ko) * 2017-01-17 2023-11-17 메비아스 디스커버리 인코포레이티드 치환된 3-디알킬아미노메틸-피페리딘-4-일-벤즈아미드 및 이를 제조 및 사용하는 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL40064A0 (en) * 1972-08-07 1972-10-29 Univ Tel Aviv Phencyclidine and its derivatives as short-time acting midriatics
WO1998055478A1 (fr) * 1997-06-03 1998-12-10 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Nouveaux derives de phencyclidines, des procedes pour leur preparation et des compositions pharmaceutiques les contenant
US4598153A (en) * 1984-12-19 1986-07-01 The United States Of America As Represented By The Department Of Health And Human Services Metaphit, a specific acylating agent for the [3 H] phencyclidine
US5155212A (en) * 1986-05-21 1992-10-13 Abbott Laboratories Phencyclidine and phencyclidine metabolites assay, tracers, immunogens, antibodies and reagent kit
ATE212981T1 (de) * 1994-09-30 2002-02-15 Novartis Erfind Verwalt Gmbh 1-acyl-4-aliphatische aminopiperidin verbindungen
ID29137A (id) * 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate

Also Published As

Publication number Publication date
JP2004526726A (ja) 2004-09-02
EP1370529B1 (de) 2006-01-11
ECSP034768A (es) 2003-10-28
DE50205593D1 (de) 2006-04-06
CN1496352A (zh) 2004-05-12
ZA200307964B (en) 2004-09-14
EP1370529A1 (de) 2003-12-17
US20040127516A1 (en) 2004-07-01
DE10112198A1 (de) 2002-09-19
KR20040012733A (ko) 2004-02-11
CA2440758A1 (en) 2002-09-19
ES2256499T3 (es) 2006-07-16
SK11122003A3 (sk) 2004-01-08
NO20034029L (no) 2003-11-13
PE20020926A1 (es) 2002-10-26
CZ20032455A3 (cs) 2003-12-17
NO20034029D0 (no) 2003-09-11
DK1370529T3 (da) 2006-05-22
PL364415A1 (en) 2004-12-13
RU2003129061A (ru) 2005-04-10
MXPA03007967A (es) 2004-10-15
ATE315551T1 (de) 2006-02-15
US7049327B2 (en) 2006-05-23
BR0208243A (pt) 2004-03-09
WO2002072550A1 (de) 2002-09-19
HUP0302800A2 (hu) 2003-11-28

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