IL153309A0 - Method to detect modulators of vegf kinase domain - Google Patents

Method to detect modulators of vegf kinase domain

Info

Publication number
IL153309A0
IL153309A0 IL15330901A IL15330901A IL153309A0 IL 153309 A0 IL153309 A0 IL 153309A0 IL 15330901 A IL15330901 A IL 15330901A IL 15330901 A IL15330901 A IL 15330901A IL 153309 A0 IL153309 A0 IL 153309A0
Authority
IL
Israel
Prior art keywords
kinase domain
vegf kinase
modulators
detect modulators
detect
Prior art date
Application number
IL15330901A
Other languages
English (en)
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of IL153309A0 publication Critical patent/IL153309A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL15330901A 2000-06-07 2001-06-06 Method to detect modulators of vegf kinase domain IL153309A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21013200P 2000-06-07 2000-06-07
PCT/US2001/018312 WO2001094624A1 (fr) 2000-06-07 2001-06-06 Methode permettant de detecter des modulateurs du domaine kinase du recepteur du vegf

Publications (1)

Publication Number Publication Date
IL153309A0 true IL153309A0 (en) 2003-07-06

Family

ID=22781690

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15330901A IL153309A0 (en) 2000-06-07 2001-06-06 Method to detect modulators of vegf kinase domain

Country Status (16)

Country Link
US (1) US7070938B2 (fr)
EP (1) EP1294929B1 (fr)
JP (1) JP2004508016A (fr)
CN (1) CN1457366A (fr)
AT (1) ATE307215T1 (fr)
AU (2) AU6821301A (fr)
BR (1) BR0111530A (fr)
CA (1) CA2411072A1 (fr)
DE (1) DE60114196T2 (fr)
DK (1) DK1294929T3 (fr)
ES (1) ES2250420T3 (fr)
IL (1) IL153309A0 (fr)
MX (1) MXPA02012224A (fr)
NZ (1) NZ523386A (fr)
WO (1) WO2001094624A1 (fr)
ZA (1) ZA200300128B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI270545B (en) 2000-05-24 2007-01-11 Sugen Inc Mannich base prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568649A (en) 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
US5185438A (en) 1991-04-02 1993-02-09 The Trustees Of Princeton University Nucleic acids encoding hencatoporetic stem cell receptor flk-2
US5861301A (en) 1992-02-20 1999-01-19 American Cayanamid Company Recombinant kinase insert domain containing receptor and gene encoding same
US5770176A (en) 1995-12-08 1998-06-23 Chiron Diagnostics Corporation Assays for functional nuclear receptors
WO1997034920A1 (fr) * 1996-03-21 1997-09-25 Sugen, Inc. Dosages pour inhibiteurs du recepteur tyrosine kinase kdr/flk-1
US6204011B1 (en) 1997-06-18 2001-03-20 Merck & Co., Inc. Human receptor tyrosine kinase, KDR
US6316603B1 (en) * 1998-09-08 2001-11-13 Agouron Pharmaceuticals, Inc. Modifications of the VEGF receptor-2 protein and methods of use

Also Published As

Publication number Publication date
ZA200300128B (en) 2004-02-13
EP1294929A1 (fr) 2003-03-26
NZ523386A (en) 2004-07-30
DE60114196D1 (de) 2006-03-02
ATE307215T1 (de) 2005-11-15
DE60114196T2 (de) 2006-07-20
EP1294929B1 (fr) 2005-10-19
CA2411072A1 (fr) 2001-12-13
ES2250420T3 (es) 2006-04-16
DK1294929T3 (da) 2005-12-12
CN1457366A (zh) 2003-11-19
US20020037537A1 (en) 2002-03-28
WO2001094624A1 (fr) 2001-12-13
AU2001268213B2 (en) 2005-11-10
JP2004508016A (ja) 2004-03-18
AU6821301A (en) 2001-12-17
BR0111530A (pt) 2003-07-22
EP1294929A4 (fr) 2004-12-29
US7070938B2 (en) 2006-07-04
MXPA02012224A (es) 2004-08-19

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