IL152625A0 - SYNTHETIC IMMUNOGENIC BUT NON-AMYLOIDOGENIC PEPTIDES HOMOLOGOUS TO AMYLOID beta FOR INDUCTION OF AN IMMUNE RESPONSE TO AMYLOID beta AND AMYLOID DEPOSITS - Google Patents
SYNTHETIC IMMUNOGENIC BUT NON-AMYLOIDOGENIC PEPTIDES HOMOLOGOUS TO AMYLOID beta FOR INDUCTION OF AN IMMUNE RESPONSE TO AMYLOID beta AND AMYLOID DEPOSITSInfo
- Publication number
- IL152625A0 IL152625A0 IL15262501A IL15262501A IL152625A0 IL 152625 A0 IL152625 A0 IL 152625A0 IL 15262501 A IL15262501 A IL 15262501A IL 15262501 A IL15262501 A IL 15262501A IL 152625 A0 IL152625 A0 IL 152625A0
- Authority
- IL
- Israel
- Prior art keywords
- amyloid
- amyloid beta
- immune response
- induction
- deposits
- Prior art date
Links
- 102000013455 Amyloid beta-Peptides Human genes 0.000 title abstract 4
- 108010090849 Amyloid beta-Peptides Proteins 0.000 title abstract 4
- 208000037259 Amyloid Plaque Diseases 0.000 title abstract 2
- 230000028993 immune response Effects 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000006698 induction Effects 0.000 title 1
- 102000009091 Amyloidogenic Proteins Human genes 0.000 abstract 1
- 108010048112 Amyloidogenic Proteins Proteins 0.000 abstract 1
- 230000003942 amyloidogenic effect Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20557800P | 2000-05-22 | 2000-05-22 | |
PCT/US2001/016322 WO2001090182A2 (en) | 2000-05-22 | 2001-05-22 | Synthetic immunogenic but non-amyloidogenic peptides homologous to amyloid beta for induction of an immune response to amyloid beta and amyloid deposits |
Publications (1)
Publication Number | Publication Date |
---|---|
IL152625A0 true IL152625A0 (en) | 2003-06-24 |
Family
ID=22762767
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15262501A IL152625A0 (en) | 2000-05-22 | 2001-05-22 | SYNTHETIC IMMUNOGENIC BUT NON-AMYLOIDOGENIC PEPTIDES HOMOLOGOUS TO AMYLOID beta FOR INDUCTION OF AN IMMUNE RESPONSE TO AMYLOID beta AND AMYLOID DEPOSITS |
IL152625A IL152625A (en) | 2000-05-22 | 2002-11-03 | Synthetic but not amyloidogenic immunogenic peptides equivalent to amyloid b to elicit an immune response to amyloid b and amyloid deposits |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL152625A IL152625A (en) | 2000-05-22 | 2002-11-03 | Synthetic but not amyloidogenic immunogenic peptides equivalent to amyloid b to elicit an immune response to amyloid b and amyloid deposits |
Country Status (14)
Country | Link |
---|---|
US (3) | US6713450B2 (es) |
EP (1) | EP1284998B1 (es) |
JP (1) | JP2003534351A (es) |
CN (1) | CN1249085C (es) |
AT (1) | ATE286072T1 (es) |
AU (2) | AU2001274873B2 (es) |
CA (1) | CA2408925A1 (es) |
DE (1) | DE60108111T2 (es) |
ES (1) | ES2238049T3 (es) |
IL (2) | IL152625A0 (es) |
NZ (1) | NZ521939A (es) |
PT (1) | PT1284998E (es) |
WO (1) | WO2001090182A2 (es) |
ZA (1) | ZA200207992B (es) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6787523B1 (en) | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US7179892B2 (en) * | 2000-12-06 | 2007-02-20 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
US6750324B1 (en) | 1997-12-02 | 2004-06-15 | Neuralab Limited | Humanized and chimeric N-terminal amyloid beta-antibodies |
US6913745B1 (en) | 1997-12-02 | 2005-07-05 | Neuralab Limited | Passive immunization of Alzheimer's disease |
US6905686B1 (en) * | 1997-12-02 | 2005-06-14 | Neuralab Limited | Active immunization for treatment of alzheimer's disease |
US20080050367A1 (en) * | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US6761888B1 (en) * | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US6923964B1 (en) | 1997-12-02 | 2005-08-02 | Neuralab Limited | Active immunization of AScr for prion disorders |
US7790856B2 (en) * | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
US20030147882A1 (en) * | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
US7148324B1 (en) * | 1998-12-14 | 2006-12-12 | Dendreon Corporation | Compositions and methods for enhancement of major histocompatibility complex class I restricted antigen presentation |
US6787637B1 (en) | 1999-05-28 | 2004-09-07 | Neuralab Limited | N-Terminal amyloid-β antibodies |
UA81216C2 (en) * | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
JP5025871B2 (ja) * | 2000-02-21 | 2012-09-12 | エイチ.リュンドベック エイ/エス | アミロイドの新規なダウン−レギュレート方法 |
CA2400838C (en) * | 2000-02-21 | 2013-04-23 | Pharmexa A/S | Novel method for down-regulation of amyloid |
EP1309341A2 (en) | 2000-07-07 | 2003-05-14 | Lars Lannfelt | Prevention and treatment of alzheimer's disease |
PE20020574A1 (es) * | 2000-12-06 | 2002-07-02 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido amiloideo beta |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
US20040191264A1 (en) * | 2001-02-19 | 2004-09-30 | Nielsen Klaus Gregorius | Synthetic vaccine agents |
US7097837B2 (en) * | 2001-02-19 | 2006-08-29 | Pharmexa A/S | Synthetic vaccine agents |
US6815175B2 (en) | 2001-03-16 | 2004-11-09 | Cornell Research Foundation, Inc. | Anti-amyloid peptide antibody based diagnosis and treatment of a neurological disease or disorder |
US20030130484A1 (en) * | 2001-03-20 | 2003-07-10 | Gordon David J. | Inhibitors and disassemblers of fibrillogenesis |
MY144532A (en) * | 2001-08-20 | 2011-09-30 | Lundbeck & Co As H | Novel method for down-regulation of amyloid |
CA2466841A1 (en) * | 2001-11-21 | 2003-06-05 | New York University | Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid .beta., prion protein, amylin, .alpha.-synuclein, or polyglutamine repeats for induction of an immune response thereto |
MY139983A (en) * | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
EP1575529A4 (en) * | 2002-07-17 | 2007-08-08 | Intellect Neurosciences Inc | PEPTIDES AND METHOD FOR THE INVESTIGATION OF IMMUNOGENOUS PEPTIDE VACCINES AGAINST ALZHEIMER DISEASE |
EP1560850A2 (en) * | 2002-11-14 | 2005-08-10 | Adherex Technologies, Inc. | Compounds and methods for modulating desmosomal and atypical cadherin-mediated cell adhesion |
US20070010435A1 (en) | 2002-12-19 | 2007-01-11 | New York University | Method for treating amyloid disease |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
GB0310270D0 (en) * | 2003-05-03 | 2003-06-11 | Univ Edinburgh | Biomolecular devices |
PE20050627A1 (es) | 2003-05-30 | 2005-08-10 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
EA009559B1 (ru) | 2003-12-17 | 2008-02-28 | Элан Фармасьютикелз, Инк. | КОНЪЮГАТЫ Aβ ИММУНОГЕННЫХ ПЕПТИДНЫХ НОСИТЕЛЕЙ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ |
SE0401601D0 (sv) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
KR20070100234A (ko) * | 2004-10-06 | 2007-10-10 | 히로시 모리 | 변이형 아밀로이드 단백질 |
CA2590337C (en) | 2004-12-15 | 2017-07-11 | Neuralab Limited | Humanized amyloid beta antibodies for use in improving cognition |
EP1838349A1 (en) * | 2004-12-15 | 2007-10-03 | Neuralab, Ltd. | Amyloid beta antibodies for use in improving cognition |
WO2006066049A2 (en) * | 2004-12-15 | 2006-06-22 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
CA2912012C (en) | 2005-05-05 | 2018-05-29 | Sensient Flavors Inc. | Production of beta-glucans and mannans |
KR20080090408A (ko) * | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
KR101439828B1 (ko) * | 2005-11-30 | 2014-09-17 | 애브비 인코포레이티드 | 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도 |
JP5033868B2 (ja) | 2006-03-23 | 2012-09-26 | バイオアークティック ニューロサイエンス アーベー | 改良型プロトフィブリル選択的抗体及びその使用 |
US8784810B2 (en) * | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
US20090123488A1 (en) * | 2006-08-14 | 2009-05-14 | Thymon, Llc | Compositions and methods for the treatment and prophylaxis of Alzheimer's disease |
CA2660830A1 (en) * | 2006-08-14 | 2008-02-21 | Gideon Goldstein | Compositions and methods for the treatment and prophylaxis of multiple strains and subtypes of hiv-1 |
WO2008070284A2 (en) | 2006-10-16 | 2008-06-12 | Johnnie B. Byrd, Sr. Alzheimer's Center And Research Institute | Amyloid beta peptides and methods of uses thereof |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
WO2008099917A1 (ja) * | 2007-02-15 | 2008-08-21 | Fukuoka University | 抗hmgb-1抗体を含む臓器移植拒絶抑制剤 |
EP2123299A4 (en) * | 2007-02-15 | 2011-10-05 | Univ Kyushu Nat Univ Corp | THERAPEUTIC AGENT FOR INTERSTITIAL PULMONARY DISEASE COMPRISING ANTI-HMGB-1 ANTIBODY |
EP2123297A4 (en) | 2007-02-15 | 2011-10-12 | Univ Kumamoto | THERAPEUTIC AGENT COMPRISING AN ANTIBODY CAPABLE OF BINDING SPECIFICALLY TO HMGB-1 AS ACTIVE INGREDIENT |
US8895004B2 (en) | 2007-02-27 | 2014-11-25 | AbbVie Deutschland GmbH & Co. KG | Method for the treatment of amyloidoses |
US7618944B2 (en) * | 2007-03-01 | 2009-11-17 | Intezyne Technologies, Inc. | Encapsulated amyloid-beta peptides |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
MX2009011127A (es) * | 2007-04-18 | 2010-03-10 | Janssen Alzheimer Immunotherap | Metodo de prevencion y tratamiento de angiopatia amiloide cerebral. |
SI2182983T1 (sl) | 2007-07-27 | 2014-09-30 | Janssen Alzheimer Immunotherapy | Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta |
JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
KR101478995B1 (ko) | 2007-11-16 | 2015-01-12 | 더 락커펠러 유니버시티 | 원섬유 형태의 베타아밀로이드 단백질에 대해 특이적인 항체 |
NZ590324A (en) * | 2008-07-01 | 2012-08-31 | Nederlanden Staat | Vaccine against amyloid folding intermediate |
US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
TWI508976B (zh) * | 2009-04-21 | 2015-11-21 | Univ Rockefeller | 對β-類澱粉蛋白之基原纖維形式具專一性之抗體 |
US8409584B2 (en) | 2009-05-05 | 2013-04-02 | New York University | Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins |
EP2440234A4 (en) * | 2009-06-10 | 2013-11-06 | Univ New York | IMMUNOLOGICAL TARGETING OF PATHOLOGICAL TAU PROTEINS |
CN101920008B (zh) * | 2009-06-15 | 2013-07-31 | 浙江仙琚制药股份有限公司 | 包含Aβ40多肽和铝佐剂的制剂以及纯化Aβ40多肽的方法 |
WO2011130377A2 (en) | 2010-04-15 | 2011-10-20 | Abbott Laboratories | Amyloid-beta binding proteins |
CN103298833B (zh) | 2010-08-14 | 2015-12-16 | Abbvie公司 | β淀粉样蛋白结合蛋白 |
US9926353B2 (en) | 2011-07-19 | 2018-03-27 | New York University | Immunotherapeutic modulation of amyloidogenic disease using non-fibrillogenic, non-amyloidogenic polymerized proteins and peptides |
US8906382B2 (en) | 2011-07-19 | 2014-12-09 | New York University | Method for treating amyloid disease |
KR102564384B1 (ko) | 2014-07-10 | 2023-08-07 | 바이오악틱 에이비 | 개선된 Aβ 프로토피브릴 결합 항체 |
US11970521B2 (en) * | 2016-08-20 | 2024-04-30 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Neuroprotective beta amyloid core peptides and peptidomimetic derivatives |
WO2023161526A1 (en) | 2022-02-28 | 2023-08-31 | Tridem Bioscience Gmbh & Co Kg | A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN |
WO2023161527A1 (en) | 2022-02-28 | 2023-08-31 | Tridem Bioscience Gmbh & Co Kg | A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE202940T1 (de) | 1994-05-25 | 2001-07-15 | John Mcmichael | Mittel und methoden zur behandlung von plaque- krankheiten |
US5688651A (en) * | 1994-12-16 | 1997-11-18 | Ramot University Authority For Applied Research And Development Ltd. | Prevention of protein aggregation |
US5948763A (en) * | 1995-06-07 | 1999-09-07 | New York University | Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits |
US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US6787523B1 (en) * | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
EP1033998B1 (en) | 1997-12-03 | 2005-10-19 | Neuralab, Ltd. | Suppressing beta-amyloid-related changes in alzheimer's disease |
-
2001
- 2001-05-22 DE DE60108111T patent/DE60108111T2/de not_active Expired - Lifetime
- 2001-05-22 AU AU2001274873A patent/AU2001274873B2/en not_active Ceased
- 2001-05-22 AU AU7487301A patent/AU7487301A/xx active Pending
- 2001-05-22 ES ES01941526T patent/ES2238049T3/es not_active Expired - Lifetime
- 2001-05-22 AT AT01941526T patent/ATE286072T1/de not_active IP Right Cessation
- 2001-05-22 CN CNB018100058A patent/CN1249085C/zh not_active Expired - Fee Related
- 2001-05-22 JP JP2001586993A patent/JP2003534351A/ja not_active Withdrawn
- 2001-05-22 EP EP01941526A patent/EP1284998B1/en not_active Expired - Lifetime
- 2001-05-22 WO PCT/US2001/016322 patent/WO2001090182A2/en active IP Right Grant
- 2001-05-22 PT PT01941526T patent/PT1284998E/pt unknown
- 2001-05-22 CA CA002408925A patent/CA2408925A1/en not_active Abandoned
- 2001-05-22 US US09/861,847 patent/US6713450B2/en not_active Expired - Lifetime
- 2001-05-22 NZ NZ521939A patent/NZ521939A/en unknown
- 2001-05-22 IL IL15262501A patent/IL152625A0/xx unknown
-
2002
- 2002-10-04 ZA ZA200207992A patent/ZA200207992B/xx unknown
- 2002-11-03 IL IL152625A patent/IL152625A/en not_active IP Right Cessation
-
2003
- 2003-09-19 US US10/666,423 patent/US7427655B2/en not_active Expired - Fee Related
-
2008
- 2008-09-19 US US12/234,456 patent/US7700107B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PT1284998E (pt) | 2005-06-30 |
ES2238049T3 (es) | 2005-08-16 |
CN1444598A (zh) | 2003-09-24 |
WO2001090182A3 (en) | 2002-05-23 |
IL152625A (en) | 2009-12-24 |
US20020077288A1 (en) | 2002-06-20 |
CN1249085C (zh) | 2006-04-05 |
WO2001090182A2 (en) | 2001-11-29 |
ZA200207992B (en) | 2003-07-02 |
US6713450B2 (en) | 2004-03-30 |
DE60108111T2 (de) | 2005-12-08 |
US20040043935A1 (en) | 2004-03-04 |
EP1284998A2 (en) | 2003-02-26 |
US7427655B2 (en) | 2008-09-23 |
NZ521939A (en) | 2004-04-30 |
US7700107B2 (en) | 2010-04-20 |
AU7487301A (en) | 2001-12-03 |
US20090081204A1 (en) | 2009-03-26 |
ATE286072T1 (de) | 2005-01-15 |
JP2003534351A (ja) | 2003-11-18 |
AU2001274873B2 (en) | 2006-10-05 |
DE60108111D1 (de) | 2005-02-03 |
CA2408925A1 (en) | 2001-11-29 |
EP1284998B1 (en) | 2004-12-29 |
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