IL147657A0 - Corticotropin releasing factor receptor 2 deficient mice and uses thereof - Google Patents

Corticotropin releasing factor receptor 2 deficient mice and uses thereof

Info

Publication number
IL147657A0
IL147657A0 IL14765700A IL14765700A IL147657A0 IL 147657 A0 IL147657 A0 IL 147657A0 IL 14765700 A IL14765700 A IL 14765700A IL 14765700 A IL14765700 A IL 14765700A IL 147657 A0 IL147657 A0 IL 147657A0
Authority
IL
Israel
Prior art keywords
factor receptor
deficient mice
releasing factor
corticotropin releasing
corticotropin
Prior art date
Application number
IL14765700A
Other languages
English (en)
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of IL147657A0 publication Critical patent/IL147657A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0356—Animal model for processes and diseases of the central nervous system, e.g. stress, learning, schizophrenia, pain, epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14765700A 1999-07-15 2000-07-14 Corticotropin releasing factor receptor 2 deficient mice and uses thereof IL147657A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14426199P 1999-07-15 1999-07-15
PCT/US2000/019371 WO2001005222A1 (en) 1999-07-15 2000-07-14 Corticotropin releasing factor receptor 2 deficient mice and uses thereof

Publications (1)

Publication Number Publication Date
IL147657A0 true IL147657A0 (en) 2002-08-14

Family

ID=22507801

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14765700A IL147657A0 (en) 1999-07-15 2000-07-14 Corticotropin releasing factor receptor 2 deficient mice and uses thereof

Country Status (11)

Country Link
US (1) US6353152B1 (xx)
EP (1) EP1196027A4 (xx)
KR (1) KR20020092891A (xx)
CN (1) CN1188031C (xx)
AU (1) AU780829B2 (xx)
CA (1) CA2375943A1 (xx)
IL (1) IL147657A0 (xx)
NZ (1) NZ516611A (xx)
RU (1) RU2251838C2 (xx)
WO (1) WO2001005222A1 (xx)
ZA (1) ZA200200294B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040034882A1 (en) * 1999-07-15 2004-02-19 Vale Wylie W. Corticotropin releasing factor receptor 2 deficient mice and uses thereof
US7674463B1 (en) * 1999-07-15 2010-03-09 Research Development Foundation Method of inhibiting angiogenesis by administration of a corticotropin releasing factor receptor 2 agonist
NZ524477A (en) 2001-03-15 2004-11-26 Res Dev Foundation Urocortin-III and uses thereof
US20030194734A1 (en) * 2002-03-29 2003-10-16 Tim Jatkoe Selection of markers
US7348142B2 (en) * 2002-03-29 2008-03-25 Veridex, Lcc Cancer diagnostic panel
US20030186302A1 (en) * 2002-03-29 2003-10-02 Yixin Wang Colorectal cancer diagnostics
US7473526B2 (en) * 2002-03-29 2009-01-06 Veridex, Llc Breast cancer prognostic portfolio
US7488865B2 (en) * 2002-05-20 2009-02-10 Research Development Foundation Urocortin-deficient mice and uses thereof
EP1567869B1 (en) * 2002-11-28 2007-08-22 Neurosearch A/S Method for screening for compounds as potential sedatives or anxiolytics
US6923933B2 (en) * 2003-03-21 2005-08-02 Graham Engineering Corp. Take-out device for rotary blow molding machine and method
US20050042212A1 (en) * 2003-07-24 2005-02-24 Nanda Steven A. Method of reducing CRF receptor mRNA
DE602006012811D1 (de) * 2005-01-28 2010-04-22 Astellas Pharma Inc Verfahren zum screening eines therapeutischen wirkstoffs für darmirritationssyndrome
EE200600039A (et) * 2006-12-12 2008-10-15 Tartu Ülikool Transgeenne loommudel patoloogilise ärevuse modelleerimiseks, meetod patoloogilisest ärevusest p?hjustatud haiguste v?i seisundite ravimiseks sobilike ühendite tuvastamiseks ja meetod Wfs1 valgu kasutamiseks sihtmärgina patoloogilise ärevuse vastase
EP2522351B1 (en) 2007-06-13 2017-09-06 Research Development Foundation Treatment and prevention of tauopathies and amyloid beta amyloidosis by modulating CRF receptor signaling
WO2011025905A1 (en) 2009-08-28 2011-03-03 Research Development Foundation Urocortin 2 analogs and uses thereof
JP6396883B2 (ja) * 2012-03-20 2018-09-26 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー うつ病の非ヒト動物モデルおよびその使用方法
ES2561728B1 (es) 2014-08-29 2017-01-18 Consejo Superior De Investigaciones Científicas (Csic) Modelo animal no humano para transtornos del espectro autista, ansiedad y/o depresion
CN117143236A (zh) * 2023-08-31 2023-12-01 美康生物科技股份有限公司 一种抗acth抗体及其制备方法、检测试剂盒

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034651A2 (en) * 1994-06-14 1995-12-21 Neurocrine Biosciences, Inc. Corticotropin-releasing factor2 receptors

Also Published As

Publication number Publication date
AU780829B2 (en) 2005-04-21
CN1371243A (zh) 2002-09-25
RU2251838C2 (ru) 2005-05-20
KR20020092891A (ko) 2002-12-12
US6353152B1 (en) 2002-03-05
EP1196027A1 (en) 2002-04-17
AU6216700A (en) 2001-02-05
CA2375943A1 (en) 2001-01-25
EP1196027A4 (en) 2004-12-22
NZ516611A (en) 2003-09-26
RU2002103717A (ru) 2004-03-10
CN1188031C (zh) 2005-02-09
ZA200200294B (en) 2003-04-30
WO2001005222A1 (en) 2001-01-25

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