IL147412A0 - The use of il6r/il6 chimera in nerve cell regeneration - Google Patents

The use of il6r/il6 chimera in nerve cell regeneration

Info

Publication number
IL147412A0
IL147412A0 IL14741201A IL14741201A IL147412A0 IL 147412 A0 IL147412 A0 IL 147412A0 IL 14741201 A IL14741201 A IL 14741201A IL 14741201 A IL14741201 A IL 14741201A IL 147412 A0 IL147412 A0 IL 147412A0
Authority
IL
Israel
Prior art keywords
il6r
chimera
nerve cell
cell regeneration
regeneration
Prior art date
Application number
IL14741201A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL14741201A priority Critical patent/IL147412A0/xx
Publication of IL147412A0 publication Critical patent/IL147412A0/xx
Priority to EP02796952.6A priority patent/EP1461066B1/en
Priority to CA2472203A priority patent/CA2472203C/en
Priority to US10/498,899 priority patent/US7824670B2/en
Priority to IL16248202A priority patent/IL162482A0/xx
Priority to ES02796952.6T priority patent/ES2535156T3/es
Priority to JP2003559537A priority patent/JP4685354B2/ja
Priority to PCT/IL2002/001058 priority patent/WO2003059376A1/en
Priority to AU2002361489A priority patent/AU2002361489B2/en
Priority to IL162482A priority patent/IL162482A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL14741201A 2001-12-31 2001-12-31 The use of il6r/il6 chimera in nerve cell regeneration IL147412A0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IL14741201A IL147412A0 (en) 2001-12-31 2001-12-31 The use of il6r/il6 chimera in nerve cell regeneration
EP02796952.6A EP1461066B1 (en) 2001-12-31 2002-12-31 The use of il6r/il6 chimera in nerve cell regeneration
CA2472203A CA2472203C (en) 2001-12-31 2002-12-31 The use of il6r/il6 chimera in nerve cell regeneration
US10/498,899 US7824670B2 (en) 2001-12-31 2002-12-31 Use of il6r/il6 chimera in nerve cell regeneration
IL16248202A IL162482A0 (en) 2001-12-31 2002-12-31 Use of il6r/il/6 chimera in the manufacture of a medicament
ES02796952.6T ES2535156T3 (es) 2001-12-31 2002-12-31 Uso de quimera IL6R/IL6 en la regeneración de células nerviosas
JP2003559537A JP4685354B2 (ja) 2001-12-31 2002-12-31 神経細胞の再生におけるｉｌ６ｒ／ｉｌ６キメラの使用
PCT/IL2002/001058 WO2003059376A1 (en) 2001-12-31 2002-12-31 The use of il6r/il6 chimera in nerve cell regeneration
AU2002361489A AU2002361489B2 (en) 2001-12-31 2002-12-31 The use of IL6R/IL6 chimera in nerve cell regeneration
IL162482A IL162482A (en) 2001-12-31 2004-06-13 Use of the il6 – r / il – 6 chimera in the manufacture of a drug for the treatment of neuronal loss

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL14741201A IL147412A0 (en) 2001-12-31 2001-12-31 The use of il6r/il6 chimera in nerve cell regeneration

Publications (1)

Publication Number Publication Date
IL147412A0 true IL147412A0 (en) 2002-08-14

Family

ID=11075915

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14741201A IL147412A0 (en) 2001-12-31 2001-12-31 The use of il6r/il6 chimera in nerve cell regeneration
IL162482A IL162482A (en) 2001-12-31 2004-06-13 Use of the il6 – r / il – 6 chimera in the manufacture of a drug for the treatment of neuronal loss

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL162482A IL162482A (en) 2001-12-31 2004-06-13 Use of the il6 – r / il – 6 chimera in the manufacture of a drug for the treatment of neuronal loss

Country Status (8)

Country Link
US (1) US7824670B2 (xx)
EP (1) EP1461066B1 (xx)
JP (1) JP4685354B2 (xx)
AU (1) AU2002361489B2 (xx)
CA (1) CA2472203C (xx)
ES (1) ES2535156T3 (xx)
IL (2) IL147412A0 (xx)
WO (1) WO2003059376A1 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004111210A1 (en) * 2003-06-12 2004-12-23 Yeda Research & Development Co.Ltd Enhancement of oligodendrocyte differentiation
IL157309A0 (en) 2003-08-07 2004-02-19 Applied Research Systems Method for the purification of a non-immunoglobulin protein
EP1784486B1 (en) * 2004-06-23 2011-10-05 TissueGene, Inc. Nerve regeneration
EP1962719A4 (en) * 2005-08-29 2011-05-04 Technion Res And Dev Of Foundation Ltd MEDIA FOR BREEDING STEM CELLS
GB0815216D0 (en) * 2008-08-21 2008-09-24 Asterion Ltd Interleukin
AU2010223268B2 (en) * 2009-03-12 2015-04-23 Haase Investments Gmbh Bone morphogenetic protein 2 (BMP2 ) variants with reduced BMP antagonist sensitivity
US20120219535A1 (en) * 2009-10-02 2012-08-30 University Of Southern California Cranial neural crest stem cells and culture condition that supports their growth
US20130143805A1 (en) * 2010-08-13 2013-06-06 Georgetown University Ggf2 and methods of use
DK2859015T3 (en) 2012-06-08 2018-06-18 Alkermes Inc LIGANDS MODIFIED BY CIRCULAR MODIFICATION AS AGONISTS AND ANTAGONISTS
WO2020006469A1 (en) * 2018-06-29 2020-01-02 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for treating and reducing traumatic brain injury-associated impairments using sgp130
IL299911A (en) * 2020-08-14 2023-03-01 Kite Pharma Inc Improving immune cell function

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0987198A (ja) 1995-09-19 1997-03-31 Tosoh Corp 神経細胞伸長剤
IL122818A0 (en) 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
IL130586A0 (en) * 1999-06-21 2000-06-01 Yeda Res & Dev IL6RIL6 chimera for the treatment of demyelinating diseases
US6749850B1 (en) * 1999-08-18 2004-06-15 The General Hospital Corporation Methods, compositions and kits for promoting recovery from damage to the central nervous system
WO2001076507A2 (en) * 2000-04-11 2001-10-18 The University Of Miami Use of oxygen carriers to improve grafted cell survival in neural transplantation
DE60119347T2 (de) 2000-09-14 2007-02-22 Ares Trading S.A. Verwendung von chimäres il6-il6r in huntingtonskrankheit

Also Published As

Publication number Publication date
JP4685354B2 (ja) 2011-05-18
CA2472203C (en) 2014-02-18
EP1461066A1 (en) 2004-09-29
EP1461066B1 (en) 2015-02-25
WO2003059376A8 (en) 2003-10-09
US20050220761A1 (en) 2005-10-06
WO2003059376A1 (en) 2003-07-24
AU2002361489B2 (en) 2008-05-08
IL162482A (en) 2013-06-27
JP2005514442A (ja) 2005-05-19
AU2002361489A1 (en) 2003-07-30
ES2535156T3 (es) 2015-05-05
CA2472203A1 (en) 2003-07-24
US7824670B2 (en) 2010-11-02

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