IL147286A0 - Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates - Google Patents

Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates

Info

Publication number
IL147286A0
IL147286A0 IL14728600A IL14728600A IL147286A0 IL 147286 A0 IL147286 A0 IL 147286A0 IL 14728600 A IL14728600 A IL 14728600A IL 14728600 A IL14728600 A IL 14728600A IL 147286 A0 IL147286 A0 IL 147286A0
Authority
IL
Israel
Prior art keywords
photoreactive
synthesis
phosphoramidite reagents
solid phase
phase synthesis
Prior art date
Application number
IL14728600A
Other languages
English (en)
Original Assignee
Exiqon As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exiqon As filed Critical Exiqon As
Publication of IL147286A0 publication Critical patent/IL147286A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2408—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyalkyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL14728600A 1999-07-07 2000-07-07 Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates IL147286A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199900987 1999-07-07
PCT/DK2000/000375 WO2001004129A1 (en) 1999-07-07 2000-07-07 Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates

Publications (1)

Publication Number Publication Date
IL147286A0 true IL147286A0 (en) 2002-08-14

Family

ID=8099743

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14728600A IL147286A0 (en) 1999-07-07 2000-07-07 Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates

Country Status (8)

Country Link
EP (1) EP1202998B1 (ja)
JP (1) JP2003504375A (ja)
AT (1) ATE254624T1 (ja)
AU (1) AU5805900A (ja)
CA (1) CA2377589A1 (ja)
DE (1) DE60006680T2 (ja)
IL (1) IL147286A0 (ja)
WO (1) WO2001004129A1 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1404873B1 (en) * 2001-06-21 2013-05-22 Dynavax Technologies Corporation Chimeric immunomodulatory compounds and methods of using the same
EP2177902B1 (en) * 2002-06-07 2011-09-21 Picosep A/S Method and system for multi-stage isoelectric focussing
JP4694201B2 (ja) * 2002-09-20 2011-06-08 インテグレイテッド ディーエヌエイ テクノロジーズ インコーポレイテッド アントラキノン消光色素、それらの製造方法及び使用
DE10323685A1 (de) * 2003-05-22 2004-12-09 Rühe, Jürgen, Prof. Dr. Verfahren zur kovalenten Immobilisierung von Sonden-Biomolekülen an organischen Oberflächen
US7439341B2 (en) 2003-11-14 2008-10-21 Integrated Dna Technologies, Inc. Fluorescence quenching azo dyes, their methods of preparation and use
EP1809647A4 (en) * 2004-10-25 2010-08-04 Operon Holdings Inc BUILDING BLOCK OF AMINO OR THIOL BINDERS FOR THE SYNTHESIS OF FUNCTIONALIZED AMINO OR THIOL NUCLEIC ACIDS AND METHOD FOR OBTAINING AND USING SAME
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
JP5886828B2 (ja) 2010-03-26 2016-03-16 インテグレイテッド ディーエヌエイ テクノロジーズ インコーポレイテッド 核酸のハイブリダイゼーションを強化する方法
WO2012033848A1 (en) 2010-09-07 2012-03-15 Integrated Dna Technologies, Inc. Modifications for antisense compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4997928A (en) * 1988-09-15 1991-03-05 E. I. Du Pont De Nemours And Company Fluorescent reagents for the preparation of 5'-tagged oligonucleotides
WO1990012802A1 (en) * 1989-04-18 1990-11-01 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof
US5292873A (en) * 1989-11-29 1994-03-08 The Research Foundation Of State University Of New York Nucleic acids labeled with naphthoquinone probe
US5650399A (en) * 1993-08-23 1997-07-22 The Research Foundation Of State University Of New York Reactive anthraquinone derivatives and conjugates thereof
US6506895B2 (en) * 1997-08-15 2003-01-14 Surmodics, Inc. Photoactivatable nucleic acids

Also Published As

Publication number Publication date
JP2003504375A (ja) 2003-02-04
CA2377589A1 (en) 2001-01-18
AU5805900A (en) 2001-01-30
DE60006680T2 (de) 2004-09-16
EP1202998A1 (en) 2002-05-08
WO2001004129A1 (en) 2001-01-18
EP1202998B1 (en) 2003-11-19
DE60006680D1 (de) 2003-12-24
ATE254624T1 (de) 2003-12-15

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