EP1306366A3 - New dibenzosuberone derivatives - Google Patents

New dibenzosuberone derivatives Download PDF

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Publication number
EP1306366A3
EP1306366A3 EP03002060A EP03002060A EP1306366A3 EP 1306366 A3 EP1306366 A3 EP 1306366A3 EP 03002060 A EP03002060 A EP 03002060A EP 03002060 A EP03002060 A EP 03002060A EP 1306366 A3 EP1306366 A3 EP 1306366A3
Authority
EP
European Patent Office
Prior art keywords
new
dibenzosuberone
derivatives
dibenzosuberone derivatives
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03002060A
Other languages
German (de)
French (fr)
Other versions
EP1306366A2 (en
Inventor
Zvonimira Mikotic-Mihun, Ph. D.
Grace Karminski Zamola
Ivica Cepanec, Ph. D.
Mladen M. S. Litvic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Belupo - Lijekovi I Kozmetika d o o
Original Assignee
Belupo - Lijekovi I Kozmetika d o o
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Belupo - Lijekovi I Kozmetika d o o filed Critical Belupo - Lijekovi I Kozmetika d o o
Publication of EP1306366A2 publication Critical patent/EP1306366A2/en
Publication of EP1306366A3 publication Critical patent/EP1306366A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/34—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic
    • C07C65/36—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/52—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of six-membered aromatic rings being part of condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
    • C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes

Abstract

The invention referres to the new dibenzosuberone derivatives N,N'-bis(3'-dimethylamino-1'-propyl)dibenzosuberone-3,7-bis-carboxamide (1) and to the process for its preparation via 3,7-di-cyano-dibenzosuberone (3).
EP03002060A 1997-12-01 1998-11-26 New dibenzosuberone derivatives Withdrawn EP1306366A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HR970649 1997-12-01
HR970649 HRP970649B1 (en) 1997-12-01 1997-12-01 Dibenzosuberone derivatives and processes for their preparation
EP98957044A EP1042268B1 (en) 1997-12-01 1998-11-26 1,7-dibromodibenzosuberone and procedures for its preparation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP98957044A Division EP1042268B1 (en) 1997-12-01 1998-11-26 1,7-dibromodibenzosuberone and procedures for its preparation

Publications (2)

Publication Number Publication Date
EP1306366A2 EP1306366A2 (en) 2003-05-02
EP1306366A3 true EP1306366A3 (en) 2003-05-21

Family

ID=10946663

Family Applications (2)

Application Number Title Priority Date Filing Date
EP98957044A Expired - Lifetime EP1042268B1 (en) 1997-12-01 1998-11-26 1,7-dibromodibenzosuberone and procedures for its preparation
EP03002060A Withdrawn EP1306366A3 (en) 1997-12-01 1998-11-26 New dibenzosuberone derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP98957044A Expired - Lifetime EP1042268B1 (en) 1997-12-01 1998-11-26 1,7-dibromodibenzosuberone and procedures for its preparation

Country Status (5)

Country Link
EP (2) EP1042268B1 (en)
DE (1) DE69814462T2 (en)
ES (1) ES2198771T3 (en)
HR (1) HRP970649B1 (en)
WO (1) WO1999028284A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006306499A1 (en) * 2005-10-21 2007-05-03 Merck Sharp & Dohme Corp. Tyrosine kinase inhibitors
WO2016033722A1 (en) * 2014-09-01 2016-03-10 Therm-O-Disc, Incorporated High thermal stability thermal cutoff device pellet composition
CN116332828A (en) * 2021-12-10 2023-06-27 四川大学 Dibenzocycloheptanone derivatives and application thereof in OLED (organic light emitting diode) device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH541545A (en) * 1970-10-09 1973-09-15 Hoffmann La Roche Process for the preparation of tricyclic imines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DUNN J P ET AL: "Dibenzotropone- and dibenzosuberonecarboxylic acids with bronchodilator activity", J. MED. CHEM. (JMCMAR,00222623);1979; VOL.22 (11); PP.1357-63, Inst. Org. Chem.;Palo Alto; 94304; CA; USA, XP002096404 *
HOLM T: "Preparation and properties of 1,1-diaryl-1,3-butadienes", ACTA CHEMICA SCANDINAVICA., vol. 17, 1963, COPENHAGEN DK, pages 2437 - 2442, XP002096402 *

Also Published As

Publication number Publication date
EP1306366A2 (en) 2003-05-02
EP1042268B1 (en) 2003-05-07
WO1999028284A1 (en) 1999-06-10
HRP970649A2 (en) 2000-02-29
EP1042268A1 (en) 2000-10-11
DE69814462D1 (en) 2003-06-12
HRP970649B1 (en) 2004-12-31
ES2198771T3 (en) 2004-02-01
DE69814462T2 (en) 2004-03-18

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