IL144012A - Method for the preparation of aryl ethers - Google Patents
Method for the preparation of aryl ethersInfo
- Publication number
- IL144012A IL144012A IL14401299A IL14401299A IL144012A IL 144012 A IL144012 A IL 144012A IL 14401299 A IL14401299 A IL 14401299A IL 14401299 A IL14401299 A IL 14401299A IL 144012 A IL144012 A IL 144012A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- aryl ethers
- ethers
- aryl
- epoxide
- Prior art date
Links
- 150000008378 aryl ethers Chemical class 0.000 title 1
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 abstract 2
- 150000001336 alkenes Chemical class 0.000 abstract 1
- 150000002118 epoxides Chemical class 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C07D301/03—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
- C07D301/14—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic peracids, or salts, anhydrides or esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11409298P | 1998-12-29 | 1998-12-29 | |
| PCT/US1999/030748 WO2000039072A1 (en) | 1998-12-29 | 1999-12-23 | Method for the preparation of aryl ethers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL144012A0 IL144012A0 (en) | 2002-04-21 |
| IL144012A true IL144012A (en) | 2005-11-20 |
Family
ID=22353332
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14401299A IL144012A (en) | 1998-12-29 | 1999-12-23 | Method for the preparation of aryl ethers |
| IL16184099A IL161840A0 (en) | 1998-12-29 | 1999-12-23 | Method for the preparation of aryl ethers |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16184099A IL161840A0 (en) | 1998-12-29 | 1999-12-23 | Method for the preparation of aryl ethers |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6376711B1 (zh) |
| EP (2) | EP1308443B1 (zh) |
| JP (1) | JP2002533430A (zh) |
| KR (2) | KR100616029B1 (zh) |
| CN (3) | CN100340552C (zh) |
| AT (2) | ATE260238T1 (zh) |
| AU (1) | AU764492B2 (zh) |
| BR (1) | BR9916615A (zh) |
| CA (1) | CA2349619A1 (zh) |
| CO (1) | CO5140125A1 (zh) |
| DE (2) | DE69940833D1 (zh) |
| DK (1) | DK1140788T3 (zh) |
| ES (1) | ES2214060T3 (zh) |
| HK (3) | HK1041688B (zh) |
| HU (1) | HUP0202144A3 (zh) |
| IL (2) | IL144012A (zh) |
| NZ (1) | NZ511452A (zh) |
| PE (1) | PE20001366A1 (zh) |
| PT (1) | PT1140788E (zh) |
| SI (1) | SI1140788T1 (zh) |
| TR (1) | TR200101885T2 (zh) |
| TW (1) | TWI238155B (zh) |
| WO (1) | WO2000039072A1 (zh) |
| ZA (1) | ZA200103532B (zh) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2796069B3 (fr) * | 1999-07-09 | 2001-08-24 | Sanofi Synthelabo | Nouveaux procedes de preparation de derives de 2-(2- arylmorpholin-2-yl)ethanol substitues, enantiomeriquement purs, et composes intermediaires utiles dans ces procedes |
| AR030284A1 (es) * | 2000-06-08 | 2003-08-20 | Merck & Co Inc | Proceso para la sintesis de (2r, 2-alfa-r,3a) -2-[1-(3,5-bis(trifluorometil) fenil) etoxi]-3-(4-fluorofenil)-1,4-oxazina; dicho compuesto y sus formas polimorficas |
| CN1922124A (zh) * | 2004-02-20 | 2007-02-28 | 法玛西雅厄普约翰公司 | 制备芳基醚的方法 |
| WO2005082869A1 (en) * | 2004-02-20 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Method for the preparation of aryl ethers |
| WO2005095435A1 (ja) * | 2004-03-31 | 2005-10-13 | Kuraray Co., Ltd. | プレグナン誘導体の製造方法 |
| GB0409744D0 (en) * | 2004-04-30 | 2004-06-09 | Pfizer Ltd | Novel compounds |
| AP2006003771A0 (en) * | 2004-04-30 | 2006-10-31 | Warner Lambert Co | Substituted morpholine compounds for the treatmentof central nervous system disorders |
| PT2076508E (pt) | 2006-10-18 | 2011-03-07 | Pfizer Prod Inc | Compostos de ureia de éter biarílico |
| US20100069389A1 (en) * | 2008-09-06 | 2010-03-18 | Bionevia Pharmaceuticals, Inc. | Novel forms of reboxetine |
| CN103804316A (zh) * | 2012-11-13 | 2014-05-21 | 天津药物研究院 | 一种（2RS,3RS）-6-[a-（2-乙氧基苯氧基）苄基]吗啉-3-酮（Ⅰ）的制备方法 |
| CN104557936A (zh) * | 2015-01-15 | 2015-04-29 | 河南科技学院 | 一种新型手性非环嘌呤核苷类似物的合成方法 |
| US20190381056A1 (en) | 2018-06-17 | 2019-12-19 | Axsome Therapeutics, Inc. | Compositions for delivery of reboxetine |
| US20200147093A1 (en) | 2018-10-15 | 2020-05-14 | Axsome Therapeutics, Inc. | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2785185A (en) * | 1952-08-07 | 1957-03-12 | Union Carbide & Carbon Corp | Process for making oxirane compounds from olefins and aldehyde monoperacylates |
| GB1053972A (zh) * | 1962-08-30 | 1967-01-04 | ||
| IL56369A (en) * | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
| GB8419683D0 (en) * | 1984-08-02 | 1984-09-05 | Erba Farmitalia | 3-substituted derivatives of 1-amino-2-hydroxy-propane |
-
1999
- 1999-12-23 BR BR9916615-1A patent/BR9916615A/pt not_active Application Discontinuation
- 1999-12-23 DE DE69940833T patent/DE69940833D1/de not_active Expired - Fee Related
- 1999-12-23 AU AU23819/00A patent/AU764492B2/en not_active Ceased
- 1999-12-23 EP EP03002146A patent/EP1308443B1/en not_active Expired - Lifetime
- 1999-12-23 AT AT99967557T patent/ATE260238T1/de not_active IP Right Cessation
- 1999-12-23 KR KR1020067014909A patent/KR100616029B1/ko not_active IP Right Cessation
- 1999-12-23 EP EP99967557A patent/EP1140788B1/en not_active Expired - Lifetime
- 1999-12-23 KR KR1020017008269A patent/KR100616386B1/ko not_active IP Right Cessation
- 1999-12-23 IL IL14401299A patent/IL144012A/xx not_active IP Right Cessation
- 1999-12-23 ES ES99967557T patent/ES2214060T3/es not_active Expired - Lifetime
- 1999-12-23 CA CA002349619A patent/CA2349619A1/en not_active Abandoned
- 1999-12-23 WO PCT/US1999/030748 patent/WO2000039072A1/en active IP Right Grant
- 1999-12-23 PT PT99967557T patent/PT1140788E/pt unknown
- 1999-12-23 JP JP2000590985A patent/JP2002533430A/ja active Pending
- 1999-12-23 DE DE69915110T patent/DE69915110T2/de not_active Expired - Fee Related
- 1999-12-23 CN CNB2004100869263A patent/CN100340552C/zh not_active Expired - Fee Related
- 1999-12-23 NZ NZ511452A patent/NZ511452A/xx unknown
- 1999-12-23 IL IL16184099A patent/IL161840A0/xx not_active IP Right Cessation
- 1999-12-23 CN CNB998153028A patent/CN1308332C/zh not_active Expired - Fee Related
- 1999-12-23 HU HU0202144A patent/HUP0202144A3/hu unknown
- 1999-12-23 CN CNB2004100323697A patent/CN1249038C/zh not_active Expired - Fee Related
- 1999-12-23 AT AT03002146T patent/ATE430144T1/de not_active IP Right Cessation
- 1999-12-23 SI SI9930559T patent/SI1140788T1/xx unknown
- 1999-12-23 DK DK99967557T patent/DK1140788T3/da active
- 1999-12-23 US US09/469,429 patent/US6376711B1/en not_active Expired - Fee Related
- 1999-12-23 TR TR2001/01885T patent/TR200101885T2/xx unknown
- 1999-12-24 TW TW088122940A patent/TWI238155B/zh not_active IP Right Cessation
- 1999-12-28 CO CO99081078A patent/CO5140125A1/es unknown
- 1999-12-28 PE PE1999001328A patent/PE20001366A1/es not_active Application Discontinuation
-
2001
- 2001-05-02 ZA ZA200103532A patent/ZA200103532B/en unknown
-
2002
- 2002-05-04 HK HK02103399.9A patent/HK1041688B/zh not_active IP Right Cessation
-
2004
- 2004-11-10 HK HK04108874A patent/HK1066004A1/xx not_active IP Right Cessation
-
2005
- 2005-11-18 HK HK05110382A patent/HK1078572A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees |