HK1078572A1 - Method for the preparation of aryl ethers - Google Patents

Method for the preparation of aryl ethers

Info

Publication number
HK1078572A1
HK1078572A1 HK05110382A HK05110382A HK1078572A1 HK 1078572 A1 HK1078572 A1 HK 1078572A1 HK 05110382 A HK05110382 A HK 05110382A HK 05110382 A HK05110382 A HK 05110382A HK 1078572 A1 HK1078572 A1 HK 1078572A1
Authority
HK
Hong Kong
Prior art keywords
preparation
aryl ethers
ethers
aryl
epoxide
Prior art date
Application number
HK05110382A
Other languages
English (en)
Inventor
Kevin Henegar
Sarah Elizabeth Mancini
Keith Douglas Maisto
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of HK1078572A1 publication Critical patent/HK1078572A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66Methanesulfonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/321,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • C07D301/02Synthesis of the oxirane ring
    • C07D301/03Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
    • C07D301/14Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic peracids, or salts, anhydrides or esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK05110382A 1998-12-29 2005-11-18 Method for the preparation of aryl ethers HK1078572A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11409298P 1998-12-29 1998-12-29

Publications (1)

Publication Number Publication Date
HK1078572A1 true HK1078572A1 (en) 2006-03-17

Family

ID=22353332

Family Applications (3)

Application Number Title Priority Date Filing Date
HK02103399.9A HK1041688B (zh) 1998-12-29 2002-05-04 芳基醚的製備方法
HK04108874A HK1066004A1 (en) 1998-12-29 2004-11-10 Method for the preparation of aryl ethers
HK05110382A HK1078572A1 (en) 1998-12-29 2005-11-18 Method for the preparation of aryl ethers

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HK02103399.9A HK1041688B (zh) 1998-12-29 2002-05-04 芳基醚的製備方法
HK04108874A HK1066004A1 (en) 1998-12-29 2004-11-10 Method for the preparation of aryl ethers

Country Status (24)

Country Link
US (1) US6376711B1 (xx)
EP (2) EP1140788B1 (xx)
JP (1) JP2002533430A (xx)
KR (2) KR100616029B1 (xx)
CN (3) CN100340552C (xx)
AT (2) ATE260238T1 (xx)
AU (1) AU764492B2 (xx)
BR (1) BR9916615A (xx)
CA (1) CA2349619A1 (xx)
CO (1) CO5140125A1 (xx)
DE (2) DE69915110T2 (xx)
DK (1) DK1140788T3 (xx)
ES (1) ES2214060T3 (xx)
HK (3) HK1041688B (xx)
HU (1) HUP0202144A3 (xx)
IL (2) IL144012A (xx)
NZ (1) NZ511452A (xx)
PE (1) PE20001366A1 (xx)
PT (1) PT1140788E (xx)
SI (1) SI1140788T1 (xx)
TR (1) TR200101885T2 (xx)
TW (1) TWI238155B (xx)
WO (1) WO2000039072A1 (xx)
ZA (1) ZA200103532B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796069B3 (fr) * 1999-07-09 2001-08-24 Sanofi Synthelabo Nouveaux procedes de preparation de derives de 2-(2- arylmorpholin-2-yl)ethanol substitues, enantiomeriquement purs, et composes intermediaires utiles dans ces procedes
AR030284A1 (es) * 2000-06-08 2003-08-20 Merck & Co Inc Proceso para la sintesis de (2r, 2-alfa-r,3a) -2-[1-(3,5-bis(trifluorometil) fenil) etoxi]-3-(4-fluorofenil)-1,4-oxazina; dicho compuesto y sus formas polimorficas
BRPI0507917A (pt) * 2004-02-20 2007-07-10 Pharmacia & Upjohn Co Llc método para preparação de éteres de arila
WO2005082869A1 (en) * 2004-02-20 2005-09-09 Pharmacia & Upjohn Company Llc Method for the preparation of aryl ethers
WO2005095435A1 (ja) * 2004-03-31 2005-10-13 Kuraray Co., Ltd. プレグナン誘導体の製造方法
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
AU2005238296A1 (en) * 2004-04-30 2005-11-10 Warner-Lambert Company Llc Substituted morpholine compounds for the treatment of central nervous system disorders
DE602007011793D1 (de) 2006-10-18 2011-02-17 Pfizer Prod Inc Biaryl-ether-harnstoffverbindungen
US20100069389A1 (en) * 2008-09-06 2010-03-18 Bionevia Pharmaceuticals, Inc. Novel forms of reboxetine
CN103804316A (zh) * 2012-11-13 2014-05-21 天津药物研究院 一种(2RS,3RS)-6-[a-(2-乙氧基苯氧基)苄基]吗啉-3-酮(Ⅰ)的制备方法
CN104557936A (zh) * 2015-01-15 2015-04-29 河南科技学院 一种新型手性非环嘌呤核苷类似物的合成方法
US20190381056A1 (en) 2018-06-17 2019-12-19 Axsome Therapeutics, Inc. Compositions for delivery of reboxetine
US20200147093A1 (en) 2018-10-15 2020-05-14 Axsome Therapeutics, Inc. Use of esreboxetine to treat nervous system disorders such as fibromyalgia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785185A (en) * 1952-08-07 1957-03-12 Union Carbide & Carbon Corp Process for making oxirane compounds from olefins and aldehyde monoperacylates
GB1053972A (xx) * 1962-08-30 1967-01-04
IL56369A (en) * 1978-01-20 1984-05-31 Erba Farmitalia Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them
GB8419683D0 (en) 1984-08-02 1984-09-05 Erba Farmitalia 3-substituted derivatives of 1-amino-2-hydroxy-propane

Also Published As

Publication number Publication date
CN1636988A (zh) 2005-07-13
PT1140788E (pt) 2004-07-30
ES2214060T3 (es) 2004-09-01
CN1249038C (zh) 2006-04-05
CA2349619A1 (en) 2000-07-06
KR100616029B1 (ko) 2006-08-28
EP1140788A1 (en) 2001-10-10
KR20010099999A (ko) 2001-11-09
ATE430144T1 (de) 2009-05-15
ZA200103532B (en) 2002-08-02
HK1041688A1 (en) 2002-07-19
KR20060090310A (ko) 2006-08-10
IL161840A0 (en) 2005-11-20
EP1308443A2 (en) 2003-05-07
DE69915110D1 (de) 2004-04-01
HUP0202144A3 (en) 2003-10-28
DK1140788T3 (da) 2004-06-07
HUP0202144A2 (hu) 2002-11-28
HK1066004A1 (en) 2005-03-11
CO5140125A1 (es) 2002-03-22
HK1041688B (zh) 2007-12-07
WO2000039072A1 (en) 2000-07-06
AU2381900A (en) 2000-07-31
SI1140788T1 (en) 2004-08-31
NZ511452A (en) 2002-11-26
JP2002533430A (ja) 2002-10-08
ATE260238T1 (de) 2004-03-15
CN100340552C (zh) 2007-10-03
DE69915110T2 (de) 2004-08-26
PE20001366A1 (es) 2000-11-19
EP1308443B1 (en) 2009-04-29
CN1532194A (zh) 2004-09-29
EP1308443A3 (en) 2003-10-01
CN1308332C (zh) 2007-04-04
AU764492B2 (en) 2003-08-21
US6376711B1 (en) 2002-04-23
TR200101885T2 (tr) 2002-01-21
DE69940833D1 (de) 2009-06-10
EP1140788B1 (en) 2004-02-25
CN1332719A (zh) 2002-01-23
IL144012A0 (en) 2002-04-21
IL144012A (en) 2005-11-20
KR100616386B1 (ko) 2006-08-28
TWI238155B (en) 2005-08-21
BR9916615A (pt) 2001-10-23

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20111223