IL143112A0 - A method for enhancing protective cellular responses to genotoxic stress in skin - Google Patents

A method for enhancing protective cellular responses to genotoxic stress in skin

Info

Publication number
IL143112A0
IL143112A0 IL14311299A IL14311299A IL143112A0 IL 143112 A0 IL143112 A0 IL 143112A0 IL 14311299 A IL14311299 A IL 14311299A IL 14311299 A IL14311299 A IL 14311299A IL 143112 A0 IL143112 A0 IL 143112A0
Authority
IL
Israel
Prior art keywords
skin
cellular responses
genotoxic stress
protective cellular
enhancing protective
Prior art date
Application number
IL14311299A
Other languages
English (en)
Original Assignee
Univ Kentucky Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22333250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL143112(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Kentucky Res Found filed Critical Univ Kentucky Res Found
Publication of IL143112A0 publication Critical patent/IL143112A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
IL14311299A 1998-12-01 1999-12-01 A method for enhancing protective cellular responses to genotoxic stress in skin IL143112A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11048298P 1998-12-01 1998-12-01
PCT/US1999/028446 WO2000032179A2 (en) 1998-12-01 1999-12-01 Use of nicotonic acid derivatives for the treatment of dna damage in skin cells

Publications (1)

Publication Number Publication Date
IL143112A0 true IL143112A0 (en) 2002-04-21

Family

ID=22333250

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14311299A IL143112A0 (en) 1998-12-01 1999-12-01 A method for enhancing protective cellular responses to genotoxic stress in skin
IL143112A IL143112A (en) 1998-12-01 2001-05-13 Method for enhancing protective cellular responses to genotoxic stress in skin

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL143112A IL143112A (en) 1998-12-01 2001-05-13 Method for enhancing protective cellular responses to genotoxic stress in skin

Country Status (15)

Country Link
US (4) US6337065B1 (da)
EP (1) EP1143954B1 (da)
AR (1) AR023715A1 (da)
AT (1) ATE273008T1 (da)
AU (1) AU762770B2 (da)
CA (1) CA2352964C (da)
DE (1) DE69919403T2 (da)
DK (1) DK1143954T3 (da)
ES (1) ES2228146T3 (da)
HK (1) HK1041436B (da)
IL (2) IL143112A0 (da)
NZ (1) NZ511708A (da)
PT (1) PT1143954E (da)
TW (1) TWI257303B (da)
WO (1) WO2000032179A2 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1143954E (pt) * 1998-12-01 2004-12-31 Univ Kentucky Res Found Utilizacao de derivados de acido nocotinico para o tratamento de danos no adn em celulas da pele
US20020054895A1 (en) 1999-07-23 2002-05-09 Alwyn Company, Inc. Allantoin-containing skin cream
US6673826B2 (en) 1999-07-23 2004-01-06 Alwyn Company, Inc. Methods for treatment of inflammatory diseases
US6896897B2 (en) 1999-07-23 2005-05-24 Alwyn Company, Inc. Flexible applicator for applying oil-in-water emulsion with improved stability
US6531500B2 (en) 1999-07-23 2003-03-11 Alwyn Company, Inc. Methods for treatment of inflammatory diseases
US6864274B2 (en) 1999-07-23 2005-03-08 Alwyn Company, Inc. Allantoin-containing skin cream
DK1272183T3 (da) * 2000-04-14 2006-11-27 Niadyne Corp Fremgangsmåder og sammensætninger der er nyttige til forögelse af oxygentilförsel til celler
US6677361B2 (en) * 2000-04-14 2004-01-13 University Of Kentucky Research Foundation Topical formulations for the transdermal delivery of niacin and methods of treating hyperlipidemia
US20020182585A1 (en) * 2001-01-10 2002-12-05 George Kindness Combination and method using EDTA, cystine, zinc and selenium for anti-thrombin effect and for anti-platelet aggregation and measurement of efficacy
ATE409037T1 (de) * 2001-03-08 2008-10-15 Univ Kentucky Res Found Verfahren zur erhöhung der leptinspiegel unter verwendung von nikotinsäureverbindungen
ITMI20011019A1 (it) * 2001-05-17 2002-11-17 Carlo Ghisalberti Sostanze furiliche per uso topico
AU2002950744A0 (en) * 2002-08-13 2002-09-12 Medihoney Pty Ltd Composition
US7326690B2 (en) * 2002-10-30 2008-02-05 Bach Pharma, Inc. Modulation of cell fates and activities by phthalazinediones
WO2004056307A2 (en) * 2002-12-19 2004-07-08 Yitzchak Hillman Disease treatment via antimicrobial peptide inhibitors
KR20050089857A (ko) * 2002-12-26 2005-09-08 아지노모토 가부시키가이샤 간암 발생 및 진행 억제제
US20040161435A1 (en) * 2003-02-14 2004-08-19 Gupta Shyam K. Skin Firming Anti-Aging Cosmetic Mask Compositions
JP4299299B2 (ja) 2003-05-19 2009-07-22 株式会社ジーンケア研究所 癌細胞に対するアポトーシス誘導剤
US8338648B2 (en) * 2004-06-12 2012-12-25 Signum Biosciences, Inc. Topical compositions and methods for epithelial-related conditions
US7615641B2 (en) * 2004-07-20 2009-11-10 Sino Pharmaceuticals Corporation Long chain aliphatic alcohol derivatives and methods of making and using same
ES2646512T3 (es) 2005-06-24 2017-12-14 Arizona Board Of Regents, Acting On Behalf Of The University Of Arizona Método para el tratamiento de trastornos del crecimiento del cabello, tales como la alopecia de patrón femenino, y composiciones útiles para el mismo
WO2007136744A1 (en) * 2006-05-19 2007-11-29 The Johns Hopkins University Crystal structure of a substrate complex of nampt/pbef/visfatin
US20070293458A1 (en) * 2006-06-16 2007-12-20 Ip-6 Research Inc. Prevention of nuclear, solar, and other radiation-induced tissue damage
WO2008025755A1 (de) * 2006-09-01 2008-03-06 Basf Se Verwendung von n-haltigen heterozyklen in dermokosmetika
CA2673459C (en) * 2006-12-22 2016-09-13 Stefan Schulte Modified coagulation factors with prolonged in vivo half-life
ES2458566T3 (es) * 2007-02-28 2014-05-06 University Of Kentucky Research Foundation Procedimiento para aliviar los efectos secundarios de la terapia con ácido retinoico y/o mejorar la eficacia sin interferir en la eficacia
EP2259782A4 (en) * 2008-03-03 2013-01-23 Nad Life Pty Ltd PHARMACEUTICAL FORMULATIONS OF RESVERATROL AND METHOD FOR THEIR USE IN THE TREATMENT OF CELL DISEASES
EP2168574A1 (en) 2008-09-25 2010-03-31 Noureddine Frid Compound for local deletion of tumors
US8173446B2 (en) 2009-12-21 2012-05-08 General Electric Company Method of producing an integrated micromagnet sensor assembly
US20140135372A1 (en) 2010-02-02 2014-05-15 Elliott Farber Compositions and methods of treatment of inflammatory skin conditions using allantoin
WO2012114204A2 (en) 2011-02-15 2012-08-30 Ecole Polytechnique Federale De Lausanne (Epfl) Epfl-Tto Methods of treating mitochondrial dysfunction
EP3152220A1 (en) 2014-06-06 2017-04-12 Glaxosmithkline Intellectual Property (No. 2) Limited Nicotinamide riboside analogs and pharmaceutical compositions and uses thereof
US11845928B2 (en) * 2015-05-04 2023-12-19 Tsinghua University Methods and kits for fragmenting DNA
US11344497B1 (en) 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
US10722465B1 (en) 2017-12-08 2020-07-28 Quicksilber Scientific, Inc. Transparent colloidal vitamin supplement
EP3873415A1 (en) 2018-11-02 2021-09-08 Unilever Global Ip Limited Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same
US11291702B1 (en) 2019-04-15 2022-04-05 Quicksilver Scientific, Inc. Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3185679A (en) 1965-05-25 Azepine derivatives
US3276960A (en) 1961-08-21 1966-10-04 Kendall & Co Analgesic methods and compositions
US4246285A (en) 1975-10-20 1981-01-20 The Procter & Gamble Company Skin conditioning compositions containing guanidine inorganic salts
HU184626B (en) 1979-06-01 1984-09-28 Ferrokemia Ipari Congesting cosmetics first of all hair-restorers
DE3174885D1 (en) 1981-02-03 1986-07-31 Ici Plc Process for the extraction of metal values and novel metal extractants
US4607101A (en) 1981-08-27 1986-08-19 Jaye-Boern Laboratories, Inc. Method of treating acne vulgaris with a composition containing carbamide peroxide
US5635497A (en) 1982-06-23 1997-06-03 Yamanouchi Europe B.V. Topical application compositions
US4459153A (en) 1982-09-20 1984-07-10 The United States Of America As Represented By The United States Department Of Energy Pyrochemical process for extracting plutonium from an electrolyte salt
US4474753A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Topical drug delivery system utilizing thermosetting gels
ATE55905T1 (de) 1984-03-07 1990-09-15 Roshdy Ismail Mittel zur behandlung und zum schutz der haut.
US4665192A (en) 1984-03-19 1987-05-12 The Rockefeller University 2-(2-furoyl)-4(5)-2(furanyl)-1H-imidazole
US4758583A (en) 1984-03-19 1988-07-19 The Rockefeller University Method and agents for inhibiting protein aging
EP0182635B1 (en) 1984-11-15 1989-05-31 Nitto Denko Corporation Composition for percutaneous administration
US5053396A (en) * 1985-08-27 1991-10-01 Blass David H Therapeutic composition
DE3532562A1 (de) 1985-09-12 1987-03-12 Dolorgiet Gmbh & Co Kg Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben
LU86574A1 (fr) 1986-09-08 1988-04-05 Oreal Composition pour induire et stimuler la croissance des cheveux et freiner leur chute,a base d'esters nicotiniques et de derives de pyrimidine
GB2216003B (en) 1988-02-18 1992-06-10 Toyama Chemical Co Ltd Hair restorer
US4981681A (en) 1988-08-26 1991-01-01 Vittorio Tosti Lotion mixture and method of treating psoriasis
US5077313A (en) 1988-11-25 1991-12-31 Gert Lubec Process for inhibiting pathological collagen cross-linking in diabetes patients
US5133958A (en) 1989-04-20 1992-07-28 Erwin Stuckler Agent for nail, skin and hair care
US5129360A (en) 1990-01-24 1992-07-14 The United States Of America As Represented By The Secretary Of The Air Force Actively cooled effusion cell for chemical vapor deposition
GB9006785D0 (en) 1990-03-27 1990-05-23 Leung Lit Hung Composition and methods for treatment of acne vulgaris and retardation of ageing
US5114957A (en) 1990-05-08 1992-05-19 Biodor U.S. Holding Tocopherol-based antiviral agents and method of using same
US5043162A (en) 1990-09-05 1991-08-27 Trager Seymour F Hair growth promoter
FR2668366B1 (fr) * 1990-10-30 1993-01-29 Oreal Utilisation cosmetique d'une composition ayant une activite antierythemale et composition correspondante.
GB9114346D0 (en) 1991-07-03 1991-08-21 Dow Corning Sa A method of accelerating drug permeation
US5358969A (en) 1991-12-16 1994-10-25 Washington University Method of inhibiting nitric oxide formation
US5240945A (en) 1992-02-18 1993-08-31 Warshaw Thelma G Method and compositions for treating acne
US5318960A (en) 1992-06-03 1994-06-07 Frank Toppo System for transdermal delivery of pain relieving substances
US5449688A (en) 1993-03-30 1995-09-12 The United States Of America As Represented By The Department Of Health And Human Services Method of treating chronic inflammatory diseases
US6231852B1 (en) * 1993-11-18 2001-05-15 The Regents Of The University Of California Method for reducing BCL-2 expressing cells resistance to death
FR2715565B1 (fr) 1994-01-31 1996-03-15 Oreal Composition cosmétique ou dermatologique stabilisée contenant plusieurs précurseurs d'un même actif pour maximaliser sa libération, son utilisation.
GB9404485D0 (en) 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues
JP3455544B2 (ja) * 1994-06-02 2003-10-14 リガ ダン 抗ストレス剤、抗機能障害剤および抗老化剤、ならびに該薬剤の製造法
US5612382A (en) 1994-07-15 1997-03-18 Frances B. Fike Composition for percutaneous absorption of pharmaceutically active ingredients
US5496827A (en) * 1994-07-15 1996-03-05 Patrick; Jay Compositions for the transdermal delivery of nutrients
DE4433130C2 (de) 1994-09-16 1997-02-06 Deutsches Krebsforsch Poly(ADP-Ribose)-Polymerase überexprimierende tierische Zellinien und Verfahren zur Identifizierung von DNA-schädigenden Substanzen
DE69533714T2 (de) 1994-12-20 2005-03-24 Unilever N.V. Lactat-dehydrogenase Inhibitoren in kosmetischen Mitteln
US5690944A (en) 1994-12-20 1997-11-25 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Cosmetic compositions containing lactate dehydrogenase inhibitors
EP0814812A1 (en) * 1995-03-14 1998-01-07 Edward G. Shaskan Compositions comprising nicotynylalanine and an inhibitor of glycine conjugation or vitamin b6
CA2220091C (en) 1995-05-01 2011-01-04 Scotia Holdings Plc Nicotinic acid esters and pharmaceutical compositions containing them
JPH08301760A (ja) * 1995-05-10 1996-11-19 Shiseido Co Ltd 皮膚外用剤
US5571794A (en) 1995-06-22 1996-11-05 Frome; Bruce M. Non-invasive novel method fo cosmetic lip augmentation
JP3542665B2 (ja) 1995-07-07 2004-07-14 株式会社資生堂 抗老化皮膚外用剤、コラーゲン架橋阻害皮膚外用剤及び抗紫外線皮膚外用剤
DE69634404T2 (de) * 1995-08-14 2005-12-29 Optigenex, Inc. Caroteinoid-nicotinamid-zink zusammensetzungen und verfahren zur behandlung unter verwendung derselben
US5939082A (en) * 1995-11-06 1999-08-17 The Procter & Gamble Company Methods of regulating skin appearance with vitamin B3 compound
CZ235798A3 (cs) * 1996-01-24 1999-03-17 Aliatros Medical, A. S. Prostředek pro léčení rakoviny a způsob jeho výroby
US5736529A (en) * 1996-03-22 1998-04-07 Neurocal International Inc. Use of NAD-related compounds in the treatment of neural trauma to inhibit neurodegeneration
AUPN892496A0 (en) * 1996-03-25 1996-04-18 Technical Consultancy Services Pty Limited Acne treatment
US5693671A (en) * 1996-05-01 1997-12-02 Harbor-Ucla Research And Education Institute L-glutamine therapy for sickle cell diseases and thalassemia
CN1293562A (zh) * 1998-03-16 2001-05-02 宝洁公司 减轻哺乳动物蜂窝炎的方法
US6277613B1 (en) 1998-06-10 2001-08-21 The Rockefeller University TRF1 binding protein, methods of use thereof
US6149924A (en) * 1998-07-20 2000-11-21 Biomed Research & Technologies, Inc. Composition for enhancing lipid production, barrier function, hydrogen peroxide neutralization, and moisturization of the skin
US5976513A (en) 1998-10-16 1999-11-02 The Procter & Gamble Company UV protection compositions
PT1143954E (pt) * 1998-12-01 2004-12-31 Univ Kentucky Res Found Utilizacao de derivados de acido nocotinico para o tratamento de danos no adn em celulas da pele

Also Published As

Publication number Publication date
US7425319B2 (en) 2008-09-16
EP1143954A2 (en) 2001-10-17
ATE273008T1 (de) 2004-08-15
NZ511708A (en) 2003-12-19
AR023715A1 (es) 2002-09-04
DK1143954T3 (da) 2004-12-20
ES2228146T3 (es) 2005-04-01
IL143112A (en) 2006-10-31
WO2000032179A2 (en) 2000-06-08
HK1041436B (zh) 2005-03-11
US6403619B1 (en) 2002-06-11
WO2000032179A3 (en) 2001-12-13
PT1143954E (pt) 2004-12-31
EP1143954B1 (en) 2004-08-11
CA2352964A1 (en) 2000-06-08
HK1041436A1 (en) 2002-07-12
US6337065B1 (en) 2002-01-08
TWI257303B (en) 2006-07-01
US6552050B2 (en) 2003-04-22
DE69919403T2 (de) 2005-09-08
US20010033848A1 (en) 2001-10-25
AU762770B2 (en) 2003-07-03
CA2352964C (en) 2006-10-17
US20040147491A1 (en) 2004-07-29
DE69919403D1 (de) 2004-09-16
AU1929200A (en) 2000-06-19

Similar Documents

Publication Publication Date Title
IL143112A0 (en) A method for enhancing protective cellular responses to genotoxic stress in skin
ZA988307B (en) A method for maintaining or improving skin health
HUP0004677A3 (en) A method for improving skin condition
GB2355557B (en) Method and apparatus to connect consumer to expert
GB0312806D0 (en) Improvement in and relating to gratings
HK1042149A1 (zh) 與自動交易相關的方法和設備
SG92612A1 (en) Cushioning conversion machine and method
AU3762899A (en) Training dummy assembly in human form
ATE258219T1 (de) Verfahren zum vermindern des zerknitterten aussehens
GB2305268B (en) Pulsed-tone timing exercise method
IL111172A0 (en) Shoes for reducing stress in feet
KR960013593A (ko) 전기화학적인 방법을 이용하여 제품을 천공하는 방법
SG94865A1 (en) Method to reduce variation in ldd series resistance
GB2346222B (en) Machine simulation method and apparatus
GB9902041D0 (en) Method for increasing muscle mass in animals
EP1211341A4 (en) METHOD FOR SEWING A HEM WITH EXCELLENT EXTENSIBILITY
IL114693A0 (en) Cushioning conversion machine and method
GB9713979D0 (en) Method for attaching peg to macromolecules
GB2358706B (en) Method for evaluating skin health
DE69531611D1 (en) Lactone-stabile camptothecin oder 7 - ethyl camptothecin - formulierung in dimethylisosorbid oder dimethylacetamid
GB0006867D0 (en) Method and composition for skin lightening
IL136452A0 (en) Method and arrangement relating to antennas
IL128312A0 (en) A method to prepare dihydrothiazoles
EG22097A (en) A method for improving skin condition
GB2389664B (en) Method for evaluating skin health

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed