IL143082A - Benzofuran derivatives, their preparation and use - Google Patents
Benzofuran derivatives, their preparation and useInfo
- Publication number
- IL143082A IL143082A IL14308299A IL14308299A IL143082A IL 143082 A IL143082 A IL 143082A IL 14308299 A IL14308299 A IL 14308299A IL 14308299 A IL14308299 A IL 14308299A IL 143082 A IL143082 A IL 143082A
- Authority
- IL
- Israel
- Prior art keywords
- propyl
- fluorophenyl
- carbonitrile
- indol
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11136098P | 1998-12-08 | 1998-12-08 | |
| DKPA199801631 | 1998-12-09 | ||
| PCT/DK1999/000676 WO2000034263A1 (en) | 1998-12-08 | 1999-12-03 | Benzofuran derivatives, their preparation and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL143082A0 IL143082A0 (en) | 2002-04-21 |
| IL143082A true IL143082A (en) | 2004-06-20 |
Family
ID=43768792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14308299A IL143082A (en) | 1998-12-08 | 1999-12-03 | Benzofuran derivatives, their preparation and use |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1137644B9 (da) |
| JP (1) | JP2002531556A (da) |
| AR (1) | AR021509A1 (da) |
| AT (1) | ATE249451T1 (da) |
| AU (1) | AU759248B2 (da) |
| CA (1) | CA2353618A1 (da) |
| CZ (1) | CZ20012041A3 (da) |
| DE (1) | DE69911243T2 (da) |
| DK (1) | DK1137644T3 (da) |
| ES (1) | ES2204175T3 (da) |
| HU (1) | HUP0104510A3 (da) |
| IL (1) | IL143082A (da) |
| ME (1) | MEP38508A (da) |
| PT (1) | PT1137644E (da) |
| RS (1) | RS50065B (da) |
| SE (1) | SE1137644T5 (da) |
| SI (1) | SI1137644T1 (da) |
| WO (1) | WO2000034263A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR021155A1 (es) * | 1999-07-08 | 2002-06-12 | Lundbeck & Co As H | Tratamiento de desordenes neuroticos |
| EA008372B1 (ru) * | 2000-07-07 | 2007-04-27 | Х.Лундбекк А/С | Применение эсциталопрама для лечения расстройства, связанного с социальной тревогой |
| EA008373B1 (ru) * | 2000-07-07 | 2007-04-27 | Х. Лундбекк А/С | Применение эсциталопрама для лечения расстройства, связанного с посттравматическим стрессом |
| CA2416447A1 (en) * | 2000-07-21 | 2002-01-31 | H. Lundbeck A/S | Novel compounds and their use as glycine transport inhibitors |
| AU2001288605A1 (en) * | 2000-09-06 | 2002-03-22 | Chugai Seiyaku Kabushiki Kaisha | A traceless solid-phase synthesis of 2-imidazolones |
| US7235569B2 (en) | 2003-05-02 | 2007-06-26 | Wyeth | Piperidinyl indole and tetrohydropyridinyl indole derivatives and method of their use |
| US7276603B2 (en) | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
| US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
| EP2970177A1 (en) | 2013-03-15 | 2016-01-20 | Pfizer Inc. | Indole compounds that activate ampk |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1143703A (da) * | 1965-03-18 | |||
| GB1173312A (en) * | 1966-03-17 | 1969-12-10 | Kefalas As | Heterocyclic Compounds |
| GB1526331A (en) * | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
| US5877317A (en) * | 1993-12-28 | 1999-03-02 | Pharmacia & Upjohn Company | Heterocyclic compounds for the treatment of CNS and cardiovascular disorders |
| ZA954689B (en) * | 1994-06-08 | 1996-01-29 | Lundbeck & Co As H | 4-Aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzothiophenemethyl) piperidines tetrahydropyridines or piperazines |
-
1999
- 1999-12-01 AR ARP990106110A patent/AR021509A1/es unknown
- 1999-12-03 IL IL14308299A patent/IL143082A/en not_active IP Right Cessation
- 1999-12-03 SI SI9930412T patent/SI1137644T1/xx unknown
- 1999-12-03 DK DK99957263T patent/DK1137644T3/da active
- 1999-12-03 HU HU0104510A patent/HUP0104510A3/hu unknown
- 1999-12-03 EP EP99957263A patent/EP1137644B9/en not_active Expired - Lifetime
- 1999-12-03 AT AT99957263T patent/ATE249451T1/de not_active IP Right Cessation
- 1999-12-03 DE DE69911243T patent/DE69911243T2/de not_active Expired - Fee Related
- 1999-12-03 AU AU15036/00A patent/AU759248B2/en not_active Ceased
- 1999-12-03 SE SE99957263T patent/SE1137644T5/xx unknown
- 1999-12-03 RS YUP-384/01A patent/RS50065B/sr unknown
- 1999-12-03 CZ CZ20012041A patent/CZ20012041A3/cs unknown
- 1999-12-03 PT PT99957263T patent/PT1137644E/pt unknown
- 1999-12-03 WO PCT/DK1999/000676 patent/WO2000034263A1/en active IP Right Grant
- 1999-12-03 ME MEP-385/08A patent/MEP38508A/xx unknown
- 1999-12-03 CA CA002353618A patent/CA2353618A1/en not_active Abandoned
- 1999-12-03 JP JP2000586710A patent/JP2002531556A/ja active Pending
- 1999-12-03 ES ES99957263T patent/ES2204175T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1137644E (pt) | 2004-01-30 |
| ES2204175T3 (es) | 2004-04-16 |
| MEP38508A (en) | 2011-02-10 |
| YU38401A (sh) | 2005-06-10 |
| EP1137644B1 (en) | 2003-09-10 |
| AU1503600A (en) | 2000-06-26 |
| SE1137644T3 (da) | 2003-12-02 |
| HUP0104510A3 (en) | 2003-01-28 |
| SE1137644T5 (da) | 2004-05-11 |
| JP2002531556A (ja) | 2002-09-24 |
| CZ20012041A3 (cs) | 2001-10-17 |
| DE69911243D1 (de) | 2003-10-16 |
| RS50065B (sr) | 2009-01-22 |
| WO2000034263A1 (en) | 2000-06-15 |
| AU759248B2 (en) | 2003-04-10 |
| CA2353618A1 (en) | 2000-06-15 |
| DE69911243T2 (de) | 2004-07-15 |
| DK1137644T3 (da) | 2003-12-08 |
| EP1137644A1 (en) | 2001-10-04 |
| AR021509A1 (es) | 2002-07-24 |
| ATE249451T1 (de) | 2003-09-15 |
| EP1137644B9 (en) | 2004-03-17 |
| HUP0104510A2 (hu) | 2002-04-29 |
| IL143082A0 (en) | 2002-04-21 |
| SI1137644T1 (en) | 2003-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |