IL141655A0 - A process for the preparation of midodrine - Google Patents
A process for the preparation of midodrineInfo
- Publication number
- IL141655A0 IL141655A0 IL14165501A IL14165501A IL141655A0 IL 141655 A0 IL141655 A0 IL 141655A0 IL 14165501 A IL14165501 A IL 14165501A IL 14165501 A IL14165501 A IL 14165501A IL 141655 A0 IL141655 A0 IL 141655A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- midodrine
- dimethoxyphenyl
- chem
- formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- PTKSEFOSCHHMPD-SNVBAGLBSA-N 2-amino-n-[(2s)-2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide Chemical compound COC1=CC=C(OC)C([C@H](O)CNC(=O)CN)=C1 PTKSEFOSCHHMPD-SNVBAGLBSA-N 0.000 title 1
- 229960001094 midodrine Drugs 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL14165501A IL141655A0 (en) | 2001-02-26 | 2001-02-26 | A process for the preparation of midodrine |
CA002366311A CA2366311A1 (en) | 2001-02-26 | 2001-12-31 | A process for the preparation of midodrine |
HU0200034A HUP0200034A2 (hu) | 2001-02-26 | 2002-01-04 | Eljárás midodrin előállítására és intermedierje |
US10/040,385 US6444851B1 (en) | 2001-02-26 | 2002-01-09 | Process for the preparation of Midodrine |
CZ2002138A CZ2002138A3 (cs) | 2001-02-26 | 2002-01-11 | Způsob přípravy midodrinu a meziprodukt tohoto způsobu |
DE60200406T DE60200406T2 (de) | 2001-02-26 | 2002-02-07 | Verfahren zur Herstellung von Midodrin |
EP02002042A EP1234817B1 (en) | 2001-02-26 | 2002-02-07 | A process for the preparation of midodrine |
AT02002042T ATE265421T1 (de) | 2001-02-26 | 2002-02-07 | Verfahren zur herstellung von midodrin |
JP2002030646A JP2002255915A (ja) | 2001-02-26 | 2002-02-07 | ミドドリンの製法 |
PT02002042T PT1234817E (pt) | 2001-02-26 | 2002-02-07 | Processo para a preparacao de midodrina |
PL02352455A PL352455A1 (en) | 2001-02-26 | 2002-02-25 | Method of obtaining midodrin hydrochloride |
US10/206,968 US6610886B2 (en) | 2001-02-26 | 2002-07-30 | Intermediate for preparing midodrine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL14165501A IL141655A0 (en) | 2001-02-26 | 2001-02-26 | A process for the preparation of midodrine |
Publications (1)
Publication Number | Publication Date |
---|---|
IL141655A0 true IL141655A0 (en) | 2002-03-10 |
Family
ID=11075177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14165501A IL141655A0 (en) | 2001-02-26 | 2001-02-26 | A process for the preparation of midodrine |
Country Status (11)
Country | Link |
---|---|
US (2) | US6444851B1 (cs) |
EP (1) | EP1234817B1 (cs) |
JP (1) | JP2002255915A (cs) |
AT (1) | ATE265421T1 (cs) |
CA (1) | CA2366311A1 (cs) |
CZ (1) | CZ2002138A3 (cs) |
DE (1) | DE60200406T2 (cs) |
HU (1) | HUP0200034A2 (cs) |
IL (1) | IL141655A0 (cs) |
PL (1) | PL352455A1 (cs) |
PT (1) | PT1234817E (cs) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2421550C (en) * | 2003-03-11 | 2008-06-03 | Brantford Chemicals Inc. | Process for the preparation of midodrine, pharmaceutically-acceptable salts thereof and intermediates |
US20070082070A1 (en) * | 2005-10-11 | 2007-04-12 | Stookey Evangeline L | Treating skin disorders |
JP2010523483A (ja) * | 2007-03-30 | 2010-07-15 | ビーエーエスエフ ソシエタス・ヨーロピア | ポリオキシジアルキルエーテルからの環状ホルムアルデヒド誘導体の製造方法 |
KR101356471B1 (ko) | 2011-12-09 | 2014-01-29 | 고려대학교 산학협력단 | 고혈압 예방 및 치료용 화합물 |
US12032578B1 (en) * | 2023-01-24 | 2024-07-09 | Sap Se | Data compression, store, and search system |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT241435B (de) * | 1963-06-11 | 1965-07-26 | Chemie Linz Ag | Verfahren zur Herstellung von neuen Phenylalkanolaminderivaten und deren Salzen |
AT336584B (de) * | 1975-02-25 | 1977-05-10 | Chemie Linz Ag | Verfahren zur herstellung von 1-phenyl-2-glycinamidoathanolen- (1) und von deren salzen |
JPH07285921A (ja) * | 1994-04-15 | 1995-10-31 | Sanyo Kagaku Kenkyusho:Kk | 2−アミノ−N−(β−ヒドロキシフェネチル)アセトアミド誘導体の製造方法 |
-
2001
- 2001-02-26 IL IL14165501A patent/IL141655A0/xx unknown
- 2001-12-31 CA CA002366311A patent/CA2366311A1/en not_active Abandoned
-
2002
- 2002-01-04 HU HU0200034A patent/HUP0200034A2/hu unknown
- 2002-01-09 US US10/040,385 patent/US6444851B1/en not_active Expired - Fee Related
- 2002-01-11 CZ CZ2002138A patent/CZ2002138A3/cs unknown
- 2002-02-07 DE DE60200406T patent/DE60200406T2/de not_active Expired - Lifetime
- 2002-02-07 AT AT02002042T patent/ATE265421T1/de not_active IP Right Cessation
- 2002-02-07 EP EP02002042A patent/EP1234817B1/en not_active Expired - Lifetime
- 2002-02-07 PT PT02002042T patent/PT1234817E/pt unknown
- 2002-02-07 JP JP2002030646A patent/JP2002255915A/ja active Pending
- 2002-02-25 PL PL02352455A patent/PL352455A1/xx not_active IP Right Cessation
- 2002-07-30 US US10/206,968 patent/US6610886B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6444851B1 (en) | 2002-09-03 |
CA2366311A1 (en) | 2002-08-26 |
US20020193635A1 (en) | 2002-12-19 |
HUP0200034A2 (hu) | 2002-12-28 |
EP1234817B1 (en) | 2004-04-28 |
DE60200406D1 (de) | 2004-06-03 |
DE60200406T2 (de) | 2004-09-02 |
JP2002255915A (ja) | 2002-09-11 |
ATE265421T1 (de) | 2004-05-15 |
US20020128511A1 (en) | 2002-09-12 |
EP1234817A1 (en) | 2002-08-28 |
US6610886B2 (en) | 2003-08-26 |
CZ2002138A3 (cs) | 2002-10-16 |
HU0200034D0 (en) | 2002-03-28 |
PL352455A1 (en) | 2002-09-09 |
PT1234817E (pt) | 2004-08-31 |
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