IL141164A0 - 1,2 tricyclic tetrahydroisoquinoline compounds indicated to be useful in the treatment and prophylaxis of epilepsy, migraine and other disorders - Google Patents
1,2 tricyclic tetrahydroisoquinoline compounds indicated to be useful in the treatment and prophylaxis of epilepsy, migraine and other disordersInfo
- Publication number
- IL141164A0 IL141164A0 IL14116499A IL14116499A IL141164A0 IL 141164 A0 IL141164 A0 IL 141164A0 IL 14116499 A IL14116499 A IL 14116499A IL 14116499 A IL14116499 A IL 14116499A IL 141164 A0 IL141164 A0 IL 141164A0
- Authority
- IL
- Israel
- Prior art keywords
- migraine
- epilepsy
- tricyclic
- prophylaxis
- disorders
- Prior art date
Links
- 208000019695 Migraine disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 206010015037 epilepsy Diseases 0.000 title 1
- 206010027599 migraine Diseases 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 125000003039 tetrahydroisoquinolinyl group Chemical class C1(NCCC2=CC=CC=C12)* 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9817028.5A GB9817028D0 (en) | 1998-08-05 | 1998-08-05 | Novel compounds |
| PCT/EP1999/005584 WO2000008020A2 (en) | 1998-08-05 | 1999-08-03 | Tricyclic carboxamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL141164A0 true IL141164A0 (en) | 2002-11-10 |
Family
ID=10836742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14116499A IL141164A0 (en) | 1998-08-05 | 1999-08-03 | 1,2 tricyclic tetrahydroisoquinoline compounds indicated to be useful in the treatment and prophylaxis of epilepsy, migraine and other disorders |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1102769B1 (cs) |
| JP (1) | JP2002522436A (cs) |
| KR (1) | KR20010072262A (cs) |
| CN (1) | CN1324359A (cs) |
| AR (1) | AR020002A1 (cs) |
| AT (1) | ATE237615T1 (cs) |
| AU (1) | AU754638B2 (cs) |
| BR (1) | BR9912707A (cs) |
| CA (1) | CA2339362A1 (cs) |
| CO (1) | CO5080783A1 (cs) |
| CZ (1) | CZ293667B6 (cs) |
| DE (1) | DE69906985T2 (cs) |
| DK (1) | DK1102769T3 (cs) |
| ES (1) | ES2197665T3 (cs) |
| GB (1) | GB9817028D0 (cs) |
| HU (1) | HUP0103311A3 (cs) |
| IL (1) | IL141164A0 (cs) |
| NO (1) | NO20010584L (cs) |
| NZ (1) | NZ509685A (cs) |
| PL (1) | PL346167A1 (cs) |
| PT (1) | PT1102769E (cs) |
| TR (1) | TR200100364T2 (cs) |
| TW (1) | TW518334B (cs) |
| WO (1) | WO2000008020A2 (cs) |
| ZA (1) | ZA200100902B (cs) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2015DN01662A (cs) | 2012-09-18 | 2015-07-03 | Auspex Pharmaceuticals Inc | |
| US9550780B2 (en) | 2012-09-18 | 2017-01-24 | Auspex Pharmaceuticals, Inc. | Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| WO2015077521A1 (en) * | 2013-11-22 | 2015-05-28 | Auspex Pharmaceuticals, Inc. | Benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| CA2930744A1 (en) | 2013-12-03 | 2015-06-11 | Auspex Pharmaceuticals, Inc. | Methods of manufacturing benzoquinoline compounds |
| WO2016144901A1 (en) | 2015-03-06 | 2016-09-15 | Auspex Pharmaceuticals, Inc. | Methods for the treatment of abnormal involuntary movement disorders |
| CN108912118A (zh) * | 2018-07-12 | 2018-11-30 | 新乡学院 | 一种四氢异喹啉并三嗪骨架化合物及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0067565A1 (en) * | 1981-06-16 | 1982-12-22 | Beecham Group Plc | Pharmaceutically active compounds |
-
1998
- 1998-08-05 GB GBGB9817028.5A patent/GB9817028D0/en not_active Ceased
-
1999
- 1999-08-03 IL IL14116499A patent/IL141164A0/xx unknown
- 1999-08-03 BR BR9912707-5A patent/BR9912707A/pt not_active IP Right Cessation
- 1999-08-03 PT PT99941505T patent/PT1102769E/pt unknown
- 1999-08-03 CZ CZ2001436A patent/CZ293667B6/cs not_active IP Right Cessation
- 1999-08-03 CN CN99811645A patent/CN1324359A/zh active Pending
- 1999-08-03 KR KR1020017001531A patent/KR20010072262A/ko not_active Withdrawn
- 1999-08-03 TR TR2001/00364T patent/TR200100364T2/xx unknown
- 1999-08-03 WO PCT/EP1999/005584 patent/WO2000008020A2/en not_active Application Discontinuation
- 1999-08-03 AT AT99941505T patent/ATE237615T1/de not_active IP Right Cessation
- 1999-08-03 ES ES99941505T patent/ES2197665T3/es not_active Expired - Lifetime
- 1999-08-03 AU AU55098/99A patent/AU754638B2/en not_active Ceased
- 1999-08-03 EP EP99941505A patent/EP1102769B1/en not_active Expired - Lifetime
- 1999-08-03 HU HU0103311A patent/HUP0103311A3/hu unknown
- 1999-08-03 JP JP2000563653A patent/JP2002522436A/ja active Pending
- 1999-08-03 PL PL99346167A patent/PL346167A1/xx not_active Application Discontinuation
- 1999-08-03 NZ NZ509685A patent/NZ509685A/en unknown
- 1999-08-03 DK DK99941505T patent/DK1102769T3/da active
- 1999-08-03 DE DE69906985T patent/DE69906985T2/de not_active Expired - Fee Related
- 1999-08-03 CA CA002339362A patent/CA2339362A1/en not_active Abandoned
- 1999-08-04 AR ARP990103876A patent/AR020002A1/es not_active Application Discontinuation
- 1999-08-04 CO CO99049308A patent/CO5080783A1/es unknown
- 1999-08-27 TW TW088114673A patent/TW518334B/zh not_active IP Right Cessation
-
2001
- 2001-02-01 ZA ZA200100902A patent/ZA200100902B/en unknown
- 2001-02-02 NO NO20010584A patent/NO20010584L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TW518334B (en) | 2003-01-21 |
| HUP0103311A3 (en) | 2002-10-28 |
| CN1324359A (zh) | 2001-11-28 |
| DE69906985T2 (de) | 2004-02-12 |
| DK1102769T3 (da) | 2003-08-11 |
| AU5509899A (en) | 2000-02-28 |
| ES2197665T3 (es) | 2004-01-01 |
| NZ509685A (en) | 2003-07-25 |
| ZA200100902B (en) | 2002-05-14 |
| HUP0103311A2 (hu) | 2002-02-28 |
| CZ293667B6 (cs) | 2004-06-16 |
| KR20010072262A (ko) | 2001-07-31 |
| CA2339362A1 (en) | 2000-02-17 |
| CZ2001436A3 (cs) | 2001-08-15 |
| NO20010584D0 (no) | 2001-02-02 |
| HK1037919A1 (en) | 2002-02-22 |
| BR9912707A (pt) | 2001-11-06 |
| AR020002A1 (es) | 2002-03-27 |
| WO2000008020A3 (en) | 2000-07-13 |
| AU754638B2 (en) | 2002-11-21 |
| EP1102769A2 (en) | 2001-05-30 |
| WO2000008020A8 (en) | 2001-04-26 |
| ATE237615T1 (de) | 2003-05-15 |
| WO2000008020A2 (en) | 2000-02-17 |
| EP1102769B1 (en) | 2003-04-16 |
| NO20010584L (no) | 2001-02-02 |
| JP2002522436A (ja) | 2002-07-23 |
| PT1102769E (pt) | 2003-08-29 |
| GB9817028D0 (en) | 1998-09-30 |
| CO5080783A1 (es) | 2001-09-25 |
| DE69906985D1 (en) | 2003-05-22 |
| PL346167A1 (en) | 2002-01-28 |
| TR200100364T2 (tr) | 2001-09-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2291266B (en) | Improvements in or relating to the formation of semiconductor devices | |
| PL348817A1 (en) | Compositions and methods for the treatment of anorectal disorders | |
| GB0106183D0 (en) | Improvements in or relating to the treatment of lesions | |
| HUP0302492A3 (en) | Methods and compositions for the prevention of tolerance to medications | |
| PL330496A1 (en) | Methods of and compositions for treating and preventing tumours, disorders associated with tumours as well as cachexy | |
| IL142908A0 (en) | Compounds useful in the treatment of inflammatory diseases | |
| HUP0100786A3 (en) | Substituted 2-phenyl-1-(3,4-dihydroxy-5-nitrophenyl)-1-ethanones, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them | |
| IL156340A0 (en) | 3-indoline derivatives useful in the treatment of psychiatric and neurologic disorders | |
| AU2003255993A1 (en) | Diazabicyclic compounds useful in the treatment of cns and other disorders | |
| CA2418167A1 (en) | Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses | |
| ZA951088B (en) | Use of substituted arylcyclobutylalkylamine compounds in the treatment of seizures neurological disorders and neurological damage | |
| AU2002215047A1 (en) | Isoquinoline derivatives useful in the treatment of cns disorders | |
| GB9816234D0 (en) | Compounds for use in the treatment of inflammation | |
| PL344011A1 (en) | Process for the preparation of sertraline and its 1,r-stereoisomer | |
| IL141164A0 (en) | 1,2 tricyclic tetrahydroisoquinoline compounds indicated to be useful in the treatment and prophylaxis of epilepsy, migraine and other disorders | |
| IL140580A0 (en) | Isoflavonoid-based therapeutic composition intended to be used in the treatment of tumours with cytotoxic agents | |
| PL345110A1 (en) | Aza-heterocyclic compounds used to treat neurological disorders and hair loss | |
| GB2295827B (en) | Additive for the prevention of nitrosamine formation in silicone articles | |
| IL140588A0 (en) | Therapeutic composition based on flavonoids intended to be used in the treatment of tumours by cytotoxic agents | |
| PL332603A1 (en) | Application of 1-hydroxy-2-pyridinones in treating seborrhoic dermatitis | |
| IL156045A0 (en) | Compositions containing gangliosides for use in the treatment of skin disorders | |
| IL129460A0 (en) | Use of lofexidine in the treatment of behavioral disorders | |
| HUP9902802A3 (en) | Pyridyl- and pyrimidyl-piperazines in the treatment of substance abuse disorders | |
| IL133398A0 (en) | (s) 2-methylamino-2-phenyl - n-butyl 3,4,5 - trimethoxybenzoate and its application to the treatment of chronic pain | |
| EP1315499A4 (en) | COMPOSITIONS AND METHODS OF TREATING ANORCAL DISEASES |