IL137003A0 - Method for producing doxazodin mesylate in a crystal modification designated as form a and intermediate product for producing the same - Google Patents

Method for producing doxazodin mesylate in a crystal modification designated as form a and intermediate product for producing the same

Info

Publication number
IL137003A0
IL137003A0 IL13700398A IL13700398A IL137003A0 IL 137003 A0 IL137003 A0 IL 137003A0 IL 13700398 A IL13700398 A IL 13700398A IL 13700398 A IL13700398 A IL 13700398A IL 137003 A0 IL137003 A0 IL 137003A0
Authority
IL
Israel
Prior art keywords
producing
mesylate
doxazodin
same
intermediate product
Prior art date
Application number
IL13700398A
Other languages
English (en)
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of IL137003A0 publication Critical patent/IL137003A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13700398A 1998-01-06 1998-12-18 Method for producing doxazodin mesylate in a crystal modification designated as form a and intermediate product for producing the same IL137003A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19800214A DE19800214A1 (de) 1998-01-06 1998-01-06 Verfahren zur Herstellung von Doxazosin-Mcsylat in einer als Form A bezeichneten Kristallmodifikation und ein Zwischenprodukt dafür
PCT/EP1998/008360 WO1999035143A1 (de) 1998-01-06 1998-12-18 Verfahren zur herstellung von doxazosin-mesylat in einer als form a bezeichneten kristallmodifikation und ein zwischenprodukt für deren herstellung
CZ20002403A CZ20002403A3 (cs) 1998-01-06 1998-12-18 Způsob přípravy doxazosinmesylátu v krystalické modifikaci, označované jako forma A a meziprodukt pro tento způsob

Publications (1)

Publication Number Publication Date
IL137003A0 true IL137003A0 (en) 2001-06-14

Family

ID=37719223

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13700398A IL137003A0 (en) 1998-01-06 1998-12-18 Method for producing doxazodin mesylate in a crystal modification designated as form a and intermediate product for producing the same

Country Status (16)

Country Link
US (1) US6500830B1 (xx)
EP (1) EP1060177B1 (xx)
JP (1) JP2002500223A (xx)
CN (1) CN1285829A (xx)
AT (1) ATE335736T1 (xx)
AU (1) AU2275199A (xx)
CA (1) CA2317523A1 (xx)
CZ (1) CZ20002403A3 (xx)
DE (3) DE19800214A1 (xx)
ES (1) ES2268812T3 (xx)
HU (1) HUP0100716A2 (xx)
IL (1) IL137003A0 (xx)
IS (1) IS5558A (xx)
SI (1) SI1060177T1 (xx)
TR (1) TR200001910T2 (xx)
WO (1) WO1999035143A1 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2164520B1 (es) * 1999-03-16 2003-04-01 Medichem Sa "procedimiento de obtencion del polimorfo a del mesilato de doxazosina"
DE19912063A1 (de) * 1999-03-18 2000-09-21 Knoll Ag Neues Verfahren zur Herstellung von Doxazosin-Mesylat in einer als Form A bezeichneten Kristallmodifikation
DE19912573A1 (de) * 1999-03-19 2000-09-21 Knoll Ag Arzneimittel, enthaltend Doxazosin-Mesylat der Kristallmodifikaton D
EP1530047A1 (en) * 2003-11-07 2005-05-11 Roche Diagnostics GmbH Proximal markers of arterial thrombosis and inflammation for risk stratification of coronary heart disease
WO2009081087A1 (en) * 2007-12-24 2009-07-02 Cipla Limited Crystalline polymorph of doxazosin mesylate (form iv) and process for preparation thereof
CN109988158A (zh) * 2018-01-03 2019-07-09 合肥立方制药股份有限公司 X晶型、含有x晶型的多沙唑嗪甲磺酸盐及其制备方法和用途
CN111303130B (zh) * 2018-12-11 2021-09-14 合肥立方制药股份有限公司 一种多沙唑嗪甲磺酸盐晶型、其制备方法及用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188390A (en) * 1977-11-05 1980-02-12 Pfizer Inc. Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
EP0459666B1 (en) * 1990-05-31 1994-11-09 Pfizer Inc. Medicaments against impotence
WO1994009783A1 (en) 1992-11-04 1994-05-11 Sepracor, Inc. Methods and compositions of (-) doxazosin for the treatment of benign prostatic hyperplasia and atherosclerosis
ES2117426T3 (es) * 1995-06-06 1998-08-01 Pfizer Forma cristalina de la sal anhidra compuesta de los acidos 7-((1a,5a,6a)-6-amino-3-azabiciclo(3.1.0.)hex-3-il)-6-fluoro-1-(2,4-difluorofenil)-1,4-dihidro-4-oxo-1,8-naftiridina-3-carboxilico y metanosulfonico.
IT1287588B1 (it) * 1996-12-13 1998-08-06 Alfa Chem Ital Forma cristallina del doxazosin mesilato e processo per la sua produzione
PT849266E (pt) * 1996-12-20 2007-03-30 Heumann Pcs Gmbh Nova forma polimorfa de mesilato de doxazosina (forma iii)
EP0849265A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von Doxazosin-Mesylat (Form II)
EP0849264A1 (de) 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von doxazosinmesylat (Form I)

Also Published As

Publication number Publication date
US6500830B1 (en) 2002-12-31
IS5558A (is) 2000-07-05
DE29824265U1 (de) 2001-04-26
ATE335736T1 (de) 2006-09-15
CA2317523A1 (en) 1999-07-15
DE19800214A1 (de) 1999-07-15
CZ20002403A3 (cs) 2000-12-13
WO1999035143A1 (de) 1999-07-15
SI1060177T1 (sl) 2006-12-31
EP1060177B1 (de) 2006-08-09
AU2275199A (en) 1999-07-26
JP2002500223A (ja) 2002-01-08
HUP0100716A2 (hu) 2002-05-29
TR200001910T2 (tr) 2000-11-21
ES2268812T3 (es) 2007-03-16
EP1060177A1 (de) 2000-12-20
CN1285829A (zh) 2001-02-28
DE59813681D1 (de) 2006-09-21

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IL137003A0 (en) Method for producing doxazodin mesylate in a crystal modification designated as form a and intermediate product for producing the same
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