IL136415A - Transmucosal formulations of levosimendan - Google Patents

Transmucosal formulations of levosimendan

Info

Publication number
IL136415A
IL136415A IL13641598A IL13641598A IL136415A IL 136415 A IL136415 A IL 136415A IL 13641598 A IL13641598 A IL 13641598A IL 13641598 A IL13641598 A IL 13641598A IL 136415 A IL136415 A IL 136415A
Authority
IL
Israel
Prior art keywords
levosimendan
patient
source
mucous membrane
transmucosal formulations
Prior art date
Application number
IL13641598A
Other languages
English (en)
Other versions
IL136415A0 (en
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of IL136415A0 publication Critical patent/IL136415A0/xx
Publication of IL136415A publication Critical patent/IL136415A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Paper (AREA)
  • Air Bags (AREA)
  • Saccharide Compounds (AREA)
IL13641598A 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan IL136415A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI974578A FI974578A (fi) 1997-12-19 1997-12-19 Menetelmä levosimendaanin antamiseksi
PCT/FI1998/000977 WO1999032081A1 (fr) 1997-12-19 1998-12-11 Formulations transmuqueuses de levosimendane

Publications (2)

Publication Number Publication Date
IL136415A0 IL136415A0 (en) 2001-06-14
IL136415A true IL136415A (en) 2005-03-20

Family

ID=8550178

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13641598A IL136415A (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan

Country Status (26)

Country Link
US (1) US6399610B1 (fr)
EP (1) EP1052973B1 (fr)
JP (1) JP2001526205A (fr)
KR (1) KR100753689B1 (fr)
AT (1) ATE215358T1 (fr)
AU (1) AU738082B2 (fr)
BR (1) BR9813641A (fr)
CA (1) CA2313618C (fr)
CZ (1) CZ296693B6 (fr)
DE (1) DE69804678T2 (fr)
DK (1) DK1052973T3 (fr)
EA (1) EA002197B1 (fr)
EE (1) EE04330B1 (fr)
ES (1) ES2175827T3 (fr)
FI (1) FI974578A (fr)
HR (1) HRP20000400B1 (fr)
HU (1) HU226736B1 (fr)
IL (1) IL136415A (fr)
NO (1) NO320050B1 (fr)
NZ (1) NZ504806A (fr)
PL (1) PL191868B1 (fr)
PT (1) PT1052973E (fr)
RS (1) RS49889B (fr)
SK (1) SK284838B6 (fr)
WO (1) WO1999032081A1 (fr)
ZA (1) ZA9811405B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI980901A (fi) * 1998-04-23 1999-10-24 Orion Yhtymae Oyj Levosimendaania säädellysti vapauttavia oraalisia koostumuksia
FI20002755A0 (fi) 2000-12-15 2000-12-15 Orion Yhtymae Oyj Menetelmä erektiilin dysfunktion hoitamiseen
CN100428937C (zh) * 2003-10-30 2008-10-29 北京海合天科技开发有限公司 左西孟旦冷冻干燥组合物
FI20040674A0 (fi) 2004-05-12 2004-05-12 Orion Corp Menetelmä tromboembolisten sairauksien estoon
JP5577021B2 (ja) * 2005-02-17 2014-08-20 アボット・ラボラトリーズ 動物における障害を治療および予防するための薬剤組成物の経粘膜投与
JP2008530186A (ja) * 2005-02-18 2008-08-07 オリオン コーポレーション 心不全治療法
WO2007096906A2 (fr) * 2006-02-27 2007-08-30 Panacea Biotec Ltd. Nouvelles compositions bucco-adhésives et procédé d'élaboration desdites compositions
CA2660362C (fr) 2006-09-27 2018-03-20 Niconovum Ab Utilisation d'un dispositif ou d'un pulverisateur pour l'administration orale d'un liquide contenant une substance active pour une absorption amelioree
EP3941450A4 (fr) * 2019-03-22 2022-12-21 Dbbh, Llc Antihistaminiques administrés par voie intranasale et utilisations associées
CA3145456A1 (fr) * 2019-07-01 2021-01-07 Orion Corporation Procedes d'administration de(r)-n-[4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]acetamide
JP2023507626A (ja) 2019-12-16 2023-02-24 テナックス・セラピューティクス，インコーポレイテッド 駆出率が保たれた心不全を伴う肺高血圧症（ＰＨ－ＨＦ－ｐＥＦ）を治療するためのレボシメンダン

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
GB2266841A (en) * 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
US5688520A (en) * 1995-03-29 1997-11-18 Minnesota Mining And Manufacturing Company Transmucosal delivery of melatonin for prevention of migraine
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan

Also Published As

Publication number Publication date
FI974578A0 (fi) 1997-12-19
CA2313618A1 (fr) 1999-07-01
NO320050B1 (no) 2005-10-17
WO1999032081A1 (fr) 1999-07-01
HU226736B1 (en) 2009-08-28
EP1052973B1 (fr) 2002-04-03
EA002197B1 (ru) 2002-02-28
DE69804678D1 (de) 2002-05-08
PL191868B1 (pl) 2006-07-31
DE69804678T2 (de) 2002-11-21
NO20003059D0 (no) 2000-06-14
PT1052973E (pt) 2002-09-30
IL136415A0 (en) 2001-06-14
EA200000686A1 (ru) 2000-12-25
ATE215358T1 (de) 2002-04-15
EE04330B1 (et) 2004-08-16
EP1052973A1 (fr) 2000-11-22
AU738082B2 (en) 2001-09-06
US6399610B1 (en) 2002-06-04
SK9062000A3 (en) 2000-12-11
JP2001526205A (ja) 2001-12-18
HRP20000400B1 (en) 2009-06-30
CA2313618C (fr) 2008-02-05
CZ20002155A3 (cs) 2000-11-15
ES2175827T3 (es) 2002-11-16
RS49889B (sr) 2008-08-07
NZ504806A (en) 2001-09-28
DK1052973T3 (da) 2002-04-29
HUP0100452A2 (hu) 2002-02-28
HUP0100452A3 (en) 2002-03-28
EE200000368A (et) 2001-10-15
FI974578A (fi) 1999-06-20
NO20003059L (no) 2000-06-14
AU1565699A (en) 1999-07-12
ZA9811405B (en) 1999-06-11
HRP20000400A2 (en) 2000-12-31
SK284838B6 (sk) 2005-12-01
KR20010033368A (ko) 2001-04-25
YU36900A (sh) 2003-02-28
KR100753689B1 (ko) 2007-08-30
CZ296693B6 (cs) 2006-05-17
PL341202A1 (en) 2001-03-26
BR9813641A (pt) 2000-10-17

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees