IL134656A - Antibodies which bind a noggin polypeptide and hybridoma capable of producing such antibodies - Google Patents

Antibodies which bind a noggin polypeptide and hybridoma capable of producing such antibodies

Info

Publication number
IL134656A
IL134656A IL134656A IL13465693A IL134656A IL 134656 A IL134656 A IL 134656A IL 134656 A IL134656 A IL 134656A IL 13465693 A IL13465693 A IL 13465693A IL 134656 A IL134656 A IL 134656A
Authority
IL
Israel
Prior art keywords
noggin
embryos
leu
neural
seq
Prior art date
Application number
IL134656A
Other languages
English (en)
Original Assignee
Univ California
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Regeneron Pharma filed Critical Univ California
Publication of IL134656A publication Critical patent/IL134656A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL134656A 1992-09-03 1993-09-02 Antibodies which bind a noggin polypeptide and hybridoma capable of producing such antibodies IL134656A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93995492A 1992-09-03 1992-09-03
US95041092A 1992-09-23 1992-09-23
US95740192A 1992-10-06 1992-10-06

Publications (1)

Publication Number Publication Date
IL134656A true IL134656A (en) 2006-12-10

Family

ID=27420696

Family Applications (2)

Application Number Title Priority Date Filing Date
IL134656A IL134656A (en) 1992-09-03 1993-09-02 Antibodies which bind a noggin polypeptide and hybridoma capable of producing such antibodies
IL106894A IL106894A0 (en) 1992-09-03 1993-09-02 Dorsal tissue affecting factor and compositions

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL106894A IL106894A0 (en) 1992-09-03 1993-09-02 Dorsal tissue affecting factor and compositions

Country Status (8)

Country Link
US (4) US5843775A (de)
EP (1) EP0656062B1 (de)
JP (1) JP3431153B2 (de)
AT (1) ATE190352T1 (de)
AU (1) AU676847B2 (de)
DE (1) DE69328025T2 (de)
IL (2) IL134656A (de)
WO (1) WO1994005791A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843775A (en) * 1992-09-03 1998-12-01 Regeneron Pharmaceuticals, Inc. Human dorsal tissue affecting factor (noggin) and nucleic acids encoding same
US5679783A (en) * 1994-11-22 1997-10-21 The Regents Of The University Of California DNA encoding a tissue differentiation affecting factor
US6133232A (en) * 1996-06-20 2000-10-17 The Regents Of The University Of California Endoderm, cardiac and neural inducing factors
AU6267098A (en) * 1997-02-05 1998-08-25 Regents Of The University Of California, The Morphogenic proteins
CA2282302A1 (en) * 1997-02-19 1998-08-27 Regeneron Pharmaceuticals, Inc. Morphogenic proteins
US6075007A (en) * 1997-07-17 2000-06-13 Regeneron Pharmaceuticals, Inc. Modified noggin polypeptide and compositions
WO1999061044A1 (en) * 1998-05-28 1999-12-02 The Board Of Trustees Of The University Of Arkansas Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption
US6087168A (en) 1999-01-20 2000-07-11 Cedars Sinai Medical Center Conversion of non-neuronal cells into neurons: transdifferentiation of epidermal cells
WO2000064460A2 (en) * 1999-04-23 2000-11-02 Sulzer Orthopedics Ltd. Composition for enhancing functional recovery of a mammal from central and/or peripheral nervous system injury of traumatic or pathological origin
JP4795616B2 (ja) * 2000-06-20 2011-10-19 イーエス・セル・インターナショナル・プライヴェート・リミテッド Ｂｍｐ−２経路アンタゴニストの存在下においてｅｓ細胞を培養することによって胚性幹細胞の分化をコントロールする方法
EP1357828A2 (de) * 2001-01-12 2003-11-05 University of Medicine and Dentistry of New Jersey Knochenmorphogenetisches protein-2 bei der behandlung und diagnose von krebs
US20020197648A1 (en) * 2001-05-02 2002-12-26 Silva Robin M. High throughput screening methods using magnetic resonance imaging agents
US20030134790A1 (en) * 2002-01-11 2003-07-17 University Of Medicine And Dentistry Of New Jersey Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer
GB2385052A (en) * 2002-02-05 2003-08-13 Leuven K U Res & Dev Treatment of spondyloarthropathies
AU2006289667A1 (en) * 2005-09-08 2007-03-15 Apollo Life Sciences Limited Noggin and chimeric molecules thereof
KR101163171B1 (ko) * 2009-01-20 2012-07-19 (주)케어젠 노긴?유래 펩타이드 및 그의 용도
WO2010147803A2 (en) * 2009-06-08 2010-12-23 Regents Of The University Of Michigan Adult cerebellum-derived neural stem cells and compositions and methods for producing oligodendrocytes
WO2015009710A1 (en) * 2013-07-18 2015-01-22 Ann And Robert H. Lurie Children's Hospital Of Chicago, Et Al Compositions and methods of detecting and treating neural tube defects
WO2015134770A1 (en) * 2014-03-07 2015-09-11 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Treating soft tissue via controlled drug release
AT521641B1 (de) * 2018-09-12 2020-07-15 Fianostics Gmbh Verfahren zur Diagnose von Lebererkrankungen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0171407B1 (de) * 1984-01-30 1993-11-18 Imperial Cancer Research Technology Limited Verbesserungen an wachstumsfaktoren
WO1986006096A1 (en) * 1985-04-11 1986-10-23 The Children's Medical Center Corporation Von willebrand factor
US5030576A (en) * 1986-04-30 1991-07-09 Genentech, Inc. Receptors for efficient determination of ligands and their antagonists or agonists
US4857637A (en) * 1986-05-07 1989-08-15 Genentech, Inc. Methods and compositions for immunologically modulating growth hormone receptor activity
US5219759A (en) * 1987-04-22 1993-06-15 Chiron Corporation Recombinant DNA encoding PDGF A-chain polypeptide and expression vectors
US5229500A (en) * 1989-08-30 1993-07-20 Regeneron Pharmaceuticals, Inc. Brain derived neurotrophic factor
US5177197A (en) * 1990-02-27 1993-01-05 Ludwig Institute For Cancer Research Isolated nucleotide sequence expressing human transforming growth factor-β1-binding protein
US5364769A (en) * 1990-09-25 1994-11-15 Genentech, Inc. Nucleic acid encoding neurotrophic factor four (NT-4), vectors, host cells and methods of production
EP0550665B1 (de) * 1990-09-25 1996-07-31 Genentech, Inc. Neuer neurotropischer faktor
CA2122491A1 (en) * 1991-10-31 1993-05-13 Herbert Y. Lin Tgf-.beta. type receptor cdnas and uses therefor
DE69233022T2 (de) * 1991-11-04 2004-02-12 Genetics Institute, LLC, Cambridge Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US5843775A (en) * 1992-09-03 1998-12-01 Regeneron Pharmaceuticals, Inc. Human dorsal tissue affecting factor (noggin) and nucleic acids encoding same

Also Published As

Publication number Publication date
AU4846593A (en) 1994-03-29
WO1994005791A3 (en) 1994-07-07
US6277593B1 (en) 2001-08-21
DE69328025D1 (de) 2000-04-13
WO1994005791A2 (en) 1994-03-17
US5821124A (en) 1998-10-13
IL106894A0 (en) 1994-05-30
JPH08504086A (ja) 1996-05-07
US5843775A (en) 1998-12-01
AU676847B2 (en) 1997-03-27
EP0656062A1 (de) 1995-06-07
EP0656062B1 (de) 2000-03-08
JP3431153B2 (ja) 2003-07-28
US20020102643A1 (en) 2002-08-01
HK1008347A1 (en) 1999-05-07
DE69328025T2 (de) 2000-11-02
ATE190352T1 (de) 2000-03-15

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees