IL134082A0 - Process for the preparation of [2-((8,9)-dioxo-2,6-diazabicyclo[5,2.0]-non-1(7)-en-2-yl)-ethyl]-phosphonic acid - Google Patents

Process for the preparation of [2-((8,9)-dioxo-2,6-diazabicyclo[5,2.0]-non-1(7)-en-2-yl)-ethyl]-phosphonic acid

Info

Publication number
IL134082A0
IL134082A0 IL13408298A IL13408298A IL134082A0 IL 134082 A0 IL134082 A0 IL 134082A0 IL 13408298 A IL13408298 A IL 13408298A IL 13408298 A IL13408298 A IL 13408298A IL 134082 A0 IL134082 A0 IL 134082A0
Authority
IL
Israel
Prior art keywords
ethyl
dioxo
ester
phosphonic acid
diazabicyclo
Prior art date
Application number
IL13408298A
Other languages
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IL134082A0 publication Critical patent/IL134082A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL13408298A 1997-08-01 1998-07-31 Process for the preparation of [2-((8,9)-dioxo-2,6-diazabicyclo[5,2.0]-non-1(7)-en-2-yl)-ethyl]-phosphonic acid IL134082A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90509197A 1997-08-01 1997-08-01
PCT/US1998/015841 WO1999006417A1 (en) 1997-08-01 1998-07-31 Process for the preparation of [2-((8,9)- dioxo-2,6-diazabicyclo [5.2.0]-non-1(7)-en-2-yl)-ethyl] phosphonic acid

Publications (1)

Publication Number Publication Date
IL134082A0 true IL134082A0 (en) 2001-04-30

Family

ID=25420284

Family Applications (2)

Application Number Title Priority Date Filing Date
IL163574A IL163574A (en) 1997-08-01 1998-07-31 Process for the preparation of D. ester of N - [3 - (Butylcoscarbonylamino tart) - profile] - 2 - Aminoethyl phosphonic acid
IL13408298A IL134082A0 (en) 1997-08-01 1998-07-31 Process for the preparation of [2-((8,9)-dioxo-2,6-diazabicyclo[5,2.0]-non-1(7)-en-2-yl)-ethyl]-phosphonic acid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL163574A IL163574A (en) 1997-08-01 1998-07-31 Process for the preparation of D. ester of N - [3 - (Butylcoscarbonylamino tart) - profile] - 2 - Aminoethyl phosphonic acid

Country Status (19)

Country Link
EP (1) EP1000072B1 (xx)
JP (1) JP4383651B2 (xx)
KR (1) KR100606580B1 (xx)
CN (2) CN1149218C (xx)
AT (1) ATE232875T1 (xx)
AU (1) AU746119B2 (xx)
BR (1) BR9811807A (xx)
CA (1) CA2297411C (xx)
DE (1) DE69811507T2 (xx)
DK (1) DK1000072T3 (xx)
ES (1) ES2190091T3 (xx)
HK (1) HK1027814A1 (xx)
HU (1) HUP0002505A3 (xx)
IL (2) IL163574A (xx)
NO (1) NO325420B1 (xx)
NZ (1) NZ502509A (xx)
RU (1) RU2205834C2 (xx)
SI (1) SI1000072T1 (xx)
WO (1) WO1999006417A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA78529C2 (en) 2001-10-10 2007-04-10 Wyeth Corp Derivatives of [[2-(amino-3,4-dioxo-1-cyclobutene-1-yl)amino]alkyl] acid for treating pain
PL1611144T3 (pl) 2003-04-09 2011-03-31 Wyeth Llc Pochodne kwasu 2-(8,9-diokso-2,6-diazabicyklo(5.2.0)non-1(7)-en-2-ylo)alkilofosfonowego i ich zastosowanie jako antagonistów receptora N-metylo-D-asparaginianu (NMDA)
TW200514775A (en) 2003-10-22 2005-05-01 Wyeth Corp Methods for the preparation of {2-[(8,9)-dioxo-2,6-diaza-bicyclo[5.2.0]-non-1(7)-en-2-yl]ethyl} phosphonic acid and esters thereof
CN102356087A (zh) * 2009-03-19 2012-02-15 惠氏有限责任公司 [2-(8,9-二氧代-2,6-二氮杂双环[5.2.0]壬-1(7)-烯-2-基)乙基]膦酸及其前体的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168103A (en) * 1991-01-22 1992-12-01 American Home Products Corporation [[2-(amino-3,4-dioxo-1-cyclobuten-1-yl) amino]alkyl]-acid derivatives

Also Published As

Publication number Publication date
HUP0002505A2 (hu) 2000-11-28
NO20000488D0 (no) 2000-01-31
KR100606580B1 (ko) 2006-08-01
DE69811507T2 (de) 2003-07-24
JP4383651B2 (ja) 2009-12-16
NO325420B1 (no) 2008-04-21
IL163574A0 (en) 2005-12-18
NO20000488L (no) 2000-01-31
HK1027814A1 (en) 2001-01-23
EP1000072A1 (en) 2000-05-17
CN1526714A (zh) 2004-09-08
IL163574A (en) 2008-06-05
AU746119B2 (en) 2002-04-18
CA2297411C (en) 2008-12-02
ATE232875T1 (de) 2003-03-15
KR20010022492A (ko) 2001-03-15
WO1999006417A1 (en) 1999-02-11
BR9811807A (pt) 2000-08-15
HUP0002505A3 (en) 2002-02-28
CN1149218C (zh) 2004-05-12
JP2001512129A (ja) 2001-08-21
CA2297411A1 (en) 1999-02-11
CN1257174C (zh) 2006-05-24
SI1000072T1 (en) 2003-06-30
NZ502509A (en) 2002-08-28
ES2190091T3 (es) 2003-07-16
DE69811507D1 (de) 2003-03-27
CN1265664A (zh) 2000-09-06
AU8603798A (en) 1999-02-22
DK1000072T3 (da) 2003-04-22
RU2205834C2 (ru) 2003-06-10
EP1000072B1 (en) 2003-02-19

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IL134082A0 (en) Process for the preparation of [2-((8,9)-dioxo-2,6-diazabicyclo[5,2.0]-non-1(7)-en-2-yl)-ethyl]-phosphonic acid
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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees